Nature Communications, Published online: 03 July 2020; doi:10.1038/s41467-020-17151-2Cellular nonsense-mediated mRNA decay (NMD) has been shown to play a role in defense against RNA viruses. Here, Zhao et al. show that NMD restricts the DNA virus Kaposi sarcoma-associated herpesvirus (KSHV) via targeting both cellular and viral transcripts leading to inhibition of KSHV lytic reactivation.
Fri Jul 03, 2020 03:00
Nature Communications, Published online: 03 July 2020; doi:10.1038/s41467-020-17097-5CD4+ T helper cells producing IL-17A (TH17 cells) can take on pathogenic or anti-inflammatory functions in context-specific manners. Here the authors show that the anti-inflammatory fate of TH17 cells contributes, via TGF-β signaling and induction of IL-10, to host immune tolerance, but also simultaneously dampens protective immunity against S. aureus.
Fri Jul 03, 2020 03:00
Nature Communications, Published online: 03 July 2020; doi:10.1038/s41467-020-17196-3During development, oriented cell division is important to proper body axis extension. Here, the authors show that sphingolipids are required to direct spindle rotation and oriented mitosis via Anthrax receptor palmitoylation in zebrafish gastrulation.
Fri Jul 03, 2020 03:00
Nature Communications, Published online: 03 July 2020; doi:10.1038/s41467-020-17149-wThree-colour FRET is a powerful tool to study macromolecular conformational dynamics, but is temporally limited due to the experimental complexity. Here the authors develop experimental and analytical methods for probing submillisecond-time scale dynamics using single continuous-wave excitation.
Fri Jul 03, 2020 03:00
Nature Communications, Published online: 03 July 2020; doi:10.1038/s41467-020-17109-4In mammals, DNA methylation patterns are established by two de novo DNA methyltransferases, DNMT3A and DNMT3B. Here the authors report the crystal structures of DNMT3B in complex with both CpG and CpA DNA, providing insight into the substrate-recognition mechanism underpinning the divergent genomic methylation activities of DNMT3A and DNMT3B.
Fri Jul 03, 2020 03:00
Nature Communications, Published online: 03 July 2020; doi:10.1038/s41467-020-17132-5The discovery of atomically precise metal nanoclusters is generally unpredictable, and there are few examples of their rational synthesis. Here, the authors report the de novo design of Au36(SR)24 nanoclusters, from theoretical prediction to experimental synthesis and characterization of physicochemical properties.
Fri Jul 03, 2020 03:00
Nature Communications, Published online: 03 July 2020; doi:10.1038/s41467-020-17191-8Available genomics studies have mostly focused on planktonic centric diatom. Here, the authors report the genome assembly of the marine biofilm-forming diatom Seminavis robusta and the resequencing data of a panel of accessions to reveal their evolutionary adaptations.
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Related Articles LMA® Protector™ versus traditional LMA to perform endobronchial ultrasound-guided transbronchial needle aspiration: a retrospective analysis. Minerva Anestesiol. 2019 Jul;85(7):756-762 Authors: Zamparelli E, Fiorelli A, La Cerra G, Guarino C, Santoriello E, Buono S, Corcione A, Rispoli M Abstract BACKGROUND: The aim of this study was to evaluate the use of laryngeal mask airway (LMA)® Protector™ by comparison with traditional...
Fri Jul 03, 2020 13:41
Related Articles Improved Visualization of Focal Cortical Dysplasia With Surface-Based Multiparametric Quantitative MRI. Front Neurosci. 2020;14:622 Authors: Maiworm M, Nöth U, Hattingen E, Steinmetz H, Knake S, Rosenow F, Deichmann R, Wagner M, Gracien RM Abstract Purpose: In the clinical routine, detection of focal cortical dysplasia (FCD) by visual inspection is challenging. Still, information about the presence and location of FCD is highly...
Fri Jul 03, 2020 13:34
Related Articles Secretion and Function of Pituitary Prolactin in Evolutionary Perspective. Front Neurosci. 2020;14:621 Authors: Dobolyi A, Oláh S, Keller D, Kumari R, Fazekas EA, Csikós V, Renner É, Cservenák M Abstract The hypothalamo-pituitary system developed in early vertebrates. Prolactin is an ancient vertebrate hormone released from the pituitary that exerts particularly diverse functions. The purpose of the review is to take a comparative...
