Pathogens, Vol. 9, Pages 536: Inactivation of Scrapie Prions by the Electrically Charged Disinfectant CAC-717 Pathogens doi: 10.3390/pathogens9070536 Authors: Akikazu Sakudo Yoshifumi Iwamaru Koichi Furusaki Makoto Haritani Rumiko Onishi Morikazu Imamura Takashi Yokoyama Yasuhiro Yoshikawa Takashi Onodera Previous studies have revealed that the electrically charged disinfectant CAC-717 has strong virucidal and bactericidal effects but is safe for humans and animals....
Pathogens, Vol. 9, Pages 535: Evaluation of Interferon-Gamma Polymorphisms as a Risk Factor in Feline Infectious Peritonitis Development in Non-Pedigree Cats—A Large Cohort Study Pathogens doi: 10.3390/pathogens9070535 Authors: Emi N. Barker Philippa Lait Lorenzo Ressel Emily-Jayne Blackwell Séverine Tasker Helen Kedward-Dixon Anja Kipar Christopher R. Helps Feline infectious peritonitis (FIP) is a common infectious cause of death in cats, with heritable host factors...
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Pharmaceutics, Vol. 12, Pages 627: Probing the DNA Reactivity and the Anticancer Properties of a Novel Tubercidin-Pt(II) Complex Pharmaceutics doi: 10.3390/pharmaceutics12070627 Authors: Stefano D’Errico Andrea Patrizia Falanga Domenica Capasso Sonia Di Gaetano Maria Marzano Monica Terracciano Giovanni Nicola Roviello Gennaro Piccialli Giorgia Oliviero Nicola Borbone Herein, we reported on the synthesis of a novel Pt(II) neutral complex having as ligand the...
Pharmaceutics, Vol. 12, Pages 629: Ophthalmic In Situ Gelling System Containing Lanosterol Nanoparticles Delays Collapse of Lens Structure in Shumiya Cataract Rats Pharmaceutics doi: 10.3390/pharmaceutics12070629 Authors: Nagai Umachi Otake Oka Hiramatsu Sasaki Yamamoto We attempted to prepare ophthalmic in situ gel formulations containing lanosterol (Lan) nanoparticles (LA-NPs/ISG) and investigated the characteristics, delivery pathway into the lens, and anti-cataract...
Pharmaceutics, Vol. 12, Pages 625: Unraveling Particle Formation: From Single Droplet Drying to Spray Drying and Electrospraying Pharmaceutics doi: 10.3390/pharmaceutics12070625 Authors: Boel Koekoekx Dedroog Babkin Vetrano Clasen Van den Mooter Spray drying and electrospraying are well-established drying processes that already have proven their value in the pharmaceutical field. However, there is currently still a lack of knowledge on the fundamentals of the...
Pharmaceutics, Vol. 12, Pages 628: Development of New Formula Microcapsules from Nutmeg Essential Oil Using Sucrose Esters and Magnesium Aluminometasilicate Pharmaceutics doi: 10.3390/pharmaceutics12070628 Authors: Matulyte Kasparaviciene Bernatoniene Essential oils are volatile liquids which evaporate and lose their pharmacological effect when exposed to the environment. The aim of this study is to protect nutmeg essential oil from environmental factors by encapsulation (shell...
Pharmaceutics, Vol. 12, Pages 626: Assessment of Residual Solvent and Drug in PLGA Microspheres by Derivative Thermogravimetry Pharmaceutics doi: 10.3390/pharmaceutics12070626 Authors: Shim Sah Thermogravimetry does not give specific information on residual organic solvents in polymeric matrices unless it is hyphenated with the so-called evolved gas analysis. The purpose of this study was to apply, for the first time, derivative thermogravimetry (DTG) to characterize a residual...
Pharmaceutics, Vol. 12, Pages 624: Postbiotic-Enabled Targeting of the Host-Microbiota-Pathogen Interface: Hints of Antibiotic Decline? Pharmaceutics doi: 10.3390/pharmaceutics12070624 Authors: Puccetti Xiroudaki Ricci Giovagnoli Mismanagement of bacterial infection therapies has undermined the reliability and efficacy of antibiotic treatments, producing a profound crisis of the antibiotic drug market. It is by now clear that tackling deadly infections demands novel strategies...
Pharmaceutics, Vol. 12, Pages 630: Stimuli-Responsive Nanomaterials for Application in Antitumor Therapy and Drug Delivery Pharmaceutics doi: 10.3390/pharmaceutics12070630 Authors: Pham Choi Choi The new era of nanotechnology has produced advanced nanomaterials applicable to various fields of medicine, including diagnostic bio-imaging, chemotherapy, targeted drug delivery, and biosensors. Various materials are formed into nanoparticles, such as gold nanomaterials, carbon quantum...
Pharmaceutics, Vol. 12, Pages 623: Erratum: Sun, X.; et al. Folic Acid and PEI Modified Mesoporous Silica for Targeted Delivery of Curcumin. Pharmaceutics, 2019, 11, 430 Pharmaceutics doi: 10.3390/pharmaceutics12070623 Authors: Xiaoxiao Sun Nan Wang Li-Ye Yang Xiao-Kun Ouyang Fangfang Huang The authors wish to make the following corrections to this paper [1]: [...]
