Abstract Aborting a neurosurgical procedure is a situation in which the surgeon modifies the original surgical plan and decides to stop a procedure without achieving the pre-operative goal. While adhering to predefined goals is important, intra-operative judgment, especially in terms of adjusting the risk/benefit ratio in response to real-time data, may change the balance and lead, in selective scenarios, to aborting of a procedure. The literature regarding aborting a surgical...
Fri Mar 06, 2020 02:00
The original version of this article unfortunately contained an error. The author apologizes for having communicated an interchanged author’s first and family names. Given in this article are the correct author names.
Fri Mar 06, 2020 02:00
Publication date: Available online 6 March 2020Source: Clinical TherapeuticsAuthor(s): Megan L. Evans, Alyson J. McGregor
Sat Mar 07, 2020 11:22
Publication date: Available online 5 March 2020Source: Clinical TherapeuticsAuthor(s): Rachel Shireen Golpanian, Hei Sung Kim, Gil Yosipovitch
Fri Mar 06, 2020 17:18
Publication date: Available online 5 March 2020Source: Clinical TherapeuticsAuthor(s): Bethany R. Shoulders, Anthony M. Casapao, Veena Venugopalan
Fri Mar 06, 2020 17:18
Publication date: Available online 5 March 2020Source: Clinical TherapeuticsAuthor(s): Ana I. Plácido, Maria Teresa Herdeiro, Manuel Morgado, Adolfo Figueiras, Fátima Roque
Fri Mar 06, 2020 17:18
Sat Mar 07, 2020 10:31
Fri Mar 06, 2020 22:44
Fri Mar 06, 2020 22:44
Abstract Objective To characterize trajectories of normative cognitive aging Methods Older persons without dementia at study enrollment (n = 1,010) had annual cognitive testing for up to 24 years (mean = 9.9 years, SD = 5.0), died, and underwent a neuropathologic examination to quantify 9 postmortem markers of common neurodegenerative and cerebrovascular conditions. To accommodate the heterogeneity in cognitive trajectories, we used functional mixed effects models which allow individuals...
Sat Mar 07, 2020 05:33
Starting on Monday, March 9, and continuing until further notice, we are changing our clinic admission procedure because of the coronavirus disease outbreak. Your appointment may be affected. The post IMPORTANT NOTICE TO PATIENTS appeared first on UW School of Dentistry.
Sat Mar 07, 2020 02:27
Abstract Following an application from BioGaia AB submitted for authorisation of a health claim pursuant to Article 13(5) of Regulation (EC) No 1924/2006 via the Competent Authority of Sweden, the EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA) was asked to deliver an opinion on the scientific substantiation of a health claim related to orodispersible lozenges containing a combination of Lactobacillus reuteri DSM 17938 and Lactobacillus reuteri ATCC PTA 5289 and normal gum function....
Sat Mar 07, 2020 02:31
Abstract Following a request from the European Commission, the EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA) was asked to deliver an opinion on chromium‐enriched biomass of Yarrowia lipolytica as a novel food (NF) pursuant to Regulation (EU) 2015/2283. The NF is the dried and heat‐killed chromium‐enriched biomass of Y. lipolytica. This yeast species is widespread in nature, can be found in the environment and in foods, and was attributed the qualified presumption of safety (QPS)...
Sat Mar 07, 2020 02:31
Abstract Rift Valley fever (RVF) is a vector‐borne disease transmitted by a broad spectrum of mosquito species, especially Aedes and Culex genus, to animals (domestic and wild ruminants and camels) and humans. Rift Valley fever is endemic in sub‐Saharan Africa and in the Arabian Peninsula, with periodic epidemics characterised by 5–15 years of inter‐epizootic periods. In the last two decades, RVF was notified in new African regions (e.g. Sahel), RVF epidemics occurred more frequently and low‐level...
Sat Mar 07, 2020 02:31
Abstract The food enzyme α‐amylase (4‐a‐d‐glucan glucanohydrolase; EC 3.2.1.1) is produced with the genetically modified Pseudomonas fluorescens strain BD15754 by BASF Enzymes LLC1. The food enzyme is free from viable cells of the production organism and recombinant DNA. The α‐amylase is intended to be used in distilled alcohol production and starch processing for the production of glucose syrups. Residual amounts of total organic solids (TOS) are removed by distillation and by the purification...
Sat Mar 07, 2020 02:31
Abstract The EFSA Panel on Plant Health performed a pest categorisation of Nemorimyza maculosa (Malloch) (Diptera: Agromyzidae) for the European Union (EU). N. maculosa is an oligophagous pest; cultivated hosts include Chrysanthemum, lettuce and other Asteraceae although there is little evidence of recent impacts. N. maculosa occurs widely in the Americas and is present on the island of Madeira (Portugal), where it is under official control. N. maculosa is not known to occur in mainland Portugal...
