Proper posture provides the best balance and body stability at minimal muscular effort. It is constantly controlled by the central nervous system, which integrates the stimuli from the proprioceptors (deep feeling sensors), vision receptors, and balance receptors through the subcortical structures. The main purpose of the study was to describe single stance stability and its correlation with the degree of scoliosis and trunk rotation among patients suffering from idiopathic scoliosis and in the control...
Sat Jul 04, 2020 11:05
Objective. Asymmetric dimethylarginine (ADMA), an endogenous inhibitor of nitric oxide (NO) synthesis, is reported to be a risk factor for cardiovascular disease. The purpose of the present study is to investigate whether ADMA is an independent predictor for future mortality and adverse clinical events among patients with heart failure (HF). Methods. Electronic literature databases (Central, MEDLINE, and Embase) were searched for relevant observational studies on the prognostic value of ADMA in HF...
Sat Jul 04, 2020 10:50
Populations of different ethnicities may present different movement capacities and muscular function adaptations. The purpose of this study was to investigate the differences of motion and loading in the lower extremity during dynamic deep squats between Asian and Caucasian individuals using OpenSim modelling technique with a customized squat-specific musculoskeletal model. Twenty-four participants joined the test performing the step-squat test, with right foot stepping side, squatting, and returning....
Sat Jul 04, 2020 10:50
Introduction. Idiopathic pulmonary arterial hypertension (IPAH) is a severe cardiopulmonary disease with a relatively low survival rate. Moreover, the pathogenesis of IPAH has not been fully recognized. Thus, comprehensive analyses of miRNA-mRNA network and potential drugs in IPAH are urgent requirements. Methods. Microarray datasets of mRNA and microRNA (miRNA) in IPAH were searched and downloaded from Gene Expression Omnibus (GEO). Differentially expressed genes (DEGs) and differentially expressed...
Sat Jul 04, 2020 10:35
Objective. Multifocality within an affected lobe (unilateral multifocality) or two lobes (bilaterality) is commonly denoted as multifocality without differentiation. Recently, there has been molecular evidence indicating that unilateral multifocality and bilaterality could be two different entities. However, few studies concerning the comparison between these two different multifocality entities have been reported. Design. A retrospective cohort study. Methods. From 2010 to 2013, in total, 949 consecutive...
Sat Jul 04, 2020 10:20
Numerous studies have reported that autophagy plays an important role in chronic wound healing, and enhancement of autophagic activity impairs cutaneous wound healing. The autophagy inhibitor Bafilomycin A1 (Baf A1) inhibits autophagy by preventing the formation of autophagosomes. This study aimed at elucidating the effect of Bafilomycin A1 on chronic refractory wound healing in diabetic mice. A total of 40 diabetic (db/db) mice and 20 nondiabetic (db/m) mice were used in this study. Full-thickness...
Fri Jul 03, 2020 09:50
Aims. More than half of the patients with sepsis would develop cardiac dysfunction, which is termed as sepsis-induced myocardial dysfunction (SIMD). Previous studies suggest that autophagy may play an important role in SIMD. The present study investigated whether miR-214-3p could attenuate SIMD by inhibiting autophagy. Main Methods. In this article, we investigated the role of autophagy in a mouse model of cecal ligation and puncture (CLP). The structure and function of hearts harvested from the...
Fri Jul 03, 2020 09:35
Background. Progressive degenerative changes in the body of elderly people lead to a decrease in physical and mental fitness. Seniors have a problem with performing tasks that involve both physical and mental health at the same time. The risk of falls increases, the consequences of which in old age may be particularly dangerous. It was decided to investigate the impact of performing exercises involving both physical and mental spheres on the dynamic agility in older women. Methods. 73 women () were...
Fri Jul 03, 2020 09:20
Allelochemicals are metabolites produced by living organisms that have a detrimental effect on other species when released into the environment. These chemicals play critical roles in the problems associated with crop replanting. Benzoic acid is a representative allelochemical found in root exudates and rhizosphere soil of crops and inhibits crop growth. The bioremediation of allelochemicals by microorganisms is an efficient decontamination process. In this research, a bacterial strain capable of...
