Related Articles Dual role of sirtuin 1 in inflammatory bowel disease. Immunopharmacol Immunotoxicol. 2020 Jul 03;:1-22 Authors: Bansal K, Singh N, Jaggi AS Abstract Silent information regulator-1 (SIRT-1), is a member of the class III group of histone deacetylases and is collectively called sirtuins. There have been preclinical and clinical studies indicating the downregulation and decreased activity of sirtuin 1 in various inflammatory bowel...
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Related Articles Leukostasis in Chronic Lymphocytic Leukemia. Am J Case Rep. 2020 Jul 03;21:e924798 Authors: Singh N, Singh Lubana S, Dabrowski L, Sidhu G Abstract BACKGROUND Chronic lymphocytic leukemia (CLL) is a mature B cell lymphocytic neoplasm that has an indolent clinical course. Therefore, not all patients with CLL require treatment at the time of diagnosis. Hyperleukocytosis (white blood cell count, >100×10⁹/L) is present in a large...
Sat Jul 04, 2020 13:20
Related Articles Hereditary Hemorrhagic Telangiectasia in a Sickle Cell Trait Patient: A Report of a Rare Case with Use of Nuclear Medicine, and a Literature Review. Am J Case Rep. 2020 Jul 02;21:e923355 Authors: Kang HC, Martins Pereira MA, Silva LNL, Oliveira LC, Márvila IS Abstract BACKGROUND Hereditary hemorrhagic telangiectasia (HHT), also known as Rendu-Osler-Weber syndrome, is a rare autosomal dominant disease. CASE REPORT Here, we report...
Fri Jul 03, 2020 17:28
Related Articles Valentino's Syndrome (with Retroperitoneal Ulcer Perforation): A Rare Clinico-Anatomical Entity. Am J Case Rep. 2020 Jul 02;21:e922647 Authors: Noussios G, Galanis N, Konstantinidis S, Mirelis C, Chatzis I, Katsourakis A Abstract BACKGROUND In the emergency department pain in the right lower quadrant is a frequent finding and is related to a wide variety of diseases, the most common of which is acute appendicitis. An unusual...
Fri Jul 03, 2020 13:30
Related Articles Radiomic analysis identifies tumor subtypes associated with distinct molecular and microenvironmental factors in head and neck squamous cell carcinoma. Oral Oncol. 2020 Jun 30;110:104877 Authors: Katsoulakis E, Yu Y, Apte AP, Leeman JE, Katabi N, Morris L, Deasy JO, Chan TA, Lee NY, Riaz N, Hatzoglou V, Oh JH Abstract PURPOSE: To identify whether radiomic features from pre-treatment computed tomography (CT) scans can predict...
Sun Jul 05, 2020 23:07
Related Articles Isolated limb perfusion for soft tissue sarcoma: Current practices and future directions. A survey of experts and a review of literature. Cancer Treat Rev. 2020 Jun 19;88:102058 Authors: Martin-Tellez KS, van Houdt WJ, van Coevorden F, Colombo C, Fiore M Abstract Soft tissue sarcomas constitute 1% of adult malignant tumors. They are a heterogeneous group of more than 50 different histologic types. Isolated limb perfusion is...
Sun Jul 05, 2020 23:07
Related Articles Investigation of spectroscopic and proteomic alterations underlying prostate carcinogenesis. J Proteomics. 2020 Jun 30;:103888 Authors: Felgueiras J, Silva JV, Nunes A, Fernandes I, Patrício A, Maia N, Pelech S, Fardilha M Abstract Prostate cancer (PCa) treatment remains challenging, especially in advanced stages, where the lack of sensitivity and specificity of available biomarkers makes it difficult to establish an accurate...
Sun Jul 05, 2020 23:07
Related Articles Novel antibody-drug conjugates: current and future roles in gynecologic oncology. Curr Opin Obstet Gynecol. 2020 Jun 28;: Authors: Tymon-Rosario J, Zeybek B, Santin AD Abstract PURPOSE OF REVIEW: Antibody-drug conjugates (ADCs) represent a new class of drugs that combine a surface receptor-targeting antibody linked to a cytotoxic molecule. This review summarizes the current literature demonstrating their tremendous promise...