Fri Jul 03, 2020 13:34
Related Articles The Cardiorespiratory Network in Healthy First-Degree Relatives of Schizophrenic Patients. Front Neurosci. 2020;14:617 Authors: Schulz S, Haueisen J, Bär KJ, Voss A Abstract Impaired heart rate- and respiratory regulatory processes as a sign of an autonomic dysfunction seems to be obviously present in patients suffering from schizophrenia. Since the linear and non-linear couplings within the cardiorespiratory system with respiration...
Fri Jul 03, 2020 13:34
Related Articles Increased Plasma Level of Longevity Protein Klotho as a Potential Indicator of Cognitive Function Preservation in Patients With Schizophrenia. Front Neurosci. 2020;14:610 Authors: Xiong JW, Zhan JQ, Luo T, Chen HB, Wan QG, Wang Y, Wei B, Yang YJ Abstract Cognitive impairments are a core feature of schizophrenia. Klotho is an anti-aging protein with demonstrated cognitive-enhancing effects on the brain. The purpose of this study...
Fri Jul 03, 2020 13:34
Related Articles Decoding the Attended Speaker From EEG Using Adaptive Evaluation Intervals Captures Fluctuations in Attentional Listening. Front Neurosci. 2020;14:603 Authors: Jaeger M, Mirkovic B, Bleichner MG, Debener S Abstract Listeners differ in their ability to attend to a speech stream in the presence of a competing sound. Differences in speech intelligibility in noise cannot be fully explained by the hearing ability which suggests the...
Fri Jul 03, 2020 13:34
Related Articles Behavioral Phenotype in the TgF344-AD Rat Model of Alzheimer's Disease. Front Neurosci. 2020;14:601 Authors: Saré RM, Cooke SK, Krych L, Zerfas PM, Cohen RM, Smith CB Abstract Alzheimer's disease (AD) is a progressive neurodegenerative disease resulting in cognitive decline. A unique rat model, TgF344-AD, recapitulates pathological hallmarks of AD. We used a longitudinal design to address the timing of expression of behavioral...
Fri Jul 03, 2020 13:34
Related Articles Commentary: Alpha Synchrony and the Neurofeedback Control of Spatial Attention. Front Neurosci. 2020;14:597 Authors: Gundlach C, Forschack N PMID: 32612505 [PubMed]
Fri Jul 03, 2020 13:34
Related Articles Reorganization of Brain White Matter in Persistent Idiopathic Tinnitus Patients Without Hearing Loss: Evidence From Baseline Data. Front Neurosci. 2020;14:591 Authors: Chen Q, Wang Z, Lv H, Zhao P, Yang Z, Gong S, Wang Z Abstract It remains unknown whether tinnitus or tinnitus-related hearing loss (HL) could indirectly impair or reshape the white matter (WM) of the human brain. We aim to explore the possible brain WM change...
Fri Jul 03, 2020 13:34
Related Articles Peripheral and Central Nervous System Immune Response Crosstalk in Amyotrophic Lateral Sclerosis. Front Neurosci. 2020;14:575 Authors: Liu Z, Cheng X, Zhong S, Zhang X, Liu C, Liu F, Zhao C Abstract Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by muscle weakness due to the degeneration of the upper and lower motor neurons. Neuroinflammation is known as a prominent pathological feature...
Fri Jul 03, 2020 13:34
Related Articles One Is Not Enough: Understanding and Modeling Polysubstance Use. Front Neurosci. 2020;14:569 Authors: Crummy EA, O'Neal TJ, Baskin BM, Ferguson SM Abstract Substance use disorder (SUD) is a chronic, relapsing disease with a highly multifaceted pathology that includes (but is not limited to) sensitivity to drug-associated cues, negative affect, and motivation to maintain drug consumption. SUDs are highly prevalent, with 35 million...
Fri Jul 03, 2020 13:34
Related Articles Formal String Instrument Training in a Class Setting Enhances Cognitive and Sensorimotor Development of Primary School Children. Front Neurosci. 2020;14:567 Authors: James CE, Zuber S, Dupuis-Lozeron E, Abdili L, Gervaise D, Kliegel M Abstract This cluster randomized controlled trial provides evidence that focused musical instrumental practice, in comparison to traditional sensitization to music, provokes multiple transfer effects...
Fri Jul 03, 2020 13:34
Related Articles The Impact of Vision Loss on Allocentric Spatial Coding. Front Neurosci. 2020;14:565 Authors: Martolini C, Cappagli G, Luparia A, Signorini S, Gori M Abstract Several works have demonstrated that visual experience plays a critical role in the development of allocentric spatial coding. Indeed, while children with a typical development start to code space by relying on allocentric landmarks from the first year of life, blind children...
