Cancers, Vol. 12, Pages 800: A Nine-Gene Signature for Predicting the Response to Preoperative Chemoradiotherapy in Patients with Locally Advanced Rectal Cancer Cancers doi: 10.3390/cancers12040800 Authors: In Ja Park Yun Suk Yu Bilal Mustafa Jin Young Park Yong Bae Seo Gun-Do Kim Jinpyo Kim Chang Min Kim Hyun Deok Noh Seung-Mo Hong Yeon Wook Kim Mi-Ju Kim Adnan Ahmad Ansari Luigi Buonaguro Sung-Min Ahn Chang-Sik Yu Preoperative...
Cancers, Vol. 12, Pages 799: Ionizing Radiation and Complex DNA Damage: Quantifying the Radiobiological Damage Using Monte Carlo Simulations Cancers doi: 10.3390/cancers12040799 Authors: Konstantinos P. Chatzipapas Panagiotis Papadimitroulas Dimitris Emfietzoglou Spyridon A. Kalospyros Megumi Hada Alexandros G. Georgakilas George C. Kagadis Ionizing radiation is a common tool in medical procedures. Monte Carlo (MC) techniques are widely used when dosimetry...
Cancers, Vol. 12, Pages 798: External Beam Radiation Therapy and Enadenotucirev: Inhibition of the DDR and Mechanisms of Radiation-Mediated Virus Increase Cancers doi: 10.3390/cancers12040798 Authors: Tzveta D. Pokrovska Egon J. Jacobus Rathi Puliyadi Remko Prevo Sally Frost Arthur Dyer Richard Baugh Gonzalo Rodriguez-Berriguete Kerry Fisher Giovanna Granata Katharine Herbert William K. Taverner Brian R. Champion Geoff S. Higgins Len...
Cancers, Vol. 12, Pages 797: Artificial Intelligence and Digital Microscopy Applications in Diagnostic Hematopathology Cancers doi: 10.3390/cancers12040797 Authors: Hanadi El El Achi Joseph D. Khoury Digital Pathology is the process of converting histology glass slides to digital images using sophisticated computerized technology to facilitate acquisition, evaluation, storage, and portability of histologic information. By its nature, digitization of analog histology data renders...
Cancers, Vol. 12, Pages 796: Risk of Alzheimer’s Disease in Cancer Patients: Analysis of Mortality Data from the US SEER Population-Based Registries Cancers doi: 10.3390/cancers12040796 Authors: Roman Mezencev Yury O. Chernoff Previous studies have reported an inverse association between cancer and Alzheimer’s disease (AD), which are leading causes of human morbidity and mortality. We analyzed the SEER (Surveillance, Epidemiology, and End Results) data to estimate...
Cancers, Vol. 12, Pages 794: Treatment of Combined Hepatocellular and Cholangiocarcinoma Cancers doi: 10.3390/cancers12040794 Authors: Simona Leoni Vito Sansone Stefania De Lorenzo Luca Ielasi Francesco Tovoli Matteo Renzulli Rita Golfieri Daniele Spinelli Fabio Piscaglia Combined hepatocellular and cholangiocarcinoma (HCC-CC) is a rare primary liver cancer. It is constituted by neoplastic cells of both hepatocellular and cholangiocellular derivation....
Cancers, Vol. 12, Pages 793: Safety and Activity of the Combination of Ceritinib and Dasatinib in Osteosarcoma Cancers doi: 10.3390/cancers12040793 Authors: Olaf Beck Claudia Paret Alexandra Russo Jürgen Burhenne Margaux Fresnais Kevin Steimel Larissa Seidmann Daniel-Christoph Wagner Nadine Vewinger Nadine Lehmann Maximilian Sprang Nora Backes Lea Roth Marie Astrid Neu Arthur Wingerter Nicole Henninger Khalifa El Malki Henrike...
Cancers, Vol. 12, Pages 792: Analysis of HPV-Positive and HPV-Negative Head and Neck Squamous Cell Carcinomas and Paired Normal Mucosae Reveals Cyclin D1 Deregulation and Compensatory Effect of Cyclin D2 Cancers doi: 10.3390/cancers12040792 Authors: Jiří Novotný Veronika Bandúrová Hynek Strnad Martin Chovanec Miluše Hradilová Jana Šáchová Martin Šteffl Josipa Grušanović Roman Kodet Václav Pačes Lukáš Lacina Karel Smetana Jr. Jan Plzák Michal...
Cancers, Vol. 12, Pages 795: Tetraspanin CD9 is Regulated by miR-518f-5p and Functions in Breast Cell Migration and In Vivo Tumor Growth Cancers doi: 10.3390/cancers12040795 Authors: Danielle R. Bond Richard Kahl Joshua S. Brzozowski Helen Jankowski Crystal Naudin Mamta Pariyar Kelly A. Avery-Kiejda Christopher J. Scarlett Claude Boucheix William J. Muller Leonie K. Ashman Murray J. Cairns Séverine Roselli Judith Weidenhofer Breast...