Sat Mar 07, 2020 02:31
Abstract The conclusions of EFSA following the peer review of the initial risk assessments carried out by the competent authority of the initial rapporteur Member State the United Kingdom and the new rapporteur Member State Italy for the pesticide active substance chloropicrin are reported. The context of the peer review was that required by Regulation (EC) No 1107/2009 of the European Parliament and of the Council. The conclusions were reached on the basis of the evaluation of the representative...
Sat Mar 07, 2020 02:31
Sat Mar 07, 2020 02:03
Sat Mar 07, 2020 02:03
This study presents a local series of consecutive hybrid laparoscopic pancreaticoduodenectomy (LPD) and a suggested protocol for implementation of an LPD programme in Australian and New Zealand settings. Hybrid LPD is associated with satisfactory perioperative outcomes and may be feasible as a first step towards eventual implementation of LPD in Australian and New Zealand hospitals. Abstract Background Laparoscopic pancreaticoduodenectomy (LPD) is gaining interest with several series reporting...
Sun Mar 08, 2020 13:00
Pre‐operative interleukin‐6 was an independent risk factor for sepsis following pancreaticoduodenectomy. The full model including all predictors mentioned above showed a C‐index of 0.831 and blood transfusion showed no statistically significance in this model. The reduced model 2 could be used for early sepsis assessment and this model showed a C‐index of 0.814. Abstract Background Sepsis is a common complication following pancreaticoduodenectomy (PD). The aim of this study was to evaluate...
Sun Mar 08, 2020 13:00
The preoperative Raja Isteri Pengiran Anak Saleha Appendicitis scores and preoperative ultrasonography results of the patients who were operated in our clinic with an initial diagnosis of acute appendicitis were compared to the histopathological examination results of their appendectomy materials and the results obtained were discussed also referring to the literature data. Abstract Background The diagnosis of acute appendicitis is a clinical challenge. Clinical scoring systems and radiological...
Sun Mar 08, 2020 13:00
Fri Mar 06, 2020 17:53
We report a reconstruction method to achieve high spatial resolution for hyperspectral imaging of chromophore features in skin in vivo. The method utilizes an established structure‐adaptive normalized convolution algorithm to reconstruct high spatial resolution of hyperspectral images from snapshot low‐resolution hyperspectral image sequences captured by a snap‐shot spectral camera. The reconstructed images at chromophore‐sensitive wavebands are used to map the skin features of interest. We demonstrate...
Sat Mar 07, 2020 01:59
Abstract Effective intraoperative tumor margin assessment is needed to reduce re‐excision rates in breast‐conserving surgery (BCS). Mapping the attenuation coefficient in optical coherence tomography (OCT) throughout a sample to create an image (attenuation imaging) is one promising approach. For the first time, three‐dimensional OCT attenuation imaging of human breast tissue micro‐architecture using a wide‐field (up to ~45 × 45 × 3.5 mm) imaging system is demonstrated. Representative results from...
Sat Mar 07, 2020 01:59
We develop a novel smartphone‐based spectral imaging otoscope for telemedicine and examine its capability for the mobile diagnosis of middle ear diseases. The device was applied to perform spectral imaging and analysis of an ear‐mimicking phantom and a normal and abnormal tympanic membrane for evaluation of its potential for the mobile diagnosis. Spectral classified images were obtained via on‐line spectral analysis in a remote server. The phantom experimental results showed that it allowed us to...
Sat Mar 07, 2020 01:59
Raman spectroscopy was employed as a nondestructive technique for the analysis of dry traces of oral fluid to differentiate between smoker and nonsmoker donors with the aid of advanced statistical tools. A genetic algorithm (GA) was used to determine eight spectral regions that contribute the most to the differentiation of smokers and nonsmokers. Thereafter, a classification model was developed based on the artificial neural network (ANN) that showed 100% accuracy after external validation. (Image...
04:19
iSERS (SERS=surface‐enhanced Raman scattering) microscopy is an emerging Raman‐based staining technique for the selective localization of target proteins on cells and tissues using antibody‐ SERS nanotag conjugates. In this contribution we demonstrate the feasibility of iSERS for imaging of programmed cell death‐ligand 1 (PD‐L1), an important predictive biomarker, on single SkBr‐3 breast cancer cells. Further details can be found in the article by Elzbieta Stepula, Matthias König, Xin‐Ping Wang,...
