Related ArticlesmiR-22 inhibition reduces hepatic steatosis via FGF21 and FGFR1 induction. JHEP Rep. 2020 Apr;2(2):100093 Authors: Hu Y, Liu HX, Jena PK, Sheng L, Ali MR, Wan YY Abstract Background & Aims: Metabolism supports cell proliferation and growth. Surprisingly, the tumor suppressor miR-22 is induced by metabolic stimulators like bile acids. Thus, this study examines whether miR-22 could be a metabolic silencer. Methods: The relationship...
Sat Mar 21, 2020 13:50
Related ArticlesAssociations Between the Triglyceride to High-Density Lipoprotein Cholesterol Ratio and Metabolic Syndrome, Insulin Resistance, and Lifestyle Habits in Healthy Japanese. Metab Syndr Relat Disord. 2020 Mar 19;: Authors: Moriyama K Abstract Background: The triglyceride (TG)/high-density lipoprotein cholesterol (HDL-C) ratio is related to insulin resistance (IR). However, little information is available on whether TG/HDL-C is associated...
Fri Mar 20, 2020 15:15
Related ArticlesA fulvic acid-like substance participates in the pro-inflammatory effects of cigarette smoke and wood smoke particles. Chem Res Toxicol. 2020 Mar 19;: Authors: Gonzalez DH, Soukup JM, Madden MC, Hays MD, Berntsen J, Paulson SE, Ghio AJ Abstract We tested the postulate that 1) a fulvic acid (FA)-like substance is included in cigarette smoke and wood smoke particle (WSP) and 2) cell exposure to this substance results in a disruption of...
Fri Mar 20, 2020 15:15
Related ArticlesCompliance and Practical Utility of Continuous Wearing of activPAL™ in Adolescents. Pediatr Exerc Sci. 2019 08 01;31(3):363-369 Authors: Shi Y, Huang WY, Yu JJ, Sheridan S, Sit CH, Wong SH Abstract PURPOSE: The aim of this study was to examine the factors that influence compliance and practical utility of a continuous wear protocols for activPAL™ among adolescents. METHODS: Seven hundred and fifty-five (11-18 y; 50.6% girls)...
Fri Mar 20, 2020 13:12
Background. The enlargement of lymph nodes is a common clinical sign in connective tissue disease (CTD) and viral hepatitis. In this research, we evaluated the incidence of enlarged lymph nodes in autoimmune liver diseases (AILD). Moreover, we identified the clinical significance of abdominal lymph node enlargement in AILD. Methods. The characteristics of abdominal lymph nodes, including their morphology and distribution, were assessed by ultrasonography and computed tomography in 125 patients with...
Sat Mar 21, 2020 09:20
Summary Background Recurrent mucocutaneous infections caused by PVL‐positive Staphylococcus (S.) aureus strains represent an increasing problem in Germany. Although there have been several outbreaks at day care centers and in urban communities in recent years, there are currently no diagnostic algorithms or treatment recommendations for these particular infections in Germany. Methods We performed a literature search in the PubMed/MEDLINE database with the goal of developing an algorithm...
Sat Mar 21, 2020 13:28
Sat Mar 21, 2020 13:28
Abstract Purpose of Review Diverse musculoskeletal disorders and neuropathic symptoms of the face pose significant diagnostic challenges. In particular, temporal tendinosis is generally overlooked in the medical and dental literature and is therefore a poorly understood topic and often problematic cause of chronic orofacial pain. In this article, we explore temporal tendinosis as a cause of unresolved orofacial pain by reviewing...
Sat Mar 21, 2020 02:00
Abstract Purpose of Review Sickle cell disease (SCD) is a hematological disorder which leads to serious complications in multiple organ systems. While significant research has addressed many of the effects of acute pain episodes and end-organ damage connected to this disease, little has approached the chronic pain state associated with this condition. Recent...
Sat Mar 21, 2020 02:00
Abstract Purpose of Review Migraine headaches are a neurologic disorder characterized by attacks of moderate to severe throbbing headache that are typically unilateral, exacerbated by physical activity, and associated with phonophobia, photophobia, nausea, and vomiting. In the USA, the overall age-adjusted prevalence of migraine in female and male adults is 22.3% and 10.8%, respectively. ...
Sat Mar 21, 2020 02:00
Abstract Purpose of Review Point of care ultrasound (POCUS) has played a role across almost every medical specialty. Although anesthesiologists have been using bedside ultrasound for nerve blocks and vascular access for many years now, there has been a recent push to incorporate whole-body POCUS into anesthesiologists’ training and daily practice. This article provides a brief overview of the indications, techniques for image...
