Related ArticlesControlled delay of the expulsive phase of foaling affects sympathoadrenal activity and acid base balance of foals in the immediate postnatal phase. Theriogenology. 2019 Nov;139:8-15 Authors: Melchert M, Aurich C, Aurich J, Gautier C, Nagel C Abstract Stress at foaling has been demonstrated to delay birth. In this study, we followed the hypothesis that even a short delay of foaling increases catecholamine and cortisol release in foals,...
Sat Mar 07, 2020 13:14
Related ArticlesAssociation Between Norepinephrine Levels and Abnormal Iron Status in Patients With Chronic Heart Failure: Is Iron Deficiency More Than a Comorbidity? J Am Heart Assoc. 2019 02 19;8(4):e010887 Authors: Moliner P, Enjuanes C, Tajes M, Cainzos-Achirica M, Lupón J, Garay A, Jimenez-Marrero S, Yun S, Farré N, Cladellas M, Díez C, Gonzalez-Costello J, Comin-Colet J Abstract Background Mechanisms underlying iron homeostasis dysregulation in...
Sat Mar 07, 2020 13:14
Related ArticlesScope and efficacy of the broad-spectrum topical antiseptic choline geranate. PLoS One. 2019;14(9):e0222211 Authors: Greene JR, Merrett KL, Heyert AJ, Simmons LF, Migliori CM, Vogt KC, Castro RS, Phillips PD, Baker JL, Lindberg GE, Fox DT, Del Sesto RE, Koppisch AT Abstract Choline geranate (also described as Choline And GEranic acid, or CAGE) has been developed as a novel biocompatible antiseptic material capable of penetrating skin...
Fri Mar 06, 2020 21:47
Abstract Age-related muscle weakness and loss of muscle mass (sarcopenia) is a universal problem in the elderly. Our previous studies indicate that alpha motor neurons (α-MNs) play a critical role in this process. The goal of the current study is to uncover changes in the aging spinal cord that contribute to loss of innervation and the downstream degenerative processes that occur in skeletal muscle. The number of α-MNs is decreased in the spinal cord of wildtype mice during aging,...
Fri Mar 06, 2020 02:00
Related ArticlesInfluence of omega-3 fatty acid and vitamin co-supplementation on metabolic status in gestational diabetes: A meta-analysis of randomized controlled studies. Eur J Obstet Gynecol Reprod Biol. 2020 Feb 26;247:191-197 Authors: Li F, Pei L, Huang G, Ye H Abstract INTRODUCTION: Omega-3 fatty acid and vitamin E or D co-supplementation may be an important approach to improve metabolic status in gestational diabetes, but the results are conflicting....
Sun Mar 08, 2020 15:21
Related ArticlesSOCS3 is a suppressor of γc cytokine signaling and constrains generation of murine Foxp3+ regulatory T cells. Eur J Immunol. 2020 Mar 06;: Authors: Luckey MA, Kim TH, Prakhar P, Keller HR, Crossman A, Choi S, Love PE, Walsh STR, Park JH Abstract SOCS3 is a cytosolic inhibitor of cytokine signaling that suppresses the activation of cytokine receptor-associated JAK kinases. Mechanistically, SOCS3 is recruited to a site in the cytokine receptors...
Sun Mar 08, 2020 13:18
Related ArticlesSelenium and selenoproteins: it's role in regulation of inflammation. Inflammopharmacology. 2020 Mar 06;: Authors: Hariharan S, Dharmaraj S Abstract Selenium is an essential immunonutrient which holds the human's metabolic activity with its chemical bonds. The organic forms of selenium naturally present in human body are selenocysteine and selenoproteins. These forms have a unique way of synthesis and translational coding. Selenoproteins...
Sun Mar 08, 2020 13:18
Related ArticlesEvolutionary and Molecular Characterization of liver-enriched gene 1. Sci Rep. 2020 Mar 06;10(1):4262 Authors: Dang Y, Wang JY, Liu C, Zhang K, Jinrong P, He J Abstract Liver-enriched gene 1 (Leg1) is a newly identified gene with little available functional information. To evolutionarily and molecularly characterize Leg1 genes, a phylogenetic study was first conducted, which indicated that Leg1 is a conserved gene that exists from bacteria...
Sun Mar 08, 2020 13:18
Related ArticlesmRNA Transfection-Induced Activation of Primary Human Monocytes and Macrophages: Dependence on Carrier System and Nucleotide Modification. Sci Rep. 2020 Mar 06;10(1):4181 Authors: Moradian H, Roch T, Lendlein A, Gossen M Abstract Monocytes and macrophages are key players in maintaining immune homeostasis. Identifying strategies to manipulate their functions via gene delivery is thus of great interest for immunological research and biomedical...
Sun Mar 08, 2020 13:18
Related ArticlesKidney residency of VISTA-positive macrophages accelerates repair from ischemic injury. Kidney Int. 2019 Dec 17;: Authors: Park JG, Lee CR, Kim MG, Kim G, Shin HM, Jeon YH, Yang SH, Kim DK, Joo KW, Choi EY, Kim HR, Kwak C, Kim YS, Choi M, Lee DS, Han SS Abstract Tissue-resident macrophages have unique tissue-specific functions in maintaining homeostasis and resolving inflammation. However, the repair role and relevant molecules of kidney-resident...
Sun Mar 08, 2020 13:18
Related ArticlesMetatranscriptomic analysis to define the Secrebiome, and 16S rRNA profiling of the gut microbiome in obesity and metabolic syndrome of Mexican children. Microb Cell Fact. 2020 Mar 06;19(1):61 Authors: Gallardo-Becerra L, Cornejo-Granados F, García-López R, Valdez-Lara A, Bikel S, Canizales-Quinteros S, López-Contreras BE, Mendoza-Vargas A, Nielsen H, Ochoa-Leyva A Abstract BACKGROUND: In the last decade, increasing evidence has shown...
Sun Mar 08, 2020 13:18
83 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: human homeostasis These pubmed results were generated on 2020/03/07PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Sat Mar 07, 2020 14:50
45 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: human homeostasis These pubmed results were generated on 2020/03/06PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Fri Mar 06, 2020 22:32
Related ArticlesRx risk or resistance? Psychotropic medication use in relation to physiological and psychosocial functioning of psychiatric hospital workers. Psychoneuroendocrinology. 2020 Feb 28;115:104634 Authors: Kerr P, Lupien S, Juster RP Abstract To avoid methodological biases, psychoneuroendocrine studies have generally excluded psychotropic medication users. In workplace stress research, this has limited our ability to understand how psychotropic...
Sun Mar 08, 2020 15:08
Related ArticlesResting-state "physiological networks". Neuroimage. 2020 Mar 04;:116707 Authors: Chen J, Lewis L, Chang C, Tian Q, Fultz N, Ohringer N, Rosen B, Polimeni J Abstract Slow changes in systemic brain physiology can elicit large fluctuations in fMRI time series, which manifest as structured spatial patterns of temporal correlations between distant brain regions. Here, we investigated whether such "physiological networks"-sets of segregated...
Sun Mar 08, 2020 15:08
Related ArticlesIntraoperative electrophysiological mapping of medial frontal motor areas and functional outcomes. World Neurosurg. 2020 Mar 04;: Authors: Shibata S, Yamao Y, Kunieda T, Inano R, Nakae T, Nishida S, Inada T, Takahashi Y, Kikuchi T, Arakawa Y, Yoshida K, Matsumoto R, Ikeda A, Mima T, Miyamoto S Abstract OBJECTIVE: To propose a method for intraoperative mapping and monitoring of the medial frontal motor areas (MFMA). METHODS: We...
Sun Mar 08, 2020 15:08
Related ArticlesTanshinone IIA pretreatment promotes cell survival in human lung epithelial cells under hypoxia via AP-1-Nrf2 transcription factor. Cell Stress Chaperones. 2020 Mar 06;: Authors: Yadav S, Singh M, Singh SN, Kumar B Abstract Activator protein-1 (AP-1) plays a decisive role in cell proliferation, apoptosis, and inflammation under hypoxia; thus, AP-1 subunits or dimers could be modulated for a desired phenomenon in a cell using a suitable...