Pharmaceutics, Vol. 12, Pages 622: Controlled Release of Doxorubicin from the Drug Delivery Formulation Composed of Single-Walled Carbon Nanotubes and Congo Red: A Molecular Dynamics Study and Dynamic Light Scattering Analysis Pharmaceutics doi: 10.3390/pharmaceutics12070622 Authors: Anna Jagusiak Katarzyna Chlopas Grzegorz Zemanek Pawel Wolski Tomasz Panczyk The controlled delivery and release of drug molecules at specific targets increases the therapeutic efficacy of treatment....
Pharmaceutics, Vol. 12, Pages 621: Tumor-Targeting Glycol Chitosan Nanoparticles for Image-Guided Surgery of Rabbit Orthotopic VX2 Lung Cancer Pharmaceutics doi: 10.3390/pharmaceutics12070621 Authors: Kyeong Cheol On Jiyun Rho Hong Yeol Yoon Hyeyoun Chang Ji Young Yhee Jun Sik Yoon Seo Young Jeong Hyun Koo Kim Kwangmeyung Kim Theranostic nanoparticles can deliver therapeutic agents as well as diverse imaging agents to tumors. The enhanced permeation and retention...
Pharmaceutics, Vol. 12, Pages 620: 3D Printed Drug Delivery Systems Based on Natural Products Pharmaceutics doi: 10.3390/pharmaceutics12070620 Authors: Ángela Aguilar-de-Leyva Vicente Linares Marta Casas Isidoro Caraballo In the last few years, the employment of 3D printing technologies in the manufacture of drug delivery systems has increased, due to the advantages that they offer for personalized medicine. Thus, the possibility of producing sophisticated and tailor-made structures...
Pharmaceutics, Vol. 12, Pages 619: A Mixed-Surface Polyamidoamine Dendrimer for In Vitro and In Vivo Delivery of Large Plasmids Pharmaceutics doi: 10.3390/pharmaceutics12070619 Authors: Bhairavi Srinageshwar Maria Florendo Brittany Clark Kayla Johnson Nikolas Munro Sarah Peruzzaro Aaron Antcliff Melissa Andrews Alexander Figacz Douglas Swanson Gary L. Dunbar Ajit Sharma Julien Rossignol Drug delivery to the brain is highly hindered by the presence...
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Plants, Vol. 9, Pages 846: Quantifying Metal Contamination and Potential Uptake by Phragmites australis Adans. (Poaceae) Along a Subtropical River System Plants doi: 10.3390/plants9070846 Authors: Netshiongolwe Cuthbert Maenetje Chari Motitsoe Wasserman Munyai Dalu : Metal pollution is pervasive across terrestrial and aquatic ecosystems owing to anthropogenic activities. Sediments can accrue high concentrations of metals and act as secondary sources, and...
Plants, Vol. 9, Pages 847: Transcriptome Sequencing and Chemical Analysis Reveal the Formation Mechanism of White Florets in Carthamus tinctorius L. Plants doi: 10.3390/plants9070847 Authors: Tingyan Qiang Jiushi Liu Yuqing Dong Yinbo Ma Bengang Zhang Xueping Wei Haitao Liu Peigen Xiao Carthamus tinctorius L. (safflower), an economic crop and herb, has been extensively studied for its diverse chemical constituents and pharmacological effects, but the mechanism of...
Plants, Vol. 9, Pages 843: Cytogenetic Study on the Biostimulation Potential of the Aqueous Fruit Extract of Hippophae rhamnoides for a Sustainable Agricultural Ecosystem Plants doi: 10.3390/plants9070843 Authors: Elena Bonciu Aurel Liviu Olaru Elena Rosculete Catalin Aurelian Rosculete This cytogenetic study evaluates the biostimulation potential of the aqueous extract of seabuckthorn fruits (AESF) in plant cells, using the Allium cepa species as a test plant. The effects were...
Plants, Vol. 9, Pages 844: Large-Scale Plant Production of Lycium barbarum L. by Liquid Culture in Temporary Immersion System and Possible Application to the Synthesis of Bioactive Substance Plants doi: 10.3390/plants9070844 Authors: Claudia Ruta Giuseppe De Mastro Simona Ancona Anna Tagarelli Francesca De Cillis Carla Benelli Maurizio Lambardi Goji (Lycium barbarum L.) has recognized nutritive and antioxidant properties and many products are commercialized for health...
Plants, Vol. 9, Pages 845: Leaf Lipid Alterations in Response to Heat Stress of Arabidopsis thaliana
Plants, Vol. 9, Pages 845: Leaf Lipid Alterations in Response to Heat Stress of Arabidopsis thaliana Plants doi: 10.3390/plants9070845 Authors: Sunitha Shiva Thilani Samarakoon Kaleb A. Lowe Charles Roach Hieu Sy Vu Madeline Colter Hollie Porras Caroline Hwang Mary R. Roth Pamela Tamura Maoyin Li Kathrin Schrick Jyoti Shah Xuemin Wang Haiyan Wang Ruth Welti In response to elevated temperatures, plants alter the activities of enzymes that affect...
