Κυριακή 5 Ιουλίου 2020


Can four-dimensional computed tomography support diagnosis and treatment planning?: a case report before and after coronoidectomy
Abstract Introduction Elongated mandibular coronoid process is a rare condition defined as enlargement of the coronoid process. The only useful way to treat the mouth-opening limitation is resection of the elongated coronoid process. Four-dimensional CT (4DCT; three spatial dimensions plus time axis) is a novel imaging technique. Its usefulness of for evaluation of dynamic movements such as joint motion has been reported. Here, we show...
Oral and Maxillofacial Surgery
Fri Jul 03, 2020 03:00
High-throughput nucleotide sequencing for bacteriome studies in oral squamous cell carcinoma: a systematic review
Abstract Purpose Dysbiosis has been identified in oral squamous cell carcinoma (OSCC). The aim of this study was to carry out a systematic review of an electronic research that was carried out on articles published between January 2008 and September 2018. Methods Eight studies were selected after applying the inclusion and exclusion criteria. ...
Oral and Maxillofacial Surgery
Fri Jul 03, 2020 03:00
The Pneumococcal Polysaccharide-Tetanus Toxin Native C-Fragment Conjugate Vaccine: The Carrier Effect and Immunogenicity
The encapsulated bacteria, as Streptococcus pneumonia, Haemophilus influenzae type b, and Neisseria meningitidis, cause serious morbidity and mortality worldwide. The capsular polysaccharide (PS), which could elicit a weak T cell-independent immune response, is a vital virulence determinant. One of the strategies to improve the PS-specific immunogenicity is to conjugate PS with a nontoxic carrier protein. Tetanus toxoid (TT) and CRM197 are the typical carrier proteins for the PS conjugate vaccines....
Mediators of Inflammation
Sat Jul 04, 2020 15:05
Anti-Inflammatory Effect of a Peptide Derived from the Synbiotics, Fermented Cudrania tricuspidata with Lactobacillus gasseri, on Inflammatory Bowel Disease
The objective of this study was to evaluate the effects of peptides derived from synbiotics on improving inflammatory bowel disease (IBD). Five-week-old male C57BL/6 mice were administered with dextran sulfate sodium (DSS) via drinking water for seven days to induce IBD (IBD group). The mice in the IBD group were orally administered with PBS (IBD-PBS-positive control), Lactobacillus gasseri 505 (IBD-Pro), fermented powder of CT extract with L. gasseri 505 (IBD-Syn), β-casein: LSQSKVLPVPQKAVPYPQRDMP...
Mediators of Inflammation
Sat Jul 04, 2020 15:05
Inhibition of A2B Adenosine Receptor Attenuates Intestinal Injury in a Rat Model of Necrotizing Enterocolitis
Necrotizing enterocolitis (NEC) is a lethal gastrointestinal tract disease that occurs in premature infants. Adenosine receptor A2B (A2BR) regulates the inflammation cytokine secretion and immune cell infiltration in the colonic pathophysiology conditions. In the present study, we aim to determine the roles of A2BR in the development of NEC. A NEC rat model was established and treated with A2BR agonist-BAY60-6583 or A2BR antagonist-PSB1115. Animals in the control group were free from any interventions....
Mediators of Inflammation
Fri Jul 03, 2020 17:20
Extrahepatic metabolism of ibrutinib
Summary Ibrutinib is a first-in-class Bruton’s kinase inhibitor used in the treatment of multiple lymphomas. In addition to CYP3A4-mediated metabolism, glutathione conjugation can be observed. Subsequently, metabolism of the conjugates and finally their excretion in feces and urine occurs. These metabolites, however, can reach substantial concentrations in human subjects, especially when CYP3A4 is inhibited. Ibrutinib has unexplained nephrotoxicity and high metabolite concentrations...
Latest Results for Investigational New Drugs
Sat Jul 04, 2020 03:00
Complementary Health Approaches for People With Parkinson Disease
Publication date: Available online 3 July 2020Source: Archives of Physical Medicine and RehabilitationAuthor(s): Sanghee Moon, Caio V.M. Sarmento, Yvonne Colgrove, Wen Liu
Archives of Physical Medicine and Rehabilitation
Sat Jul 04, 2020 22:22
Analysis of the Microbiota of the Physiotherapist's Environment
Publication date: Available online 2 July 2020Source: Archives of Physical Medicine and RehabilitationAuthor(s): Tomás Pérez-Fernández., Francisco Llinares-Pinel., Mayte Troya-Franco., Luis Fernández-Rosa.