Sun Mar 08, 2020 13:12
Related ArticlesAdenovirus Biodistribution is Modified in Sensitive Animals Compared to Naïve Animals. Mol Biotechnol. 2020 Mar 06;: Authors: Sandoval-Rodríguez A, Mena-Enriquez M, García-Bañuelos J, Salazar-Montes A, Fafutis-Morris M, Vázquez-Del Mercado M, Santos-García A, Armendariz-Borunda J Abstract Pre-existing immune response against adenovirus could diminish transgene expression efficiency when Ad is employed in humans as gene therapy vector....
Sun Mar 08, 2020 13:12
Related ArticlesCardiac autonomic modulation in type 1 diabetes during exercise-heat stress. Acta Diabetol. 2020 Mar 06;: Authors: Macartney MJ, Notley SR, Herry CL, Seely AJE, Sigal RJ, Kenny GP Abstract AIMS: Cardiac autonomic modulation, as assessed by heart rate variability (HRV), is independently attenuated by both type 1 diabetes (T1D) and exercise-heat stress, although their combined effects remain unclear. We therefore assessed HRV during exercise-heat...
Sun Mar 08, 2020 13:12
Related ArticlesTranscriptional diversity and bioenergetic shift in human breast cancer metastasis revealed by single-cell RNA sequencing. Nat Cell Biol. 2020 Mar;22(3):310-320 Authors: Davis RT, Blake K, Ma D, Gabra MBI, Hernandez GA, Phung AT, Yang Y, Maurer D, Lefebvre AEYT, Alshetaiwi H, Xiao Z, Liu J, Locasale JW, Digman MA, Mjolsness E, Kong M, Werb Z, Lawson DA Abstract Although metastasis remains the cause of most cancer-related mortality, mechanisms...
Sun Mar 08, 2020 13:12
Related ArticlesDiet influences the functions of the human intestinal microbiome. Sci Rep. 2020 Mar 06;10(1):4247 Authors: De Angelis M, Ferrocino I, Calabrese FM, De Filippis F, Cavallo N, Siragusa S, Rampelli S, Di Cagno R, Rantsiou K, Vannini L, Pellegrini N, Lazzi C, Turroni S, Lorusso N, Ventura M, Chieppa M, Neviani E, Brigidi P, O'Toole PW, Ercolini D, Gobbetti M, Cocolin L Abstract Gut microbes programme their metabolism to suit intestinal conditions...
Sun Mar 08, 2020 13:12
Related ArticlesRobust and replicable measurement for prepulse inhibition of the acoustic startle response. Mol Psychiatry. 2020 Mar 06;: Authors: Miller EA, Kastner DB, Grzybowski MN, Dwinell MR, Geurts AM, Frank LM Abstract Measuring animal behavior in the context of experimental manipulation is critical for modeling, and understanding neuropsychiatric disease. Prepulse inhibition of the acoustic startle response (PPI) is a behavioral phenomenon studied...
Sun Mar 08, 2020 13:12
Related ArticlesThe association between breastmilk oligosaccharides and faecal microbiota in healthy breastfed infants at two, six, and twelve weeks of age. Sci Rep. 2020 Mar 06;10(1):4270 Authors: Borewicz K, Gu F, Saccenti E, Hechler C, Beijers R, de Weerth C, van Leeuwen SS, Schols HA, Smidt H Abstract Several factors affect gut microbiota development in early life, among which breastfeeding plays a key role. We followed 24 mother-infant pairs to...
Sun Mar 08, 2020 13:12
Related ArticlesEffects of natural polyphenol-rich pomegranate juice on the acute and delayed response of Homocysteine and steroidal hormones following weightlifting exercises: a double-blind, placebo-controlled trial. J Int Soc Sports Nutr. 2020 Mar 06;17(1):15 Authors: Ammar A, MounaTurki, Trabelsi K, Bragazzi NL, Boukhris O, Bouaziz M, Ayadi F, El Abed K, Driss T, Souissi N, Chtourou H, Bailey SJ, Hoekelmann A Abstract BACKGROUND: Maximal strength-speed...
Sun Mar 08, 2020 13:12
Related ArticlesApproaches to overcome flow cytometry limitations in the analysis of cells from veterinary relevant species. BMC Vet Res. 2020 Mar 06;16(1):83 Authors: Hunka J, Riley JT, Debes GF Abstract BACKGROUND: Flow cytometry is a powerful tool for the multiparameter analysis of leukocyte subsets on the single cell level. Recent advances have greatly increased the number of fluorochrome-labeled antibodies in flow cytometry. In particular, an increase...
Sun Mar 08, 2020 13:12
Related ArticlesSUMOylation in Human Pathogenic Fungi: Role in Physiology and Virulence. J Fungi (Basel). 2020 Mar 04;6(1): Authors: Sahu MS, Patra S, Kumar K, Kaur R Abstract The small ubiquitin-related modifier (SUMO) protein is an important component of the post-translational protein modification systems in eukaryotic cells. It is known to modify hundreds of proteins involved in diverse cellular processes, ranging from nuclear pore dynamics to signal...
Sun Mar 08, 2020 13:12
Related ArticlesResponse to Stimulations Inducing Circadian Rhythm in Human Induced Pluripotent Stem Cells. Cells. 2020 Mar 04;9(3): Authors: Kaneko H, Kaitsuka T, Tomizawa K Abstract Regenerative medicine and disease modeling are expanding rapidly, through the development of human-induced pluripotent stem cells (hiPSCs). Many exogeneous supplements are often used for the directed differentiation of hiPSCs to specific lineages, such as chemicals and...
Sun Mar 08, 2020 13:12
Related ArticlesA Non-Invasive Investigation into the Prevalence of Higher than Normal Blood Pressure, Hypertension and the Association between Blood Pressure and Body Weight in Male and Female Adolescents in the Polokwane Local Municipality, Limpopo-South Africa: A Cross-Sectional Study. Children (Basel). 2020 Mar 04;7(3): Authors: Raphadu TT, Staden MV, Dibakwane WM, Monyeki KD Abstract BACKGROUND: Hypertension (HT) is one of the greatest non-communicable...
Sun Mar 08, 2020 13:12
262 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: human physiology These pubmed results were generated on 2020/03/07PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Sat Mar 07, 2020 15:45
262 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: human physiology These pubmed results were generated on 2020/03/07PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Sat Mar 07, 2020 13:48
157 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: human physiology These pubmed results were generated on 2020/03/06PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Fri Mar 06, 2020 22:11
977 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: medical science These pubmed results were generated on 2020/03/08PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Sun Mar 08, 2020 14:27
977 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: medical science These pubmed results were generated on 2020/03/08PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Sun Mar 08, 2020 12:27
5802 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: medical science These pubmed results were generated on 2020/03/07PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Sat Mar 07, 2020 14:36
2868 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: medical science These pubmed results were generated on 2020/03/06PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Fri Mar 06, 2020 22:40
Related ArticlesGenetic and Genomic Advances in Developmental Models: Applications for Nutrition Research. Adv Nutr. 2020 Mar 05;: Authors: Chowanadisai W, Hart MD, Strong MD, Graham DM, Rucker RB, Smith BJ, Keen CL, Messerli MA Abstract There is increasing appreciation that dietary components influence and interact with genes important to metabolism. How such influences impact developmental regulation and programming or risks of chronic diseases remains...
Sat Mar 07, 2020 01:04
Related ArticlesThe Effects of Diets Enriched in Monounsaturated Oleic Acid on the Management and Prevention of Obesity: a Systematic Review of Human Intervention Studies. Adv Nutr. 2020 Mar 05;: Authors: Tutunchi H, Ostadrahimi A, Saghafi-Asl M Abstract Obesity is associated with an increased risk of several major noncommunicable diseases, and is an important public health concern globally. Dietary fat content is a major contributor to the increase...
