Related ArticlesThe post-treatment neutrophil-to-lymphocyte ratio and changes in this ratio predict survival after treatment of stage III non-small-cell lung cancer with conventionally fractionated radiotherapy. Future Oncol. 2020 Mar 06;: Authors: Wang D, Guo D, Li A, Wang P, Teng F, Yu J Abstract Aim: To investigate the predictive potential of post-treatment neutrophil-to-lymphocyte ratio (NLR) and changes in this ratio (ΔNLR) for stage III non-small-cell...
Sat Mar 07, 2020 14:27
Related ArticlesA nomogram for predicting overall survival in patients with uterine leiomyosarcoma: a SEER population-based study. Future Oncol. 2020 Mar 06;: Authors: Lu YJ, Wang H, Fang LY, Wang WJ, Song W, Wang Y, Huang YQ, Din ZL Abstract Aim: To establish and validate a nomogram for the estimation of overall survival of patients with uterine leiomyosarcoma (uLMS). Methods: Information on patients diagnosed as uLMS was retrospectively retrieved from...
Sat Mar 07, 2020 14:27
Related ArticlesDevelopment of an Isocentric Rotating Chair Positioner to Treat Patients of Head and Neck Cancer at Upright Seated Position with Multiple Nonplanar Fields in a Fixed Carbon-Ion Beamline. Med Phys. 2020 Mar 05;: Authors: Zhang X, Hsi WC, Yang F, Wang Z, Sheng Y, Sun J, Yang C, Zhou R Abstract PURPOSE: An isocentric rotating chair for a positioner was developed as a non-gantry solution to provide multiple nonplanar radiation fields with...
Sat Mar 07, 2020 13:28
Related ArticlesNon-nutritional "paramedical" usage of human milk - knowledge and opinion of breastfeeding mothers in Poland. Ginekol Pol. 2020;91(2):79-84 Authors: Karcz K, Makuch J, Walkowiak M, Olejnik I, Krolak-Olejnik B Abstract OBJECTIVES: The objective of this study is to understand knowledge, attitudes and practices of non-nutritional breast milk use among lactating women in respect of skin diseases and other frequent ailments. MATERIAL...
Sat Mar 07, 2020 13:28
Motivations, Well-Being, and Career Aspirations of Radiation Oncology Resident Physicians in Canada.
Related ArticlesMotivations, Well-Being, and Career Aspirations of Radiation Oncology Resident Physicians in Canada. J Cancer Educ. 2020 Mar 06;: Authors: Wang MH, Loewen SK, Giuliani M, Fairchild A, Yee D, Debenham BJ Abstract Prior Pan-Canadian surveys of Radiation Oncology (RO) residents reveal a decrease in Canadian RO employment opportunities. Canadian RO resident levels increased from 130 in 2003, peaked at 209 in 2009, then decreased to 130 in...
Sat Mar 07, 2020 13:28
Related ArticlesRadiographic characteristics of neuroendocrine liver metastases do not predict clinical outcomes following liver resection. Hepatobiliary Surg Nutr. 2020 Feb;9(1):1-12 Authors: Armstrong EA, Beal EW, Shah M, Konda B, Abdel-Misih S, Ejaz A, Dillhoff ME, Pawlik TM, Cloyd JM Abstract Background: Previous research has demonstrated that specific radiographic criteria, including the presence of calcifications and the enhancement pattern on...
Sat Mar 07, 2020 13:28
Related ArticlesLatent Risk Intrahepatic Cholangiocarcinoma Susceptible to Adjuvant Treatment After Resection: A Clinical Deep Learning Approach. Front Oncol. 2020;10:143 Authors: Jeong S, Ge Y, Chen J, Gao Q, Luo G, Zheng B, Sha M, Shen F, Cheng Q, Sui C, Liu J, Wang H, Xia Q, Chen L Abstract Background: Artificial Intelligence (AI) frameworks have emerged as a novel approach in medicine. However, information regarding its applicability and effectiveness...
Sat Mar 07, 2020 13:28
Related ArticlesStem cells out of the bag: characterization of ex vivo expanded mesenchymal stromal cells for possible clinical use. Future Sci OA. 2020 Jan 06;6(3):FSO449 Authors: Lopes SM, Roncon S, Bordalo F, Amado F, Ferreira S, Pinho AC, Vieira J, Costa-Pereira A Abstract Aim: Mesenchymal stromal cells (MSC) are a promising tool for cellular therapy and regenerative medicine. One major difficulty in establishing a MSC expansion protocol is the large...