Fri Jul 03, 2020 09:20
Neurodegenerative diseases represent nowadays one of the major health problems. Despite the efforts made to unveil the mechanism leading to neurodegeneration, it is still not entirely clear what triggers this phenomenon and what allows its progression. Nevertheless, it is accepted that neurodegeneration is a consequence of several detrimental processes, such as protein aggregation, oxidative stress, and neuroinflammation, finally resulting in the loss of neuronal functions. Starting from these evidences,...
Fri Jul 03, 2020 09:20
Bisphosphonates (BPs) are inhibitors of osteoclast-mediated bone resorption used for the treatment of multiple myeloma (MM) patients with osteolytic lesions. Bisphosphonate-induced osteonecrosis of the jaw (BONJ) is an infrequent drug-caused adverse event of these agents. Long noncoding RNAs (lncRNAs) are a set of more than 200 base pairs, noncoding RNA molecules, which are critical posttranscriptional regulators of gene expression. Our study was aimed at evaluating 17 lncRNAs, whose targets were...
Fri Jul 03, 2020 09:05
Accumulating evidence so far has shown that EBV’s miRNAs have been found to be involved in cancer progression. However, the comprehensive EBV miRNA expression profiles and their biological significance in EBV-associated diseases are not well documented. A comprehensive profiling of EBV-encoded miRNAs expressed in CAEBV, EBV-HLH, and nasopharyngeal carcinoma (NPC) patients was constructed, and the results showed that miR-BART19-3p was upregulated in all these diseases. Ectopic expression of miR-BART19-3p...
Fri Jul 03, 2020 09:05
Aims. The aim of the study was to analyze the influence gymnastics has on the quality of life (QOL) in women with grade 1 stress urinary incontinence (SUI) and to determine the relationship between the outcome and selected body weight indices: body mass index (BMI) and waist-to-hip ratio (WHR). Methods. A randomized study of 140 women (45-60 years) with grade 1 SUI. The subjects were randomly assigned to a 3-month training for pelvic floor muscles and a transverse abdominal muscle (PFM + TrA, ) or...
Fri Jul 03, 2020 08:50
Objective. An ideal sample source is critical for more reliable and sensitive early detection of nucleic acid changes associated with breast cancer. Breast milk (BM) is a good noninvasive origin for genetic testing of early breast cancer, but cells in BM are easily disintegrated. So we investigate here whether cell-free nucleic acid (cfNA) exists in BM in a more stable form and whether the quality of BM cfNA is good enough for genetic testing. Methods. A self-designed qRT-PCR method was used to measure...
Fri Jul 03, 2020 08:20
This study is aimed at assessing the willingness to participate in the HIV vaccine trials and the associated factors among people who inject drugs (PWIDs) in Tanzania. Information about the willingness to participate and the associated factors was collected using interviewer-administered questionnaires at the medication treatment for opioid use disorder (MOUD) clinic in Dar es Salaam. Data analysis was performed using the IBM SPSS Statistic 20. The mean age of respondents was 36.7, and the standard...
Fri Jul 03, 2020 06:20
Abstract Objective The main aim is to identify, by means of different imaging modalities, the early bone changes in patients “at risk” and in stage 0 MRONJ. Materials and methods A search of the literature was performed on PubMed, Embase, Web of Science, and Cochrane Library databases, until June 9, 2020. No language or year restrictions were applied. Screening...
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Abstract Objectives To evaluate the effect of ozonated water in early plaque formation and gingival inflammation. Materials and methods This was a randomized, controlled, double-blind, crossover clinical trial with two experimental periods of 96 h each, with 10 washout days between them. The sample consisted of 42 dental students divided into Test Group,...
Sat Jul 04, 2020 03:00
Abstract Objectives Connexins are building blocks of membranous channels that form gap junctions and hemichannels. These channels are essential portals for information exchange and coordination during inflammation. Pathologic levels of these conduits may result in excessive inflammation and collateral destruction. This study aimed to analyse temporospatial levels of connexin 43 (Cx43) during pulpitis in extracted human teeth and in a rodent...
Sat Jul 04, 2020 03:00
Abstract Objectives To update the findings of a systematic review from the year 2016 on the evidence for the accuracy and potential benefits of cone beam computed tomography (CBCT) in periodontal diagnostics. Material and methods A systematic literature search was performed and the criteria for PICO, PRISMA and risk of bias assessment were applied. Only clinical...
