Harmandeep SinghIndian Journal of Nuclear Medicine 2020 35(3):194-196
Wed Jul 01, 2020 00:00
Piyush Chandra, Satish Nath, Deepti JainIndian Journal of Nuclear Medicine 2020 35(3):267-268 In the treatment of hepatocellular carcinoma, achieving complete pathological response (CPR) in explanted liver specimens following any locoregional treatments is associated with reduced recurrence rates and better posttransplant survival compared to the incomplete response. Here, we present the imaging findings of a patient who achieved CPR in the explanted liver following Y-90 SIR-Spheres® therapy.
Wed Jul 01, 2020 00:00
Ameya D PuranikIndian Journal of Nuclear Medicine 2020 35(3):197-199 There is a sudden upsurge in the literature over the last fortnight on strategies to be followed by imaging services during this SARS-CoV-2 global pandemic. This compilation of strategies, experiences, and precautions is intended to support nuclear medicine departments, as they make decisions regarding patient care. These guidelines are a good resource to tackle the current crisis, however, situations such as these may occur...
Wed Jul 01, 2020 00:00
Girish Kumar Parida, Adarsh Kumar, Sujata Mitra, Akchata Suman, Gopal Sonai MuthuIndian Journal of Nuclear Medicine 2020 35(3):258-259 Cutaneous squamous cell carcinoma (SCC) metastasizes most commonly to the regional lymph nodes and lungs. Metastasis to heart, although described in literature, is a very rare phenomenon. We present the 18F-fluorodeoxyglucose positron emission tomography–computed tomography findings in a 50-year-old woman who was a biopsy-proven case of SCC left foot, showing...
Wed Jul 01, 2020 00:00
Natesan RamamoorthyIndian Journal of Nuclear Medicine 2020 35(3):200-202 The growth of diagnostic nuclear medicine is substantially based on the development, availability, and regular clinical use of cyclotron-based positron emission tomography (PET) tracers. Apart from 18F (110 min) products, the radiometal 68Ga isotope (68 min) has found an increasingly wide clinical acceptance. There is hence much merit in identifying and fostering other radiometal positron emitters, of preferably longer half-life....
Wed Jul 01, 2020 00:00
Punit SharmaIndian Journal of Nuclear Medicine 2020 35(3):276-277
Wed Jul 01, 2020 00:00
Manish Ora, Aftab Hasan Nazar, Prasanta Kumar Pradhan, Prabhakar Mishra, Sukanta Barai, Amitabh Arya, Manish Dixit, Ashutosh Parashar, Sanjay GambhirIndian Journal of Nuclear Medicine 2020 35(3):203-209 Purpose of the Study: 18F-Fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) is used in the management of recurrent differentiated thyroid cancer (DTC) patients presented with rising thyroglobulin (Tg) or anti-Tg antibody (Atg) levels and negative whole-body I-131...
Wed Jul 01, 2020 00:00
SJ Seetharam, Vishnukumar Rajaraman, Nandini PanditIndian Journal of Nuclear Medicine 2020 35(3):253-254 Parathyroid hormone (PTH) is a key in maintaining calcium homeostasis. Decreased PTH will result in decreased bone remodeling and increased bone density. The major cause is iatrogenic injury to parathyroid gland. X-ray and dual-energy X-ray absorptiometry are used to identify the skeletal changes. Typical skeletal changes are metaphyseal sclerosis in long bones and sclerosis of vertebrae and...
Wed Jul 01, 2020 00:00
Hicham Asmi, Farida Bentayeb, Youssef Bouzekraoui, Faustino BonuttiIndian Journal of Nuclear Medicine 2020 35(3):210-215 Purpose: In single-photon emission computed tomography imaging, the presence of scatter degrades image quality. The goal of this study is to optimize the main- and sub-energy windows for triple-energy window (TEW) method using Monte Carlo SImulating Medical Imaging Nuclear Detectors (SIMIND) code for samarium-153 (Sm-153) imaging. Materials and Methods: The comparison is based...
