Abstract Purpose To evaluate the effects of denosumab (Dmb) on calcium, renal, and bone involvement in osteoporotic patients with primary hyperparathyroidism (PHPT) and compare with those who underwent a parathyroidectomy (PTX) procedure. Methods This retrospective, longitudinal study included patients treated with Dmb (60 mg) once every 6 months (n = 19)...
Fri Jul 03, 2020 03:00
Abstract Purpose Compared with newer prandial anti-diabetes agents, repaglinide and acarbose are unique in being globally available in generic versions, being oral, and being the cheapest of all. The aim of this study was to compare their efficacy when used alone or in combination. Methods In a randomized, double-blind, prospective study, 358 recently...
Fri Jul 03, 2020 03:00
Related Articles Effective doses of dental cone beam computed tomography: effect of 360-degree versus 180-degree rotation angles. Oral Surg Oral Med Oral Pathol Oral Radiol. 2020 Jun 29;: Authors: Mutalik S, Tadinada A, Molina MR, Sinisterra A, Lurie A Abstract OBJECTIVES: The aims of this study were to compare radiation absorbed dose (AD) and effective dose (ED) to tissues from cone beam computed tomography (CBCT) scans with 360-degree versus...
Sun Jul 05, 2020 23:24
Related Articles Development of the Jordanian Arabic early speech perception test. Int J Pediatr Otorhinolaryngol. 2020 May 25;136:110130 Authors: Alsabbagh N, Alaqrabawi W, Alsabbagh F, Kim Y, Jang H Abstract INTRODUCTION: The Early Speech Perception (ESP) test has been previously used to assess speech perception skills in young hearing-impaired children. As the Arabic language is known to be diglossic, the purpose of this study was to develop...
Sun Jul 05, 2020 23:26
Related Articles Safety and efficacy of T-DM1 in patients with advanced HER2-positive breast cancer The Royal Marsden experience. Cancer Treat Res Commun. 2020 Jun 27;24:100188 Authors: Battisti NMLL, Rogerson F, Lee K, Shepherd S, Mohammed K, Turner N, McGrath S, Okines A, Parton M, Johnston S, Allen M, Ring A Abstract BACKGROUND: Ado-trastuzumab emtansine (T-DM1) is standard of care for patients with advanced HER2+ breast cancer who relapse...
Sun Jul 05, 2020 23:29
Related Articles Association of triple positivity with prognostic parameters and overall survival in a population-based study of 6,122 HER2-positive breast cancer patients: analysis of real-world clinical practice based on a research database. Neoplasma. 2020 Jul 02;: Authors: Kolarova I, Vanasek J, Dolezel M, Stuk J, Hlavka A, Dusek L, Melichar B, Buchler T, Ryska A, Prausova J, Petrakova K, Tesarova P, Petera J, Vosmik M, Horackova K, Jarkovsky J Abstract...
Fri Jul 03, 2020 15:14
Related Articles Systemic Delivery of Aptamer Conjugated XBP1 siRNA Nanoparticle for Efficient Suppression of HER2+ Breast Cancer. ACS Appl Mater Interfaces. 2020 Jul 02;: Authors: Zhang L, Mu C, Zhang T, Wang Y, Wang Y, Fan L, Liu C, Chen H, Shen J, Wei K, Li H Abstract siRNA therapeutics as an emerging class of drug development is successfully coming to clinical utilization. RNA-based therapy is widely utilized to explore the mechanism and...
Fri Jul 03, 2020 15:14
Related Articles Analysis of the StoRM cohort reveals physical activity to be associated with survival in metastatic breast cancer. Sci Rep. 2020 Jul 01;10(1):10757 Authors: Delrieu L, Jacquet E, Segura-Ferlay C, Blanc E, Febvey-Combes O, Friedenreich C, Romieu G, Jacot W, Rios M, Heudel PE, Roemer-Becuwe C, Jouannaud C, Tredan O, Chaigneau L, Arnedos M, Orfeuvre H, Quenel-Tueux N, Jacquin JP, Ferrero JM, Moullet I, Abadie-Lacourtoisie S, Penault-Llorca F, Cox...