Sat Mar 07, 2020 13:28
Related ArticlesLow-Dose radiation therapy for benign pathologies. Rep Pract Oncol Radiother. 2020 Mar-Apr;25(2):250-254 Authors: Torres Royo L, Antelo Redondo G, Árquez Pianetta M, Arenas Prat M Abstract Radiotherapy (RT) has always been a mainstay for malignant tumors therapy, but it is also used for benign pathology. The application of low or intermediate doses of RT has been widely studied. This topic was presented and discussed in the last XX GOCO...
Sat Mar 07, 2020 13:28
Related ArticlesUpdate Breast Cancer 2020 Part 1 - Early Breast Cancer: Consolidation of Knowledge About Known Therapies. Geburtshilfe Frauenheilkd. 2020 Mar;80(3):277-287 Authors: Schneeweiss A, Hartkopf AD, Müller V, Wöckel A, Lux MP, Janni W, Ettl J, Belleville E, Huober J, Thill M, Fasching PA, Kolberg HC, Pöschke P, Welslau M, Overkamp F, Tesch H, Fehm TN, Lüftner D, Schütz F Abstract This review is intended to present the latest developments in...
Sat Mar 07, 2020 13:28
Related ArticlesBig data in digital healthcare: lessons learnt and recommendations for general practice. Heredity (Edinb). 2020 Mar 05;: Authors: Agrawal R, Prabakaran S Abstract Big Data will be an integral part of the next generation of technological developments-allowing us to gain new insights from the vast quantities of data being produced by modern life. There is significant potential for the application of Big Data to healthcare, but there are...
Sat Mar 07, 2020 13:28
Related ArticlesExercise and the Kynurenine pathway: Current state of knowledge and results from a randomized cross-over study comparing acute effects of endurance and resistance training. Exerc Immunol Rev. 2020;26:24-42 Authors: Joisten N, Kummerhoff F, Koliamitra C, Schenk A, Walzik D, Hardt L, Knoop A, Thevis M, Kiesl D, Metcalfe AJ, Bloch W, Zimmer P Abstract INTRODUCTION: The essential amino acid tryptophan (TRP) is primarily degraded through the...
Sat Mar 07, 2020 13:28
Related ArticlesThe role of proton therapy in pediatric malignancies: Recent advances and future directions. Semin Oncol. 2020 Feb 21;: Authors: Greenberger BA, Yock TI Abstract Proton radiotherapy has promised an advantage in safely treating pediatric malignancies with an increased capability to spare normal tissues, reducing the risk of both acute and late toxicity. The past decade has seen the proliferation of more than 30 proton facilities in the...
Sat Mar 07, 2020 13:28
Related ArticlesThe changing role of high dose melphalan with stem cell rescue in the treatment of newly diagnosed multiple myeloma in the era of modern therapies-back to the future! Best Pract Res Clin Haematol. 2020 Mar;33(1):101150 Authors: Kazandjian D, Dew A, Hill E Abstract State of the art treatment for myeloma involves using 3-drug combinations incorporating immunomodulatory drugs (IMiDs) and proteasome inhibitors (PIs). Clinical trials for 4-drug...
Sat Mar 07, 2020 13:28
Related ArticlesFrom single gene analysis to single cell profiling: a new era for precision medicine. J Exp Clin Cancer Res. 2020 Mar 05;39(1):48 Authors: Di Martino MT, Meschini S, Scotlandi K, Riganti C, De Smaele E, Zazzeroni F, Donadelli M, Leonetti C, Caraglia M Abstract Molecular profiling of DNA and RNA has provided valuable new insights into the genetic basis of non-malignant and malignant disorders, as well as an increased understanding of basic...
Sat Mar 07, 2020 13:28
Related ArticlesIncidence and time trends of sarcoma (2000-2013): results from the French network of cancer registries (FRANCIM). BMC Cancer. 2020 Mar 06;20(1):190 Authors: Amadeo B, Penel N, Coindre JM, Ray-Coquard I, Ligier K, Delafosse P, Bouvier AM, Plouvier S, Gallet J, Lacourt A, Coureau G, Monnereau A, Mathoulin-Pélissier S, Desandes E Abstract BACKGROUND: The exhaustive collection of new sarcoma cases and their second histologic review offer...
