Purpose: Self-inflicted facial gunshots (SIGSWs) typically result in a spectrum of severe injuries to facial structures, including the orbit and globe. Roughly three-quarters of those who arrive to the hospital will survive their injuries, and recidivism is typically low. Therefore, effective management is paramount to preserve vision, and long-term quality of life. The objective of this study is to characterize the common injuries to the orbit, globe, and periocular structures following SIGSWs,...
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Purpose: Although it is a commonly held belief that stretching of the optic nerve is important in dysthyroid optic neuropathy (DON), it is probably mainly due to microvascular ischemia arising from high pressure at the orbital apex. If stretch is important in DON, one would expect longer optic nerves and reduced optic nerve compliance in these patients. Methods: Retrospective comparative case series for 75 patients with DON, and for age- and sex-matched control patients with thyroid eye disease...
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Purpose: To retrospectively describe the clinical characteristics, management, and outcomes of a series of patients with solitary fibrous tumor (SFT) of the orbit and to evaluate signal transducer and activator of transcription 6 (STAT6) as a diagnostic marker. Methods: Review of a retrospective, noncomparative, consecutive series of patients treated at a single institution with a histopathologic diagnosis of SFT. Demographic, clinical, and imaging data were collected, and paraffin-embedded...
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Purpose: To evaluate the effects of cigarette smoking on oxidative stress (OS) and mitochondrial biogenesis related parameters in patients Graves Ophthalmopathy (GO). Methods: Patients with moderate-to-severe GO according to the European Group on Graves Orbitopathy (EUGOGO) criteria were prospectively enrolled in this study. Age- and sex-matched healthy volunteers who applied to outpatient clinic due to refractive problems consisted the control group. Participants were divided into 4 groups...
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Purpose: To determine if crowdsourced ratings of oculoplastic surgical outcomes provide reliable information compared to professional graders and oculoplastic experts. Methods: In this prospective psychometric evaluation, a scale for the rating of postoperative eyelid swelling was constructed using randomly selected images and topic experts. This scale was presented adjacent to 205 test images, including 10% duplicates. Graders were instructed to match the test image to the reference image...
Kabuki syndrome (KS) is a rare congenital disorder characterized by multiple systemic anomalies and facial characteristics. Here, the authors present the first case, to the best of the authors' knowledge, of bilateral lacrimal puncta agenesis in a patient with KS.#8232;The proband patient was a 29-year-old woman diagnosed with this syndrome, brought to our office due to recurrent conjunctivitis where agenesia of lacrimal puncta was observed. Therapeutic options were exposed but, as the concomitant...
Purpose: To analyze and quantify the characteristics and parameters of the eyelid and adnexa of males and females and correlate these findings to an aesthetically pleasing score. Methods: This is an Institutional Review Board approved study involving healthy male and female volunteers. The margin-to-reflex distance, palpebral fissure, inferior scleral show, tarsal platform show, and brow fat span were measured using Image J digital photographic analysis and the images were scored by 110 non-ophthalmologists....
A 37-year-old male was found to have a firm yellowy-white palpable mass embedded within the conjunctival surface of the tarsal plate of the left upper eyelid. This was asymptomatic and noted on a routine examination for contralateral epiphora. An excisional biopsy was performed and a “rock-like nodule” was removed with histopathology confirming the presence of mature bone. While the literature describes these lesions located in other aspects of the orbit, this is the first described case of an epibulbar...
Purpose: To describe the clinicopathologic characteristics and the expression of diagnostic/treatment targets in ocular adnexal Kaposi Sarcoma. Methods: We conducted a clinical-pathologic retrospective case series. Immunohistochemical staining for cluster of differentiation 31 (CD31), human herpesvirus-8 (HHV8), platelet-derived growth factor receptor alpha (PDGFR-A), vascular endothelial growth factor receptor-1 (VEGF), tyrosine-protein kinase Kit (c-Kit), and programmed cell death protein...
The authors present a case of an eyelid eccrine porocarcinoma, a very rare malignant sweat gland tumor characterized histopathologically by nests of atypical poromatous cells and the presence of duct-like lumina. Histopathologic analysis of this case also exhibited numerous loose tumor cells in the adjacent tear film, a finding that has not been previously described.