Archives of Physical Medicine and Rehabilitation
Fri Jul 03, 2020 14:13
Alternative Approaches to Adenotonsillectomy and Continuous Positive Airway Pressure (CPAP) for the Management of Pediatric Obstructive Sleep Apnea (OSA): A Review
Continuous positive airway pressure (CPAP) is considered first-line treatment in the management of pediatric patients without a surgically correctible cause of obstruction who have confirmed moderate-to-severe obstructive sleep apnea (OSA). The evidence supports its reduction on patient morbidity and positive influence on neurobehavioral outcome. Unfortunately, in clinical practice, many patients either refuse CPAP or cannot tolerate it. An update on alternative approaches to CPAP for the management...
Sleep Disorders
Sat Jul 04, 2020 07:50
Translating Dysphagia Evidence into Practice While Avoiding Pitfalls: Assessing Bias Risk in Tracheostomy Literature
Abstract Critically ill patients who require a tracheostomy often have dysphagia. Widespread practice guidelines have yet to be developed regarding the acute assessment and management of dysphagia in patients with tracheostomy. In order for clinicians to base their practice on the best available evidence, they must first assess the applicable literature and determine its quality. To inform guideline development, our objective was to assess literature quality concerning swallowing...
Dysphagia
Sat Jul 04, 2020 03:00
Modeling and imaging of intestinal electrical impedance based on conjugate gradient method
Abstract Colorectal disease is a digestive tract disease of high incidence worldwide. Its preliminary diagnosis methods such as anal digital diagnosis and enteroscopy are somewhat subjective. Moreover, it is difficult to locate precisely the lesions and their infiltration boundaries for an accurate diagnosis of disease. This study combines endoscope with electrodes placed on the inner wall of the intestine to obtain both the traditional image of the intestine lumen and its electrical impedance tomography...
International Journal for Numerical Methods in Biomedical Engineering
Sat Jul 04, 2020 18:36
High Precision Invasive FFR, Low‐Cost Invasive iFR, Or Non‐Invasive CFR?: Optimum Assessment of Coronary Artery Stenosis Based on the Patient‐Specific Computational Models
Abstract The objective of this paper is to apply computational fluid dynamic (CFD) as a complementary tool for clinical tests to not only predict the present and future status of left coronary artery stenosis but also to evaluate some clinical hypotheses. In order to assess the present status of the coronary artery stenosis severity, and thereby, selecting the most appropriate type of treatment for each patient, fractional flow reserve (FFR), instantaneous wave free‐ratio (iFR), and coronary flow...
International Journal for Numerical Methods in Biomedical Engineering
Sat Jul 04, 2020 18:34
BRAF inhibition in melanoma is associated with the dysregulation of histone methylation and histone methyltransferases
Publication date: September 2020Source: Neoplasia, Volume 22, Issue 9Author(s): Florina Grigore, Hana Yang, Nicholas D. Hanson, Matthew W. VanBrocklin, Aaron L. Sarver, James P. Robinson
Neoplasia
Sat Jul 04, 2020 19:53
Dual inhibition of VEGF and PARP suppresses KRAS-mutant colorectal cancer
Publication date: September 2020Source: Neoplasia, Volume 22, Issue 9Author(s): Longhui Zhong, Rong Wang, Yanxia Wang, Shunli Peng, Yueyun Ma, Sijie Ding, Hong Yang, Shiyu Chen, Xiaoqing Luo, Wei Wang
Neoplasia
Sat Jul 04, 2020 19:53
TROY signals through JAK1-STAT3 to promote glioblastoma cell migration and resistance
Publication date: September 2020Source: Neoplasia, Volume 22, Issue 9Author(s): Zonghui Ding, Jean M. Kloss, Serdar Tuncali, Nhan L. Tran, Joseph C. Loftus
Neoplasia
Sat Jul 04, 2020 19:53
Cloning and promoter analysis of palladin 90-kDa, 140-kDa, and 200-kDa isoforms involved in skeletal muscle cell maturation
Palladin is a ubiquitous phosphoprotein expressed in vertebrate cells that works as a scaffolding protein. Several isoforms deriving from alternative splicing are originated from the palladin gene and involved...