Fri Jul 03, 2020 13:34
Related Articles Efficacy of THN201, a Combination of Donepezil and Mefloquine, to Reverse Neurocognitive Deficits in Alzheimer's Disease. Front Neurosci. 2020;14:563 Authors: Droguerre M, Duchêne A, Picoli C, Portal B, Lejards C, Guiard BP, Meunier J, Villard V, Déglon N, Hamon M, Mouthon F, Charvériat M Abstract Donepezil (DPZ) is an acetylcholinesterase inhibitor used in Alzheimer's disease to restore cognitive functions but is endowed with...
Fri Jul 03, 2020 13:34
Related Articles Odor Modulates Hand Movements in a Reach-to-Grasp Task. Front Neurosci. 2020;14:560 Authors: Yang Y, Wang X Abstract Recent evidence suggests that target-relevant sensory stimuli (i.e., visual, auditory, and olfactory) can play important roles in the motor system. However, little is known about the effects of olfactory information on reaching and grasping movements. To determine whether odor stimuli affect hand movements, the...
Fri Jul 03, 2020 13:34
Related Articles Non-invasive High Frequency Repetitive Transcranial Magnetic Stimulation (hfrTMS) Robustly Activates Molecular Pathways Implicated in Neuronal Growth and Synaptic Plasticity in Select Populations of Neurons. Front Neurosci. 2020;14:558 Authors: Fujiki M, Yee KM, Steward O Abstract Patterns of neuronal activity that induce synaptic plasticity and memory storage activate kinase cascades in neurons that are thought to be part of...
Fri Jul 03, 2020 13:34
Related Articles A Fully Automated Method for Segmenting Arteries and Quantifying Vessel Radii on Magnetic Resonance Angiography Images of Varying Projection Thickness. Front Neurosci. 2020;14:537 Authors: Avadiappan S, Payabvash S, Morrison MA, Jakary A, Hess CP, Lupo JM Abstract Purpose: Precise quantification of cerebral arteries can help with differentiation and prognostication of cerebrovascular disease. Existing image processing and segmentation...
Fri Jul 03, 2020 13:34
Related Articles LRRK2 Phosphorylation, More Than an Epiphenomenon. Front Neurosci. 2020;14:527 Authors: Marchand A, Drouyer M, Sarchione A, Chartier-Harlin MC, Taymans JM Abstract Mutations in the Leucine Rich Repeat Kinase 2 (LRRK2) gene are linked to autosomal dominant Parkinson's disease (PD), and genetic variations at the LRRK2 locus are associated with an increased risk for sporadic PD. This gene encodes a kinase that is physiologically...
Fri Jul 03, 2020 13:34
Related Articles Mfsd2a Reverses Spatial Learning and Memory Impairment Caused by Chronic Cerebral Hypoperfusion via Protection of the Blood-Brain Barrier. Front Neurosci. 2020;14:461 Authors: Qu C, Song H, Shen J, Xu L, Li Y, Qu C, Li T, Zhang J Abstract Disruption of the blood-brain barrier (BBB) can lead to cognitive impairment. Major facilitator superfamily domain-containing protein 2a (Mfsd2a) is a newly discovered protein that is essential...
Fri Jul 03, 2020 13:34
Related Articles Bridging the Gap Between Vessels and Nerves in Fabry Disease. Front Neurosci. 2020;14:448 Authors: Forstenpointner J, Sendel M, Moeller P, Reimer M, Canaan-Kühl S, Gaedeke J, Rehm S, Hüllemann P, Gierthmühlen J, Baron R Abstract Purpose: Fabry disease frequently includes pain as an early disease feature, which was characterized as a dysfunctional processing of somatosensory information in various studies. The pathomechanism...
Fri Jul 03, 2020 13:34
Related Articles Bibliometric Analysis of Exercise and Neuropathic Pain Research. J Pain Res. 2020;13:1533-1545 Authors: Chen YM, Wang XQ Abstract Background: Neuropathic pain, a type of chronic pain, is difficult to treat clinically. Mounting evidence suggests that exercise can effectively ease neuropathic pain, and the number of publications related to exercise and neuropathic pain has increased over time. However, bibliometrics is rarely...