Plants, Vol. 9, Pages 842: Plant Molecular Farming: A Viable Platform for Recombinant Biopharmaceutical Production Plants doi: 10.3390/plants9070842 Authors: Balamurugan Shanmugaraj Christine Joy I. Bulaon Waranyoo Phoolcharoen The demand for recombinant proteins in terms of quality, quantity, and diversity is increasing steadily, which is attracting global attention for the development of new recombinant protein production technologies and the engineering of conventional established...
Plants, Vol. 9, Pages 841: Changes in the Phenolic Compounds of Hop (Humulus lupulus L.) Induced by Infection with Verticillium nonalfalfae, the Causal Agent of Hop Verticillium Wilt Plants doi: 10.3390/plants9070841 Authors: Urban Kunej Maja Mikulič-Petkovšek Sebastjan Radišek Nataša Štajner Phenolic compounds are involved in plant responses to various biotic and abiotic stress factors, with many studies suggesting their role in defense mechanisms against fungal pathogens....
Plants, Vol. 9, Pages 838: Antimicrobial Effects against Oral Pathogens and Cytotoxicity of Glycyrrhiza uralensis Extract Plants doi: 10.3390/plants9070838 Authors: Song-Yi Yang Yu-Ri Choi Myung-Jin Lee Min-Kyung Kang We aimed to evaluate the antimicrobial effects of Glycyrrhiza uralensis extract on Streptococcus mutans and Candida albicans and its biocompatibility for dental applications. The antimicrobial activity of the G. uralensis extracts at concentrations of 50, 100,...
Plants, Vol. 9, Pages 839: Nematicidal Efficacy of Milbemectin against Root-Knot Nematodes Plants doi: 10.3390/plants9070839 Authors: Miguel Talavera-Rubia Maria Dolores Vela-Delgado Soledad Verdejo-Lucas The nematicidal efficacy of milbemectin and its commercial formulate Milbeknock® on (i) egg hatching, (ii) juvenile motility and (iii) infective capacity of root-knot nematodes was evaluated in vitro and in planta assays. Serial dilutions of pure milbemectin were tested...
Plants, Vol. 9, Pages 837: Exogenous Carbon Compounds Modulate Tomato Root Development Plants doi: 10.3390/plants9070837 Authors: Ana Isabel González-Hernández Loredana Scalschi Pilar García-Agustín Gemma Camañes NO3− is not only a nutrient, but also a signaling compound that plays an important role in several plant processes, like root development. The present study aimed to investigate the effect of three different exogenous C compounds (sucrose, glucose, 2-oxoglutarate)...
Plants, Vol. 9, Pages 840: Knock-Down the Expression of Brassinosteroid Receptor TaBRI1 Reduces Photosynthesis, Tolerance to High Light and High Temperature Stresses and Grain Yield in Wheat Plants doi: 10.3390/plants9070840 Authors: Jingjing Fang Weiqi Zhu Yiping Tong Brassinosteroid (BR)-deficient or -insensitive mutants exhibited altered plant architecture with the potential to impact yield, the underlying physiological and molecular mechanisms are still to be explored. In this...
Plants, Vol. 9, Pages 836: QTL Mapping and Prediction of Haploid Male Fertility Traits in Maize (Zea mays L.) Plants doi: 10.3390/plants9070836 Authors: Yanyan Jiao Jinlong Li Wei Li Ming Chen Mengran Li Wenxin Liu Chenxu Liu Shaojiang Chen Chromosome doubling of maize haploids is a bottleneck in the large-scale application of doubled haploid (DH) technology. Spontaneous chromosome doubling (SCD) of haploid has been taken as an important method in the production...
Plants, Vol. 9, Pages 835: Two New Putative Plant Viruses from Wood Metagenomics Analysis of an Esca Diseased Vineyard Plants doi: 10.3390/plants9070835 Authors: Nadia Bertazzon Walter Chitarra Elisa Angelini Luca Nerva The concept of plant as a holobiont is now spreading among the scientific community and the importance to study plant-associated microorganisms is becoming more and more necessary. Along with bacteria and fungi, also viruses can play important roles during the...
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Prosthesis, Vol. 2, Pages 153-169: A Systematic Review of the Effectiveness of Cell-Based Therapy in Repairing Peripheral Nerve Gap Defects Prosthesis doi: 10.3390/prosthesis2030014 Authors: Sahar Barton Tansley Nerve prostheses are widely utilized to reconstruct segmental (gap) defects in peripheral nerves as an alternative to nerve grafting. However, with increasing gap length, the effectiveness of a nerve prosthesis becomes sub-optimal, which subsequently has made repairing...