Sat Mar 07, 2020 01:04
Related ArticlesPerspective: Time to Resolve Confusion on Folate Amounts, Units, and Forms in Prenatal Supplements. Adv Nutr. 2020 Mar 05;: Authors: Saldanha LG, Dwyer JT, Haggans CJ, Mills JL, Potischman N Abstract Folate-containing prenatal supplements are commonly consumed in the United States, but inconsistencies in units of measure and chemical forms pose challenges for providing authoritative advice on recommended amounts. New regulations require...
Sat Mar 07, 2020 01:04
Related ArticlesPyBSASeq: a simple and effective algorithm for bulked segregant analysis with whole-genome sequencing data. BMC Bioinformatics. 2020 Mar 06;21(1):99 Authors: Zhang J, Panthee DR Abstract BACKGROUND: Bulked segregant analysis (BSA), coupled with next-generation sequencing, allows the rapid identification of both qualitative and quantitative trait loci (QTL), and this technique is referred to as BSA-Seq here. The current SNP index method...
Sun Mar 08, 2020 12:02
Related ArticlesGamevar.f90: a software package for calculating individual gametic diversity. BMC Bioinformatics. 2020 Mar 06;21(1):100 Authors: de Abreu Santos DJ, Cole JB, Liu GE, VanRaden PM, Ma L Abstract BACKGROUND: Traditional selection in livestock and crops focuses on additive genetic values or breeding values of the individuals. While traditional selection utilizes variation between individuals, differences between gametes within individuals...
Sun Mar 08, 2020 12:02
Related ArticlesCNV Radar: an improved method for somatic copy number alteration characterization in oncology. BMC Bioinformatics. 2020 Mar 06;21(1):98 Authors: Soong D, Stratford J, Avet-Loiseau H, Bahlis N, Davies F, Dispenzieri A, Sasser AK, Schecter JM, Qi M, Brown C, Jones W, Keats JJ, Auclair D, Chiu C, Powers J, Schaffer M Abstract BACKGROUND: Cancer associated copy number variation (CNV) events provide important information for identifying patient...
Sun Mar 08, 2020 12:02
Related ArticlesComparative study of whole exome sequencing-based copy number variation detection tools. BMC Bioinformatics. 2020 Mar 05;21(1):97 Authors: Zhao L, Liu H, Yuan X, Gao K, Duan J Abstract BACKGROUND: With the rapid development of whole exome sequencing (WES), an increasing number of tools are being proposed for copy number variation (CNV) detection based on this technique. However, no comprehensive guide is available for the use of these...
Sat Mar 07, 2020 14:32
Related ArticlesFamily reunion via error correction: an efficient analysis of duplex sequencing data. BMC Bioinformatics. 2020 Mar 04;21(1):96 Authors: Stoler N, Arbeithuber B, Povysil G, Heinzl M, Salazar R, Makova KD, Tiemann-Boege I, Nekrutenko A Abstract BACKGROUND: Duplex sequencing is the most accurate approach for identification of sequence variants present at very low frequencies. Its power comes from pooling together multiple descendants of...
Fri Mar 06, 2020 22:54
Related ArticlesIntroducing career skills for dental students as an undergraduate course at the University of Szeged, Hungary. BMC Med Educ. 2020 Mar 06;20(1):68 Authors: Szabó RM, Davis JM, Antal M Abstract BACKGROUND: In the last three decades there is a growing recognition in the dental profession that dental education must go beyond teaching the technicalities of dentistry and include professionalism and communication skills that the future dentist...
Sun Mar 08, 2020 12:54
Related ArticlesEvidence to support the early introduction of laparoscopic suturing skills into the surgical training curriculum. BMC Med Educ. 2020 Mar 06;20(1):70 Authors: Tang B, Zhang L, Alijani A Abstract BACKGROUND: The objectives of this study were to investigate the relationship between the acquisition of laparoscopic suturing skills and other operative laparoscopic skills and to provide evidence to determine ideal time and duration to introduce...
Sun Mar 08, 2020 12:54
Related ArticlesConfidence and motivation to help those with a mental health problem: experiences from a study of nursing students completing mental health first aid (MHFA) training. BMC Med Educ. 2020 Mar 06;20(1):69 Authors: Crawford G, Burns S Abstract BACKGROUND: Those studying nursing are at greater risk for developing mental health problems than other tertiary students. Mental Health First Aid (MHFA) training may assist students to support peers...
Sun Mar 08, 2020 12:54
Related ArticlesHow does video case-based learning influence clinical decision-making by midwifery students? An exploratory study. BMC Med Educ. 2020 Mar 06;20(1):67 Authors: Nunohara K, Imafuku R, Saiki T, Bridges SM, Kawakami C, Tsunekawa K, Niwa M, Fujisaki K, Suzuki Y Abstract BACKGROUND: Clinical decision-making skills are essential for providing high-quality patient care. To enhance these skills, many institutions worldwide use case-based learning...
Sun Mar 08, 2020 12:54
Related ArticlesThe development of a robotic gynaecological surgery training curriculum and results of a delphi study. BMC Med Educ. 2020 Mar 04;20(1):66 Authors: Ismail A, Wood M, Ind T, Gul N, Moss E Abstract BACKGROUND: Technology for minimal access surgery is rapidly progressing in all surgical specialities including Gynaecology. As robotic surgery becomes established in increasing numbers of hospitals, there is no set curriculum for training in...
Fri Mar 06, 2020 22:45
Related ArticlesSocial ties influence teamwork when managing clinical emergencies. BMC Med Educ. 2020 Mar 04;20(1):63 Authors: Rasmussen MB, Tolsgaard MG, Dieckmann P, Østergaard D, White J, Plenge P, Ringsted CV Abstract BACKGROUND: Our current understanding of medical team competence is traditionally influenced by an individualistic perspective focusing on individual team members' knowledge, skills as well as on effective communication within the team....
Fri Mar 06, 2020 22:45
Related ArticlesPerceptions of scheduled vs. unscheduled directly observed visits in an internal medicine residency outpatient clinic. BMC Med Educ. 2020 Mar 04;20(1):64 Authors: Rea J, Stephenson C, Leasure E, Vaa B, Halvorsen A, Huber J, Bonnes S, Hafdahl L, Post J, Wingo M Abstract INTRODUCTION: Learners may subconsciously change their behavior once they know they are being observed, and this Hawthorne effect should be considered when designing assessments...
Fri Mar 06, 2020 22:45
Related ArticlesEffects of a single interprofessional simulation session on medical and nursing students' attitudes toward interprofessional learning and professional identity: a questionnaire study. BMC Med Educ. 2020 Mar 04;20(1):65 Authors: Burford B, Greig P, Kelleher M, Merriman C, Platt A, Richards E, Davidson N, Vance G Abstract BACKGROUND: Participation in simulation-based interprofessional education (sim-IPE) may affect students' attitudes towards...
Fri Mar 06, 2020 22:45
Related ArticlesSelf-management practice, associated factors and its relationship with health literacy and patient activation among multi-morbid COPD patients from rural Nepal. BMC Public Health. 2020 Mar 06;20(1):300 Authors: Yadav UN, Lloyd J, Hosseinzadeh H, Baral KP, Bhatta N, Harris MF Abstract BACKGROUND: Chronic Obstructive Pulmonary Disease (COPD) is a progressive and debilitating condition that affects individuals' quality of life. COPD self-management...
Sun Mar 08, 2020 12:03
Related ArticlesPrevalence of metabolic syndrome among ethnic groups in China. BMC Public Health. 2020 Mar 06;20(1):297 Authors: Qin X, Qiu L, Tang G, Tsoi MF, Xu T, Zhang L, Qi Z, Zhu G, Cheung BMY Abstract BACKGROUND: Metabolic syndrome (MetS) is common in China, which has a multi-ethnic population of 1·3 billion. We set out to determine the prevalence of MetS and its components in different ethnic groups. METHODS: This nationwide cross-sectional...