Fri Jul 03, 2020 13:22
Related Articles Basics and Frontiers on Pancreatic Cancer for Radiation Oncology: Target Delineation, SBRT, SIB technique, MRgRT, Particle Therapy, Immunotherapy and Clinical Guidelines. Cancers (Basel). 2020 Jun 29;12(7): Authors: Cellini F, Arcelli A, Simoni N, Caravatta L, Buwenge M, Calabrese A, Brunetti O, Genovesi D, Mazzarotto R, Deodato F, Mattiucci GC, Silvestris N, Valentini V, Morganti AG Abstract Pancreatic cancer represents a modern...
Fri Jul 03, 2020 13:22
New England Journal of Medicine, Ahead of Print.
Thu Jul 02, 2020 07:00
Related Articles The comparison of Real-time-PCR-HRM and Microscopy Methods for Detection of Mixed Plasmodium spp. Infections in Laghman Province, Afghanistan. Infect Disord Drug Targets. 2020 Jul 02;: Authors: Dalimi A, Mosawi SH Abstract BACKGROUND: Laghman province, in the east of the Afghanistan, is one of the most malaria endemic regions with an eminence of Plasmodium vivax and Plasmodium falciparum. So far, no study has been conducted...
Fri Jul 03, 2020 17:12
Related Articles Mechanistic insights into the anticandidal action of Vanillin reveal disruption of cell surface integrity and mitochondrial functioning. Infect Disord Drug Targets. 2020 Jul 02;: Authors: Saibabu V, Fatima Z, Khan LA, Hameed S Abstract BACKGROUND: Considering the emergence of multidrug resistance (MDR) in prevalent human fungal pathogen, Candida albicans, there is parallel spurt in development of novel strategies aimed to disrupt...
Fri Jul 03, 2020 17:12
Purpose One of the main pathophysiological mechanisms of chronic obstructive pulmonary disease is inflammation, which has been associated with lymphadenopathy. Intrapulmonary lymph nodes can be identified on CT as perifissural nodules (PFN). We investigated the association between the number and size of PFNs and measures of COPD severity. Materials and Methods CT images were obtained from COPDGene. 50 subjects were randomly...
Fri Jul 03, 2020 03:00
The basic helix-loop-helix (bHLH) transcription factors (TFs) have been identified and functionally characterized in many plants. However, no comprehensive analysis of the bHLH family in papaya (Carica papaya L.) has been reported previously. Here, a total of 73 CpbHLHs were identified in papaya, and these genes were classified into 18 subfamilies based on phylogenetic analysis. Almost all of the CpbHLHs in the same subfamily shared similar gene structures and protein motifs according to analysis...
Fri Jul 03, 2020 03:00
Recent and continued progress in the scale and sophistication of phylogenetic research has yielded substantial advances in knowledge of the tree of life; however, segments of that tree remain unresolved and continue to produce contradicting or unstable results. These poorly resolved relationships may be the product of methodological shortcomings or of an evolutionary history that did not generate the signal traits needed for its eventual reconstruction. Relationships within the euteleost fish family...
Fri Jul 03, 2020 03:00
The rapid development of the SARS-CoV-2 mediated COVID-19 pandemic has been the cause of significant health concern, highlighting the immediate need for effective antivirals. SARS-CoV-2 is an RNA virus that has an inherently high mutation rate. These mutations drive viral evolution and genome variability, thereby facilitating viruses to have rapid antigenic shifting to evade host immunity and to develop drug resistance. Viral RNA-dependent RNA polymerases (RdRp) perform viral genome duplication and...
Fri Jul 03, 2020 03:00
Successful reproduction and survival are crucial to the continuation and resilience of corals globally. As reef waters warm due to climate change, episodic largescale tropical storms are becoming more frequent, drastically altering the near shore water quality for short periods of time. Therefore, it is critical that we understand the effects warming waters, fresh water input, and run-off have on sexual reproduction of coral. To better understand the effects of these near shore stressors on Hawaiian...
Fri Jul 03, 2020 03:00
Background Xyleborus affinis Eichhoff (Coleoptera: Curculionidae) is an ambrosia beetle reported to affect avocado trees (Persea americana Mill.). The use of the entomopathogenic fungus (EPF) Beauveria bassiana (Bals.-Criv.) Vuill. for ambrosia beetle control represents an alternative to insecticides. Methods This study was designed in two stages to select B. bassiana strains with potential to control X. affinis females. In the first stage, 19 B. bassiana Mexican strains from EPF collection,...