BMC Research Notes
Fri Jul 03, 2020 03:00
Whole genome sequence of five strains of Spiroplasma citri isolated from different host plants and its leafhopper vector
Spiroplasma citri is a bacterium with a wide host range and is the causal agent of citrus stubborn and brittle root diseases of citrus and horseradish, respectively. S. citri is transmitted in a circulative, pers...
BMC Research Notes
Fri Jul 03, 2020 03:00
Dissociable pathways for moving and static face perceptionbegin in early visual cortex: evidence from an acquired prosopagnosic
Publication date: Available online 3 July 2020Source: CortexAuthor(s): Magdalena W. Sliwinska, Caitlin Bearpark, Julia Corkhill, Aimee McPhillips, David Pitcher
Cortex
Sat Jul 04, 2020 17:59
The black box of global aphasia: neuroanatomical underpinnings of remission from acute global aphasia with preserved inner language function
Publication date: Available online 3 July 2020Source: CortexAuthor(s): Joanna Sierpowska, Patricia León-Cabrera, Àngels Camins, Montserrat Juncadella, Andreu Gabarrós, Antoni Rodríguez-Fornells
Cortex
Fri Jul 03, 2020 16:00
Intrinsic Laryngeal Lipoma Treated with Transoral CO₂ Laser Microsurgery: An Unusual Case Report.
Related Articles Intrinsic Laryngeal Lipoma Treated with Transoral CO₂ Laser Microsurgery: An Unusual Case Report. Am J Case Rep. 2020 Jul 03;21:e920528 Authors: Lombardo N, Lobello N, Piazzetta G, Ciriolo M, Pelaia C, Testa D, Motta G Abstract BACKGROUND Lipomas, the most common soft tissue tumors, represent almost half of all benign mesenchymal neoplasms and are characterized by the absence of symptoms. However, if they grow in a laryngeal...
Vocal Fold Polyps
Sat Jul 04, 2020 17:37
Speech-Language Pathologists and Prosody: Clinical Practices and Barriers
Publication date: Available online 3 July 2020Source: Journal of Communication DisordersAuthor(s): Kara Hawthorne, Sarah Fischer
Journal of Communication Disorders (open access)
Sat Jul 04, 2020 16:42
Linguistic and auditory processing skills in non-syndromic children with cleft palate: a scoping review
Publication date: Available online 3 July 2020Source: Journal of Communication DisordersAuthor(s): Stephanie van Eeden, Helen Stringer
Journal of Communication Disorders (open access)
Sat Jul 04, 2020 16:42
Real time comprehension of Spanish articles in children with Developmental Language Disorder: empirical evidence from eye movements
Publication date: Available online 3 July 2020Source: Journal of Communication DisordersAuthor(s): Spyros Christou, Ernesto Guerra, Carmen Julia Coloma, Llorenç Andreu Barrachina, Claudia Araya, Javier Rodriguez-Ferreiro, Maria Jose Buj Pereda, Monica Sanz-Torrent
Journal of Communication Disorders (open access)
Sat Jul 04, 2020 16:42
Parental perceptions and expectations concerning speech therapy-related cleft care – a qualitative study
Publication date: Available online 3 July 2020Source: Journal of Communication DisordersAuthor(s): Cassandra Alighieri, Wim Peersman, Kim Bettens, Vienna Van Herreweghe, Kristiane Van Lierde
Journal of Communication Disorders (open access)
Sat Jul 04, 2020 16:42
Using AAC to Unlock Communicative Potential in Late-Talking Toddlers
Publication date: Available online 3 July 2020Source: Journal of Communication DisordersAuthor(s): Isabel I. Navarro, Sarah R. Cretcher, Angelica R. McCarron, Cecilia Figueroa, Mary Alt
Journal of Communication Disorders (open access)
Fri Jul 03, 2020 12:48
SARS-CoV-2 infection in a psoriatic arthritis patient treated with IL-17 inhibitor
Publication date: November 2020Source: Medical Hypotheses, Volume 144Author(s): Rosario Foti, Giorgio Amato, Visalli Elisa
ScienceDirect Publication: Medical Hypotheses
Sat Jul 04, 2020 16:41
Can atypical dysgeusia in depression be related to a deafferentation syndrome?