Sat Mar 07, 2020 13:28
Related Articles[Progress on clinical trials of cancer drugs in China, 2019]. Zhonghua Zhong Liu Za Zhi. 2020 Feb 23;42(2):127-132 Authors: Huang HY, Wu DW, Wang HX, Wang J, Fan Q, Wang SH, Bai Y, Yu Y, Fang Y, Sun C, Fang H, Bai H, Wang X, Liu ZY, Jiang M, Liu Z, Wang XH, Li HY, Li N, Cao C, Xu BH, Sun Y, He J Abstract Objective: To deliver macro understanding of the latest research progress on clinical trials and approved products of cancer drugs in...
Sat Mar 07, 2020 13:28
Related ArticlesA new treatment planning approach accounting for prompt gamma range verification and interfractional anatomical changes. Phys Med Biol. 2020 Mar 05;: Authors: Tian L, Landry G, Dedes G, Pinto M, Kamp F, Belka C, Parodi K Abstract Prompt gamma (PG) imaging is investigated for spot-by-spot in-vivo range verification for proton therapy. Previous studies pointed out that the accuracy of PG is affected by the statistics of the beams and the...
Fri Mar 06, 2020 22:36
Related ArticlesPre-treatment serum IL-10 predicts the risk of secondary central nervous system involvement in patients with diffuse large B-cell lymphoma. Cytokine. 2020 Mar 02;129:155048 Authors: Yi JH, Yoon SE, Ryu KJ, Ko YH, Kim WS, Kim SJ Abstract BACKGROUND: As diffuse large B-cell lymphoma (DLBCL) is a very heterogeneous group of lymphomas, much effort has gone in trying to identify patients with increased risk for early death or secondary central...
Fri Mar 06, 2020 22:36
Related ArticlesThe force of HER2 - A druggable target in NSCLC? Cancer Treat Rev. 2020 Feb 28;86:101996 Authors: Jebbink M, de Langen AJ, Boelens MC, Monkhorst K, Smit EF Abstract Since several years targeted therapy has been part of treatment in NSCLC in subsets of patients with specific genetic alterations. One of these alterations involves HER2, a member of the ERBB family of tyrosine kinase receptors. Despite that HER2 alterations in NSCLC have...
Fri Mar 06, 2020 22:36
Related ArticlesSIRT2 protects peripheral neurons from cisplatin-induced injury by enhancing nucleotide excision repair. J Clin Invest. 2020 Mar 05;: Authors: Zhang M, Du W, Acklin SM, Jin S, Xia F Abstract Platinum-based chemotherapy-induced peripheral neuropathy is one of the most common causes of dose reduction and discontinuation of life-saving chemotherapy in cancer treatment; it often causes permanent impairment of quality of life in cancer patients....
Fri Mar 06, 2020 22:36
Related ArticlesSystematic Review of Privacy-Preserving Distributed Machine Learning From Federated Databases in Health Care. JCO Clin Cancer Inform. 2020 Mar;4:184-200 Authors: Zerka F, Barakat S, Walsh S, Bogowicz M, Leijenaar RTH, Jochems A, Miraglio B, Townend D, Lambin P Abstract Big data for health care is one of the potential solutions to deal with the numerous challenges of health care, such as rising cost, aging population, precision medicine,...
Sat Mar 07, 2020 13:28
Related ArticlesHbA1c in patients with intracranial meningiomas WHO grades I and II: A preliminary study. IUBMB Life. 2020 Mar 05;: Authors: Orešković D, Almahariq F, Majić A, Sesar P, Živković M, Maraković J, Marčinković P, Predrijevac N, Vuković P, Chudy D Abstract Meningiomas are among the most common primary brain tumors. There is a growing need for novel ways of differentiating between benign (World Health Organization [WHO] grade I) and atypical...