Sun Jul 05, 2020 23:07
Related Articles Biosimilars in oncology: key role of nurses in patient education. Future Oncol. 2020 Jul 03;: Authors: Waller CF, Friganović A Abstract Biosimilars have the potential to lower costs and increase patient access to life-saving cancer therapies. However, lack of familiarity with biosimilars can be a barrier to their adoption, limiting their health and economic benefits. As highly trusted healthcare providers, nurses play integral...
Sat Jul 04, 2020 13:20
Related Articles Global On Line Fellowship in head and neck surgery and oncology. Head Neck. 2020 Jul 03;: Authors: Shah JP, O'Neil JP, Brennan MF Abstract The International Federation of Head and Neck Oncologic Societies and Memorial Sloan Kettering Cancer Center in New York have partnered to create the Global On Line Fellowship program, a postgraduate fellowship training opportunity for candidates all around the world who are not able to...
Sun Jul 05, 2020 23:07
Related Articles GammaTile®: Surgically targeted radiation therapy for glioblastomas. Future Oncol. 2020 Jul 03;: Authors: Gessler DJ, Ferreira C, Dusenbery K, Chen CC Abstract Glioblastoma is the most common primary malignant neoplasm of the central nervous system in adults. Standard of care is resection followed by chemo-radiation therapy. Despite this aggressive approach, >80% of glioblastomas recur in proximity to the resection cavity....
Sat Jul 04, 2020 13:20
Related Articles Prospective randomized trial of interventions for vincristine-related neuropathic pain. Pediatr Blood Cancer. 2020 Jul 02;:e28539 Authors: Anghelescu DL, Tesney JM, Jeha S, Wright BB, Trujillo L, Sandlund JT, Pauley J, Cheng C, Pei D, Pui CH Abstract BACKGROUND: To evaluate the efficacy of gabapentin at 20 mg/kg per day in the treatment of vincristine-related neuropathic pain. PROCEDURE: Children aged 1-18 years who...
Sun Jul 05, 2020 23:07
Related Articles Artificial intelligence in radiotherapy. Rep Pract Oncol Radiother. 2020 Jul-Aug;25(4):656-666 Authors: Siddique S, Chow JCL Abstract Artificial intelligence (AI) has already been implemented widely in the medical field in the recent years. This paper first reviews the background of AI and radiotherapy. Then it explores the basic concepts of different AI algorithms and machine learning methods, such as neural networks, that...
Sun Jul 05, 2020 23:07
Related Articles Image guidance in interventional radiology: Back to the future? Diagn Interv Imaging. 2020 Jul - Aug;101(7-8):429-430 Authors: Cornelis FH, Solomon SB PMID: 32616308 [PubMed - in process]
Sun Jul 05, 2020 23:07
Related Articles Repurposing old drugs to fight multidrug resistant cancers. Drug Resist Updat. 2020 Jun 25;52:100713 Authors: Dinić J, Efferth T, García-Sosa AT, Grahovac J, Padrón JM, Pajeva I, Rizzolio F, Saponara S, Spengler G, Tsakovska I Abstract Overcoming multidrug resistance represents a major challenge for cancer treatment. In the search for new chemotherapeutics to treat malignant diseases, drug repurposing gained a tremendous interest...
Fri Jul 03, 2020 15:08
Related Articles Treatment implications of postoperative chemoradiotherapy for squamous cell carcinoma of the oral cavity with minor and major extranodal extension. Oral Oncol. 2020 Jun 29;110:104845 Authors: de Almeida JR, Truong T, Khan NM, Su JS, Irish J, Gilbert R, Goldstein D, Huang SH, O'Sullivan B, Hosni A, Hope A, Waldron J, Hansen AR, Spreafico A, Siu LL, Perez-Ordonez B, Xu W, Weinreb I Abstract OBJECTIVES: To evaluate adjuvant chemoradiotherapy...
Fri Jul 03, 2020 15:08
Related Articles The Commonwealth: an anachronism or a relevant organisation for the future? Lancet Oncol. 2020 Jul;21(7):875-876 Authors: Collingridge D PMID: 32615103 [PubMed - as supplied by publisher]
Fri Jul 03, 2020 15:08
Related Articles Long noncoding RNA THOR is highly expressed in colorectal cancer and predicts a poor prognosis. Future Oncol. 2020 Jul 02;: Authors: Chu F, Cui Y, Li K, Xiao X, Zhang L, Zhang L, Wang L, Gao L, Yin N, Wu H Abstract Aim: Colorectal cancer (CRC) is one of the leading causes of cancer-related deaths worldwide. This study aimed to investigate the role of long noncoding RNA THOR in CRC. Materials & methods: The expression of...