Fri Jul 03, 2020 15:14
Related Articles Sterile, abscess-like cerebral lesion during trastuzumab therapy after HER2 status switch in a triple negative breast cancer patient: a case report and literature review. BMC Cancer. 2020 Jul 01;20(1):615 Authors: Mezei T, Hajdu M, Czigléczki G, Lotz G, Kocsis J, Kulka J, Horváth A Abstract BACKGROUND: Breast cancer is a global health problem - it is the most common malignancy among women. Triple negative breast cancers (TNBC)...
Fri Jul 03, 2020 15:14
Related Articles Recent advances in orthognathic surgery. Curr Opin Otolaryngol Head Neck Surg. 2020 Aug;28(4):246-250 Authors: Jandali D, Barrera JE Abstract PURPOSE OF REVIEW: The aim of this article is to review the recent literature on orthognathic surgery for treatment of malocclusion and obstructive sleep apnea (OSA). The discussion outlines the refinements of the procedure and advances in technology. RECENT FINDINGS: Maxillomandibular...
Sat Jul 04, 2020 15:24
Related Articles The Sensor Technology and Rehabilitative Timing (START) Protocol: A Randomized Controlled Trial for the Rehabilitation of Mild Traumatic Brain Injury. Phys Ther. 2020 04 17;100(4):687-697 Authors: Parrington L, Jehu DA, Fino PC, Stuart S, Wilhelm J, Pettigrew N, Murchison CF, El-Gohary M, VanDerwalker J, Pearson S, Hullar T, Chesnutt JC, Peterka RJ, Horak FB, King LA Abstract BACKGROUND: Clinical practice for rehabilitation...
Sat Jul 04, 2020 15:24
Related Articles Immune related proteins and tumor infiltrating CD8+ lymphocytes in hypopharyngeal cancer in relation to human papillomavirus (HPV) and clinical outcome. Head Neck. 2020 Jul 01;: Authors: Landin D, Ährlund-Richter A, Mirzaie L, Mints M, Näsman A, Kolev A, Marklund L, Dalianis T, Munck-Wikland E, Ramqvist T Abstract BACKGROUND: Hypopharyngeal cancer (HPSCC) shows a poor clinical outcome, while HPSCC, caused by human papillomavirus...
Fri Jul 03, 2020 15:48
Related Articles The impact of clinicopathological factors on clinical outcomes in patients with salivary gland adenoid cystic carcinoma: a multi-institutional analysis in Japan. Int J Clin Oncol. 2020 Jul 01;: Authors: Kawakita D, Murase T, Ueda K, Kano S, Tada Y, Tsukahara K, Okami K, Onitsuka T, Fujimoto Y, Matoba T, Sakurai K, Nagao T, Hanai N, Kawata R, Hato N, Nibu KI, Urano M, Taguchi KI, Nakaguro M, Kusafuka K, Yamamoto H, Nagao T, Inagaki H ...
Fri Jul 03, 2020 15:48
Related Articles Allergen Immunotherapy (AIT) in children: a vulnerable population with its own rights and legislation - summary of EMA-initiated multi-stakeholder meeting on Allergen Immunotherapy (AIT) for children, held at Paul-Ehrlich-Institut, Langen, Germany, 16.1.2019. Clin Transl Allergy. 2020;10:28 Authors: Mahler V, Mentzer D, Bonertz A, Muraro A, Eigenmann P, Bousquet J, Halken S, Pfaar O, Jutel M, Wahn U, Vieths S, Kaul S Abstract ...
Fri Jul 03, 2020 15:48
Related Articles Cotargeting CHK1 and PI3K Synergistically Suppresses Tumor Growth of Oral Cavity Squamous Cell Carcinoma in Patient-Derived Xenografts. Cancers (Basel). 2020 Jun 29;12(7): Authors: Yang CY, Liu CR, Chang IY, OuYang CN, Hsieh CH, Huang YL, Wang CI, Jan FW, Wang WL, Tsai TL, Liu H, Tseng CP, Chang YS, Wu CC, Chang KP Abstract Oral cavity squamous cell carcinomas (OSCCs) are aggressive tumors, and their recurrence leads to poor...
Fri Jul 03, 2020 15:48
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