Fri Mar 06, 2020 22:36
Related ArticlesEthnic Disparities in PET/CT Utilization at Diagnosis of Non-Small Cell Lung Cancer. J Natl Cancer Inst. 2020 Mar 05;: Authors: Morgan RL, Karam SD, Bradley CJ Abstract BACKGROUND: Prior research demonstrated statistically significant racial disparities related to lung cancer treatment and outcomes. We examined differences in initial imaging and survival between Blacks, Hispanics and non-Hispanic Whites. METHODS: The linked Surveillance,...
Fri Mar 06, 2020 22:36
Related ArticlesUnique epidemiological and clinical features of the emerging 2019 novel coronavirus pneumonia (COVID-19) implicate special control measures. J Med Virol. 2020 Mar 05;: Authors: Wang Y, Wang Y, Chen Y, Qin Q Abstract By Feb 27th , 2020, the outbreak of COVID-19 caused 82623 confirmed cases and 2858 deaths globally, more than Severe Acute Respiratory Syndrome (SARS) (8273 cases, 775 deaths) and Middle East Respiratory Syndrome (MERS) (1139...
Fri Mar 06, 2020 22:36
Diagnostic and prognostic value of microRNAs for Alzheimer's disease: a comprehensive meta-analysis.
Related ArticlesDiagnostic and prognostic value of microRNAs for Alzheimer's disease: a comprehensive meta-analysis. Med Pharm Rep. 2020 Jan;93(1):53-61 Authors: Cătană CS, Crişan CA, Opre D, Berindan-Neagoe I Abstract Background and aims: Recent research has shown that microRNAs (miRNAs), a class of sequences regulating gene expression without undergoing translational processes, have been accepted as novel biomarkers of diseases. In the present meta-analysis,...
Fri Mar 06, 2020 22:36
Related ArticlesValidation of Novel Prognostic Biomarkers for Early-Stage Clear-Cell, Endometrioid and Mucinous Ovarian Carcinomas Using Immunohistochemistry. Front Oncol. 2020;10:162 Authors: Engqvist H, Parris TZ, Kovács A, Rönnerman EW, Sundfeldt K, Karlsson P, Helou K Abstract Early-stage (I and II) ovarian carcinoma patients generally have good prognosis. Yet, some patients die earlier than expected. Thus, it is important to stratify early-stage...
Fri Mar 06, 2020 22:36
Related ArticlesObjective response rate assessment in oncology: Current situation and future expectations. World J Clin Oncol. 2020 Feb 24;11(2):53-73 Authors: Aykan NF, Özatlı T Abstract The tumor objective response rate (ORR) is an important parameter to demonstrate the efficacy of a treatment in oncology. The ORR is valuable for clinical decision making in routine practice and a significant end-point for reporting the results of clinical trials. World...
Fri Mar 06, 2020 22:36
Related ArticlesComparative Transcriptomics Analysis of the Responses of the Filamentous Fungus Glarea lozoyensis to Different Carbon Sources. Front Microbiol. 2020;11:190 Authors: Zhang K, Huang B, Yuan K, Ji X, Song P, Ding Q, Wang Y Abstract The natural product pneumocandin B0 is the precursor of the antifungal drug caspofungin. We found that replacing glucose in the initial fermentation medium with 20 g/L fructose is more conducive to pneumocandin...
Fri Mar 06, 2020 22:36
Related ArticlesMachine Learning in Prediction of Second Primary Cancer and Recurrence in Colorectal Cancer. Int J Med Sci. 2020;17(3):280-291 Authors: Ting WC, Lu YA, Ho WC, Cheewakriangkrai C, Chang HR, Lin CL Abstract BACKGROUND: Colorectal cancer (CRC) is the third commonly diagnosed cancer worldwide. Recurrence of CRC (Re) and onset of a second primary malignancy (SPM) are important indicators in treating CRC, but it is often difficult to predict...
Fri Mar 06, 2020 22:36
Related ArticlesAssessment of Distress among Patients and Primary Caregivers: Findings from a Chemotherapy Outpatient Unit. Indian J Palliat Care. 2020 Jan-Mar;26(1):42-46 Authors: Rajeshwari A, Revathi R, Prasad N, Michelle N Abstract Background: Chemotherapy is one of the treatment modalities for cancer. The side effects of treatment, at times, can affect the emotional well-being of patients and their caregivers, thereby leading to distress. This paper...