Sun Mar 08, 2020 12:03
Related ArticlesFactors associated with loss-to-follow-up of HIV-positive mothers and their infants enrolled in HIV care clinic: A qualitative study. BMC Public Health. 2020 Mar 06;20(1):298 Authors: Mpinganjira S, Tchereni T, Gunda A, Mwapasa V Abstract BACKGROUND: In Malawi, loss to follow-up (LTFU) of HIV-positive pregnant and postpartum women on Option B+ regimen greatly contributes to sub-optimal retention, estimated to be 74% at 12 months postpartum....
Sun Mar 08, 2020 12:03
Related ArticlesApproaches, barriers, and facilitators to abortion-related work in U.S. health departments: perspectives of maternal and child heath and family planning professionals. BMC Public Health. 2020 Mar 06;20(1):299 Authors: Berglas NF, Wingo E, Woodruff K, Roberts SCM Abstract BACKGROUND: Public health agencies in the United States have engaged in abortion-related activities for nearly 50 years. Prior research indicates that, while most state...
Sun Mar 08, 2020 12:03
Related ArticlesKnowledge about cervical cancer and HPV immunization dropout rate among Brazilian adolescent girls and their guardians. BMC Public Health. 2020 Mar 06;20(1):301 Authors: Santos ACDS, Silva NNT, Carneiro CM, Coura-Vital W, Lima AA Abstract BACKGROUND: Infections with Human Papillomavirus (HPV) are the main cause of cervical cancer. Since 2014, the HPV vaccine was introduced in the Brazilian National Vaccination Calendar. The purpose of...
Sun Mar 08, 2020 12:03
Related ArticlesPotential effect of different nutritional labels on food choices among mothers: a study protocol. BMC Public Health. 2020 Mar 06;20(1):294 Authors: Seyedhamzeh S, Nedjat S, Hosseini H, Shakibazedeh E, Viera AJ, Dorosty Motlagh A Abstract BACKGROUND: The prevalence of non-communicable diseases (NCDs) is increasing in the world. Healthy food choice and adequate physical activity are key factors in preventing NCDs. Food labeling is a strategy...
Sat Mar 07, 2020 14:39
Related ArticlesBMI modified the association of current smoking with the incidence of hypertension in Chinese population: a 22-year cohort study. BMC Public Health. 2020 Mar 06;20(1):295 Authors: Yao F, Liu W, Zhao R, Li G, Huang X, Chen Y Abstract BACKGROUND: There was little known on how the interaction effect between obesity and current smoking affected the incidence of hypertension. The aim of this study was to investigate how body mass index (BMI)...
Sat Mar 07, 2020 14:39
Related ArticlesKnowledge, attitudes and practices towards viral haemorrhagic fevers amongst healthcare workers in urban and rural public healthcare facilities in the N'zérékoré prefecture, Guinea: a cross-sectional study. BMC Public Health. 2020 Mar 06;20(1):296 Authors: Raab M, Pfadenhauer LM, Millimouno TJ, Hoelscher M, Froeschl G Abstract BACKGROUND: The 2013-2016 Ebola epidemic in West Africa began in Guinea's Forest region, a region now considered...
Sat Mar 07, 2020 14:39
Related ArticlesPrevalence and associated factors of hypertension among adults in Gadarif in eastern Sudan: a community-based study. BMC Public Health. 2020 Mar 06;20(1):291 Authors: Omar SM, Musa IR, Osman OE, Adam I Abstract BACKGROUND: Hypertension is becoming an increasingly common health issue worldwide, especially in countries in Sub-Saharan Africa. Hypertension is the leading risk factor for premature death and disability worldwide, and it is...
Sat Mar 07, 2020 14:39
Related ArticlesCulture competence and mental health across different immigrant and refugee groups. BMC Public Health. 2020 Mar 06;20(1):292 Authors: Oppedal B, Keles S, Cheah C, Røysamb E Abstract BACKGROUND: Over the last decades, due to high rates of immigration, many high-income countries have witnessed demographic shifts towards more cultural diversity in the population. Socio-economic deprivation and traumatic experiences pre-migration contribute...
Sat Mar 07, 2020 14:39
Related ArticlesThe association between PM2.5 exposure and suicidal ideation: a prefectural panel study. BMC Public Health. 2020 Mar 06;20(1):293 Authors: Chen Y, He G, Chen B, Wang S, Ju G, Ge T Abstract BACKGROUND: Suicidal ideation is subject to serious underestimation among existing public health studies. While numerous factors have been recognized in affecting suicidal thoughts and behaviors (STB), the associated environmental risks have been poorly...
Sat Mar 07, 2020 14:39
Related ArticlesEffects of humorous interventions on the willingness to donate organs: a quasi-experimental study in the context of medical cabaret. BMC Public Health. 2020 Mar 04;20(1):288 Authors: Heitland L, von Hirschhausen E, Fischer F Abstract BACKGROUND: It has been shown that fears and misconceptions negatively affect the willingness to donate organs. Empirical studies have examined health communication strategies that serve to debunk these fears....
Fri Mar 06, 2020 23:03
Related ArticlesConversations about alcohol in healthcare - cross-sectional surveys in the Netherlands and Sweden. BMC Public Health. 2020 Mar 04;20(1):283 Authors: Abidi L, Nilsen P, Karlsson N, Skagerström J, O'Donnell A Abstract BACKGROUND: This study evaluated and compared the extent, duration, contents, experiences and effects of alcohol conversations in healthcare in the Netherlands and Sweden in 2017. METHODS: Survey data in the Netherlands...
Fri Mar 06, 2020 23:03
Related ArticlesAdiposity reduces the risk of osteoporosis in Chinese rural population: the Henan rural cohort study. BMC Public Health. 2020 Mar 04;20(1):285 Authors: Tian H, Pan J, Qiao D, Dong X, Li R, Wang Y, Tu R, Abdulai T, Liu X, Hou J, Zhang G, Wang C Abstract BACKGROUND: Adiposity plays a crucial role in the risk of osteoporosis. However, the impact of body fat distribution on the skeleton is contentious. The study was designed to explore the...
Fri Mar 06, 2020 23:03
Related ArticlesA randomized controlled trial of an educational intervention to promote oral and dental health of patients with type 2 diabetes mellitus. BMC Public Health. 2020 Mar 04;20(1):287 Authors: Malekmahmoodi M, Shamsi M, Roozbahani N, Moradzadeh R Abstract BACKGROUND: Diabetes is the most prevalent disease resulted from metabolic disorders. This study aimed to investigate the effect of training based on health belief model (HBM) on oral hygiene-related...
Fri Mar 06, 2020 23:03
Related ArticlesAdolescent multiple risk behaviours cluster by number of risks rather than distinct risk profiles in the ALSPAC cohort. BMC Public Health. 2020 Mar 04;20(1):290 Authors: Wright C, Heron J, Campbell R, Hickman M, Kipping RR Abstract BACKGROUND: Experimentation with new behaviours during adolescence is normal. However, engagement in two or more risk behaviours, termed multiple risk behaviours is associated with socioeconomic disadvantage...
Fri Mar 06, 2020 23:03
Related ArticlesSocio-economic inequalities in the multiple dimensions of access to healthcare: the case of South Africa. BMC Public Health. 2020 Mar 04;20(1):289 Authors: Gordon T, Booysen F, Mbonigaba J Abstract BACKGROUND: The National Development Plan (NDP) strives that South Africa, by 2030, in pursuit of Universal Health Coverage (UHC) achieve a significant shift in the equity of health services provision. This paper provides a diagnosis of the...
Fri Mar 06, 2020 23:03
Related ArticlesAre countries' self-reported assessments of their capacity for infectious disease control reliable? Associations among countries' self-reported international health regulation 2005 capacity assessments and infectious disease control outcomes. BMC Public Health. 2020 Mar 04;20(1):282 Authors: Tsai FJ, Tipayamongkholgul M Abstract BACKGROUND: This study aimed to evaluate associations among countries' self-reported International Health Regulation...