Purpose: To evaluate the ability of preoperative phenylephrine testing to predict postoperative upper eyelid tarsal platform show in patients undergoing Müller muscle–conjunctival resection (MMCR) ptosis repair without concurrent blepharoplasty. Methods: A retrospective chart review was performed on 52 eyelids of patients who underwent MMCR without external skin incision. Photographs were reviewed to objectively and subjectively compare the results of phenylephrine testing to postoperative...
Basal cell carcinoma accounts for 90% of malignant tumors of the eyelid. Basal cell carcinoma has been reported to rarely occur in conjunction with osteoma cutis or bone formation in the skin. The mechanism of this secondary osteoma cutis has yet to be explained. Herein, the authors present the case of a 68-year-old woman with a rapidly enlarging basal cell carcinoma with secondary osteoma cutis of the left lower eyelid.
Purpose: To determine whether thyroid eye disease (TED) is associated with a change in temporal fossa soft tissue volume. Methods: CT imaging studies were selected from patients with TED considering orbital decompression surgery and from an age-matched group of controls presenting to the Emergency Department for nontraumatic conditions requiring CT imaging. Measurements of the temporal fossa fat pad and soft tissue thickness were used as a proxy for volume and were performed using the zygomaticotemporal...
As intraoperative use of electronic equipment becomes more common, familiarity with the potential for electrocardiographic artifact generated by these instruments is increasingly important. The authors' patient underwent endoscopic dacryocystorhinostomy under general anesthesia for treatment of acute on chronic dacryocystitis secondary to acquired nasolacrimal duct obstruction. She had previously had pacemaker placement for treatment of sick sinus syndrome and low ejection fraction heart failure,...
Purpose: To demonstrate the utility of an ultrasonic aspirator (Sonopet, Stryker Corporation; Kalamazoo, MI) for debulking firm, soft tissue masses of the orbit. Methods: Case series. The ultrasonic aspirator was used to debulk firm, soft tissue masses in 3 cases. The initial patient had a large orbitofacial mass extending to the inferior and lateral orbital apex secondary to IgG4 disease. The second patient had a lacrimal sac adenocarcinoma extending to the medial orbital apex. The third...
Proptosis is a common yet cardinal symptom that may indicate the development of a wide range of diseases. Causes of proptosis are usually classified into vascular, inflammatory, endocrine, and neoplastic. Herein, the authors describe a case where proptosis manifested as the primary and only symptom of a massive brain arteriovenous malformation. Deprived of any other conventional symptoms and signs of a brain arteriovenous malformation, such as headaches, nausea, vision loss, increased ocular pressure,...
Purpose: To describe a novel pedicled temporo-parietal flap to delay laminar resorption in a modified osteo-odonto keratoprosthesis (MOOKP) and measure resorption of the dental lamina by an objective method. Methods: A retrospective case series was performed on patients who received an osteo-odontokeratoprosthesis for Steven-Johnson-Syndrome. Surgeries were performed between October 2016 and November 2017 by the same surgical team (G.M. and S.W.). A modified temporo-parietal flap was incorporated...
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A ruby-throated hummingbird dips into a nectar feeder. An East Coast favorite, the species can be harmed by yard predators like praying mantises and bacteria in unclean equipment. (Jeremy Lwanga/Unsplash/)Julian Avery is an assistant research professor of wildlife ecology and conservation at Pennsylvania State University. This story originally featured on The Conversation.Millions of Americans enjoy feeding and watching backyard birds. Many people make a point of putting food out in winter, when...
When NASA mathematician Katherine Johnson retired in 1986, she’d spent three-plus decades at the agency and only seen a handful of American women go into space. One, of course, was Sally Ride in 1983; the second was Judith Resnik, who died in the Space Shuttle Challenger disaster. But it wasn’t for a lack of potential. “Girls are capable of doing everything men are capable of doing,” Johnson said in an interview years later. “Sometimes they have more imagination than men.”Though Johnson knew this...
Annie Jump Cannon joined the Harvard Observatory in 1896 to help build the official classification system for stars. Her calculations were largely drawn off the atmospheric refraction in telescopic photos rather than in situ observations; she and her fellow female colleagues earned about half of the men in their positions. The university didn't designate Cannon as an astronomer until near the end of her career in 1938. (Smithsonian Institution/)Mary Golda Ross led an entire life before turning her...
Not even the ocean's deepest dwellers are immune to climate change. (NOAA/)The fish that live at the bottom of the sea are a hardy bunch. They’re adapted to handle crushing pressure, little to no sunlight, and a meager supply of food. But these otherwise gritty fish are also very sensitive to changes in the climate of the water around them, a new study suggests.Scientists surveyed different patches of seafloor in the Gulf of California and saw that variations in temperature and oxygen levels had...
The cookies on your computer don't look like this. Unless you're looking at this on a computer. Then there are cookies on your computer that look like this. But this story isn't about these types of cookies. (Alex via Unsplash/)Dive into your web browser’s settings and you’ll see references to cookies—little bits of data that have been around almost as long as browser apps themselves. Now, browsers are going to war against them, and it’s going to affect you.Earlier this year, Google announced it...
A bipartisan deal would fully fund the LWCF and provide more than $1 billion per year for clearing the maintenance backlogs in our national parks. (NPS.Gov/)This story originally featured on Outdoor Life.President Donald Trump has evidently undergone an election-year conversion on the topic of the Land & Water Conservation Fund (LWCF), pumping new energy into the campaign for full and permanent funding of this critically important access and habitat conservation tool.This week, Trump used his...
Doesn't this four-seater look fun to take to the super market? (koenigsegg/)The spread of COVID-19 put the brakes on this year’s Geneva International Motor show. The event typically is a showcase for new models and futuristic concepts that hint at the future of life on the road. While the actual event didn’t happen, those new rides still exist, however, and there’s some very cool tech inside them. We’ve gathered up some of the most interesting and promising whips from this year’s Geneva for you to...
Cosmos: Possible Worlds finds hope for humanity’s future in stories from its past. (Cosmos Studios/)Since 1980s, the television show Cosmos has woven together threads from physics, astronomy, neuroscience, ecology, and other fields while teaching and entertaining along the way. It’s a daunting challenge, but one that the show’s writer and executive producer, Ann Druyan, relishes. She’s been deeply involved in the program since its original incarnation, Cosmos: A Personal Voyager, which she co-wrote...
We'll cover latte art in a different chapter. (Jess Eddy via Unsplash/)There’s no excuse for making bad coffee at home (unless you’re using instant grounds). With the right gear and a bit of experimentation, you can reliably brew a better cup than most cafés. It just takes a bit of research upfront to work out what you like, some practice to dial in the technique, and you’re good to go.It’s all about the beans“The quality of coffee you start with sets the limit for how good your coffee can be,” says...
After permafrost at Gates of the Arctic National Park thawed, the landscape changed, allowing the Okokmilaga River to flow to the sea. (National Park Service Climate Change Response/)This story was published in partnership with Nexus Media, a syndicated newswire covering climate, energy, policy, art, and culture.For decades, the Inuit woman, a victim of the 1918 Spanish flu, lay buried in a mass grave under six feet of Alaskan permafrost. But when the frozen ground began to thaw in the 1990s, the...
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The incorporation of digital health technologies (DHT) has gained significant traction within healthcare organizations as it promises to support patients and healthcare professionals to optimize the provision of care and self-management in a personalized manner, particularly in chronic diseases. Yet, recent systematic reviews have found there is no significant evidence demonstrating that Digital Health improves the management of chronic diseases such as chronic obstructive pulmonary disease (COPD).1...
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Related ArticlesFDG PET/CT of COVID-19. Radiology. 2020 Mar 06;:200770 Authors: Zou S, Zhu X PMID: 32142399 [PubMed - as supplied by publisher]
Related ArticlesPatients with RT-PCR Confirmed COVID-19 and Normal Chest CT. Radiology. 2020 Mar 06;:200702 Authors: Yang W, Yan F PMID: 32142398 [PubMed - as supplied by publisher]
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Technology in Cancer Research &Treatment, Volume 19, Issue , January-December 2020. Background and Aim:Although the prognosis of nasopharyngeal cancer largely depends on a classification based on the tumor-lymph node metastasis staging system, patients at the same stage may have different clinical outcomes. This study aimed to evaluate the survival prognosis of nasopharyngeal cancer using machine learning.Settings and Design:Original, retrospective.Materials and Methods:A total of 72 patients...
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Chronic Respiratory Disease, Volume 17, Issue , January-December 2020. Recent studies have suggested that an increased peripheral monocyte count predicts a poor outcome in fibrosing interstitial lung disease (ILD). However, the association between an increased monocyte count and acute exacerbations (AEs) of fibrosing ILD remains to be elucidated. Our retrospective cohort study aimed to assess the impact of peripheral monocyte count on AEs of fibrosing ILD. We analyzed the electronic medical records...
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