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Psych, Vol. 2, Pages 153-154: Psych: An International, Open Access, Peer Reviewed Journal on Fields Ranging from Experimental Psychology to Clinical Psychiatry Psych doi: 10.3390/psych2030013 Authors: Thomas E. Schläpfer It is with great honour and pleasure that I introduce, on behalf of the four Section Editors-in-Chief, the 53 members of the editorial board and the publisher MDPI, this journal [...]
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Religions, Vol. 11, Pages 333: A Review of Spiritual Development and Transformation among College Students from Jesuit Higher Education Religions doi: 10.3390/rel11070333 Authors: Plante The college experience can be a critically important and enriching time for personal as well as academic growth and development. For many students, college is their first foray into a more independent world and lifestyle no longer under the careful, and sometimes critical, eyes of their parents, families,...
Religions, Vol. 11, Pages 331: Hoping against Hope: Dealing with Hopelessness in Ancient Times and Today † Religions doi: 10.3390/rel11070331 Authors: Joerg Rieger The hope of Abraham was “hope against hope,” the apostle Paul notes in a famous passage in his letter to the Romans 4:18. Such is the hope of the underdog, whose hope is not backed up by the powers that be, manifest by the prevalent empires of the day. Any discussion of hope in this context needs to deal...
Religions, Vol. 11, Pages 332: Media Representations of Religion, Spirituality and Non-Religion in Australia Religions doi: 10.3390/rel11070332 Authors: Enqi Weng Anna Halafoff Despite predictions of decline, religion has featured prominently in the public sphere and the media since the events of September 11, 2001. Previous research on media and religion in Australia post-September 11 has focused largely on its negative impacts, particularly on Muslim communities. This article, in...
Religions, Vol. 11, Pages 330: State Regulations and Divine Oppositions: An Ethnography of the Nine Emperor Gods Festival in Singapore Religions doi: 10.3390/rel11070330 Authors: Jie Lin Chia Studies of popular Chinese religions in Singapore have mostly focused on the relationship between Chinese religious practitioners and state regulations delimiting land for religious uses. Local scholars have also studied the state’s active construction of a domain within which local religions...
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Sci, Vol. 2, Pages 51: Process Controls of the Live Root Zone and Carbon Sequestration Capacity of the Sundarbans Mangrove Forest, Bangladesh Sci doi: 10.3390/sci2030051 Authors: Edwin J. Bomer Carol A. Wilson Tracy Elsey-Quirk The conservation of coastal wetland ecosystems, like mangrove forests and salt marshes, represents a critical strategy for mitigating atmospheric emissions and climate change in the 21st century. Yet the existence of these environments is threatened by human-induced...
Sci, Vol. 2, Pages 50: Automatic Detection of Dynamic and Static Activities of the Older Adults Using a Wearable Sensor and Support Vector Machines Sci doi: 10.3390/sci2030050 Authors: Jian Zhang Rahul Soangra Thurmon E. Lockhart Although Support Vector Machines (SVM) are widely used for classifying human motion patterns, their application in the automatic recognition of dynamic and static activities of daily life in the healthy older adults is limited. Using a body mounted wireless...
Sci, Vol. 2, Pages 49: Antimalarial Drugs in Ghana: A Case Study on Personal Preferences Sci doi: 10.3390/sci2030049 Authors: Prince Yeboah Arnold Donkor Forkuo Obed Kwabena Offe Amponsah Nana Ofori Adomako Ahmad Yaman Abdin Muhammad Jawad Nasim Pitsch Werner Anto Berko Panyin Eike Emrich Claus Jacob Malaria is a serious infection affecting millions of people in Africa. Our study investigated the personal preferences and applications of antimalarial medicines...
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Social Sciences, Vol. 9, Pages 114: COVID-19 Infects Real Estate Markets: Short and Mid-Run Effects on Housing Prices in Campania Region (Italy) Social Sciences doi: 10.3390/socsci9070114 Authors: Vincenzo Del Giudice Pierfrancesco De Paola Francesco Paolo Del Giudice The COVID-19 (also called “SARS‑CoV‑2”) pandemic is causing a dramatic reduction in consumption, with a further drop in prices and a decrease in workers’ per capita income. To this will...
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Toxins, Vol. 12, Pages 439: Immune Dysfunction in Uremia 2020 Toxins doi: 10.3390/toxins12070439 Authors: Cohen Cardiovascular disease and infections are major causes for the high incidence of morbidity and mortality of patients with chronic kidney disease. Both complications are directly or indirectly associated with disturbed functions or altered apoptotic rates of polymorphonuclear leukocytes, monocytes, lymphocytes, and dendritic cells. Normal responses of immune cells can be reduced,...
Toxins, Vol. 12, Pages 438: Structural and Functional Insights into the C-terminal Fragment of Insecticidal Vip3A Toxin of Bacillus thuringiensis Toxins doi: 10.3390/toxins12070438 Authors: Kun Jiang Yan Zhang Zhe Chen Dalei Wu Jun Cai Xiang Gao The vegetative insecticidal proteins (Vips) secreted by Bacillus thuringiensis are regarded as the new generation of insecticidal toxins because they have different insecticidal properties compared with commonly applied insecticidal...