Cancers, Vol. 12, Pages 790: Proteomic Discovery of Biomarkers to Predict Prognosis of High-Grade Serous Ovarian Carcinoma Cancers doi: 10.3390/cancers12040790 Authors: Se Ik Kim Minsun Jung Kisoon Dan Sungyoung Lee Cheol Lee Hee Seung Kim Hyun Hoon Chung Jae-Weon Kim Noh Hyun Park Yong-Sang Song Dohyun Han Maria Lee Initial identification of biomarkers predicting the exact prognosis of high-grade serous ovarian carcinoma (HGSOC) is important...
Cancers, Vol. 12, Pages 788: Dysregulated Pyrimidine Biosynthesis Contributes to 5-FU Resistance in SCLC Patient-Derived Organoids but Response to a Novel Polymeric Fluoropyrimidine, CF10 Cancers doi: 10.3390/cancers12040788 Authors: William H. Gmeiner Lance D. Miller Jeff W. Chou Anthony Dominijanni Lysette Mutkus Frank Marini Jimmy Ruiz Travis Dotson Karl W. Thomas Graham Parks Christina R. Bellinger Chemo-immunotherapy is central to the...
Cancers, Vol. 12, Pages 789: Blood Free-Circulating DNA Testing of Methylated RUNX3 Is Useful for Diagnosing Early Gastric Cancer Cancers doi: 10.3390/cancers12040789 Authors: Eizaburou Hideura Yutaka Suehiro Jun Nishikawa Takuya Shuto Hiroyuki Fujimura Shunsuke Ito Atsushi Goto Kouichi Hamabe Issei Saeki Takeshi Okamoto Shingo Higaki Ikuei Fujii Chieko Suzuki Tomomi Hoshida Toshihiko Matsumoto Taro Takami Isao Sakaida Takahiro...
Cancers, Vol. 12, Pages 791: Embolotherapeutic Strategies for Hepatocellular Carcinoma: 2020 Update Cancers doi: 10.3390/cancers12040791 Authors: Sirish A. Kishore Raazi Bajwa David C. Madoff Hepatocellular carcinoma (HCC) represents a significant contributor to cancer-related morbidity and mortality with increasing incidence in both developing and developed countries. Embolotherapy as a locoregional therapeutic strategy consists of trans-arterial or “bland”...
Cancers, Vol. 12, Pages 786: A Novel Role for the Tumor Suppressor Gene ITF2 in Tumorigenesis and Chemotherapy Response Cancers doi: 10.3390/cancers12040786 Authors: Olga Pernía Ana Sastre-Perona Carlos Rodriguez-Antolín Alvaro García-Guede María Palomares-Bralo Rocío Rosas Darío Sanchez-Cabrero Patricia Cruz Carmen Rodriguez MDolores Diestro Rubén Martín-Arenas Verónica Pulido Pilar Santisteban Javier de Castro Olga Vera Inmaculada...
Cancers, Vol. 12, Pages 785: Evaluation of Two EGFR Mutation Tests on Tumor and Plasma from Patients with Non-Small Cell Lung Cancer Cancers doi: 10.3390/cancers12040785 Authors: Jeong-Oh Kim Jung-Young Shin Seo Ree Kim Kab Soo Shin Joori Kim Min-Young Kim Mi-Ran Lee Yonggoo Kim Myungshin Kim Sook Hee Hong Jin Hyoung Kang Epidermal growth factor receptor (EGFR) mutation testing is essential for individualized treatment using tyrosine kinase...
Cancers, Vol. 12, Pages 787: mTORC2/Rac1 Pathway Predisposes Cancer Aggressiveness in IDH1-Mutated Glioma Cancers doi: 10.3390/cancers12040787 Authors: Yang Liu Yanxin Lu Aiguo Li Orieta Celiku Sue Han Mingyu Qian Chunzhang Yang Isocitrate dehydrogenase (IDH) mutations are common genetic abnormalities in lower grade gliomas. The neomorphic enzyme activity of IDH mutants leads to tumor formation through epigenetic alteration, dysfunction of dioxygenases, and...
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Abstract Background Poor adherence to oral antipsychotics is common in patients with schizophrenia; nonetheless, there has been no systematic review or meta-analysis on medication adherence measured by electronic adherence monitoring (EAM), considered by many as the ‘gold standard’ assessment. Methods We systematically searched MEDLINE and Embase to identify...
Abstract Background An efficient, well tolerated, and safe emergency treatment with a rapid onset of action is needed to prevent seizure clusters and to terminate prolonged seizures and status epilepticus. Objectives This study aimed to examine the efficacy, tolerability, and safety of intranasal midazolam (in-MDZ) spray in clinical practice. ...
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Abstract Bensulfuron-methyl is an herbicide widely used for weed control although its residues cause damage to other crops during crop rotations. In this study, the biodegrading activity of bensulfuron-methyl by a plant growth-promoting bacterial strain was carried out. Methylopila sp. DKT isolated from soil was determined for bensulfuron-methyl degradation and phosphate solubilization in the liquid media and soil. Moreover, the effects of the herbicide on peanut development and...