Fri Jul 03, 2020 03:00
Background Chrysanthemum boreale Makino (Anthemideae, Asteraceae) is a plant of economic, ornamental and medicinal importance. We characterized and compared the chloroplast genomes of three C. boreale strains. These were collected from different geographic regions of Korea and varied in floral morphology. Methods The chloroplast genomes were obtained by next-generation sequencing techniques, assembled de novo, annotated, and compared with one another. Phylogenetic analysis placed them...
Fri Jul 03, 2020 03:00
Frogs of the genus Microhyla include some of the world’s smallest amphibians and represent the largest radiation of Asian microhylids, currently encompassing 50 species, distributed across the Oriental biogeographic region. The genus Microhyla remains one of the taxonomically most challenging groups of Asian frogs and was found to be paraphyletic with respect to large-sized fossorial Glyphoglossus. In this study we present a time-calibrated phylogeny for frogs in the genus Microhyla, and discuss...
Fri Jul 03, 2020 03:00
Few coral reefs remain unscathed by mass bleaching over the past several decades, and much of the coral reef science conducted today relates in some way to the causes, consequences, or recovery pathways of bleaching events. Most studies portray a simple cause and effect relationship between anomalously high summer temperatures and bleaching, which is understandable given that bleaching rarely occurs outside these unusually warm times. However, the statistical skill with which temperature captures...
Fri Jul 03, 2020 03:00
According to Spearman’s law of diminishing returns (SLODR), IQ test scores are more g saturated among those with low, compared to those with high, ability. The present simulation shows that such difference in saturation can be observed if test scores are affected by a disturbing factor, for example, low motivation, illness, or linguistic confusion, that varies in magnitude between individuals. More contemporary criteria of SLODR can also be satisfied if test scores are affected by disturbance, especially...
Fri Jul 03, 2020 03:00
Here we report on exceptional preservation of remains of the frog Eorubeta nevadensis in deposits of the Sheep Pass Formation, ranging from Late Cretaceous to Eocene, in the south Egan Range, Nevada. This formation represents a lacustrine basin within the Sevier retroarc hinterland. The formation is subdivided into six members (A–F); of interest here are members B and C. The base of member B is ?uppermost Cretaceous-Paleocene, while member C is Paleocene. Member B frogs are preserved in three taphonomic...
Fri Jul 03, 2020 03:00
Objective: Affective symptoms are common in patients with head-and-neck cancer. This study determined the association between the presence of aspiration and symptoms of anxiety and depression, as well as patient characteristics in patients with head-and-neck cancer and dysphagia. Methods: Eighty-four patients with head-and-neck cancer and dysphagia completed the Hospital Anxiety and Depression Scale and underwent a standardized fiberoptic endoscopic evaluation of swallowing. Linear regression analysis...
Fri Jul 03, 2020 12:19
Abstract Purpose of Review To report the association between desquamative inflammatory vaginitis and Crohn’s disease in 4 women. Recent Findings Extraintestinal manifestations of inflammatory bowel disease (IBD) are a result of a complex interplay of multiple factors and these may or may not follow an independent course. Vulvar sequelae...
Fri Jul 03, 2020 03:00
Abstract We describe traditional antimicrobial stewardship program (ASP) activities with a discussion of how these activities can be refocused in the setting of the COVID-19 pandemic. Additionally, we discuss possible adverse consequences of ASP attention diversion on COVID-19 response efforts and overall implications for future pandemic planning. We also discuss ASP in collaboration with other groups within health systems and how COVID-19 may affect these relationships long...
Fri Jul 03, 2020 03:00
Oral health problems are common among pregnant women. The objective of this study was to examine the effectiveness of motivational interviewing (MI) as a behavior‐change technique to enhance self‐efficacy and oral health among pregnant women. A randomized controlled trial was conducted with 112 pregnant Iranian women. Women in the intervention group received an education program on oral health using MI during two face‐to‐face sessions, along with routine health education (two 1‐h lectures on oral...
Fri Jul 03, 2020 11:48
Abstract 49,XXXXY is an X and Y chromosome variation that occurs in 1:85,000 to 1:100,000 live male births. Previous case studies have described boys with this disorder to be shorter than average when compared with boys with only one extra chromosome and with the mean stature in a small cohort reported to range from the seventh to 33rd percentile. The origin behind the possible differences in height between boys with 47,XXY and 49,XXXXY is currently unknown, however one study hypothesized that it...