Wed Jul 01, 2020 00:00
Suraj Kumar, Sarthak Tripathy, Sameer Rastogi, Avinash Upadhayay, Sneha Prakash, Shamim Ahmed ShamimIndian Journal of Nuclear Medicine 2020 35(3):262-263 Spontaneous cavitation in primary lung malignancies although common, but is rare in secondary metastatic lung tumors. We present a case of 20-year-old male who presented with cavitary left lung lesion 1-year postexcision of the left tibia osteosarcoma on 18F-fluorodeoxyglucose positron emission tomography-computed tomography which on histopathology...
Wed Jul 01, 2020 00:00
Seyedshahab Banihashem, Mehdi Arabzadeh, Reyhaneh Sadat Jafarian Bahri, Mohsen QutbiIndian Journal of Nuclear Medicine 2020 35(3):216-221 Purpose: The objective is to investigate psychological status and quality of life (QoL) using Hospital Anxiety and Depression Scale (HADS) and Short-Form (36) Health Survey (SF-36) questionnaires in patients with proven differentiated thyroid cancer (DTC) who are referred for radioactive iodine (RAI) ablation before, during, and after treatment. Methods: Of...
Wed Jul 01, 2020 00:00
Nitin Gupta, Ram Kumar Elumalai, Ritu Verma, Ethel Shangne Belho, Shashi DhawanIndian Journal of Nuclear Medicine 2020 35(3):271-273 Prostate-specific membrane antigen (PSMA) is a type II transmembrane glycoprotein which is overexpressed in prostate cancer. However, the widespread use of PSMA positron-emission tomography (PET) scan revealed various nonprostatic PSMA-avid diseases. Here we present a report of a known case of carcinoma prostate, post orchidectomy, radiotherapy, on hormonal therapy...
Wed Jul 01, 2020 00:00
Pramukh Kulkarni, Simon Shelley, Indirani M Elangoven, A Jaykanth, Asra Patel Ejaz, Nikita Sampathi RaoIndian Journal of Nuclear Medicine 2020 35(3):222-225 Melioidosis is an emerging infectious disease in India. The disease has a crippling effect on the patient owing to its widespread dissemination and complications post bacteremia. The role of 18-fluorine-fluorodeoxyglucose (FDG) positron emission tomography–computed tomography (PET-CT) is becoming increasingly important in terms of documenting...
Wed Jul 01, 2020 00:00
V RangarajanIndian Journal of Nuclear Medicine 2020 35(3):191-193
Wed Jul 01, 2020 00:00
Koramadai Karuppusamy Kamaleshwaran, Malipedda Suneelkumar, Raghunathan Madhusairam, Edathuruthy Kalarikal Radhakrishnan, Soundararajan Arunpandiyan, Vasumathi Jayaraj ArnoldIndian Journal of Nuclear Medicine 2020 35(3):226-228 Somatostatin receptor-targeted alpha radionuclide therapies have been introduced including actinium-225 labeled tetraazacyclododecanetetraacetic acid–octreotide (Ac-225 DOTATATE) for advanced metastatic neuroendocrine tumors (NET). Very limited data are available on the...
Wed Jul 01, 2020 00:00
Ram Kumar Elumalai, Nitin Gupta, Ritu Verma, Ethel Shangne BelhoIndian Journal of Nuclear Medicine 2020 35(3):251-252 Bladder cancer is one of the most common malignancies of the urinary tract. Cutaneous metastasis of bladder carcinoma is extremely rare with a limited number of cases, resulting mainly from iatrogenic seeding. Here, we present scan findings of cutaneous metastasis in a known case of carcinoma urinary bladder. The 18F FDG PET/CT scan revealed FDG avid nodular thickening of the...
Wed Jul 01, 2020 00:00
Ankur Pruthi, Harvinder Singh, Yogender Rawath, Navjot KaurIndian Journal of Nuclear Medicine 2020 35(3):229-231 Hepatic veins and inferior vena cava are opacified during the delayed venous phase on triphasic contrast-enhanced computed tomography (CECT) abdomen scan. However, their early opacification/visualization in the arterial phase is usually due to retrograde flow of intravenous contrast from the right atrium in patients with right-sided heart failure or right ventricular dysfunction. Awareness...