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Zusammenfassung Hintergrund Die Haltungsregulierung basiert auf komplexen Interaktionenmechanismen posturaler Subsysteme. Dabei scheint auch das Hören einen Einfluss auf die posturale Kontrolle auszuüben. Fragestellung Ziel der Arbeit war es, den Einfluss auditorischen Inputs auf die posturale Stabilität zu erfassen und unter Berücksichtigung subjektiver...
Abstract Although the history of intraoperative neuromonitoring (IONM) dates back to the 19th century, the method did not evolve further than the mere differentiation of nerves until recently. Only the development of continuous IONM (cIONM) has allowed for non-stop analysis of excitation amplitude and latency during surgical procedures, which is nowadays integrated into the software of almost all commercially available neuromonitoring devices. The objective of cIONM is real-time...
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Ultrasound artificial intelligence software and simulation developer Intelligent...Read more on AuntMinnieEurope.com
Anyone who doubts the severity of the threat posed by the COVID-19 crisis should...Read more on AuntMinnieEurope.comRelated Reading: Abbreviated breast MRI proves value for invasive cancer Women dominate in 2020 EuroMinnies awards Meet the finalists for EuroMinnies 2020 Meet the EuroMinnies 2020 semifinal candidates Kuhl brings the curtain down in Montreal
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Abstract Purpose To retrospectively evaluate blood supply to the caudate lobe of the liver from the right inferior phrenic artery (RIPA) using cone-beam computed tomography during arteriography (CBCTA-RIPA). Methods CBCTA-RIPA examinations during transarterial chemoembolization (TACE) for hepatocellular carcinoma (HCC) were collected from 2448 procedures...
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Autism Spectrum Disorder (ASD) is a neuro-developmental disorder that affects communication and behavior with a prevalence of approximately 1% worldwide. Health outcomes of interventions for ASD are largely Pa...
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Abstract Objective The aim of the study was to investigate the outcomes and prognostic factors of high-dose 131I-metaiodobenzylguanidine (131I-MIBG) therapy in patients with refractory or relapsed neuroblastoma (NBL) in Japan. Methods We retrospectively analyzed 20 patients with refractory or relapsed high-risk NBL who underwent 131I-MIBG therapy with an...
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Lactate is a robust prognostic marker for the outcome of critically ill patients. Several small studies reported that metformin users have higher lactate levels at ICU admission without a concomitant increase ...
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JPM, Vol. 10, Pages 20: Flotillin: A Promising Biomarker for Alzheimer’s Disease Journal of Personalized Medicine doi: 10.3390/jpm10020020 Authors: Angelopoulou Paudel Shaikh Piperi Alzheimer’s disease (AD) is characterized by the accumulation of beta amyloid (Aβ) in extracellular senile plaques and intracellular neurofibrillary tangles (NFTs) mainly consisting of tau protein. Although the exact etiology of the disease remains elusive, accumulating evidence...
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JSAN, Vol. 9, Pages 17: Minimization of IEEE 802.11p Packet Collision Interference through Transmission Time Shifting Journal of Sensor and Actuator Networks doi: 10.3390/jsan9020017 Authors: Martin Klapez Carlo Augusto Grazia Maurizio Casoni V2I communications are characterized by the presence of network nodes in vehicles and in the infrastructures that these vehicles use, as well as by the wireless interactions among them. Safety-related applications demand stringent requirements...
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by Mykhaylo Usyk, Christine P. Zolnik, Philip E. Castle, Carolina Porras, Rolando Herrero, Ana Gradissimo, Paula Gonzalez, Mahboobeh Safaeian, Mark Schiffman, Robert D. Burk, Costa Rica HPV Vaccine Trial (CVT) Group Background Human papillomavirus (HPV) infection is one of the most common sexually transmitted infections. However, only a small percentage of high-risk (HR) HPV infections progress to cervical precancer and cancer. In this study, we investigated the role of the cervicovaginal microbiome...
by Stephanie N. Langel, Claire E. Otero, David R. Martinez, Sallie R. Permar
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Publication date: Available online 26 March 2020Source: Biochimica et Biophysica Acta (BBA) - General SubjectsAuthor(s): Lei Huang, Michelle Wright, Sichun Yang, Lydia Blachowicz, Lee Makowski, Benoît Roux
Publication date: Available online 25 March 2020Source: Biochimica et Biophysica Acta (BBA) - General SubjectsAuthor(s): Carlos A.H. Fernandes, Edna Gicela O. Morea, Gabriel A. dos Santos, Vitor L. da Silva, Marina Roveri Vieira, Maria Alejandra Viviescas, Jean Chatain, Aurélie Vadel, Carole Saintomé, Marcos Roberto M. Fontes, Maria Isabel Nogueira Cano
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Publication date: 1 May 2020Source: Cancer Letters, Volume 477Author(s):
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Since 2014, CardioScape has been the most comprehensive database on cardiovascular research in Europe. The database aims to outline the current cardiovascular research and innovation landscape across Europe, providing information on the distribution and focus of funding in the cardiovascular field across Europe, and establishing the extent of duplication across national research programs and the existence of gaps that reduce opportunities for innovation.
Something old, something new: a paradigm for considering immune therapies for cardiovascular disease
InflammationColchicineCoronary artery disease
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Tissue Engineering Part A, Ahead of Print.
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