Fri Mar 06, 2020 23:03
Related ArticlesEfficacy and cultural appropriateness of psychosocial interventions for paediatric burn patients and caregivers: a systematic review. BMC Public Health. 2020 Mar 04;20(1):284 Authors: Williams HM, Hunter K, Clapham K, Ryder C, Kimble R, Griffin B Abstract BACKGROUND: Paediatric burns are highly painful and traumatising injuries that are overrepresented among Aboriginal and Torres Strait Islander people. Paediatric burn patients' pain...
Fri Mar 06, 2020 23:03
Related ArticlesRisk factor analysis of insufficient fluid intake among urban adults in Wuxi, China: a classification and regression tree analysis. BMC Public Health. 2020 Mar 04;20(1):286 Authors: Zheng H, Fei J, Zhang L, Zhou W, Ding Z, Hu W Abstract BACKGROUND: Dehydration due to insufficient fluid intake (IFI) is detrimental to health. This cross-sectional study aimed to assess the fluid intake of urban adults in Wuxi, China, and to identify potential...
Fri Mar 06, 2020 23:03
Related ArticlesCorrection: Strategies occupational therapists employ to facilitate work-related transitions for persons with hand injuries: a study protocol for a scoping review. BMJ Open. 2020 Mar 06;10(3):e027402corr2 Authors: PMID: 32144173 [PubMed - as supplied by publisher]
Sun Mar 08, 2020 12:59
Related Articles'I can do this': a qualitative exploration of acceptability and experiences of a physical activity behaviour change intervention in people with multiple sclerosis in the UK. BMJ Open. 2020 Mar 06;10(3):e029831 Authors: Fortune J, Norris M, Stennett A, Kilbride C, Lavelle G, Hendrie W, de Souza L, Abdul M, Brewin D, David L, Anokye N, Victor C, Ryan JM Abstract OBJECTIVES: The purpose of this study was to explore the experiences of people...
Sun Mar 08, 2020 12:59
23 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: "BMJ Open"[jour] These pubmed results were generated on 2020/03/07PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Sat Mar 07, 2020 14:30
Related ArticlesHow valid are projections of the future prevalence of diabetes? Rapid reviews of prevalence-based and Markov chain models and comparisons of different models' projections for England. BMJ Open. 2020 Mar 03;10(3):e033483 Authors: Bevan G, De Poli C, Keng MJ, Raine R Abstract OBJECTIVES: To examine validity of prevalence-based models giving projections of prevalence of diabetes in adults, in England and the UK, and of Markov chain models...
Fri Mar 06, 2020 22:11
Related ArticlesAnticipated impacts of Brexit scenarios on UK food prices and implications for policies on poverty and health: a structured expert judgement approach. BMJ Open. 2020 Mar 03;10(3):e032376 Authors: Barons MJ, Aspinall W Abstract INTRODUCTION: Food insecurity is associated with increased risk for several health conditions and with poor chronic disease management. Key determinants for household food insecurity are income and food costs. Whereas...
Fri Mar 06, 2020 22:11
Related ArticlesDirect non-medical and indirect costs of diabetes and its associated complications in Vietnam: an estimation using national health insurance claims from a cross-sectional survey. BMJ Open. 2020 Mar 03;10(3):e032303 Authors: Kieu TTM, Trinh HN, Pham HTK, Nguyen TB, Ng JYS Abstract OBJECTIVE: The prevalence of diabetes in Vietnam has increased from 2.5% in 2007 to 5.5% in 2017, but the burden of direct non-medical and indirect costs is...
Fri Mar 06, 2020 22:11
Related ArticlesDo employer-sponsored health insurance schemes affect the utilisation of medically trained providers and out-of-pocket payments among ready-made garment workers? A case-control study in Bangladesh. BMJ Open. 2020 Mar 03;10(3):e030298 Authors: Ahmed S, Sarker AR, Sultana M, Roth F, Mahumud RA, Kamruzzaman M, Hasan MZ, Mirelman AJ, Islam Z, Niessen LW, Rehnberg C, Khan AA, Gyr N, Khan JAM Abstract OBJECTIVE: We estimated the effect of an...
Fri Mar 06, 2020 22:11
Related ArticlesSilver nanoparticle synthesis in human ferritin by photochemical reduction. J Inorg Biochem. 2020 Feb 01;206:111016 Authors: Moglia I, Santiago M, Soler M, Olivera-Nappa A Abstract Ferritin is a globular hollow protein that acts as the major iron storage protein across living organisms. The 8 nm-diameter internal cavity of ferritin has been used as a nanoreactor for the synthesis of various metallic nanoparticles different to iron oxides....
Sat Mar 07, 2020 16:12
Related ArticlesSupplementation with Seabuckthorn Oil Augmented in 16:1n-7t Increases Serum Trans-Palmitoleic Acid in Metabolically Healthy Adults: A Randomized Crossover Dose-Escalation Study. J Nutr. 2020 Mar 06;: Authors: Huang NK, Matthan NR, Galluccio JM, Shi P, Lichtenstein AH, Mozaffarian D Abstract BACKGROUND: In animal models cis-palmitoleic acid (9-hexadecenoic acid; 16:1n-7c), a lipokine, improves insulin sensitivity, inflammation, and lipoprotein...
Sat Mar 07, 2020 13:00
Related ArticlesProtein Requirements of Elderly Chinese Adults Are Higher than Current Recommendations. J Nutr. 2020 Mar 06;: Authors: Mao D, Chen F, Wang R, Bai P, Zhang Y, Zhao W, Chen J, Yang L, Yang X, Li M Abstract BACKGROUND: Due to a lack of research data on the protein requirements of the elderly in China, the estimated average requirement (EAR) and the recommended nutrient intake (RNI) of protein in the elderly remain the same as those in young...
Sat Mar 07, 2020 13:00
Related ArticlesThe "Super-Child" Approach Is Applied To Estimate Retinol Kinetics and Vitamin A Total Body Stores in Mexican Preschoolers. J Nutr. 2020 Mar 05;: Authors: Lopez-Teros V, Ford JL, Green MH, Monreal-Barraza B, García-Miranda L, Tanumihardjo SA, Valencia ME, Astiazaran-Garcia H Abstract BACKGROUND: Retinol isotope dilution (RID) and model-based compartmental analysis are recognized techniques for assessing vitamin A (VA) status. Recent studies...
Fri Mar 06, 2020 22:30
Related ArticlesDecreasing the Ratio of Dietary Linoleic to α-Linolenic Acid from 10 to 4 by Changing Only the Former Does Not Prevent Adiposity or Bone Deterioration in Obese Mice. J Nutr. 2020 Mar 05;: Authors: Cao JJ, Gregoire BR, Michelsen KG, Picklo MJ Abstract BACKGROUND: Linoleic acid (LA; 18:2n-6) has been considered to promote low-grade chronic inflammation and adiposity. Studies show adiposity and inflammation are inversely associated with...
Fri Mar 06, 2020 22:30
Related ArticlesAn Amino Acid-Based Oral Rehydration Solution Regulates Radiation-Induced Intestinal Barrier Disruption in Mice. J Nutr. 2020 Mar 04;: Authors: Gupta R, Yin L, Grosche A, Lin S, Xu X, Guo J, Vaught LA, Okunieff PG, Vidyasagar S Abstract BACKGROUND: Radiotherapy inadvertently affects gastrointestinal (GI) epithelial cells, causing intestinal barrier disruption and increased permeability. OBJECTIVE: We examined the effect of amino...
Fri Mar 06, 2020 22:30
Related ArticlesTotal Water-Soluble Choline Concentration Does Not Differ in Milk from Vegan, Vegetarian, and Nonvegetarian Lactating Women. J Nutr. 2020 Mar 01;150(3):512-517 Authors: Perrin MT, Pawlak R, Allen LH, Hampel D Abstract BACKGROUND: Choline is an essential nutrient for brain growth and other processes in the developing neonate. The impact of a maternal plant-based diet on the choline composition of breast milk is unknown. OBJECTIVE:...
