Purpose: To describe patients presenting with sudden onset of localized hemorrhage from a presumed acute spontaneous rupture of the superior ophthalmic vein. Methods: A retrospective review of the pattern of presentation, clinical implications and outcomes, and the characteristic imaging and histologic features. Results: Six patients (5 men; 84%) presented at a mean age of 45 years (range 15–72), with the commonest symptoms and signs being acute onset of Valsalva-negative proptosis...
Mon Mar 02, 2020 02:00
Orbital actinomyces is a rare diagnosis with only a few cases reported in the literature. It can be difficult to diagnose due to its slow, indolent course, and nonspecific findings on imaging and clinical examination, and frequently it can masquerade as other pathologies such as neoplasm and inflammatory disease. The authors present a case of actinomyces masquerading as meningioma with findings of hyperostosis and a superior orbital roof interosseous tract on imaging. Accepted for publication...
Mon Mar 02, 2020 02:00
Purpose: To test whether intraoperative stereotactic navigation during orbital decompression surgery resulted in quantifiable surgical benefit. Methods: This retrospective cohort study examined all consecutive patients who underwent primary orbital decompression surgery for thyroid associated orbitopathy performed by a single surgeon (A.K.) during the periods of 2012–2014 (non-navigated), and 2017–2018 (navigated). The study was HIPAA-compliant, was approved by the Institutional Review...
Mon Mar 02, 2020 02:00
Purpose: To determine the association of Fitzpatrick skin type (FST) with conjunctival melanoma. Methods: Retrospective case series of 540 patients with conjunctival melanoma to assess clinical features and outcomes per FST. Results: The FST was Type I (n = 126, 23%), II (n = 337, 62%), III (n = 56, 10%), IV (n = 8, 2%), V (n = 12, 2%), and VI (n = 1,
Mon Mar 02, 2020 02:00
Purpose: To perform a comprehensive review of dermis fat graft (DFG) in socket reconstruction and illustrate the technical nuances and outcomes using a retrospective case review. Methods: A literature search of 143 texts was reviewed. A retrospective case series of 34 patients following primary or secondary DFG after enucleation at a single institution (2009–2019) was performed. Clinical outcomes were statistically analyzed. Variables investigated included age, sex, race, surgical indication,...
Mon Mar 02, 2020 02:00
Abstract Oral cancer is one of the highly prevalent cancers in many parts of the world. The last release of the GLOBOCAN database (http://globocan.iarc.fr/) reported over 350,000 new cases and over 170,000 deaths among both males and females of all ages in 2018. Notably, more than half of the cases are contributed by Asia (64.2%), with 227,906 new cases and 129,929 number of deaths recorded in 2018.
Sun Mar 08, 2020 03:06
Abstract Objectives To assess the global oral lichen planus prevalence. Material and methods We searched PubMed, Embase, Web of Science, and Scopus for studies published before Sep‐2019. We evaluated the quality of studies and carried out several meta‐analyses. Results The global pooled prevalence was 1.01%, with a marked geographical difference (p<0.001).The highest prevalence was reported from Europe (1.43%) and the lowest in India (0.49%), where tobacco‐associated...
Sat Mar 07, 2020 13:18
Abstract Objectives We aimed to investigate whether skeletal‐specific H‐type blood vessels exist in alveolar bone and how they function in alveolar bone remodeling. Materials and Methods H‐type vessels with high expression of CD31 and Endomucin (CD31hiEmcnhi) were immunostained in alveolar bone. Abundance and age‐related changes of CD31hiEmcnhi endothelial cells (H‐ECs) were detected by flow cytometry. Osteoprogenitors association with H‐type vessels, and bone mass were detected...
Sat Mar 07, 2020 13:18
Abstract Objectives We aimed to provide pooled estimates of human papillomavirus (HPV) prevalence in oral potentially malignant disorders (OPMD) and evaluate the impact of presence of epithelial dysplasia. Methods We searched Pubmed, Embase and Cochrane Library databases for studies that examined the prevalence of HPV DNA in OPMD tested by polymerase chain reaction (PCR). Results Across 52 eligible studies (2677 cases) we found an overall pooled HPV prevalence of 22.5%...