Sat Mar 21, 2020 02:00
Abstract Purpose of Review This comprehensive review of current concepts in the management of vertebral compression fractures is a manuscript of vertebral augmentation literature of risk factors, clinical presentation, and management. The objective of this review is to compare outcomes between multiple augmentation techniques and ongoing discussions of effectiveness of vertebral augmentation procedures. ...
Fri Mar 20, 2020 02:00
Related ArticlesPrednisolone suppresses the immunostimulatory effects of 27-hydroxycholesterol. Exp Ther Med. 2020 Mar;19(3):2335-2342 Authors: Kim BY, Son Y, Kim MS, Kim K Abstract In cholesterol-fed rabbits, site-specific targeting of prednisolone nanoparticles results in significantly reduced neo-intimal inflammation with a decreased infiltration of monocytes/macrophages. To understand the molecular mechanisms underlying this, the current study investigated...
Sat Mar 21, 2020 13:26
Related ArticlesUpdates on larynx cancer epidemiology. Chin J Cancer Res. 2020 Feb;32(1):18-25 Authors: Nocini R, Molteni G, Mattiuzzi C, Lippi G Abstract Objective: Laryngeal cancer is an important oncologic entity, whose prognosis depends on establishing appropriate preventive and diagnostic measures, especially in populations at higher risk. Methods: Epidemiologic information including worldwide incidence, prevalence, burden of health loss...
Sat Mar 21, 2020 13:22
Related ArticlesSystematic review and meta-analysis of T1 glottic cancer outcomes comparing CO2 transoral laser microsurgery and radiotherapy. J Otolaryngol Head Neck Surg. 2019 Sep 03;48(1):44 Authors: Vaculik MF, MacKay CA, Taylor SM, Trites JRB, Hart RD, Rigby MH Abstract BACKGROUND: The objective of this study is to compare the oncologic outcomes of CO2 transoral laser microsurgery (TLM) and radiotherapy (RT) for treatment of T1 glottic carcinoma....
Sat Mar 21, 2020 13:22
Related ArticlesHarmonization of proton treatment planning for head and neck cancer using pencil beam scanning: first report of the IPACS collaboration group. Acta Oncol. 2019 Dec;58(12):1720-1730 Authors: Stock M, Gora J, Perpar A, Georg P, Lehde A, Kragl G, Hug E, Vondracek V, Kubes J, Poulova Z, Algranati C, Cianchetti M, Schwarz M, Amichetti M, Kajdrowicz T, Kopeć R, Mierzwińska G, Olko P, Skowrońska K, Sowa U, Góra E, Kisielewicz K, Sas-Korczyńska B, Skóra T, Bäck...
Sat Mar 21, 2020 13:22
Related ArticlesBilateral Selective Laryngeal Reinnervation for Bilateral Vocal Fold Paralysis in Children. JAMA Otolaryngol Head Neck Surg. 2020 Mar 19;: Authors: Lee JW, Bon-Mardion N, Smith ME, Marie JP Abstract Importance: Bilateral vocal fold paralysis (BVFP) in pediatric patients is a challenging entity with multiple causes. Traditional approaches to managing BVFP include tracheostomy, arytenoidectomy, suture lateralization, cordotomy, and posterior...
Fri Mar 20, 2020 14:52
Related ArticlesAdenosquamous carcinoma of the tongue: A case report and an overview of histogenetic concepts. J Oral Maxillofac Pathol. 2020 Feb;24(Suppl 1):S110-S114 Authors: Prabhakar M, Sabarinath B, Sivapathasundharam B, Vasanthakumar V Abstract Adenosquamous carcinoma (ASC), a rare variant of squamous cell carcinoma, is an aggressive and highly infiltrating epithelial neoplasm, which has a distinct histomorphological features comprising simultaneous...
Fri Mar 20, 2020 14:52
Related ArticlesThe laryngeal twitch response - Can it avoid unnecessary two-stage thyroidectomy? - A retrospective cohort study. Int J Surg. 2019 Dec;72:130-134 Authors: Gschwandtner E, Netz J, Passler C, Bobak-Wieser R, Göbl S, Tatzgern E, Schneider M, Handgriff L, Hermann M Abstract BACKGROUND: The objective of this study was to determine if the laryngeal twitch response, when compared to neuromonitoring, can predict postoperative vocal cord function...