Wed Jul 01, 2020 00:00
Sharjeel Usmani, Samreen Muzaffar, Uzma Rahman, Fareeda Al Kandari, Najeeb AhmedIndian Journal of Nuclear Medicine 2020 35(3):255-257 The dissemination and autotransplantation of viable splenic tissue in different anatomic compartments of the body can present a diagnostic dilemma, especially when metastatic disease is suspected. We report a case of a 30-year-old male with well-differentiated gastric neuroendocrine tumor (Grade II) treated with surgery. Follow-up 68Ga-DOTA-NOC demonstrated a suspicious...
Wed Jul 01, 2020 00:00
Ankur Pruthi, Pawan Kirtani, Parmeshwar Joshi, Navjot KaurIndian Journal of Nuclear Medicine 2020 35(3):232-234 Sarcoidosis is a chronic granulomatous disorder of unknown etiology which primarily affects the respiratory system. However, 0.5%–2.5% of patients with sarcoidosis show muscle involvement, namely sarcoid myopathy. F-18 Fluorodeoxyglucose positron-emission tomography (F-18 FDG PET) has become an important component of the diagnostic algorithm of these patients, owing to its ability to...
Wed Jul 01, 2020 00:00
Piyush Chandra, Satish Nath, Chitrambalam Shanmuga SundaramIndian Journal of Nuclear Medicine 2020 35(3):260-261 Leucine-rich glioma-inactivated 1 (LGI1) antibody encephalitis is an emerging autoimmune disorder with antibodies to the voltage-gated potassium channel complex. Here, we report clinico-imaging findings of a 77-year-old female presenting with acute-onset seizures, normal magnetic resonance imaging and with abnormal fluordeoxygluose positron-emission tomography-computed tomography and...
Wed Jul 01, 2020 00:00
Nivedita Rana, Harmandeep Singh, Rakhee Vatsa, Ankit Watts, Bhagwant Rai MittalIndian Journal of Nuclear Medicine 2020 35(3):235-237 Artifacts in positron emission tomography (PET)/computed tomography imaging can result from a number of factors. Presence of imaging artifacts affects interpretation and can sometimes render the image uninterpretable. Correction of artifacts can be attempted by reprocessing of data. In the present study, one PET maximum intensity projection image artifact was corrected...
Wed Jul 01, 2020 00:00
Nitin Gupta, Abhishek KhareIndian Journal of Nuclear Medicine 2020 35(3):264-266 Meningiomas arise from meningothelial cells of the arachnoid membranes. They are classified into three grades according to the WHO criteria, Grade I (Benign), Grade II (atypical), and Grade III (anaplastic). Radiological and structural imaging computed tomography (CT) and magnetic resonance imaging are done routinely for defining the location, extent, and follow-up. However, these imaging techniques have their limitations....
Wed Jul 01, 2020 00:00
Lokeshwaran Madurai Kalimuthu, Aftab Hasan Nazar, Prasanta Kumar PradhanIndian Journal of Nuclear Medicine 2020 35(3):238-240 Tc-99m-methylene diphosphonate (MDP) bone scintigraphy is mainly directed toward identifying sites of altered skeletal metabolism and abnormal foci of calcium phosphate deposition due to various etiologies. One of the requirements of an ideal bone scintigraphy is little or no extraosseous uptake. Nonosseous uptake of MDP in the bone scintigraphy is an unusual finding....
Wed Jul 01, 2020 00:00
Ali Sellem, Yazid Mahjoub, Wassim Elajmi, Hatem HammamiIndian Journal of Nuclear Medicine 2020 35(3):269-270 A 65-year-old woman presented with a neuroendocrine pancreatic head tumor and known liver and bone metastasis. We performed Tc-99m-tektrotyd scintigraphy on this patient, which showed more developed diffuse bone metastases, in addition to the known lesions.
Wed Jul 01, 2020 00:00
Saurabh Arora, Sameer Rastogi, Shamim Ahmed Shamim, Adarsh Wamanrao Barward, Benjamin Leroy PassahIndian Journal of Nuclear Medicine 2020 35(3):241-243 Gastric neuroendocrine tumors (G-NETs) express somatostatin receptors (SSTR), which can be imaged using radiolabeled somatostatin analogs, including 68Ga-DOTA octreotide analogs. SSTR expression is also seen in activated lymphocytes and macrophages, which might result in false-positive results on SSTR imaging, in patients with coexistent granulomatous...