Fri Jul 03, 2020 15:08
Related Articles Breast cancer risk based on adapted IBIS prediction model in Slovenian women aged 40-49 years - could it be better? Radiol Oncol. 2020 Jul 02;: Authors: Oblak T, Zadnik V, Krajc M, Lokar K, Zgajnar J Abstract Background The aim of the study was to assess the proportion of women that would be classified as at above-average risk of breast cancer based on the 10 year-risk prediction of the Slovenian breast cancer incidence rate...
Fri Jul 03, 2020 15:08
Related Articles Predictors of Post-Thrombotic Syndrome in Pediatric Thrombosis: A Systematic Review and Meta-Analysis of the Literature. J Thromb Haemost. 2020 Jul 02;: Authors: Engel ER, Nguyen ATH, Amankwah EK, Albisetti M, Brandão LR, Goldenberg NA, Betensky M Abstract BACKGROUND: Post-thrombotic syndrome (PTS) is a significant complication of pediatric deep venous thrombosis (DVT). There is a gap in the understanding of the risk factors...
Fri Jul 03, 2020 15:08
Related Articles Characterization of the Cancer Spectrum in Men With Germline BRCA1 and BRCA2 Pathogenic Variants: Results From the Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA). JAMA Oncol. 2020 Jul 02;: Authors: Silvestri V, Leslie G, Barnes DR, and the CIMBA Group, Agnarsson BA, Aittomäki K, Alducci E, Andrulis IL, Barkardottir RB, Barroso A, Barrowdale D, Benitez J, Bonanni B, Borg A, Buys SS, Caldés T, Caligo MA, Capalbo C, Campbell I, Chung...
Fri Jul 03, 2020 15:08
Related Articles Therapy options after CDK4/6 inhibitors for HR+, HER2- postmenopausal metastatic/recurrent breast cancer in Japan: a role for mammalian target of rapamycin inhibitors? Future Oncol. 2020 Jul 02;: Authors: Nakayama T, Fujisawa F Abstract Despite advances in the treatment of hormone receptor-positive, human epidermal growth factor receptor 2-negative metastatic breast cancer, the disease is rarely curable. In this review, we focus...
Fri Jul 03, 2020 15:08
Related Articles GAVeCeLT-WoCoVA Consensus on subcutaneously anchored securement devices for the securement of venous catheters: Current evidence and recommendations for future research. J Vasc Access. 2020 Jul 02;:1129729820924568 Authors: Pinelli F, Pittiruti M, Van Boxtel T, Barone G, Biffi R, Capozzoli G, Crocoli A, Elli S, Elisei D, Fabiani A, Garrino C, Graziano U, Montagnani L, Prato AP, Scoppettuolo G, Zadra N, Zanaboni C, Zerla P, Konstatinou E, Jones...
Fri Jul 03, 2020 15:08
Related Articles Characterization of the ablation zones produced by three commercially available systems from a single vendor for radiofrequency thermoablation in an ex vivo swine liver model. Vet Med Sci. 2020 Jul 01;: Authors: Bullone M, Garberoglio R, Pregel P, Cannizzo FT, Gagliardo A, Martano M, Bollo E, Scaglione FE Abstract BACKGROUND: Radiofrequency Ablation (RFA) is rarely performed in veterinary medicine. A rationale exists for its...
Fri Jul 03, 2020 13:39
Related Articles Cervical self-sampling yields useful cytology. BJOG. 2020 Jul 01;: Authors: Denton KJ Abstract Effective Cervical screening involves a complex sequence of interactions between women, clinical staff and systems. Even in well organised screening programmes, achieving high population coverage is challenging. The transition to using Human Papilloma Virus (HPV) testing as the primary screening modality, rather than cytology, has...