Fri Mar 20, 2020 12:48
Related ArticlesLaryngeal gout mimicking chondrosarcoma with concurrent longus colli tendinitis. BMJ Case Rep. 2019 Oct 25;12(10): Authors: Lee SYC, Gan YJ, Goh JPN, Ho YH, Lim MY Abstract A 42-year-old man with multiple comorbidities, including gout, presented to the emergency department with severe odynophagia for 4 days with intermittent dysphagia for 1-2 months. A CT scan of the neck showed right longus colli tendinitis and partially calcified excrescences...
Fri Mar 20, 2020 12:48
Related ArticlesTransendoscopic correction of epiglottic entrapment with a silicone-covered laser guide and diode laser in 29 horses. Vet Surg. 2020 Jan;49(1):131-137 Authors: Beste KJ, Ortved KF, Rossignol F, Ducharme NG Abstract OBJECTIVE: To describe the use of a silicone-covered laser guide and diode laser for surgical correction of epiglottic entrapment and report postoperative outcomes in horses with epiglottic entrapment. STUDY DESIGN:...
Fri Mar 20, 2020 12:48
Related ArticlesExamination of laryngeal function of healthy dogs by using sedation protocols with dexmedetomidine. Vet Surg. 2020 Jan;49(1):124-130 Authors: DeGroot WD, Tobias KM, Browning DC, Zhu X Abstract OBJECTIVE: To determine the ability to evaluate laryngeal function under sedation with dexmedetomidine alone or in combination with opioids. STUDY DESIGN: Randomized, crossover, blinded study. ANIMALS: Eight adult research hounds...
Fri Mar 20, 2020 12:48
Related ArticlesRacing performance of National Hunt thoroughbred racehorses after treatment of palatal dysfunction with a laryngeal tie-forward procedure and thermocautery of the soft palate with or without aryepiglottic folds resection. Vet Surg. 2020 Jan;49(1):114-123 Authors: Koskinen MJ, Virtala AK, McNally T Abstract OBJECTIVE: To assess racing performance of National Hunt thoroughbred (NH) racehorses with a definite diagnosis of palatal dysfunction...
Fri Mar 20, 2020 12:48
Related ArticlesSubglottic squamous cell carcinoma in Denmark 1971-2015 - a national population-based cohort study from DAHANCA, the Danish Head and Neck Cancer group. Acta Oncol. 2019 Oct;58(10):1509-1513 Authors: Hill-Madsen L, Kristensen CA, Andersen E, Johansen J, Andersen LJ, Primdahl H, Overgaard J, Lyhne NM PMID: 31364888 [PubMed - indexed for MEDLINE]
Fri Mar 20, 2020 12:48
Related ArticlesDomain specific cognitive impairment in Parkinson's patients with mild cognitive impairment. J Clin Neurosci. 2020 Mar 16;: Authors: Chaudhary S, Kumaran SS, Kaloiya GS, Goyal V, Sagar R, Kalaivani M, Jaganathan NR, Mehta N, Srivastava A Abstract Mild cognitive impairment (MCI) affects nearly 20-50% patients with Parkinson's disease (PD). It may be the prodromal stage of dementia and impacts quality of life of the patient and caregiver....
Sat Mar 21, 2020 13:19
Related ArticlesGermline epigenetic inheritance: Challenges and opportunities for linking human paternal experience with offspring biology and health. Evol Anthropol. 2020 Mar 20;: Authors: Ryan CP, Kuzawa CW Abstract Recently, novel experimental approaches and molecular techniques have demonstrated that a male's experiences can be transmitted through his germline via epigenetic processes. These findings suggest that paternal exposures influence phenotypic...
Sat Mar 21, 2020 13:18
Related ArticlesErratum. Evol Anthropol. 2020 Mar 19;: Authors: PMID: 32191369 [PubMed - as supplied by publisher]
Fri Mar 20, 2020 16:56
Related ArticlesRecent Advances in the Development of Biomarkers and Chemoradiotherapeutic Approaches for Nasopharyngeal Carcinoma. Am Soc Clin Oncol Educ Book. 2020 Mar;40:1-11 Authors: Ma BBY, Chen YP, Hui EP, Liu X, Chan AKC, Chan ATC, Ma J Abstract Epstein-Barr virus (EBV) associated nasopharyngeal carcinoma (NPC) is endemic in Southern China, and the prognosis of this cancer has improved in part due to advances in radiotherapy (RT) techniques, broadened...