Fri Jul 03, 2020 03:00
Analyst, 2020, Accepted ManuscriptDOI: 10.1039/D0AN00269K, PaperQingqing Ding, Hui Chen, Chuanhui Huang, Qiaomei Lu, Ping Tong, Wenmin Zhang, Lan ZhangSorbents with high surface utilization and good dispersibility are of great importance for extraction performance of magnetic solid phase extraction (MSPE). In this study, a fish scale-like magnetic nanomaterial (Co@Co3O4/OCN)...The content of this RSS Feed (c) The Royal Society of Chemistry
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Analyst, 2020, Accepted ManuscriptDOI: 10.1039/D0AN00994F, MinireviewTianshu Chu, Jianlin Chu, Bingbing Gao, Bingfang HePaper chips have attracted great attention for their rapid development in multiple fields, such as life sciences, biochemistry, and materials. When manufacturing paper chips, flexible materials, such as cellulose paper...The content of this RSS Feed (c) The Royal Society of Chemistry
Fri Jul 03, 2020 02:00
Analyst, 2020, Accepted ManuscriptDOI: 10.1039/D0AN01111H, PaperFatih Ozefe, Ahu Arslan YildizThis work describes development of smartphone-assisted magnetic levitation assay for Point-of-Care (PoC) applications. Magnetic levitation is a technique that detects and separates particles based on their density differences in a...The content of this RSS Feed (c) The Royal Society of Chemistry
Fri Jul 03, 2020 02:00
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British Journal of Cancer, Published online: 06 July 2020; doi:10.1038/s41416-020-0947-yFirst results from five multidisciplinary diagnostic centre (MDC) projects for non-specific but concerning symptoms, possibly indicative of cancer
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British Journal of Cancer, Published online: 06 July 2020; doi:10.1038/s41416-020-0971-yMac-2-binding protein glycan isomer enhances the aggressiveness of hepatocellular carcinoma by activating mTOR signaling
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British Journal of Cancer, Published online: 06 July 2020; doi:10.1038/s41416-020-0958-8Vitamin D supplementation: a potential therapeutic agent for metastatic colorectal cancer
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British Journal of Cancer, Published online: 06 July 2020; doi:10.1038/s41416-020-0974-8Prognostic value of nucleotyping, DNA ploidy and stroma in high-risk stage II colon cancer
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British Journal of Cancer, Published online: 06 July 2020; doi:10.1038/s41416-020-0936-1Anticancer effects of the microbiota: how the microbiome shapes the development of IL-9-producing T cells
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British Journal of Cancer, Published online: 06 July 2020; doi:10.1038/s41416-020-0959-7Polygenic risk score opportunities for early detection and prevention strategies in endometrial cancer
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British Journal of Cancer, Published online: 06 July 2020; doi:10.1038/s41416-020-0964-xEvaluation of p16INK4a expression as a single marker to select patients with HPV-driven oropharyngeal cancers for treatment de-escalation
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2424 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: medical science These pubmed results were generated on 2020/07/05PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
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2424 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: medical science These pubmed results were generated on 2020/07/04PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Sat Jul 04, 2020 13:50
3125 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: medical science These pubmed results were generated on 2020/07/03PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Fri Jul 03, 2020 18:00
3125 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: medical science These pubmed results were generated on 2020/07/03PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Fri Jul 03, 2020 14:03
24 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: human homeostasis These pubmed results were generated on 2020/07/05PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
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24 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: human homeostasis These pubmed results were generated on 2020/07/04PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Sat Jul 04, 2020 16:41
40 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: human homeostasis These pubmed results were generated on 2020/07/03PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Fri Jul 03, 2020 16:21
Presbyphonia is an age-related voice disorder characterized by vocal fold atrophy and incomplete glottal closure during phonation. The extent to which the effects of presbyphonia may be compounded by age-related declines in the respiratory system and further impact communication and quality of life remains unknown. Therefore, the objective of this study was to determine how variations in respiratory function impacts voice measures in a sample of participants with presbyphonia.
Sun Jul 05, 2020 03:00
Vocal instructors during their normal workday are exposed to high noise levels that can affect their voice and hearing health. The goal of this study was to evaluate the voice and hearing status of voice instructors before and after lessons and relate these evaluations with voice and noise dosimetry taken during lessons.
Fri Jul 03, 2020 03:00
Publication date: Available online 4 July 2020Source: Journal of the American College of SurgeonsAuthor(s): Kota Nakamura, Masayuki Sho, Sohei Satoi, Hisashi Kosaka, Takahiro Akahori, Minako Nagai, Kenji Nakagawa, Tadataka Takagi, Tomohisa Yamamoto, So Yamaki
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Peer Assessment of Operative Videos with Sleeve Gastrectomy to Determine Optimal Operative Technique
Publication date: Available online 3 July 2020Source: Journal of the American College of SurgeonsAuthor(s): Oliver A. Varban, Jyothi R. Thumma, Arthur M. Carlin, Jonathan F. Finks, Amir A. Ghaferi, Justin B. Dimick
Sat Jul 04, 2020 15:59
Sarcomas are rare, malignant bone and soft-tissue tumours of mesenchymal origin, and their overall incidence accounts for 1% and 0.2%, respectively, of all malignancies. The aim of this article is to provide a reference on the evolving management concepts and trends of treatment of adult sarcomas of the head and neck in a major head and neck sarcoma centre. Early diagnosis remains a challenge due to non-specific symptomatology. Imaging such as ultrasound (US), magnetic resonance (MRI), computed tomography...
Sun Jul 05, 2020 03:00
We present the findings of our analysis of the funding and costs to provide facial laceration support within the Mid Yorkshire Hospitals NHS Trust Emergency Department (ED).
Sat Jul 04, 2020 03:00
Commercial aviation and medicine are sometimes compared, but in reality are diverse professions. What they share is the “human element” (in that whatever we do, we make mistakes on a regular basis). The understanding of several human factors (HF) that are common to both medicine and aviation, such as leadership, optimising communication, effective team work, stress, loss of individual and team situational awareness, fatigue, and lowering of authority gradients, are essential to minimise error.1–5
Sat Jul 04, 2020 03:00
Mandibular angle defect is considered to be one of the most important factors determining postoperative aesthetic outcome in mandibular reconstruction.1 However, when osseous lesions are localised in the mandibular angle, there is a dilemma in selecting optimal resection and bone reconstruction procedures, because there is no suitable reconstruction material for these lesions. If osseous or osteocutaneous flaps are used, a wide resection needs to be made because the bone defect is too small to apply...
Sat Jul 04, 2020 03:00
We report the case of a patient presenting with severe headache and progressive aphasia due to a large brain abscess. End-stage peri-implantitis on a dental implant in the upper jaw with contact to the maxillary sinus floor causing maxillary and frontal sinusitis could be identified as the source of infection. Multidisciplinary treatment included broad-spectrum antibiotics, craniotomy for abscess drainage, sinus surgery, and the removal of the implant. Despite all the care taken, the patient died,...
Sat Jul 04, 2020 03:00
The chin profile is an important factor that affects facial aesthetics. Despite the favourable results of alloplastic and allogenic materials used for vertical height augmentation genioplasty (VHAG), there is a risk of infection and graft rejection.1 An interpositional iliac bone graft can provide stable results but has donor-site morbidity.2
Sat Jul 04, 2020 03:00
Modification of the microscope drape to provide a closed surgical field in transoral robotic surgery
In transoral robotic surgery (TORS), the robot surgical assistant (RSA) is particularly at risk to airborne aerosols due to their role-determined position at the patient's mouth. Other than wearing adequate personal protective equipment (PPE), a physical barrier could further reduce the risk of aerosol-related transmission. Modifying the microscope drape to form a surgeon-patient barrier in TORS was explored. The aim was to place the patient within a completely sealed chamber, which can capture and...
Sat Jul 04, 2020 03:00
Need for randomised clinical trials on antibiotic treatment for odontogenic cervicofacial infections
Odontogenic cervicofacial infections are a worrying source of morbidity and mortality in dentistry.1,2
Sat Jul 04, 2020 03:00
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