Fri Mar 06, 2020 22:30
Related ArticlesReply to A Wittekind. J Nutr. 2020 Mar 01;150(3):645-646 Authors: van Eekelen EW, Beulens JWJ, Rosendaal FR, de Mutsert R PMID: 32133523 [PubMed - in process]
Fri Mar 06, 2020 22:30
Related ArticlesSugar-Sweetened Beverages Are Not Associated with Increased Liver Fat Content in Middle-Aged Men and Women. J Nutr. 2020 Mar 01;150(3):644 Authors: Wittekind AL PMID: 32133522 [PubMed - in process]
Fri Mar 06, 2020 22:30
Related ArticlesIdentification of Milk and Cheese Intake Biomarkers in Healthy Adults Reveals High Interindividual Variability of Lewis System-Related Oligosaccharides. J Nutr. 2020 Mar 04;: Authors: Pimentel G, Burnand D, Münger LH, Pralong FP, Vionnet N, Portmann R, Vergères G Abstract BACKGROUND: The use of biomarkers of food intake (BFIs) in blood and urine has shown great promise for assessing dietary intake and complementing traditional dietary...
Fri Mar 06, 2020 22:30
Related ArticlesDifferences in Diet Quality among Multiple US Racial/Ethnic Groups from the Mediators of Atherosclerosis in South Asians Living in America (MASALA) Study and the Multi-Ethnic Study of Atherosclerosis (MESA). J Nutr. 2020 Mar 04;: Authors: Rodriguez LA, Jin Y, Talegawkar SA, Otto MCO, Kandula NR, Herrington DM, Kanaya AM Abstract BACKGROUND: Diet quality is an important risk factor for type 2 diabetes (T2D) and cardiovascular disease (CVD)....
Fri Mar 06, 2020 22:30
Related ArticlesAdherence to the Australian Dietary Guidelines Is Not Associated with Brain Structure or Cognitive Function in Older Adults. J Nutr. 2020 Mar 04;: Authors: Zabetian-Targhi F, Srikanth VK, Beare R, Moran C, Wang W, Breslin M, Smith KJ, Callisaya ML Abstract BACKGROUND: Cognitive dysfunction is common in older adults, particularly in those with type 2 diabetes (T2D). Higher adherence to the Dietary Guidelines for Americans is associated...
Fri Mar 06, 2020 22:30
Related ArticlesSpike-wave discharges in absence epilepsy: Segregation of electrographic components reveals distinct pathways of seizure activity. J Physiol. 2020 Mar 07;: Authors: Terlau J, Yang JW, Khastkhodaei Z, Seidenbecher T, Luhmann HJ, Pape HC, Lüttjohann A Abstract KEY POINTS: The major electrophysiological hallmark of absence seizures are spike and wave discharges, consisting of a sharp spike- and a slow wave component. In a widely accepted...
Sun Mar 08, 2020 14:03
Related ArticlesLimited capacity for ipsilateral secondary motor areas to support hand function post-stroke. J Physiol. 2020 Mar 07;: Authors: Wilkins KB, Yao J, Owen M, Karbasforoushan H, Carmona C, Dewald JPA Abstract KEY POINTS: Ipsilateral-projecting corticobulbar pathways, originating primarily from secondary motor areas, innervate the proximal and even distal portions, but branch more extensively at the spinal cord It is currently unclear to what...
Sun Mar 08, 2020 14:03
Related ArticlesFrom bedside-to-bench: What disease-associated variants are teaching us about the NMDA receptor. J Physiol. 2020 Mar 07;: Authors: Amin JB, Moody GR, Wollmuth LP Abstract NMDA receptors (NMDARs) are glutamate-gated ion channels that contribute to nearly all brain processes. Not surprisingly then, genetic variations in the genes encoding NMDAR subunits can be associated with neurodevelopmental, neurological, and psychiatric disorders....
Sun Mar 08, 2020 14:03
Related ArticlesHow the metabolic machinery of maximally exercising muscle fails. J Physiol. 2020 Mar 06;: Authors: Kemp GJ PMID: 32142588 [PubMed - as supplied by publisher]
Sat Mar 07, 2020 14:32
Related ArticlesFreezing translation at multiple levels one session at a time. J Physiol. 2020 Mar 05;: Authors: Figueiredo VC, von Walden F PMID: 32134509 [PubMed - as supplied by publisher]
Fri Mar 06, 2020 22:52
Related ArticlesProtease-dependent excitation of nodose ganglion neurons by commensal gut bacteria. J Physiol. 2020 Mar 05;: Authors: Pradhananga S, Tashtush AA, Allen-Vercoe E, Petrof EO, Lomax AE Abstract KEY POINTS: The vagus nerve has been implicated in mediating behavioral effects of the gut microbiota on the central nervous system. This study examined whether the secretory products of commensal gut bacteria can modulate the excitability of vagal...
Fri Mar 06, 2020 22:52
Related ArticlesStepping in circles: How locomotor signals of rotation adapt over time. J Physiol. 2020 Mar 05;: Authors: St George RJ, Day BL, Butler AA, Fitzpatrick RC Abstract KEY POINTS: While it has been well described that prolonged rotational stepping will adapt the podokinetic sense of rotation, the mechanisms involved are not clearly understood. By studying podokinetic after-rotations following conditioning rotations not previously reported...
Fri Mar 06, 2020 22:52
Related ArticlesCommon power laws for cities and spatial fractal structures. Proc Natl Acad Sci U S A. 2020 Mar 06;: Authors: Mori T, Smith TE, Hsu WT Abstract City-size distributions are known to be well approximated by power laws across a wide range of countries. But such distributions are also meaningful at other spatial scales, such as within certain regions of a country. Using data from China, France, Germany, India, Japan, and the United States,...
Sun Mar 08, 2020 13:43
Related ArticlesEarly intraneuronal amyloid triggers neuron-derived inflammatory signaling in APP transgenic rats and human brain. Proc Natl Acad Sci U S A. 2020 Mar 06;: Authors: Welikovitch LA, Do Carmo S, Maglóczky Z, Malcolm JC, Lőke J, Klein WL, Freund T, Cuello AC Abstract Chronic inflammation during Alzheimer's disease (AD) is most often attributed to sustained microglial activation in response to amyloid-β (Aβ) plaque deposits and cell death....
Sun Mar 08, 2020 13:43
Related ArticlesChromosome-free bacterial cells are safe and programmable platforms for synthetic biology. Proc Natl Acad Sci U S A. 2020 Mar 06;: Authors: Fan C, Davison PA, Habgood R, Zeng H, Decker CM, Gesell Salazar M, Lueangwattanapong K, Townley HE, Yang A, Thompson IP, Ye H, Cui Z, Schmidt F, Hunter CN, Huang WE Abstract A type of chromosome-free cell called SimCells (simple cells) has been generated from Escherichia coli, Pseudomonas putida,...
Sun Mar 08, 2020 13:43
Related ArticlesCentral neurogenetic signatures of the visuomotor integration system. Proc Natl Acad Sci U S A. 2020 Mar 06;: Authors: Bueichekú E, Aznárez-Sanado M, Diez I, d'Oleire Uquillas F, Ortiz-Terán L, Qureshi AY, Suñol M, Basaia S, Ortiz-Terán E, Pastor MA, Sepulcre J Abstract Visuomotor impairments characterize numerous neurological disorders and neurogenetic syndromes, such as autism spectrum disorder (ASD) and Dravet, Fragile X, Prader-Willi,...
Sun Mar 08, 2020 13:43
21 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: "Proc Natl Acad Sci U S A"[jour] These pubmed results were generated on 2020/03/07PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Sat Mar 07, 2020 16:16
21 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: "Proc Natl Acad Sci U S A"[jour] These pubmed results were generated on 2020/03/07PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Sat Mar 07, 2020 14:18
Related ArticlesAnterior cingulate cortex is necessary for adaptation of action plans. Proc Natl Acad Sci U S A. 2020 Mar 04;: Authors: Brockett AT, Tennyson SS, deBettencourt CA, Gaye F, Roesch MR Abstract Previous research has focused on the anterior cingulate cortex (ACC) as a key brain region in the mitigation of the competition that arises from two simultaneously active signals. However, to date, no study has demonstrated that ACC is necessary...