Toxins, Vol. 12, Pages 437: Quantitative Measurement of Melittin in Asian Honeybee Venom Using a New Method Including UPLC-QqTOF-MS Toxins doi: 10.3390/toxins12070437 Authors: Sheng Huang Jianhua Wang Zeqin Guo Yan Wang Chundong Liu Asian honeybee venom is widely used in traditional oriental medicine. Melittin is the main component of Asian honeybee venom. In the present study, an ultra-performance liquid chromatography-quadrupole time-of-flight mass spectrometry (UPLC-QqTOF-MS)...
Toxins, Vol. 12, Pages 436: Co-Occurrence of Tetrodotoxin and Saxitoxins and Their Intra-Body Distribution in the Pufferfish Canthigaster valentini Toxins doi: 10.3390/toxins12070436 Authors: Hongchen Zhu Takayuki Sonoyama Misako Yamada Wei Gao Ryohei Tatsuno Tomohiro Takatani Osamu Arakawa Pufferfish of the family Tetraodontidae possess tetrodotoxin (TTX) and/or saxitoxins (STXs), but the toxin ratio differs, depending on the genus or species. In the present study,...
Toxins, Vol. 12, Pages 435: Shiga Toxin Selectively Upregulates Expression of Syndecan-4 and Adhesion Molecule ICAM-1 in Human Glomerular Microvascular Endothelium Toxins doi: 10.3390/toxins12070435 Authors: Elena B. Volokhina Wouter J. C. Feitz Lonneke M. Elders Thea J. A. M. van der Velden Nicole C. A. J. van de Kar Lambertus P. W. J. van den Heuvel Hemolytic uremic syndrome (HUS) is a severe renal disease that is often preceded by infection with Shiga toxin (Stx)-producing...
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TropicalMed, Vol. 5, Pages 112: Treatment of Severe COVID-19 with Tocilizumab Mitigates Cytokine Storm and Averts Mechanical Ventilation During Acute Respiratory Distress: A Case Report and Literature Review Tropical Medicine and Infectious Disease doi: 10.3390/tropicalmed5030112 Authors: Faryal Farooqi Naveen Dhawan Richard Morgan John Dinh Kester Nedd George Yatzkan COVID-19, caused by the novel severe acute respiratory coronavirus 2 (SARS-CoV-2), emerged in Wuhan, China,...
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Vaccines, Vol. 8, Pages 359: Porcine Parvovirus 7: Evolutionary Dynamics and Identification of Epitopes toward Vaccine Design Vaccines doi: 10.3390/vaccines8030359 Authors: Dongliang Wang Jinhui Mai Yi Yang Naidong Wang Porcine parvovirus 7 (PPV7) belonging to the genus Chapparvovirus in the family Parvoviridae, has been identified in the USA, Sweden, Poland, China, South Korea and Brazil. Our objective was to determine the phylogeny, estimate the time of origin and evolutionary...
Vaccines, Vol. 8, Pages 358: Strategies to Improve Vaccination among At-Risk Adults and the Elderly in Italy Vaccines doi: 10.3390/vaccines8030358 Authors: Giovanna Elisa Calabrò Alessia Tognetto Elettra Carini Silvia Mancinelli Laura Sarnari Vittoria Colamesta Walter Ricciardi Chiara de Waure The World Health Organization (WHO), the United States (US) Centers for Disease Control and Prevention (CDC), the European Center for Disease Control (ECDC), and the immunization...
Vaccines, Vol. 8, Pages 357: Characteristics of Adverse Events Following Immunization Reporting in Children: The Japanese Adverse Drug Event Report Database Vaccines doi: 10.3390/vaccines8030357 Authors: Aoi Noda Takamasa Sakai Masami Tsuchiya Gen Oyanagi Taku Obara Nariyasu Mano The present study aimed to describe the trends and characteristics of adverse events following immunization (AEFI) reporting for children in the Japanese Adverse Drug Event Report database (JADER)....
Vaccines, Vol. 8, Pages 355: Immunoinformatic Analysis of T- and B-Cell Epitopes for SARS-CoV-2 Vaccine Design Vaccines doi: 10.3390/vaccines8030355 Authors: Dongliang Wang Jinhui Mai Wenfeng Zhou Wanting Yu Yang Zhan Naidong Wang Neal D. Epstein Yi Yang Currently, there is limited knowledge about the immunological profiles of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). We used computer-based immunoinformatic analysis and the newly resolved 3-dimensional...
Vaccines, Vol. 8, Pages 356: Impact of Influenza Vaccination on Mortality in the Oldest Old: A Propensity Score-Matched Cohort Study Vaccines doi: 10.3390/vaccines8030356 Authors: Pauline Walzer Clémentine Estève Jeremy Barben Didier Menu Christine Cuenot Patrick Manckoundia Alain Putot Influenza remains a major cause of illness and death in geriatric populations. While the influenza vaccine has successfully reduced morbidity and mortality, its effectiveness is suspected...