04:19
This study presents a novel intraoperative in vivo imaging approach which harnessed Cerenkov luminescence (CL) to detect primary and metastatic colorectal cancer (CRC) using clinically approved radiopharmaceuticals. In the mice and swine experiments, the proposed approach effectively improved the effect of CRC surgery. The approach is believed to be promising for utilizing CL in open surgery. Further details can be found in the article by Zeyu Zhang, Yawei Qu, Yu Cao et al. (e201960152) Abstract...
04:19
Abstract Objectives Using stable isotope analysis of incremental dentin segments, we reconstruct breastfeeding, weaning, and childhood dietary patterns of Eastern Zhou period (771–221 BC) individuals from the Central Plains of China. Previous isotopic research on the Eastern Zhou demonstrated dietary difference between male and female diets in adulthood via bone collagen analysis. To understand the development of gendered dietary patterns we must examine the early life period. We aim to identify...
Sat Mar 07, 2020 01:15
Abstract Objectives The Y chromosome has highly informative markers, such as single‐nucleotide polymorphisms (SNPs), that are useful for making historical inferences about the settlement of the Americas. However, the scarcity of these markers has limited their use. This study aims to identify new SNPs and increase the phylogenetic resolution of haplogroup Q for the Americas, mainly focusing on the lineages of the Amazon region. Materials and Methods Next‐generation sequencing was...
Sat Mar 07, 2020 01:15
Abstract Objectives The presence of kin is often, but not always, associated with higher fertility in historical populations. However, the effect of other household members on fertility is less frequently studied. While not genetically related, life‐cycle servants lived and worked alongside household members and may have provided assistance to reproducing families. Female servants in particular may have helped mothers with small children through direct help with childcare activities or by...
Sat Mar 07, 2020 01:15
Abstract Objective Frequency‐dependent selection is expected to maintain infant sex ratios around parity over evolutionary time. However, over ecological time periods, infant sex ratios vary, and it has been proposed that this variation may reflect adaptive processes. In primates, there are consistent patterns of variation in infant sex ratios, although their adaptive significance remains contentious. In addition to design issues, contrasting results could have derived across primates from...
Sat Mar 07, 2020 01:15
Abstract Lynch syndrome (LS) is characterised by predisposition to colorectal, endometrial and other cancers and is caused by inherited pathogenic variants affecting the DNA mismatch repair (MMR) genes MLH1, MSH2, MSH6 and PMS2. It is probably the most common predisposition to cancer, having an estimated prevalence of between 1/100 and 1/180. Resources such as the International Society for Gastrointestinal Hereditary Cancer's MMR gene variant database, the Prospective Lynch Syndrome Database (PLSD)...
Sat Mar 07, 2020 01:13
A clear bone margin is essential for complete resection of the bone-involved tumour, but the evaluation of hard tissue takes time and is impractical intraoperatively. Bone marrow assessment remains controversial. The aim of this study was to investigate the diagnostic value of intraoperative bone marrow assessment for bone margins. PubMed and Web of Science were searched for studies published between 1990 and 2017. A systematic review was conducted. After quality assessment, 10 articles with 11 cohorts...
Fri Mar 06, 2020 02:00
Related ArticlesThe effect of alveolar decortication on orthodontically induced root resorption. Angle Orthod. 2020 Mar 05;: Authors: Chen PJ, Chang JH, Dutra EH, Ahmida A, Nanda R, Yadav S Abstract OBJECTIVE: To determine the effect of alveolar decortication on orthodontically induced root resorption. MATERIALS AND METHODS: A total of 24 male Wistar rats (14 week old) were used. The rats were randomly divided into one of the following three...
Fri Mar 06, 2020 23:16
Related ArticlesThe Class II Carriere Motion appliance: A 3D CBCT evaluation of the effects on the dentition. Angle Orthod. 2020 Mar 05;: Authors: Areepong D, Kim KB, Oliver DR, Ueno H Abstract OBJECTIVES: To determine three-dimensional treatment changes produced by the Class II Carriere Motion appliance (CMA) in Class II adolescent patients with Class I and Class II skeletal relationships. MATERIALS AND METHODS: The sample included 59 adolescents...
Fri Mar 06, 2020 23:16
Related ArticlesBone-anchored maxillary protraction in patients with unilateral cleft lip and palate: Is maxillary expansion mandatory? Angle Orthod. 2020 Mar 05;: Authors: Elabbassy EH, Sabet NE, Hassan IT, Elghoul DH, Elkassaby MA Abstract OBJECTIVES: To assess the effectiveness of bone-anchored maxillary protraction (BAMP) in patients with unilateral cleft lip and palate (UCLP) and whether it was enhanced when preceded by maxillary expansion. ...
Fri Mar 06, 2020 23:16
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