Cerebral white matter microstructural changes in isolated maxillofacial trauma and associated neuropsychological outcomes

Cerebral white matter microstructural changes in isolated maxillofacial trauma and associated neuropsychological outcomes:



Isolated traumatic maxillofacial injury without concomitant brain injury may cause delayed post-concussive symptoms. Early identification allows optimal diagnosis, prognostication, and therapeutic intervention. The aim of this prospective observational study was to investigate longitudinal microstructural changes of the white matter (WM) tracts based on diffusion tensor imaging (DTI) indices in patients with isolated maxillofacial injuries, immediately and 6 months post-trauma, and to correlate these DTI indices with neuropsychological changes observed.