Fri Jul 03, 2020 13:39
Related Articles Total body irradiation in Australia and New Zealand: results of a practice survey. Phys Eng Sci Med. 2020 Jul 01;: Authors: Fog LS, Wirth A, MacManus M, Downes S, Grace M, Moggré A, Mugabe K, Neveri G, Nourbehesht L, Panettieri V, Pope D, Sim L, Stanton C, Steer B, Stewart A, Ungureanu E, Kron T Abstract Total body irradiation (TBI) is an important treatment modality for the preparation of patients for bone marrow transplants....
Fri Jul 03, 2020 13:39
Related Articles Facing the unknown: uncertain fertility in young adult survivors of childhood cancer. J Cancer Surviv. 2020 Jul 01;: Authors: Newton K, Howard AF, Thorne S, Kelly MT, Goddard K Abstract PURPOSE: The purpose of this research was to describe the challenges young adult childhood cancer survivors (ACCS) experience of living with an unknown fertility status. METHODS: In this qualitative study, we analyzed data from in-depth...
Fri Jul 03, 2020 13:39
Related Articles High-resolution peripheral quantitative computed tomography in children with osteogenesis imperfecta. Pediatr Radiol. 2020 Jul 01;: Authors: Fennimore DJ, Digby M, Paggiosi M, Arundel P, Bishop NJ, Dimitri P, Offiah AC Abstract Bone health in children with osteogenesis imperfecta is monitored using radiographs and dual-energy X-ray absorptiometry, which have limitations. High-resolution peripheral quantitative CT can non-invasively...
Fri Jul 03, 2020 13:39
Related Articles The impact of immunotherapy on the survival of pancreatic adenocarcinoma patients who do not receive definitive surgery of the tumor. Clin Transl Radiat Oncol. 2020 Sep;24:34-40 Authors: Amin S, Baine M, Meza J, Alam M, Lin C Abstract Background and Purpose: Immunotherapy has shown great efficacy in many cancers, but its role in pancreatic ductal adenocarcinoma (PDAC) remains unclear. The objective of this study was to investigate...
Fri Jul 03, 2020 13:39
Related Articles PSA decay during salvage radiotherapy for prostate cancer as a predictor of disease outcome - 5 year follow-up of a prospective observational study. Clin Transl Radiat Oncol. 2020 Sep;24:23-28 Authors: Gunnlaugsson A, Kjellén E, Bratt O, Ahlgren G, Johannesson V, Blom R, Nilsson P Abstract Background and purpose: Biochemical recurrence after prostatectomy is commonly treated with salvage radiotherapy (SRT). In this prospective...
Fri Jul 03, 2020 13:39
Related Articles A biomarker-enriched, randomized Phase II trial of adavosertib (AZD1775) plus paclitaxel and carboplatin for women with platinum-sensitive TP53-mutant ovarian cancer. Clin Cancer Res. 2020 Jul 01;: Authors: Oza AM, Estevez-Diz MDP, Grischke EM, Hall M, Marmé F, Provencher DM, Uyar DS, Weberpals JI, Wenham RM, Laing N, Tracy M, Freshwater T, Lee MA, Liu J, Qiu J, Rose S, Rubin EH, Moore KN Abstract PURPOSE: Preclinical studies...
Fri Jul 03, 2020 13:39
Related Articles Different response rates to chemotherapy between Japanese and German esophageal squamous cell carcinoma: patients may be influenced by ERCC1 or ABCB1. Future Oncol. 2020 Jul 02;: Authors: Narumiya K, Bollschweiler E, Hölscher AH, Yamamoto M, Drebber U, Alakus H, Metzger R, Warnecke-Eberz U Abstract Aim: To find out differences in biomarkers between Japanese and German patients responsible for response after neoadjuvant radio/chemotherapy...
Fri Jul 03, 2020 13:39
Related Articles Superimposed Clostridium difficile Infection During Checkpoint Inhibitor Immunotherapy-induced Colitis. J Immunother. 2019 Nov/Dec;42(9):350-353 Authors: Babacan NA, Tanvetyanon T Abstract Immunotherapy with checkpoint inhibitors (ICI) is widely used to treat a variety of neoplasms. ICI can induce an immune response against cancer; however, ICI can also induce autoimmunity, an undesirable side effect. Autoimmune colitis is...