Sat Mar 07, 2020 09:14
Office-based injection laryngoplasty (IL) has emerged as a useful procedure for otolaryngologists to correct glottic insufficiency while avoiding the costs and risks of general anesthesia. This is the first study focused on addressing the safety of bilateral IL for bilateral vocal fold (VF) atrophy.
Sat Mar 07, 2020 02:00
In the cat four different types of vocalization, mews, howls, cries, and hisses were generated by microstimulation in different parts of the periaqueductal gray (PAG). While mews imply positive vocal expressions, howls, hisses, and cries represent negative vocal expressions. In the intermediate PAG, mews were generated in the lateral column, howls, and hisses in the ventrolateral column. Cries were generated in two other regions, the lateral column of the rostral PAG and the ventrolateral column...
Fri Mar 06, 2020 02:00
Post-transplant lymphoproliferative disease (PTLD) is a clinicopathologic entity characterized by an abnormal lymphocytic proliferation that occurs in immunosuppressed patients following organ transplantation. Several sites in the head and neck may be affected by PTLD with rare involvement of the larynx. Affected patients often present with symptoms and signs suggestive of a malignant lesion. Early diagnosis using histopathologic examination is paramount to prevent life-threatening airway compromise.
Fri Mar 06, 2020 02:00
The aim of this retrospective study was to use computer-aided design and manufacturing (CAD/CAM) patient-specific plates and cutting guides for the waferless positioning and fixation of the maxilla after bimaxillary osteotomies in cases of hemifacial microsomia with condylar dysplasia or absence of the temporomandibular joint (TMJ), and to compare the results with the CAD/CAM fabricated surgical wafer by 3-dimensional analysis. Eighteen patients were selected from the hospital database, preoperative...
Sat Mar 07, 2020 02:00
New way to reduce the length and bulk of a two-perforator anterolateral thigh flap: a technical note
The anterolateral thigh (ALT) flap is a reliable technique for the reconstruction of many head and neck defects. It is based on one or more cutaneous perforators that arise from the descending branch of the circumflex femoral vessels. Perforator anatomy in this region is variable, but adequate vessels are found in most cases, usually aided by preoperative Doppler localisation. In a recent systematic review, including 1251 thighs, researchers found that the mean number of perforators in ALT flaps...
Fri Mar 06, 2020 02:00
Abstract Objective This meta‐analysis was performed to systematically evaluate the efficacy of hyaluronidase combined with corticosteroids compared with other drugs in improving maximum mouth opening and alleviating the burning sensation in patients with oral submucous fibrosis (OSF). Methods PubMed, Embase, Web of Science, and the Cochrane Library were searched. RevMan 5.3 software was used for the meta‐analysis. Results Six studies involving 244 patients with OSF were...
Sat Mar 07, 2020 23:26
Background. As a pathological process, osteonecrosis of the femoral head (ONFH) is characterized by the avascularity of the femoral head, cellular necrosis, microfracture, and the collapse of the articular surface. Currently, critical treatment for early-stage ONFH is limited to core decompression. However, the efficacy of core decompression remains controversial. To improve the core decompression efficacy, regenerative techniques such as the use of platelet-rich plasma (PRP) were proposed for early-stage...
Sat Mar 07, 2020 16:50
Aim. Sarcopenia, a core component of physical frailty, is an independent risk factor for suboptimal health outcomes in hospitalized patients, especially in the intensive care patients. Psoas muscle areas can be assessed to identify sarcopenia. The aim of this study was to determine the prognostic value of psoas muscle area measured with CT for the prediction of in-hospital mortality in patients with pulmonary embolism at admission to the intensive care unit. Methods. Patients with an admission abdominal...
Sat Mar 07, 2020 16:50
Background. Tripartite motif containing 58 (TRIM58), an E3 ubiquitin ligase, is reported as a suppressor gene in certain human tumors. However, the biological function of TRIM58 in osteosarcoma (OS) is still less identified. Methods. In the present study, TRIM58 induced silencing and overexpression in OS cells using RNA interference (RNAi) and lentiviral-mediated vector, respectively. Cell proliferation profiles were analyzed using cell counting kit-8 (CCK-8) assay. Cell apoptosis profiles were determined...