Wed Jul 01, 2020 00:00
Maria Mathew DSouza, Rajnish Sharma, Abhinav JaiminiIndian Journal of Nuclear Medicine 2020 35(3):274-275
Wed Jul 01, 2020 00:00
Nikhil Seniaray, Ritu Verma, Rajeev Ranjan, Ethel Belho, Harsh MahajanIndian Journal of Nuclear Medicine 2020 35(3):244-247 New onset refractory status epilepticus (NORSE), is a rare, neurological condition characterised by prolonged periods of refractory epileptic seizure with no readily identifiable cause in otherwise healthy individuals. Anatomical imaging like MRI and serology is usually unremarkable. In patients who have underlying etiology as auto-immune encephalitis without any evidence...
Wed Jul 01, 2020 00:00
Rashid Rasheed, Syed Ali Raza Naqi, Nidda Saeed, Shahid RasheedIndian Journal of Nuclear Medicine 2020 35(3):278-280
Wed Jul 01, 2020 00:00
Cystic echinococcosis (CE), caused by the cestode Echinococcus granulosus, is a worldwide chronic zoonosis. Albendazole (ABZ) and mebendazole are effective against CE, but a high dosage in a long-term period is usually required. In this study, we evaluate the effects of DNA damage repair inhibitor (i.e., Veliparib) in combination with artesunate (AS) on hydatid cysts. For the in vitro assay, protoscoleces of E. granulosus (E.g PSCs) were incubated with low AS (AS-L, 65 μM), moderate AS (AS-M, 130 μM),...
Sat Jul 04, 2020 21:35
Since December 2019, the pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes coronavirus disease 2019 (Covid-19), has resulted in high morbidity and mortality worldwide. New York State emerged as an epicenter of the outbreak in the United States,…
Mon Jun 29, 2020 03:00
Abstract Rationale Anabolic androgenic steroids are used to improve physical performance or increase lean muscle mass. About one-third of users develop a dependency syndrome, which is characterized by elevated rates of psychopathology, cognitive impairments, and aggressive and antisocial behaviors. The mechanisms behind these intra- and interpersonal problems are not known. Objective...
Sun Jul 05, 2020 03:00
In recent years, immune checkpoint inhibitors have been widely used as a crucial therapy in malignant tumors. Immune checkpoint inhibitors can cause various autoimmune side effects called immune-related advers...
Sat Jul 04, 2020 03:00
Elbow flexion reconstruction after arm-sparing excision for high-grade triton sarcoma: a case report
Soft tissue sarcomas affecting the root of an upper extremity raise the question of limb amputation depending on their location, size, and malignancy. Malignant triton tumors are a rare subtype of neurofibrosa...
Sat Jul 04, 2020 03:00
Nutcracker syndrome is a rare disorder caused by compression of the left renal vein, usually between the aorta and the superior mesenteric artery. It typically presents with left-sided abdominal pain and hemat...
Fri Jul 03, 2020 03:00
Teriparatide is a homolog of human parathyroid hormone (1–34), which is approved for the treatment of postmenopausal and glucocorticoid-induced osteoporosis. Several minor and transient side effects have been ...
Fri Jul 03, 2020 03:00
Abstract Purpose Cripto-1 also known as teratoma-derived growth factor 1 (TDGF-1) belongs to the EGF-CFC family of growth factor-like molecules. Cripto-1 is involved with embryonic development and not expressed in adult tissue, but some tumours are accompanied by reactivation. Methods The aim of this study was to evaluate the immunohistochemical expression...
Sun Jul 05, 2020 02:12
Abstract Introduction Cheilitis granulomatosa is an idiopathic granulomatous disorder which is rare and cosmetically disturbing. It presents with a persistent painless labial swelling which obscure etiology. Diagnosis is mainly based on the histopathological features following biopsy. There is no definitive treatment of this disease, reason being its lack of well-defined etiology. It has been proven largely resistant to most of the...
Sat Jul 04, 2020 03:00
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