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Viruses, Vol. 12, Pages 725: A Cut above the Rest: Characterization of the Assembly of a Large Viral Icosahedral Capsid Viruses doi: 10.3390/v12070725 Authors: Erin R. Reilly Milky K. Abajorga Cory Kiser Nurul Humaira Mohd Redzuan Zein Haidar Lily E. Adams Randy Diaz Juliana A. Pinzon André O. Hudson Lindsay W. Black Ru-Ching Hsia Susan T. Weintraub Julie A. Thomas The head of Salmonella virus SPN3US is composed of ~50 different proteins and is unusual...
Viruses, Vol. 12, Pages 724: STAT2 Limits Host Species Specificity of Human Metapneumovirus Viruses doi: 10.3390/v12070724 Authors: Meredith C. Rogers Margot Miranda-Katz Yu Zhang Tim D. Oury Melissa B. Uccellini Adolfo García-Sastre John V. Williams The host tropism of viral infection is determined by a variety of factors, from cell surface receptors to innate immune signaling. Many viruses encode proteins that interfere with host innate immune recognition in order...
Viruses, Vol. 12, Pages 723: Catching Common Cold Virus with a Net: Pyridostatin Forms Filaments in Tris Buffer That Trap Viruses—A Novel Antiviral Strategy? Viruses doi: 10.3390/v12070723 Authors: Antonio Real-Hohn Rong Zhu Haleh Ganjian Nahla Ibrahim Peter Hinterdorfer Heinrich Kowalski Dieter Blaas The neutrophil extracellular trap (ET) is a eukaryotic host defense machinery that operates by capturing and concentrating pathogens in a filamentous network manufactured...
Viruses, Vol. 12, Pages 721: Pseudomonas Phage PaBG—A Jumbo Member of an Old Parasite Family Viruses doi: 10.3390/v12070721 Authors: Peter Evseev Nina Sykilinda Anna Gorshkova Lidia Kurochkina Rustam Ziganshin Valentin Drucker Konstantin Miroshnikov Bacteriophage PaBG is a jumbo Myoviridae phage isolated from water of Lake Baikal. This phage has limited diffusion ability and thermal stability and infects a narrow range of Pseudomonas aeruginosa strains. Therefore, it...
Viruses, Vol. 12, Pages 720: West Nile Virus in Slovenia Viruses doi: 10.3390/v12070720 Authors: Nataša Knap Miša Korva Vladimir Ivović Katja Kalan Mateja Jelovšek Martin Sagadin Samo Zakotnik Katja Strašek Smrdel Jan Slunečko Tatjana Avšič-Županc West Nile virus (WNV) is a flavivirus transmitted by mosquitoes. Birds are the reservoir for the virus; humans, horses and other mammals are dead-end hosts. Infections caused by WNV in humans can vary from asymptomatic...
Viruses, Vol. 12, Pages 722: Cathepsin B Protease Facilitates Chikungunya Virus Envelope Protein-Mediated Infection via Endocytosis or Macropinocytosis Viruses doi: 10.3390/v12070722 Authors: Mai Izumida Hideki Hayashi Atsushi Tanaka Yoshinao Kubo Chikungunya virus (CHIKV) is an enveloped virus that enters host cells and transits within the endosomes before starting its replication cycle, the precise mechanism of which is yet to be elucidated. Endocytosis and endosome acidification...
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Water, Vol. 12, Pages 1919: Man-Induced Discrete Freshwater Discharge and Changes in Flow Structure and Bottom Turbulence in Altered Yeongsan Estuary, Korea Water doi: 10.3390/w12071919 Authors: KiRyong Kang Guan-hong Lee Flow measurements were performed in the altered Yeongsan estuary, Korea, in August 2011, to investigate changes in flow structure in the water column and turbulence characteristics very close to the bed. Comparison between the bottom turbulent kinetic energy (TKE)...
Water, Vol. 12, Pages 1918: Effect of Logarithmically Transformed IMERG Precipitation Observations in WRF 4D-Var Data Assimilation System Water doi: 10.3390/w12071918 Authors: Jiaying Zhang Liao-Fan Lin Rafael L. Bras Precipitation estimates from numerical weather prediction (NWP) models are uncertain. The uncertainties can be reduced by integrating precipitation observations into NWP models. This study assimilates Version 04 Integrated Multi-satellite Retrievals for the Global...
Water, Vol. 12, Pages 1917: Changes in Fungal Community Structure in Freshwater Canals across a Gradient of Urbanization Water doi: 10.3390/w12071917 Authors: Tianma Yuan Haihan Zhang Qiaoli Feng Xiangyu Wu Yixin Zhang Alan J. McCarthy Raju Sekar Fungi are an important, yet often, neglected component of the aquatic microflora, and is responsible for primary decomposition and further processing of organic matter. By comparison, the ecological roles of terrestrial fungi...
Water, Vol. 12, Pages 1916: Effects of Travel Speed and Collector on Evaluation of the Water Application Uniformity of a Center Pivot Irrigation System Water doi: 10.3390/w12071916 Authors: Yongchong Li Xin Hui Haijun Yan Diyi Chen Water application uniformity is an important performance parameter when designing and operating an irrigation system. Performance tests of a center pivot irrigation system equipped with fixed and rotated spray plate sprinklers (FSPS and RSPS, respectively)...
Water, Vol. 12, Pages 1915: Feedback Mechanism in Bifurcating River Systems: the Effect on Water-Level Sensitivity Water doi: 10.3390/w12071915 Authors: Matthijs R.A. Gensen Jord J. Warmink Fredrik Huthoff Suzanne J.M.H. Hulscher Accurate and reliable estimates of water levels are essential to assess flood risk in river systems. In current practice, uncertainties involved and the sensitivity of water levels to these uncertainties are studied in single-branch rivers, while many...
Water, Vol. 12, Pages 1911: Climate-Dependent Groundwater Discharge on Semi-Arid Inland Ephemeral Wetlands: Lessons from Holocene Sediments of Lagunas Reales in Central Spain Water doi: 10.3390/w12071911 Authors: Rosa Mediavilla Juan I. Santisteban Ignacio López-Cilla Luis Galán de Frutos África de la Hera-Portillo Wetlands are environments whose water balance is highly sensitive to climate change and human action. This sensitivity has allowed us to explore the relationships...
Water, Vol. 12, Pages 1913: Identifying Optimal Sites for a Rainwater-Harvesting Agricultural Scheme in Iran Using the Best-Worst Method and Fuzzy Logic in a GIS-Based Decision Support System Water doi: 10.3390/w12071913 Authors: Aghaloo Chiu Rainwater-harvesting (RWH) agriculture has been accepted as an effective approach to easing the overexploitation of groundwater and the associated socioeconomic impacts in arid and semiarid areas. However, the stability and reliability of the...
Water, Vol. 12, Pages 1914: Integrated Water Resources Management in Federations: The Examples of Brazil and Switzerland Water doi: 10.3390/w12071914 Authors: Miranda Reynard International water institutions worldwide consider integrated water resources management (IWRM) to be the most sustainable way to manage water. Governments have modified their legal and institutional framework in order to apply integrated water management tools in the river basin. Institutional challenges...
Water, Vol. 12, Pages 1912: Influence of Subsoiling on the Effective Precipitation of Farmland Based on a Distributed Hydrological Model Water doi: 10.3390/w12071912 Authors: Wang Wang Qin Lv Li Nie Liu He Effective precipitation plays an important role in crop growth, and subsoiling may have an impact on the effective precipitation of farmland. The question how subsoiling influences effective precipitations has prompted this research. The major objective...
Water, Vol. 12, Pages 1909: Monthly Precipitation Forecasts Using Wavelet Neural Networks Models in a Semiarid Environment Water doi: 10.3390/w12071909 Authors: Javier Estévez Juan Antonio Bellido-Jiménez Xiaodong Liu Amanda Penélope García-Marín Accurate forecast of hydrological data such as precipitation is critical in order to provide useful information for water resources management, playing a key role in different sectors. Traditional forecasting methods present many limitations...
Water, Vol. 12, Pages 1910: Experimental Assessment of the Flow Resistance of Coastal Wooden Fences Water doi: 10.3390/w12071910 Authors: Hoang Tung Dao Bas Hofland Marcel J. F. Stive Tri Mai Wooden fences are applied as a nature-based solution to support mangrove restoration along mangrove coasts in general and the Mekong Delta coast in particular. The simple structure uses vertical bamboo poles as a frame to store horizontal bamboo and tree branches (brushwood). Fence resistance...
Water, Vol. 12, Pages 1908: Key Determinants of Freshwater Gastropod Diversity and Distribution: The Implications for Conservation and Management Water doi: 10.3390/w12071908 Authors: Bae Park Freshwater organisms are facing threats from various natural and anthropogenic disturbances. Using data sampled on a nationwide scale from streams in South Korea, we identified the crucial environmental factors influencing the distribution and abundance of freshwater gastropods. We used nonmetric...
Water, Vol. 12, Pages 1907: Beyond Human Interventions on Complex Bays: Effects on Water and Wave Dynamics (Study Case Cádiz Bay, Spain) Water doi: 10.3390/w12071907 Authors: Carmen Zarzuelo Alejandro López-Ruiz Miguel Ortega-Sánchez Bays are coastal environments with significant socio-economic importance, which has led to the development of human interventions in their interior that can have an important impact on the water and wave dynamics, which in turn modify their morphodynamics...
Water, Vol. 12, Pages 1906: Identification of the Optimum Rain Gauge Network Density for Hydrological Modelling Based on Radar Rainfall Analysis Water doi: 10.3390/w12071906 Authors: Yeboah Gyasi-Agyei Rain gauges continue to be sources of rainfall data despite progress made in precipitation measurements using radar and satellite technology. There has been some work done on assessing the optimum rain gauge network density required for hydrological modelling, but without consensus. This...