Sat Mar 07, 2020 16:20
Objective. The aim of this study is to evaluate the association of genetic polymorphisms in Cytochrome P450 2D6(CYP2D6) and the change in VEGF levels with the response to propranolol in patients with Infantile hemangiomas (IH). Methods. IH patients who underwent over six months of propranolol therapy and received oral propranolol only were enrolled. The target dose of propranolol was 1 mg kg−1day−1. Deoxyribonucleic acid was obtained from venous blood leukocytes. Genotypes of CYP2D6 (rs1065852 and...
Sat Mar 07, 2020 16:05
Maitake (Grifola frondosa) mushroom has received an enormous amount of attention as a dietary supplement due to its high nutritional values. The particle sizes of G. frondosa mushrooms were monitored by a classifying mill. β-Glucans are the bioactive component of the mushroom, and it was revealed through Fourier transform infrared spectroscopy (FTIR), proton and carbon nuclear magnetic resonance (1H and 13C-NMR), matrix-assisted laser desorption/ionization, and time-of-flight (MALDI-TOF) spectrometry....
Sat Mar 07, 2020 16:05
Background. Autoantibodies against apolipoprotein A-1 (anti-ApoA-1 IgG) were demonstrated to be associated with cardiovascular outcomes in several inflammatory diseases. As balanced inflammation is critical for uncomplicated pregnancy, we aimed to investigate the prevalence of anti-ApoA-1 IgG and anti-c-terminal ApoA-1 autoantibodies (Ac-terAA1 IgG) in a cohort of pregnant women and their potential relationship with threatened abortion (TA). Methods. Between 2012 and 2014, 371 consecutive outpatient...
Sat Mar 07, 2020 15:05
Cutaneous squamous cell carcinoma (cSCC) is one of the most common skin cancers. In the treatment of cSCC, it is necessary to remove it completely, and reconstructive surgery, such as a skin graft or a local or free flap, will be required, depending on the size, with donor-site morbidity posing a burden to the patient. The high hydrostatic pressure (HHP) technique has been developed as a physical method of decellularizing various tissues. We previously reported that HHP at 200 MPa for 10 min could...
Sat Mar 07, 2020 13:50
Background. The purpose of this study was to evaluate the association between the non-high-density lipoprotein cholesterol (non-HDL-C) to high-density lipoprotein cholesterol (HDL-C) ratio and the risk of coronary artery disease (CAD). We also explored the potential role of non-HDL-C/HDL-C in the prognosis of CAD. Methods. We analyzed 930 consecutive patients with chest discomfort who underwent coronary angiography. Of these, 680 were diagnosed with CAD; the remaining 250 patients were normal. Multivariate...
Sat Mar 07, 2020 13:20
This study is to investigate the effect of Paeonia lactiflora extract on PMS anxiety and on expression of estrogen receptor β (ERβ), tryptophan hydroxylase-2 (TPH2), and serotonin transporter (SERT) in the premenstrual syndrome (PMS) anxiety model rats. The vaginal smear and open field test were used to screen rats in nonreception phase of estrus cycle with similar macroscopic behaviors and regular estrus cycle. PMS anxiety model rats were prepared by electrical stimulation. RT-PCR and immunofluorescence...
Sat Mar 07, 2020 12:50
Objective. The aim of this study was to investigate the prognostic significance of the preoperative neutrophil-to-lymphocyte ratio (NLR) in small renal cell carcinoma (sRCC, ≤4 cm). Methods. This study was approved by the review board (NO.XYFY2019-KL032-01). Between 2007 and 2016, a total of 384 consecutive patients who underwent curative surgery for sRCC at our institution were evaluated. Patients were divided into high NLR and low NLR groups by plotting the NLR receiver operating characteristic...
Fri Mar 06, 2020 17:50
Objective. Our aim was to assess the efficacy and safety of acupuncture for OSA patients with various severities of the disorder. Methods. Eight databases including PubMed, Cochrane Library, EMBASE, Web of Science, China National Knowledge Infrastructure (CNKI), Chongqing VIP (CQVIP), Wanfang Data, and Chinese Biomedical Literature Database (CBM) were comprehensively searched till July 2019. Randomized controlled trials (RCTs) testing acupuncture in the treatment of OSA were eligible for inclusion....