Sat Mar 21, 2020 13:15
Related ArticlesNeurocap Use for the Treatment of Iatrogenic Neuropathic Pain: Preliminary Operative Results in 3 Patients. Ear Nose Throat J. 2020 Mar 19;:145561320912048 Authors: de Ru JA, Thomeer HGXM, Tijink BM, van Doormaal TPC Abstract Painful neuromas are a devastating condition that is notoriously difficult to treat. The large number of techniques that have been attempted suggest that no one technique is superior. Neuromas often occur in...
Sat Mar 21, 2020 13:10
Related ArticlesThe Role of Mastoidectomy in Draining Ventilation Tubes. Ear Nose Throat J. 2020 Mar 19;:145561320913350 Authors: Jones JW, Archbold R, Hillman TA, Chen DA Abstract OBJECTIVES: To discuss the indication for performing a mastoidectomy with catheter placement in patients with chronic tympanostomy tube otorrhea. METHODS: The Medical Literature Analysis and Retrieval System Online was searched via PubMed for relevant articles...
Fri Mar 20, 2020 14:38
Related ArticlesThe History of Myringotomy and Grommets. Ear Nose Throat J. 2020 Mar 19;:145561320914438 Authors: Rimmer J, Giddings CE, Weir N Abstract The first recorded myringotomy was in 1649. Astley Cooper presented 2 papers to the Royal Society in 1801, based on his observations that myringotomy could improve hearing. Widespread inappropriate use of the procedure followed, with no benefit to patients; this led to it falling from favor for many...
Fri Mar 20, 2020 14:38
Related ArticlesIntegrating complementary medicine in the perioperative period: a simple, opioid-sparing addition to your multimodal analgesia strategy? Reg Anesth Pain Med. 2020 Mar 18;: Authors: Kelleher DC, Kirksey MA, Wu CL, Cheng SI Abstract The current US opioid health-related crisis underscores the importance for perioperative physicians to optimize various approaches to pain management. Multimodal techniques and enhanced recovery after surgery...
Sat Mar 21, 2020 12:55
Related ArticlesLong-term incidence of chronic postsurgical pain after thoracic surgery for lung cancer: a 10-year single-center retrospective study. Reg Anesth Pain Med. 2020 Mar 17;: Authors: Yoon S, Hong WP, Joo H, Kim H, Park S, Bahk JH, Lee HJ Abstract BACKGROUND: The long-term incidence of chronic postsurgical pain (CPSP) after thoracic surgery has not yet been reported. METHODS: We retrospectively reviewed the electronic medical...
Fri Mar 20, 2020 12:25
Related ArticlesA novel non-agonist c-Met antibody drug conjugate with superior potency over a c-Met tyrosine kinase inhibitor in c-Met amplified and non-amplified cancers. Cancer Biol Ther. 2020 Mar 19;:1-11 Authors: Fujita R, Blot V, Wong E, Stewart C, Lieuw V, Richardson R, Banah A, Villicana J, Timmer A, Coronella J, Newman R, Gymnopoulos M Abstract c-Met is a well-characterized oncogene that is associated with poor prognosis in many solid tumor...
Sat Mar 21, 2020 12:53
Related ArticlesRegulatory Role of Hexokinase 2 in Modulating Head and Neck Tumorigenesis. Front Oncol. 2020;10:176 Authors: Li WC, Huang CH, Hsieh YT, Chen TY, Cheng LH, Chen CY, Liu CJ, Chen HM, Huang CL, Lo JF, Chang KW Abstract To support great demand of cell growth, cancer cells preferentially obtain energy and biomacromolecules by glycolysis over mitochondrial oxidative phosphorylation (OxPhos). Among all glycolytic enzymes, hexokinase (HK), a...
Sat Mar 21, 2020 12:51
Related ArticlesIs an Ultrasonic and Bipolar Integrated Energy Device More Useful Than a Conventional Electric Device in Head and Neck Free Flap Reconstruction? A Prospective Comparison. J Oral Maxillofac Surg. 2020 Feb 21;: Authors: Chang JW, Na G, Shin SH, Kim YS, Koo BS, Ahn SH, Chang Choi E, Kim WS Abstract PURPOSE: Thunderbeat (TB) is an integrated energy device incorporating ultrasonic and bipolar technology that provides rapid cut and precision...
Sat Mar 21, 2020 12:51
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