Thu Jul 02, 2020 21:52
Abstract The etiology of nonimmune hydrops fetalis is extensive and includes genetic disorders. We describe a term‐born female neonate with late onset extensive nonimmune hydrops, that is, polyhydramnios, edema, and congenital bilateral chylothorax. This newborn was successfully treated with repetitive thoracocentesis, total parenteral feeding, octreotide intravenously and finally surgical pleurodesis and corticosteroids. A genetic cause seemed plausible as the maternal history revealed a fatal...
Thu Jul 02, 2020 21:45
Abstract NALCN encodes a sodium ion leak channel expressed in the nervous system that conducts a persistent influx of sodium ions to facilitate action potential formation. Homozygous or compound heterozygous loss of function variants in NALCN cause infantile hypotonia with psychomotor retardation and characteristic facies‐1 (IHPRF1; OMIM 615419). Through exome and Sanger sequencing, we found two siblings of Afro‐Caribbean ancestry who are homozygous for a known NALCN pathogenic variant, p.Arg735Ter,...
Thu Jul 02, 2020 21:24
Abstract We report on a multiply consanguineous Syrian family where two siblings, a boy and a girl, presented with a compilation of symptoms including developmental delay, severe intellectual disability, absent speech, hearing impairment, short stature, subglottic stenosis, increased length of the palpebral fissures, onychodysplasia of index fingers, scoliosis, genu valgum, and malpositioned toes. Two other individuals from the extended family with similar clinical features are also described. Array‐CGH...
Thu Jul 02, 2020 21:15
The Journal of Antibiotics, Published online: 03 July 2020; doi:10.1038/s41429-020-0342-1Cervinomycins C1-4 with cytotoxic and antibacterial activity from Streptomyces sp. CPCC 204980
Fri Jul 03, 2020 03:00
Abstract Classification schemes for reporting thyroid cytology of fine needle aspiration (FNA) of thyroid nodules are largely used in clinical practice, but the level of inter-observer agreement among cytopathologists is poorly acknowledged. The present study aimed to explore the inter-observer agreement among the experienced authors of the 2014 Italian Consensus for Classification and Reporting of Thyroid Cytology (ICCRTC). A stratified randomization was performed in order to...
Fri Jul 03, 2020 03:00
Journal of International Medical Research, Volume 48, Issue 7, July 2020. The Scedosporium apiospermum complex is a group of emerging opportunistic fungal pathogens that affect both immunocompromised and immunocompetent individuals, most commonly via lung infection. Although they are resistant to many antifungal agents, this group of pathogens has a favorable susceptibility profile to azoles, especially voriconazole. Here, we describe the management of S. apiospermum infection in an otherwise healthy...
Thu Jul 02, 2020 05:31
Abstract Males of many species evolved the capability of adjusting their ejaculate phenotype in response to social cues to match the expected mating conditions. When females store sperm for a prolonged time, the expected fitness return of plastic adjustments of ejaculate phenotype may depend on the interval between mating and fertilization. While prolonged female sperm storage (FSS) increases the opportunity for sperm competition, as a consequence of the longer temporal overlap of ejaculates from...
Thu Jul 02, 2020 20:58
Abstract The evolution and diversification of ssRNA plant viruses are often examined under reductionist conditions that ignore potentially much wider biotic interactions. The host range of a plant virus is central to interactions at higher levels that are organised by both fitness and ecological criteria. Here we employ a strategy to minimise sampling biases across distinct plant communities, and combine it with a high throughput sequencing approach to examine the influence of four habitats on the...
Thu Jul 02, 2020 20:36
Summary Despite the high burden of sleep disturbances among the general population, there is limited information on prevalence and impact of poor sleep among injured workers. This study: (a) estimated the prevalence of sleep disturbance following work‐related injury; and (b) examined the longitudinal association between sleep disturbances and disability/functioning, accounting for reciprocal relationships and mental illness. Longitudinal survey data were collected from workers' compensation claimants...
Thu Jul 02, 2020 20:49
Abstract Disturbed sleep during gestation may lead to adverse outcomes for both mother and child. Animal research plays an important role in providing insights into this research field by enabling ethical and methodological requirements that are not possible in humans. Here, we present an overview and discuss the main research findings related to the effects of prenatal sleep deprivation in animal models. Using systematic review approaches, we retrieved 42 articles dealing with some type of sleep...
Thu Jul 02, 2020 20:36
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