Fri Mar 06, 2020 22:36
Related ArticlesGenomic-guided precision therapy for soft tissue sarcoma. ESMO Open. 2020 Mar;5(2): Authors: Chen HW, Chen TW Abstract Soft tissue sarcoma (STS), although heterogeneous in histopathology presentation, has mostly been treated with chemotherapy agents as one entity. Our understanding of crucial genomic alterations in different STS histologies and the advent of molecular-targeted agents have reshaped the treatment paradigm for advanced STS....
Fri Mar 06, 2020 22:36
Related ArticlesPrecision oncology in urothelial cancer. ESMO Open. 2020 Mar;5(Suppl 1): Authors: Liow E, Tran B Abstract Genomics-driven, precision medicine has been adopted in virtually every tumour type and underlies the significant advances in cancer management to date. The paradigm shift from the indiscriminate use of chemotherapeutics, to strategies that harness our mechanistic knowledge of cancer biology has led to profound clinical benefit for...
Fri Mar 06, 2020 22:36
Related ArticlesCommunication about the desire to die: Development and evaluation of a first needs-oriented training concept - A pilot study. Palliat Support Care. 2020 Mar 05;:1-9 Authors: Frerich G, Romotzky V, Galushko M, Hamacher S, Perrar KM, Doll A, Montag T, Golla H, Strupp J, Kremeike K, Voltz R Abstract OBJECTIVE: Patients' desire to die (DD) is rarely discussed in palliative care (PC) due to health professionals' (HPs) feeling of uncertainty....
Fri Mar 06, 2020 22:36
Related ArticlesSerum miRNAs, a potential prognosis marker of loco-regionally advanced nasopharyngeal carcinoma patients treated with CCRT. BMC Cancer. 2020 Mar 04;20(1):183 Authors: Zhang Z, Huang J, Wang G, Jin F, Zheng J, Xiao H, Lei L, Luo J, Chen C Abstract BACKGROUND: Serum miRNA was once found as potential disease survival index,thus we investigated the role of miRNA in predicting prognosis in loco-regionally advanced NPC patients treated with...
Fri Mar 06, 2020 22:36
Related ArticlesTargeting Mitochondrial Apoptosis to Overcome Treatment Resistance in Cancer. Cancers (Basel). 2020 Mar 02;12(3): Authors: Ngoi NYL, Choong C, Lee J, Bellot G, Wong ALA, Goh BC, Pervaiz S Abstract Deregulated cellular apoptosis is a hallmark of cancer and chemotherapy resistance. The B-cell lymphoma 2 (BCL-2) protein family members are sentinel molecules that regulate the mitochondrial apoptosis machinery and arbitrate cell fate through...
Fri Mar 06, 2020 22:36
Genetic and Pharmacological Targeting of Heat Shock Protein 70 in the Mouse Amygdala-Kindling Model.
Related ArticlesGenetic and Pharmacological Targeting of Heat Shock Protein 70 in the Mouse Amygdala-Kindling Model. ACS Chem Neurosci. 2019 03 20;10(3):1434-1444 Authors: von Rüden EL, Wolf F, Gualtieri F, Keck M, Hunt CR, Pandita TK, Potschka H Abstract Inflammatory responses involving Toll-like receptor signaling represent a key factor contributing to epileptogenesis. Thus, it is of particular interest to explore the relevance of toll-like receptor...
Fri Mar 06, 2020 22:36
Related ArticlesCorrection: Association of baseline inflammatory biomarkers with cancer mortality in the REGARDS cohort. Oncotarget. 2020 Feb 18;11(7):758 Authors: Akinyemiju T, Moore JX, Dibaba DT, Pisu M, Goodman M, Howard VJ, Safford M, Gilchrist SC, Cushman M, Long L, Judd SE Abstract [This corrects the article DOI: 10.18632/oncotarget.27108.].PMID: 32133050 [PubMed - in process]
Fri Mar 06, 2020 23:12
Related ArticlesCorrection: AMF/PGI-mediated tumorigenesis through MAPK-ERK signaling in endometrial carcinoma. Oncotarget. 2020 Feb 18;11(7):755-757 Authors: Li Y, Jia Y, Che Q, Zhou Q, Wang K, Wan XP Abstract [This corrects the article DOI: 10.18632/oncotarget.4708.].PMID: 32133049 [PubMed - in process]
Fri Mar 06, 2020 23:12
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