Fri Mar 06, 2020 22:42
Related ArticlesExtreme mechanical resilience of self-assembled nanolabyrinthine materials. Proc Natl Acad Sci U S A. 2020 Mar 04;: Authors: Portela CM, Vidyasagar A, Krödel S, Weissenbach T, Yee DW, Greer JR, Kochmann DM Abstract Low-density materials with tailorable properties have attracted attention for decades, yet stiff materials that can resiliently tolerate extreme forces and deformation while being manufactured at large scales have remained...
Fri Mar 06, 2020 22:42
Related ArticlesActive volume regulation in adhered cells. Proc Natl Acad Sci U S A. 2020 Mar 04;: Authors: Adar RM, Safran SA Abstract Recent experiments reveal that the volume of adhered cells is reduced as their basal area is increased. During spreading, the cell volume decreases by several thousand cubic micrometers, corresponding to large pressure changes of the order of megapascals. We show theoretically that the volume regulation of adhered cells...
Fri Mar 06, 2020 22:42
Related ArticlesTranscriptional repression specifies the central cell for double fertilization. Proc Natl Acad Sci U S A. 2020 Mar 04;: Authors: Zhang MX, Zhu SS, Xu YC, Guo YL, Yang WC, Li HJ Abstract Double fertilization is a key innovation for the evolutionary success of angiosperms by which the two fertilized female gametes, the egg cell and central cell, generate the embryo and endosperm, respectively. The female gametophyte (embryo sac) enclosed...
Fri Mar 06, 2020 22:42
Related ArticlesCommunication cost of consensus for nodes with limited memory. Proc Natl Acad Sci U S A. 2020 Mar 04;: Authors: Fanti G, Holden N, Peres Y, Ranade G Abstract Motivated by applications in wireless networks and the Internet of Things, we consider a model of n nodes trying to reach consensus with high probability on their majority bit. Each node i is assigned a bit at time 0 and is a finite automaton with m bits of memory (i.e., [Formula:...
Fri Mar 06, 2020 22:42
Related ArticlesMetabolic and genetic basis for auxotrophies in Gram-negative species. Proc Natl Acad Sci U S A. 2020 Mar 04;: Authors: Seif Y, Choudhary KS, Hefner Y, Anand A, Yang L, Palsson BO Abstract Auxotrophies constrain the interactions of bacteria with their environment, but are often difficult to identify. Here, we develop an algorithm (AuxoFind) using genome-scale metabolic reconstruction to predict auxotrophies and apply it to a series of...
Fri Mar 06, 2020 22:42
Related ArticlesHierarchically porous Au nanostructures with interconnected channels for efficient mass transport in electrocatalytic CO2 reduction. Proc Natl Acad Sci U S A. 2020 Mar 04;: Authors: Hyun G, Song JT, Ahn C, Ham Y, Cho D, Oh J, Jeon S Abstract Electrocatalytic CO2 reduction is a promising way to provide renewable energy from gaseous CO2 The development of nanostructures improves energy efficiency and selectivity for value-added chemicals,...
Fri Mar 06, 2020 22:42
Related ArticlesAssessing thyroid cancer risk using polygenic risk scores. Proc Natl Acad Sci U S A. 2020 Mar 04;: Authors: Liyanarachchi S, Gudmundsson J, Ferkingstad E, He H, Jonasson JG, Tragante V, Asselbergs FW, Xu L, Kiemeney LA, Netea-Maier RT, Mayordomo JI, Plantinga TS, Hjartarson H, Hrafnkelsson J, Sturgis EM, Brock P, Nabhan F, Thorleifsson G, Ringel MD, Stefansson K, de la Chapelle A Abstract Genome-wide association studies (GWASs) have identified...
Fri Mar 06, 2020 22:42
Related ArticlesProgramming colloidal bonding using DNA strand-displacement circuitry. Proc Natl Acad Sci U S A. 2020 Mar 04;: Authors: Zhou X, Yao D, Hua W, Huang N, Chen X, Li L, He M, Zhang Y, Guo Y, Xiao S, Bian F, Liang H Abstract As a strategy for regulating entropy, thermal annealing is a commonly adopted approach for controlling dynamic pathways in colloid assembly. By coupling DNA strand-displacement circuits with DNA-functionalized colloid...
Fri Mar 06, 2020 22:42
Related ArticlesTDP-43 α-helical structure tunes liquid-liquid phase separation and function. Proc Natl Acad Sci U S A. 2020 Mar 04;: Authors: Conicella AE, Dignon GL, Zerze GH, Schmidt HB, D'Ordine AM, Kim YC, Rohatgi R, Ayala YM, Mittal J, Fawzi NL Abstract Liquid-liquid phase separation (LLPS) is involved in the formation of membraneless organelles (MLOs) associated with RNA processing. The RNA-binding protein TDP-43 is present in several MLOs, undergoes...
Fri Mar 06, 2020 22:42
Related ArticlesCircadian control of interferon-sensitive gene expression in murine skin. Proc Natl Acad Sci U S A. 2020 Mar 04;: Authors: Greenberg EN, Marshall ME, Jin S, Venkatesh S, Dragan M, Tsoi LC, Gudjonsson JE, Nie Q, Takahashi JS, Andersen B Abstract The circadian clock coordinates a variety of immune responses with signals from the external environment to promote survival. We investigated the potential reciprocal relationship between the...
Fri Mar 06, 2020 22:42
Related ArticlesVisualizing the translation and packaging of HIV-1 full-length RNA. Proc Natl Acad Sci U S A. 2020 Mar 04;: Authors: Chen J, Liu Y, Wu B, Nikolaitchik OA, Mohan PR, Chen J, Pathak VK, Hu WS Abstract HIV-1 full-length RNA (HIV-1 RNA) plays a central role in viral replication, serving as a template for Gag/Gag-Pol translation and as a genome for the progeny virion. To gain a better understanding of the regulatory mechanisms of HIV-1 replication,...
Fri Mar 06, 2020 22:42
Related ArticlesLocalization of sterols and oxysterols in mouse brain reveals distinct spatial cholesterol metabolism. Proc Natl Acad Sci U S A. 2020 Mar 04;: Authors: Yutuc E, Angelini R, Baumert M, Mast N, Pikuleva I, Newton J, Clench MR, Skibinski DOF, Howell OW, Wang Y, Griffiths WJ Abstract Dysregulated cholesterol metabolism is implicated in a number of neurological disorders. Many sterols, including cholesterol and its precursors and metabolites,...
Fri Mar 06, 2020 22:42
Loss-of-function BK channel mutation causes impaired mitochondria and progressive cerebellar ataxia.
Related ArticlesLoss-of-function BK channel mutation causes impaired mitochondria and progressive cerebellar ataxia. Proc Natl Acad Sci U S A. 2020 Mar 04;: Authors: Du X, Carvalho-de-Souza JL, Wei C, Carrasquel-Ursulaez W, Lorenzo Y, Gonzalez N, Kubota T, Staisch J, Hain T, Petrossian N, Xu M, Latorre R, Bezanilla F, Gomez CM Abstract Despite a growing number of ion channel genes implicated in hereditary ataxia, it remains unclear how ion channel mutations...
Fri Mar 06, 2020 22:42
Η παχυσαρκία αποτελεί έναν από τους κορυφαίους παράγοντες που συμβάλλουν στην ανάπτυξη καρκίνου παγκοσμίως. Επιδημιολογικές μελέτες που έχουν ασχοληθεί με τις εκφάνσεις της παχυσαρκίας σε πληθυσμιακά δείγματα, έχουν αποδείξει πως η διατροφή επηρεάζει τις πιθανότητες εμφάνισης καρκίνου. Ωστόσο, οι διατροφικές συνήθειες δεν αυξάνουν απλώς τις πιθανότητες εμφάνισης καρκίνου, αλλά επηρεάζουν και τον βαθμό ανταπόκρισης στην αντικαρκινική θεραπεία, και σίγουρα όχι θετικά. Τα παραπάνω διαπιστώνει νέα...
Fri Mar 06, 2020 18:36
Οι ηλικιωμένοι που συνηθίζουν να κοιμούνται κατά τη διάρκεια της ημέρας είναι πιο πιθανό να διαγνωσθούν με καρδιακές παθήσεις ή καρκίνο, υποστηρίζουν οι επιστήμονες σε μια νέα μελέτη τους, η οποία παρουσιάστηκε στο συνέδριο της Αμερικανικής Ακαδημίας Νευρολογίας στο Τορόντο. Στη μελέτη, που συμμετείχαν 10.930 άνθρωποι, αναδείχθηκε ότι όσοι από αυτούς ένιωθαν υπνηλία κατά τη διάρκεια της ημέρας διέτρεχαν 2,5 φορές μεγαλύτερο κίνδυνο καρδιακών παθήσεων. Ο αντίστοιχος κίνδυνος για τον καρκίνο ήταν...
Fri Mar 06, 2020 17:52
Μια ποσότητα 2,5 ποτηριών χυμού πορτοκαλιού ημερησίως μπορεί να αναστρέψει την παχυσαρκία και να μειώσει τον κίνδυνο καρδιακών παθήσεων και διαβήτη, σύμφωνα με έρευνα που δημοσιεύθηκε στο Journal of Lipid Research. Το όφελος αυτό αποδίδεται από τους ερευνητές του Πανεπιστημίου του Δυτικού Οντάριο στη νοβιλετίνη, ένα μόριο που βρίσκεται στα γλυκά πορτοκάλια και τα μανταρίνια. Πιο αναλυτικά, η μελέτη έδειξε ότι τα ποντίκια που ακολουθούσαν διατροφή με υψηλή περιεκτικότητα σε λιπαρά και χοληστερόλη,...
Fri Mar 06, 2020 16:52
Νέα έρευνα από το Πανεπιστήμιο Queen Mary του Λονδίνου, ανακάλυψε τη θετική επίδραση ενός φαρμάκου που χρησιμοποιείται ευρέως για τη θεραπεία του διαβήτη τύπου 2 σε ασθενείς που ακολουθούν θεραπεία με κορτικοστεροειδή. Κατά τη δεύτερη φάση της κλινικής δοκιμής, οι ερευνητές εξέτασαν την επίδραση της μετφορμίνης, της ουσίας που χορηγείται για την αντιμετώπιση του διαβήτη, σε ασθενείς που λάμβαναν υψηλές δόσεις γλυκοκορτικοειδών, έναν τύπο κορτικοστεροειδών που χρησιμοποιούνται για τη θεραπεία χρόνιων...
Fri Mar 06, 2020 14:18
Μια διεθνής ομάδα επιστημόνων βρήκε ότι όταν ένας άνθρωπος δεν αντιμετωπίζεται με σεβασμό από τους άλλους μπορεί να οδηγηθεί σε κυνικές πεποιθήσεις για όσον αφορά στην ανθρώπινη φύση, οι οποίες με τη σειρά τους συμβάλλουν στην επανάληψη της ασεβούς συμπεριφοράς τόσο από την πλευρά των άλλων όσο και από την πλευρά του ίδιου του ατόμου. Σύμφωνα με τη σχετική δημοσίευση στο Experimental Psychology: General, οι διατομεακές, μακροχρόνιες και πειραματικές μελέτες των επιστημόνων έδειξαν ότι η έλλειψη...
Fri Mar 06, 2020 13:18
Το αν ένα παιδί θα αναπτύξει αλλεργίες επηρεάζεται σε μικρό βαθμό από το αν έχει γεννηθεί με καισαρική τομή ή φυσιολογικά, υποστηρίζει νέα μελέτη που διενεργήθηκε από το Παιδικό Ερευνητικό Ινστιτούτο Murdoch (MCRI) και δημοσιεύθηκε στο Archives of Disease in Childhood. Πιο αναλυτικά, στη μελέτη αναδείχθηκε μόνο μια μικρή σύνδεση ανάμεσα στον τοκετό με καισαρική τομή και το άσθμα και καμία σύνδεση ανάμεσα στη μέθοδο τοκετού και το έκζεμα ή την πνευμονική λειτουργία. Η ερευνητική ομάδα υπό την επίβλεψη...
Fri Mar 06, 2020 12:47
Το κάπνισμα του ιδιαιτέρως δημοφιλούς σε ενήλικες και εφήβους ναργιλέ, έχει θεωρηθεί μια λιγότερο επιβλαβής συνήθεια από τα συμβατικά τσιγάρα. Νέα έρευνα ωστόσο, η οποία δημοσιεύτηκε στο Arteriosclerosis, Thrombosis and Vascular Biology (ATVB), παρουσιάζει ένα ιδιαίτερα τοξικό προφίλ της συσκευής καπνίσματος, πιο επιβλαβές και από αυτό των συμβατικών τσιγάρων. Πειράματα σε ποντίκια, έδειξαν για πρώτη φορά ότι ο καπνός από ναργιλέ προκαλεί ανωμαλίες στη λειτουργία του αίματος, αυξάνοντας τις πιθανότητες...
Fri Mar 06, 2020 11:25
Τα μικρά παιδιά από οικογένειες με χαμηλό εισόδημα των οποίων οι μητέρες αναφέρουν τακτική χρήση οικιακών καθαριστικών που περιέχουν τοξικές ουσίες είναι πιθανότερο να έχουν γλωσσική αναπτυξιακή υστέρηση σε ηλικία 24 μηνών, σύμφωνα με νέα αμερικανική μελέτη. Όπως προκύπτει από άρθρο που δημοσιεύθηκε στο Clinical Pediatrics, επιστημονική ομάδα του Πολιτειακού Πανεπιστημίου του Οχάιο ανέλυσε στοιχεία που αφορούσαν σε 190 οικογένειες από τη μελέτη Kids, που είχε θέσει υπό ιατρική παρακολούθηση παιδιά...
Fri Mar 06, 2020 09:21
Σε αντίθεση με τις συστάσεις των επαγγελματιών υγείας που συμβουλεύουν τους γονείς να επιλέγουν ημίπαχο γάλα για τα παιδιά τους, μια νέα μελέτη Αυστραλών ερευνητών που δημοσιεύθηκε στο Advances in Nutrition, δείχνει ότι το ολόπαχο γάλα δεν αυξάνει τον κίνδυνο παχυσαρκίας για τα παιδιά. Επανεξετάζοντας 29 μελέτες από όλο τον κόσμο, οι επιστήμονες δεν βρήκαν καμία σαφή σύνδεση ανάμεσα στα δύο, υποστηρίζοντας μάλιστα ότι οτιδήποτε άλλο από το ολόπαχο γάλα μπορεί να κάνει τα παιδιά να νιώθουν ότι πεινούν...
Fri Mar 06, 2020 08:54
Η υψηλή αρτηριακή πίεση επηρεάζει συνολικά τον οργανισμό, από τη λειτουργία των αρτηριών μέχρι τους νεφρούς, και από την όραση μέχρι τις σεξουαλικές επιδόσεις. Ωστόσο, στη μέση ηλικία η υπέρταση φαίνεται να συνδέεται και με παθήσεις σχετικές με τη γνωστική εξασθένιση, ως αποτέλεσμα της διακοπτόμενης ροής του αίματος προς τον εγκέφαλο, αλλά και με τα εγκεφαλικά επεισόδια, τα εμφράγματα και τη μειωμένη κινητική ικανότητα. Μια νέα μελέτη, λοιπόν, από ερευνητές των Πανεπιστημίων Northwestern και του...
Fri Mar 06, 2020 08:11
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