Publication date: November 2020Source: Medical Hypotheses, Volume 144Author(s): Rami Bou Khalil, Elie Atallah, Elina Dirani, Maya Kallab, Anthony Kassab, Marc Mourad, Rhéa El Khoury
ScienceDirect Publication: Medical Hypotheses
Sat Jul 04, 2020 16:41
The neuropathological basis of anxiety in Parkinson’s disease
Publication date: November 2020Source: Medical Hypotheses, Volume 144Author(s): Paul G. Overton, Veronique Coizet
ScienceDirect Publication: Medical Hypotheses
Sat Jul 04, 2020 16:41
Cross-immunity between respiratory coronaviruses may limit COVID-19 fatalities
Publication date: November 2020Source: Medical Hypotheses, Volume 144Author(s): Ahmed Yaqinuddin
ScienceDirect Publication: Medical Hypotheses
Sat Jul 04, 2020 16:41
Proposed hypothesis and rationale for association between mastitis and breast cancer
Publication date: November 2020Source: Medical Hypotheses, Volume 144Author(s): Joanne Nolan, Suzanne S. Dunne, Wed Mustafa, Laxsanaa Sivananthan, Patrick A. Kiely, Colum P. Dunne
ScienceDirect Publication: Medical Hypotheses
Sat Jul 04, 2020 16:41
Central nervous system lymphoma and radiofrequency radiation – A case report and incidence data in the Swedish Cancer Register on non-Hodgkin lymphoma
Publication date: November 2020Source: Medical Hypotheses, Volume 144Author(s): Lennart Hardell, Michael Carlberg, Tarmo Koppel, Marie Nordström, Lena K. Hedendahl
ScienceDirect Publication: Medical Hypotheses
Sat Jul 04, 2020 16:41
Rethinking carcinogenesis: The detached pericyte hypothesis
Publication date: November 2020Source: Medical Hypotheses, Volume 144Author(s): Stuart G. Baker
ScienceDirect Publication: Medical Hypotheses
Sat Jul 04, 2020 16:41
Law and mental health: A bridge between individual neurobiology and the collective organization of behaviors
Publication date: November 2020Source: Medical Hypotheses, Volume 144Author(s): Emanuele Perrone, Francesco De Bei, Gianmarco Cristofari
ScienceDirect Publication: Medical Hypotheses
Sat Jul 04, 2020 16:41
COVID-19 as a viral functional ACE2 deficiency disorder with ACE2 related multi-organ disease
Publication date: November 2020Source: Medical Hypotheses, Volume 144Author(s): Rosemary Gan, Nicholas P. Rosoman, David J.E. Henshaw, Euan P. Noble, Peter Georgius, Nigel Sommerfeld
ScienceDirect Publication: Medical Hypotheses
Fri Jul 03, 2020 19:56
COVID-19: NAD<sup>+</sup> deficiency may predispose the aged, obese and type2 diabetics to mortality through its effect on SIRT1 activity
Publication date: November 2020Source: Medical Hypotheses, Volume 144Author(s): R. Miller, A.R. Wentzel, G.A. Richards
ScienceDirect Publication: Medical Hypotheses
Fri Jul 03, 2020 19:56
Can volcanic trace elements facilitate Covid-19 diffusion? A hypothesis stemming from the Mount Etna area, Sicily
Publication date: November 2020Source: Medical Hypotheses, Volume 144Author(s): Loredana Raciti, Rocco Salvatore Calabrò
ScienceDirect Publication: Medical Hypotheses
Fri Jul 03, 2020 19:56
Why the lower reported prevalence of asthma in patients diagnosed with COVID-19 validates repurposing EDTA solutions to prevent and manage treat COVID-19 disease
Publication date: November 2020Source: Medical Hypotheses, Volume 144Author(s): Daniel P. Cashman
ScienceDirect Publication: Medical Hypotheses
Fri Jul 03, 2020 19:56
Primary squamous cell carcinoma of the parotid gland: clinicopathological characteristics, treatment, and prognosis
Publication date: Available online 4 July 2020Source: International Journal of Oral and Maxillofacial SurgeryAuthor(s): M. Xiao, J. Liu, Y. You, X. Yang, Y. Wang
Oral and Maxillofacial Surgery
Sat Jul 04, 2020 16:38
Editorial Board/Reviewing Committee
Publication date: July 2020Source: International Journal of Oral and Maxillofacial Surgery, Volume 49, Issue 7Author(s):
Oral and Maxillofacial Surgery
Sat Jul 04, 2020 16:38

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