Water, Vol. 12, Pages 1905: Ecological Environment Evaluation of Forest Ecosystem Nature Reserves Using an Unweighted Cloud Model Water doi: 10.3390/w12071905 Authors: Mengshi Xiang Xiaonan Lin Xiyan Yang Shanghong Zhang The ecological environment is the foundation of human survival and development, and forest ecosystem nature reserves play an important role in the protection of the ecological environment. The evaluation of forest ecosystem nature reserves facilitates the formulation...
Water, Vol. 12, Pages 1904: Phytoneuston and Chemical Composition of Surface Microlayer of Urban Water Bodies Water doi: 10.3390/w12071904 Authors: Józef Piotr Antonowicz Anna Kozak The concentration of chemical and biological parameters in the ecotone of the surface microlayer (SML) occurring between the hydrosphere and the atmosphere of urban water bodies was investigated. Parallel, sub-surface water (SUB) analyses were carried out to compare the SML properties with the water column....
Water, Vol. 12, Pages 1900: Macroinvertebrate Communities in a Lake of an Inter-Basin Water Transfer Project and Its Implications for Sustainable Management Water doi: 10.3390/w12071900 Authors: Wanxiang Jiang Baozhu Pan Jing Chen Xiaoming Jiang Henglun Shen Tianshun Zhu In the present study, we choose the Weishan Lake, one of important water transfer and storage lakes on the eastern route of the South-to-North Water Diversion Project (SNWD) in China, to clarify how the...
Water, Vol. 12, Pages 1902: Hydrologic Assessment of TRMM and GPM-Based Precipitation Products in Transboundary River Catchment (Chenab River, Pakistan) Water doi: 10.3390/w12071902 Authors: Ehtesham Ahmed Firas Al Janabi Jin Zhang Wenyu Yang Naeem Saddique Peter Krebs Water resources planning and management depend on the quality of climatic data, particularly rainfall data, for reliable hydrological modeling. This can be very problematic in transboundary rivers with limited...
Water, Vol. 12, Pages 1901: Flood Vulnerability Assessment for Prioritizing and Evaluating Rehabilitation of Ungauged Reservoirs Considering Climate Change Water doi: 10.3390/w12071901 Authors: Sang-Min Jun Moon-Seong Kang Soonho Hwang Jihoon Park Jung-Hun Song The objective of this research was to apply the flood vulnerability assessment to ungauged reservoirs for prioritizing and evaluating the reservoir rehabilitation according to climate change. The flood vulnerability...
Water, Vol. 12, Pages 1903: Rapid Sampling of Suspended and Floating Microplastics in Challenging Riverine and Coastal Water Environments in Japan Water doi: 10.3390/w12071903 Authors: Amila Abeynayaka Fujio Kojima Yoshikazu Miwa Nobuhiro Ito Yasuo Nihei Yu Fukunaga Yuga Yashima Norihiro Itsubo Environmental sampling plays an important role in quantitative and qualitative investigation of plastic pollution. Rivers are a major source, carrying plastic litter into...
Water, Vol. 12, Pages 1898: Multi-Objective Model Predictive Control for Real-Time Operation of a Multi-Reservoir System Water doi: 10.3390/w12071898 Authors: Nay Myo Lin Xin Tian Martine Rutten Edo Abraham José M. Maestre Nick van de Giesen This paper presents an extended Model Predictive Control scheme called Multi-objective Model Predictive Control (MOMPC) for real-time operation of a multi-reservoir system. The MOMPC approach incorporates the non-dominated sorting...
Water, Vol. 12, Pages 1899: Groundwater Parameter Inversion Using Topographic Constraints and a Zonal Adaptive Multiscale Procedure: A Case Study of an Alluvial Aquifer Water doi: 10.3390/w12071899 Authors: Dimitri Rambourg Philippe Ackerer Olivier Bildstein The identification of aquifer parameters (i.e., specific yield and hydraulic conductivity) and forcing terms (recharge) is crucial for the process of modeling groundwater flow and contamination. Inversion techniques allow the...
Water, Vol. 12, Pages 1896: Water–Energy–Food Nexus Framework for Promoting Regional Integration in Central Asia Water doi: 10.3390/w12071896 Authors: Olimjon Saidmamatov Inna Rudenko Stephan Pfister Jacek Koziel This paper focuses on regional integration through the lenses of the Water–Food–Energy (WEF) nexus, a concept putting strong emphasis on cross-sectoral and multi-level interactions as well as on resource interdependencies. There is an extensive amount...
Water, Vol. 12, Pages 1897: Antibiotic Resistance Genes Occurrence in Wastewaters from Selected Pharmaceutical Facilities in Nigeria Water doi: 10.3390/w12071897 Authors: Amarachukwu Obayiuwana Abasiofiok M. Ibekwe The proliferation of antibiotic-resistant bacteria (ARB) and the prevalence of antibiotic resistance genes (ARGs) in wastewaters are well-established factors that contribute to the reduced potency of antibiotics used in healthcare worldwide. The human health risk associated...
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