Fri Jul 03, 2020 13:39
Related Articles Radiation Therapy for Patients with Advanced Renal Cell Carcinoma. Urol Clin North Am. 2020 Aug;47(3):399-411 Authors: Miccio JA, Oladeru OT, Jun Ma S, Johung KL Abstract Stereotactic radiosurgery and stereotactic body radiation therapy (SBRT) have led to a resurgence of the use of radiotherapy in the management of advanced renal cell carcinoma (RCC). These techniques provide excellent local control and palliation of metastatic...
Sat Jul 04, 2020 13:13
Related Articles Knowledge about cancer screening programmes in Sardinia. J Prev Med Hyg. 2019 Dec;60(4):E337-E342 Authors: Mereu A, Concu F, Dessì C, Girau M, Ionta MT, Lai L, Liori A, Masala M, McGilliard CD, Origa P, Piazza MF, Pisanu L, Soggiu B, Sotgiu A, Contu P, Sardu C Abstract Background: High level of attendance by population is considered a proof of the efficacy in the screening programmes. Public health aims to increase people's...
Sat Jul 04, 2020 13:13
Related Articles Evaluation of the Normality Assumption in Meta-Analyses. Am J Epidemiol. 2020 03 02;189(3):235-242 Authors: Wang CC, Lee WC Abstract Random-effects meta-analysis is one of the mainstream methods for research synthesis. The heterogeneity in meta-analyses is usually assumed to follow a normal distribution. This is actually a strong assumption, but one that often receives little attention and is used without justification. Although...
Sat Jul 04, 2020 13:13
Anti-αFR CAR-engineered NK-92 Cells Display Potent Cytotoxicity Against αFR-positive Ovarian Cancer.
Related Articles Anti-αFR CAR-engineered NK-92 Cells Display Potent Cytotoxicity Against αFR-positive Ovarian Cancer. J Immunother. 2019 10;42(8):284-296 Authors: Ao X, Yang Y, Li W, Tan Y, Guo W, Ao L, He X, Wu X, Xia J, Xu X, Guo J Abstract Folate receptor alpha (αFR) is overexpressed in 90% of ovarian cancers, one of the most lethal gynecologic cancers. Recent studies have suggested that natural killer (NK) cells may be better chimeric...
Sat Jul 04, 2020 13:13
30 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: Future Oncology These pubmed results were generated on 2020/07/03PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Fri Jul 03, 2020 14:53
30 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: Future Oncology These pubmed results were generated on 2020/07/03PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Fri Jul 03, 2020 13:53
Abstract Introduction Menthol topical application and mouth rinsing are ergogenic in hot environments, improving performance and perception, with differing effects on body temperature regulation. Consequently, athletes and federations are beginning to explore the possible benefits to elite sport performance for the Tokyo 2021 Olympics, which will take place in hot (~ 31 °C), humid (70% RH) conditions. There is no clear consensus on...
Sat Jul 04, 2020 03:00
Related Articles Design, synthesis and biological evaluation of 4-aniline quinazoline derivatives conjugated with hydrogen sulfide (H2S) donors as potent EGFR inhibitors against L858R resistance mutation. Eur J Med Chem. 2020 Jun 27;202:112522 Authors: Zheng YG, Zhang WQ, Meng L, Wu XQ, Zhang L, An L, Li CL, Gao CY, Xu L, Liu Y Abstract In this study, a series of 4-aniline quinazoline derivatives bearing hydrogen sulfide (H2S) donors were designed,...
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Related Articles Evolution of a concept: From accessory protein to key virulence factor, the case of HIV-1 Vpr. Biochem Pharmacol. 2020 Jun 30;:114128 Authors: Wallet C, Rohr O, Schwartz C Abstract Back in 1989 some studies have shown that the viral protein Vpr was dispensable for HIV-1 replication in vitro. From then the concept of accessory or auxiliary protein for Vpr has emerged and it is still used to date. However, Vpr soon appeared to...
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Related Articles Phenyl boronic acid-modified lipid nanocarriers of niclosamide for targeting triple-negative breast cancer. Nanomedicine (Lond). 2020 Jul 03;: Authors: Ss Pindiprolu SK, Krishnamurthy PT, Ghanta VR, Chintamaneni PK Abstract Aim: To study the active targeting efficacy of phenylboronic acid-modified niclosamide solid lipid nanoparticles (PBA-Niclo-SLN) in triple-negative breast cancer (TNBC). Materials & methods: PBA-Niclo-SLNs...
Sat Jul 04, 2020 13:03
Related Articles Depleting interferon regulatory factor-1(IRF-1) with CRISPR/Cas9 attenuates inducible oxidative metabolism without affecting RA-induced differentiation in HL-60 human AML cells. FASEB Bioadv. 2020 Jun;2(6):354-364 Authors: Zhu K, Yue J, Yen A Abstract The known collaboration between all-transretinoic acid and interferon motivates this study of the dependence of RA-induced leukemic cell differentiation on interferon regulatory...
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Related Articles Mitochondrial Substrate Utilization Regulates Cardiomyocyte Cell Cycle Progression. Nat Metab. 2020 Feb;2(2):167-178 Authors: Cardoso AC, Lam NT, Savla JJ, Nakada Y, Pereira AHM, Elnwasany A, Menendez-Montes I, Ensley EL, Petric UB, Sharma G, Sherry AD, Malloy CR, Khemtong C, Kinter MT, Tan WLW, Anene-Nzelu CG, Foo RS, Nguyen NUN, Li S, Ahmed MS, Elhelaly WM, Abdisalaam S, Asaithamby A, Xing C, Kanchwala M, Vale G, Eckert KM, Mitsche MA, McDonald...
Sat Jul 04, 2020 13:03
Related Articles Downregulation of long non-coding RNA LINP1 inhibits the malignant progression of esophageal squamous cell carcinoma. Ann Transl Med. 2020 Jun;8(11):675 Authors: Lu T, Ma K, Zhan C, Yang X, Shi Y, Jiang W, Wang H, Wang S, Wang Q, Tan L Abstract Background: Long noncoding RNA (lncRNA) in non-homologous end joining pathway 1 (LINP1) contributes to tumorigenesis in various cancers. However, little has been known about the role...
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Related Articles In vitro antitumor effect of cucurbitacin E on human lung cancer cell line and its molecular mechanism. Chin J Nat Med. 2020 Jul;18(7):483-490 Authors: Jing SY, Wu ZD, Zhang TH, Zhang J, Wei ZY Abstract Cucurbitacin E (CuE) is previously reported to exhibit antitumor effect by several means. In this study, CuE acted as a tyrosine kinase inhibitor interfering with the epidermal growth factor receptor/mitogen-activated protein...
Sat Jul 04, 2020 13:03
Related Articles Gallic acid, a phenolic acid, hinders the progression of prostate cancer by inhibition of histone deacetylase 1 and 2 expression. J Nutr Biochem. 2020 Jun 02;84:108444 Authors: Jang YG, Ko EB, Choi KC Abstract Gallic acid (GA) is known to possess diverse biological activities, including anticancer. Histone deacetylase (HDACs) are controlled by tumor suppressor gene transcription and are overexpressed in various tumors,...
Fri Jul 03, 2020 14:22
Related Articles Lentinan-functionalized selenium nanosystems with high permeability infiltrate solid tumors by enhancing transcellular transport. Nanoscale. 2020 Jul 02;: Authors: Yang F, Huang J, Liu H, Lin W, Li X, Zhu X, Chen T Abstract The delivery of nanomedicines into internal areas of solid tumors is a great challenge for the design of chemotherapeutic drugs and the realization of their successful application. Herein, we synthesized...
Fri Jul 03, 2020 14:22
Related Articles Caffeine as a tool for investigating the integration of Cdc25 phosphorylation, activity and ubiquitin-dependent degradation in Schizosaccharomyces pombe. Cell Div. 2020;15:10 Authors: Alao JP, Sunnerhagen P Abstract The evolutionarily conserved Cdc25 phosphatase is an essential protein that removes inhibitory phosphorylation moieties on the mitotic regulator Cdc2. Together with the Wee1 kinase, a negative regulator of Cdc2...
Fri Jul 03, 2020 13:22
Related Articles Transcriptional Profiles of Skeletal Muscle Associated With Increasing Severity of White Striping in Commercial Broilers. Front Physiol. 2020;11:580 Authors: Malila Y, Uengwetwanit T, Arayamethakorn S, Srimarut Y, Thanatsang KV, Soglia F, Strasburg GM, Rungrassamee W, Visessanguan W Abstract Development of the white striping (WS) abnormality adversely impacts overall quality of broiler breast meat. Its etiology remains...
Fri Jul 03, 2020 13:22
Related Articles Extracellular vesicles from adipose-derived stem cells ameliorate ultraviolet B-induced skin photoaging by attenuating reactive oxygen species production and inflammation. Stem Cell Res Ther. 2020 Jul 01;11(1):264 Authors: Xu P, Xin Y, Zhang Z, Zou X, Xue K, Zhang H, Zhang W, Liu K Abstract BACKGROUND: Large numbers of adipose-derived stem cells (ADSCs) are easily obtained and have been demonstrated to protect against ultraviolet...
Fri Jul 03, 2020 13:22
Related Articles Sequential delivery of dual drugs with nanostructured lipid carriers for improving synergistic tumor treatment effect. Drug Deliv. 2020 Dec;27(1):983-995 Authors: Xu M, Li G, Zhang H, Chen X, Li Y, Yao Q, Xie M Abstract To improve synergistic anticancer efficacy and minimize the adverse effects of chemotherapeutic drugs, temozolomide (TMZ) and curcumin (CUR) co-loaded nanostructured lipid carriers (NLCs) were prepared by...
Fri Jul 03, 2020 13:22
Related Articles Cotargeting CHK1 and PI3K Synergistically Suppresses Tumor Growth of Oral Cavity Squamous Cell Carcinoma in Patient-Derived Xenografts. Cancers (Basel). 2020 Jun 29;12(7): Authors: Yang CY, Liu CR, Chang IY, OuYang CN, Hsieh CH, Huang YL, Wang CI, Jan FW, Wang WL, Tsai TL, Liu H, Tseng CP, Chang YS, Wu CC, Chang KP Abstract Oral cavity squamous cell carcinomas (OSCCs) are aggressive tumors, and their recurrence leads to...
Fri Jul 03, 2020 13:22
Abstract Algorithms are an essential part of radiation therapy planning, which includes three optimizations problems: beam angle configuration, fluence map, and realization. This study addresses the third one, also called the leaf sequencing problem, which arises for each chosen irradiation angle, given the optimized fluence map. It consists in defining a sequence of configurations of a device (called multileaf collimator) that correctly delivers radiation to the patient. A usual...
Sat Jul 04, 2020 03:00
Abstract Achieving a high level of classification accuracy in medical datasets is a capital need for researchers to provide effective decision systems to assist doctors in work. In many domains of artificial intelligence, ensemble classification methods are able to improve the performance of single classifiers. This paper reports the state of the art of ensemble classification methods in lung cancer detection. We have performed a systematic mapping study to identify the most interesting...
Fri Jul 03, 2020 03:00
Abstract Background There is a wide variation of chewing behaviors even in healthy humans. The present study was aimed to clarify how the rheological properties of the bolus during chewing is different among individuals. We also investigated if the swallowing threshold was consistent among the individuals and if the difference in the bolus properties at the swallowing affected swallowing movement. Methods Twenty‐nine healthy volunteers were asked to ingest 8 g of steamed rice. Based on...
Fri Jul 03, 2020 21:49
Dupilumab is a receptor antagonist binding to the alpha subunit of the interleukin-4 receptor. Through binding to it, dupilumab inhibits signaling of both IL-4 and IL-13, the representative Th2 biomarkers. Rec...
Fri Jul 03, 2020 03:00
Technology in Cancer Research &Treatment, Volume 19, Issue , January-December 2020. MYO10, recognized as an important regulator of cytoskeleton remodeling, has been reported to be associated with tumorigenesis. However, its functional implication in cervical cancer and potential mechanism still remain to be undetermined currently. MYO10 level in cervical cancer tissues was analyzed by using data retrieved from The Cancer Genome Atlas and ONCOMINE databases. Messenger RNA and protein expression...
Fri Jul 03, 2020 12:30
Technology in Cancer Research &Treatment, Volume 19, Issue , January-December 2020. Purpose:To assess the efficacy and safety of stereotactic body radiation therapy using an abdominal compression technique and modified fractionation regimen (5-10 fractions) in patients with small-sized hepatocellular carcinoma.Methods:A total of 101 patients with small-sized hepatocellular carcinoma treated with stereotactic body radiation therapy using an abdominal compression technique and modified fractionation...
Thu Jul 02, 2020 12:45
Journal of Investigative Medicine High Impact Case Reports, Volume 8, Issue , January-December 2020. Thrombocytopenia 2 (THC2) is an autosomal dominant disorder characterized by ankyrin repeat domain 26 mutation and moderate thrombocytopenia. THC2 exposes patients to a low risk of bleeding and an increased likelihood of myelodysplastic syndrome/acute myeloid leukemia. Germline evaluation for a genetic disorder should be considered when a patient presents with isolated thrombocytopenia and associated...
Fri Jul 03, 2020 12:59
Journal of Investigative Medicine High Impact Case Reports, Volume 8, Issue , January-December 2020. Sarcoidosis is a multisystem granulomatous disease commonly involving the lungs and mediastinal lymph nodes with the exact etiology being unclear. The simultaneous presence of malignant disease such as breast cancer and sarcoidosis has been reported. Sarcoidosis preceding a diagnosis of malignancy and that occurring years after treatment of malignant disease has been noted in the past. The presence...
Fri Jul 03, 2020 12:58
Journal of Investigative Medicine High Impact Case Reports, Volume 8, Issue , January-December 2020. We describe the case of a 41-year-old Hispanic male, inconsistently adherent to visits and workup due to socioeconomic challenges, who presented with a right testicular mass. Because of the overriding concern that this was malignant, he underwent a right orchiectomy. Pathology revealed granulomatous disease with no evidence of malignancy. No specific diagnosis was made histologically or microbiologically...
Fri Jul 03, 2020 12:58
Background and Objectives Demand for non‐invasive body sculpting procedures has been steadily increasing, spurring the development of new energy‐based technologies. This study assessed the safety and efficacy of a new monopolar 2 MHz radiofrequency (RF) device for fat reduction of the flanks and abdomen. Study Design/Materials and Methods Nineteen subjects from two clinical sites were enrolled in this study and received a single 15‐minute treatment with the 2 MHz RF device. Up to six applicators...
Fri Jul 03, 2020 20:35
Background and Objectives Post‐inflammatory hyperpigmentation (PIH) is a common adverse effect of laser hair removal procedures. This case series emphasizes the under‐reported crescent‐shaped form of PIH that may occur following laser therapy. This case series sought to assess the potential causes of the distinct, crescent‐shaped form of PIH that may arise following laser hair removal procedures, and to examine the concept of thermal versus cryogenic damage, which was discovered accidentally due...
Fri Jul 03, 2020 20:30
Abstract Clinical studies have confirmed that the use of antibiotics, especially carbapenems, is a high-risk factor for fungal infection in preterm infants. However, it is not entirely clear whether the increased risk for fungal infection is due to the immune differences in preterm infants or antibiotic usage. We found that after newborn rats received antibiotics, they exhibited significantly impaired anti–Candida albicans immunity in...
Sat Jul 04, 2020 03:00
Abstract Atherosclerosis is a progressive chronic inflammation in the arterial walls. It is believed that the deposition of low-density lipoprotein (LDL) and its damage to endothelial cells play a vital role in atherosclerosis. Oxidized LDL (Ox-LDL) was confirmed to induce endothelial cell pyroptosis which plays an important role in intima inflammation and the development of atherosclerosis, but the underlying molecular mechanism needs...
Sat Jul 04, 2020 03:00
Abstract The genus Metakosakonia, as the closest phylogenetic neighbor of the genus Kosakonia within the family Enterobacteriaceae, when proposed in 2017, consisted of M. massiliensis JC163T and Metakosakonia spp. strains CAV1151 and GT-16. The strain CAV1151 was later classified into a novel species Phytobacter ursingii. Here, we show that the strain GT-16 shares a digital DNA-DNA hybridization (DDH) similarity of 91.0% with P. diazotrophicus DSM 17806 T and thus also belongs...
Sat Jul 04, 2020 08:33
Abstract In this study, a wild-type Pseudomonas aeruginosa strain KT1115 with the capability of converting rapeseed oils into di-rhamnolipids, a class of biosurfactants with extensive application potential, was successfully isolated and characterized. Di-rhamnolipids production by microorganism culture provided a mild, eco-friendly, and secure approach for surfactants production instead of conventional chemical synthesis. However, few studies have been attempted to explore the...
Sat Jul 04, 2020 08:33
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