Abstract Objective To compare the diagnostic performance of an artificial intelligence deep learning system with that of expert neuro‐ophthalmologists in classifying optic disc appearance. Methods The deep learning system was previously trained and validated on 14,341 ocular fundus photographs from 19 international centers. The performance of the system was evaluated on 800 new fundus photographs (400 normal optic discs, 201 papilledema [disc edema from elevated intracranial pressure],...
Fri Jul 03, 2020 21:34
Publication date: September 2020Source: Clinical Neurology and Neurosurgery, Volume 196Author(s): R. Demaerel, S. Klein, F. Van Calenbergh
Sun Jul 05, 2020 13:34
Publication date: September 2020Source: Clinical Neurology and Neurosurgery, Volume 196Author(s): Shivangi Singh, Raghav Govindarajan
Sun Jul 05, 2020 13:34
Publication date: September 2020Source: Clinical Neurology and Neurosurgery, Volume 196Author(s): Neha Gurha, Harmeet Singh Rehan, Madhur Yadav, Lalit Kumar Gupta
Sun Jul 05, 2020 13:34
Publication date: Available online 4 July 2020Source: Clinical Neurology and NeurosurgeryAuthor(s): Amarilis Giovino, Eileen Shomo, Kirsten Busey, Daniel Case, Alan Brockhurst, Mauricio Concha
Sun Jul 05, 2020 13:34
Publication date: September 2020Source: Clinical Neurology and Neurosurgery, Volume 196Author(s): Chafic Karam, Thomas Ragole, Orly Moshe-Lilie, Nizar Chahin
Fri Jul 03, 2020 18:57
Publication date: September 2020Source: Clinical Neurology and Neurosurgery, Volume 196Author(s): Ileok Jung, Ji Hye Shin, Jiyeon Kim
Fri Jul 03, 2020 18:57
Publication date: September 2020Source: Clinical Neurology and Neurosurgery, Volume 196Author(s): Turgay Cokyaman, Hakan Aylanc
Fri Jul 03, 2020 18:57
Publication date: September 2020Source: Clinical Neurology and Neurosurgery, Volume 196Author(s): Georgia Xiromerisiou, Stefania Kalampokini, Dimitrios Rikos, Antonios Provatas, Zisis Tsouris, Katerina Markou, Styliani Ralli, Efthimios Dardiotis
Fri Jul 03, 2020 18:57
Publication date: September 2020Source: Clinical Neurology and Neurosurgery, Volume 196Author(s): Abiodun M. Noah, Dalal Almghairbi, Iain K. Moppett
Fri Jul 03, 2020 18:57
Abstract The anterior insular cortex (AIC) has been implicated in addictive behaviour, including the loss of control over drug intake, craving and the propensity to relapse. Evidence suggests that the influence of the AIC on drug‐related behaviours is complex since in rats exposed to extended access to cocaine self‐administration, the AIC was shown to exert a state‐dependent, bidirectional influence on the development and expression of loss of control over drug intake, facilitating the latter but...
Fri Jul 03, 2020 18:58
Abstract Impulse control disorders (ICD) are characterized by generalized difficulty controlling emotions and behaviors. ICD are a broad group of the central nervous system (CNS) disorders including conduct disorder, intermittent explosive, oppositional‐defiant disorder, antisocial personality disorder, kleptomania, pyromania and other illnesses. Although they all share a common feature (aberrant impulsivity), their pathobiology is complex and poorly understood. There are also currently no ICD‐specific...
Fri Jul 03, 2020 18:56
Abstract Loss of nigrostriatal dopamine ( DA ) in Parkinson’s disease results in over‐activation/bursting of the subthalamic nucleus ( STN ). The STN projects to the substantia nigra ( SN ) pars compacta ( SNpc ) and pars reticulata ( SNpr ). The vesicular glutamate transporter 2 ( Vglut2 ) is localized within at least STN terminals synapsing within the SN, but it is not known if there are differential changes in the Vglut2+ input to the SNpc vs SNpr following...
Fri Jul 03, 2020 18:55
Abstract The “Choose a Movie‐CAM” is an established task to quantify the motivation for seeking social rewards. It allows participants to directly assess both the stimulus value and the effort required to obtain it. In the present study we aimed to identify the neural mechanisms of such cost‐benefit decision‐making. To this end, functional Magnetic Resonance Imaging (fMRI) data were collected from 24 typical adults while they completed the CAM task. We partly replicated the results from our previous...
Thu Jul 02, 2020 16:35
Recently, rehabilitation robots are expected to improve the gait of cerebral palsy (CP) children. However, only few previous studies have reported the kinematic and kinetic changes by using wearable exoskeleto...
Fri Jul 03, 2020 03:00
People use various strategies to maintain balance, such as taking a reactive step or rotating the upper body. To gain insight in human balance control, it is useful to know what makes people switch from one st...
Thu Jul 02, 2020 03:00
Statistical measures of motor, sensory and cognitive performance across repeated robot-based testing
Traditional clinical assessments are used extensively in neurology; however, they can be coarse, which can also make them insensitive to change. Kinarm is a robotic assessment system that has been used for pre...
Thu Jul 02, 2020 03:00
Generating appropriate balancing reactions in response to unexpected loss of balance during walking is important to prevent falls. The purpose of this study was to assess dynamic balancing responses following ...
Thu Jul 02, 2020 03:00
Publication date: Available online 3 July 2020Source: Journal of Neuroscience MethodsAuthor(s): Mohsin Mohammed, Jonas Thelin, Lina Gällentoft, Palmi Thor Thorbergsson, Lucas S. Kumosa, Jens Schouenborg, Lina M.E. Pettersson
Sat Jul 04, 2020 17:19
Publication date: Available online 2 July 2020Source: Journal of Neuroscience MethodsAuthor(s): P.A. Karthick, Kai Rui Wan, Angela See An Qi, Justin Dauwels, Nicolas Kon Kam King
Fri Jul 03, 2020 21:33
Abstract Objectives Phacomatoses are a group of neuro-oculo-cutaneous syndromes/ neurocutaneous disorders, involving structures arising from the embryonic ectoderm. Most of phacomatoses including the most common ones:, neurofibromatosis type I and type II (NF1, NF2) and tuberosclerosis complex (TSC), are autosomal dominant genetic disorders with full penetrance and variable expression. As no effective treatment exists, the only way...
Sun Jul 05, 2020 03:00
Abstract Background The cystic spinal dysraphism of the cervical and upper thoracic region (CDCT) accounts for only 3.9 to 8% of spina bifida cystica lesions. The presence of external cerebrospinal fluid (CSF) leakage is infrequent and very few authors have reported about surgical complications. Case report We present the case of a new born diagnosed...
Sat Jul 04, 2020 03:00
Fri Jul 03, 2020 03:00
Abstract Dysplastic gangliocytoma of the cerebellum (DGC), also called Lhermitte-Duclos disease, is a rare lesion of the posterior fossa consisting of a diffuse hypertrophy of the cerebellar cortex. DGC frequently presents in young adults and rarely in childhood. Only 3 cases have been previously described in newborns. We present an uncommon case of DGC which was diagnosed in utero. The radiological presentation prenatally and at birth was similar to a heterotopic neuroglial brain...
Fri Jul 03, 2020 03:00
Abstract Purpose This study aimed to comprehensively evaluate the diagnostic performance of dual-energy CT (DECT) for differentiating acute intracranial hemorrhage (ICH) from contrast staining or small calcifications via a systematic review and meta-analysis. Methods The PubMed–MEDLINE, EMBASE, and Cochrane Library databases were searched up to November...
Sat Jul 04, 2020 03:00
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