Fri Mar 06, 2020 17:50
Several studies have reported the association between polycystic ovary syndrome (PCOS) and low-grade chronic inflammation to be of uncertain cause: obesity, insulin resistance, or PCOS itself. The aim of the study was to investigate the WBC (white blood cell) count and CRP (C-reactive protein) concentration in women with PCOS and to determine the factors that affect their concentration. The study included 200 women aged 18-40 with PCOS and 105 healthy women as the control group, recruited in the...
Fri Mar 06, 2020 17:50
The MnSOD Ala16Val single nucleotide polymorphism (SNP) has been associated with different diseases. However, there are scarcely studies relating this SNP in epilepsy, a neurologic disease that involves some interacting pathways, such as apoptotic and inflammatory factors. In this sense, we decided to investigate the relationship of MnSOD Ala16Val SNP with apoptotic markers in epilepsy and its relation with inflammatory pathway and seizure type. Ninety subjects were evaluated (47 epilepsies; 43 controls)...
Fri Mar 06, 2020 17:50
Tai Chi is an available method for the treatment of knee osteoarthritis (KOA). The impacts of Tai Chi on plantar loads of individuals with KOA are not fully understood. 46 participants with knee osteoarthritis were randomly assigned into the Tai Chi group () or the control group (). The Tai Chi group attended a 6-month Tai Chi program, and the control group participated in a wellness education program. Novel Pedar-X system was used to collect the peak pressure (PP) and maximum force (MF) during walking...
Fri Mar 06, 2020 17:50
Summary Background Metformin use is associated with reduced cancer risk in epidemiological studies and has preclinical anti-cancer activity in ovarian cancer models. The primary objective of this phase I study was to determine the recommended phase II dose (RP2D) of metformin in combination with carboplatin/paclitaxel in patients with ovarian cancer. Secondary objectives were to describe safety and pharmacokinetics. Methods In this single-center trial the RP2D of metformin in...
Sat Mar 07, 2020 02:00
Abstract ENT involvement is common in ANCA‐associated vasculitis (AAV), particularly in GPA and EGPA. Early recognition and treatment is important for good outcomes, yet evidence suggests that UK ENT surgeons may not consistently recognise the early features of AAV, despite a similar incidence to vestibular schwannoma. AAV is a rapidly advancing field, with significant developments in the understanding of its pathogenesis, classification and treatment over the past decade. Relevant vasculitis mimics...
Sat Mar 07, 2020 21:26
Abstract Objectives It is well established that sequential bilateral implantation offers functional benefits in speech in noise and sound localisation, although it can be challenging to get long‐term unilateral users to adapt to the second implant. The aim of this study was to investigate programming differences between the two cochlear implants that can impact on performance outcomes. Design Cohort Study Participants Sixteen older children who received sequential implants in Ireland...
Sat Mar 07, 2020 09:18
Abstract Success rate in tympanoplasty can deteriorate with time after initial graft healing. Early successful repair of tympanic membrane does not necessarily guarantee permanent closure. It might be prudent to have long‐term follow up after tympanoplasty in a select group of patients. Potential risks factors for delayed failure include a continued smoking history, bilateral perforations and tympanosclerosis at time of surgery or its development post‐operatively. The success...
Sat Mar 07, 2020 03:15
Abstract Objective To investigate the influence of family environment on the development of speech and language in preschool children after cochlear implantation. Methods A total of 88 prelingually deaf children, aged from 2 to 5 years, who received cochlear implantation were included in this study. All families completed a self‐report family environment questionnaire (FES). The deaf children's linguistic progress was assessed by Categories of Auditory Performance (CAP) and Speech Intelligibility...
Sat Mar 07, 2020 03:15
Current evidence for the effectiveness of post-stroke cognitive rehabilitation is weak, possibly due to two reasons. First, patients typically express cognitive deficits in several domains. Therapies focusing ...
Fri Mar 06, 2020 02:00
There is scientific evidence that older adults aged 65 and over walk with increased step width variability which has been associated with risk of falling. However, there are presently no threshold levels that ...
Thu Mar 05, 2020 02:00
Publication date: June 2020Source: Biomedicine & Pharmacotherapy, Volume 126Author(s): Huiqing Lv, Zihan Li, Zhijun Xie, Xuanming Hu, Haichang Li, Jing Sun, Xuezhi Chen, Chengping Wen
Sat Mar 07, 2020 19:54
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου