Κυριακή 22 Μαρτίου 2020


Reproductive tract extracellular vesicles are sufficient to transmit intergenerational stress and program neurodevelopment
Nature Communications - current - nature.com science feeds
Fri Mar 20, 2020 02:00
Degree and site of chromosomal instability define its oncogenic potential
Nature Communications - current - nature.com science feeds
Fri Mar 20, 2020 02:00
Machine learning for cluster analysis of localization microscopy data
Nature Communications - current - nature.com science feeds
Fri Mar 20, 2020 02:00
500 microkelvin nanoelectronics
Nature Communications - current - nature.com science feeds
Fri Mar 20, 2020 02:00
OXPHOS remodeling in high-grade prostate cancer involves mtDNA mutations and increased succinate oxidation
Nature Communications - current - nature.com science feeds
Fri Mar 20, 2020 02:00
Electricity-powered artificial root nodule
Nature Communications - current - nature.com science feeds
Fri Mar 20, 2020 02:00
NELL2-Robo3 complex structure reveals mechanisms of receptor activation for axon guidance
Nature Communications - current - nature.com science feeds
Fri Mar 20, 2020 02:00
Study of Toll-like receptor 3 gene polymorphism as a novel risk factor for HCV-related Hepatocellular Carcinoma in Egypt.
Related ArticlesStudy of Toll-like receptor 3 gene polymorphism as a novel risk factor for HCV-related Hepatocellular Carcinoma in Egypt. Curr Cancer Drug Targets. 2020 Mar 18;: Authors: El-Sharawy S, Negm OE, Abd-Elsalam S, El-Sorogy HA, Shehata MAH Abstract BACKGROUND & AIMS: Hepatocellular carcinoma (HCC) is a highly aggressive cancer with few treatment options. Toll-like receptor 3 (TLR3) plays a key role in innate immunity and may affect the...
Current Cancer Drug Targets,http://goo.gl/gS0SK0
Fri Mar 20, 2020 13:53
Epidural Fibrin Sealant Injection for the Management of Cerebrospinal Fluid Leak Following Dural Puncture in Children.
Related ArticlesEpidural Fibrin Sealant Injection for the Management of Cerebrospinal Fluid Leak Following Dural Puncture in Children. Cureus. 2020 Feb 10;12(2):e6940 Authors: Armstrong SA, Nguyen HTN, Rebsamen SL, Iskandar B, Stadler JA Abstract Cerebrospinal fluid (CSF) leak, intracranial hypotension, and postdural puncture headaches are common following dural punctures. Management usually consists of conservative treatments with medications (e.g....
leak of cerebrospinal fluid
Fri Mar 20, 2020 13:43
The impact of the effective dose to immune cells on lymphopenia and survival of esophageal cancer after chemoradiotherapy
Publication date: May 2020Source: Radiotherapy and Oncology, Volume 146Author(s): Cai Xu, Jian-Yue Jin, Ming Zhang, Amy Liu, Jun Wang, Radhe Mohan, Fengming (Spring) Kong, Steven H. Lin
Radiotherapy and Oncology
Fri Mar 20, 2020 13:34
Comparison of clinical outcomes between passive scattering versus pencil-beam scanning proton beam therapy for hepatocellular carcinoma
Publication date: May 2020Source: Radiotherapy and Oncology, Volume 146Author(s): Gyu Sang Yoo, Jeong Il Yu, Sungkoo Cho, Sang Hoon Jung, Youngyih Han, Seyjoon Park, Yoonjin Oh, Boram Lee, Hee Chul Park, Do Hoon Lim, Moon Seok Choi, Hojeong Won
Radiotherapy and Oncology
Fri Mar 20, 2020 13:34
3D dosimetric verification of unity MR-linac treatments by portal dosimetry
Publication date: May 2020Source: Radiotherapy and Oncology, Volume 146Author(s): Iban Torres-Xirau, Igor Olaciregui-Ruiz, Jochem Kaas, Marlies E. Nowee, Uulke A. van der Heide, Anton Mans
Radiotherapy and Oncology
Fri Mar 20, 2020 13:34
Acute radiation-induced skin toxicity in hypofractionated vs. conventional whole-breast irradiation: An objective, randomized multicenter assessment using spectrophotometry
Publication date: May 2020Source: Radiotherapy and Oncology, Volume 146Author(s): Leonard Christopher Schmeel, David Koch, Frederic Carsten Schmeel, Fred Röhner, Felix Schoroth, Bettina Maja Bücheler, Birgit Mahlmann, Christina Leitzen, Heinrich Schüller, Sabine Tschirner, Arne Fuhrmann, Martina Heimann, Dilini Brüser, Alina-Valik Abramian, Thomas Müdder, Stephan Garbe, Susanne Vornholt, Hans Heinz Schild, Brigitta Gertrud Baumert, Timo Martin Wilhelm-Buchstab
Radiotherapy and Oncology
Fri Mar 20, 2020 13:34
The carnivorous digestive system and bamboo diet of giant pandas may shape their low gut bacterial diversity.
Related ArticlesThe carnivorous digestive system and bamboo diet of giant pandas may shape their low gut bacterial diversity. Conserv Physiol. 2020;8(1):coz104 Authors: Guo W, Chen Y, Wang C, Ning R, Zeng B, Tang J, Li C, Zhang M, Li Y, Ni Q, Ni X, Zhang H, Li D, Zhao J, Li Y Abstract The gut microbiota diversity of eight panda cubs was assessed during a dietary switch.Gut microbiota diversity of panda cubs significantly decreased after bamboo consumption.Carnivorous...
pubmed: "conserv physiol"[jo...
Fri Mar 20, 2020 13:30
Non‐invasive multimodal imaging by integrating optical coherence tomography with autofluorescence imaging for dental applications
Abstract We report the development of an integrated multi‐functional imaging system capable of providing anatomical (optical coherence tomography, OCT), functional (OCT angiography, OCTA) and molecular imaging (light‐induced autofluorescence, LIAF) for in vivo dental applications. Blue excitation light (405 nm) was used for LIAF imaging, while the OCT was powered by a 1310 nm swept laser source. A red‐green‐blue (RGB) digital camera, with a 450 nm cut‐on broad‐band optical filter, was used for...
Journal of Biophotonics
Fri Mar 20, 2020 13:11
Successful Control of a Co-Infection Caused by Candida albicans and Pseudomonas aeruginosa in Keratitis.
Related ArticlesSuccessful Control of a Co-Infection Caused by Candida albicans and Pseudomonas aeruginosa in Keratitis. Infect Disord Drug Targets. 2020 Mar 18;: Authors: Paul D, Saha S, Singh N, Sengupta J, Mandal SM Abstract INTRODUCTION: Nowadays, co-infection by interspecific organisms is major threat in infection control. To identify the effective combination of drugs to control the keratitis caused by Candida albicans with Pseudomonas aeruginosa...
Infectious disorders drug targets,http://goo.gl/XqkpND
Fri Mar 20, 2020 13:02
Simultaneous detection of drug-resistant mutations in Mycobacterium tuberculosis and determining their role through in silico docking.
Related ArticlesSimultaneous detection of drug-resistant mutations in Mycobacterium tuberculosis and determining their role through in silico docking. Infect Disord Drug Targets. 2020 Mar 18;: Authors: Nachappa S, Neelambike S, Sarikhani A, Ramachandra N Abstract A molecular method for diagnosis of drug-resistant Tuberculosis is Multiplex allele-specific PCR (MAS-PCR), which is more time-efficient. Also, understanding the role of mutations when translated...
Infectious disorders drug targets,http://goo.gl/XqkpND
Fri Mar 20, 2020 13:02
Bacteriological Profile and Antibiotic Resistance in patients with Urinary tract infection in Tertiary care teaching Hospital in western Rajasthan India.
Related ArticlesBacteriological Profile and Antibiotic Resistance in patients with Urinary tract infection in Tertiary care teaching Hospital in western Rajasthan India. Infect Disord Drug Targets. 2020 Mar 18;: Authors: Meena M, Kishoria N, Meena DS, Sonwal VS Abstract BACKGROUND: UTI is one of the commonest bacterial infection with significant economic burden on the health care system in developing countries like India. Rising antibiotic resistance...
Infectious disorders drug targets,http://goo.gl/XqkpND
Fri Mar 20, 2020 13:02
Predictable tones elicit stimulus-specific suppression of evoked activity in auditory cortex.
Related ArticlesPredictable tones elicit stimulus-specific suppression of evoked activity in auditory cortex. Neuroimage. 2019 10 15;200:242-249 Authors: Han B, Mostert P, de Lange FP Abstract The auditory cortex is sensitive to many forms of acoustic regularity, resulting in suppressed neural activity for expected auditory events. It is unclear whether this activity reduction for expected events is the result of suppression of neurons that are tuned...
cortical auditory
Fri Mar 20, 2020 12:53
Decoding of selective attention to continuous speech from the human auditory brainstem response.
Related ArticlesDecoding of selective attention to continuous speech from the human auditory brainstem response. Neuroimage. 2019 10 15;200:1-11 Authors: Etard O, Kegler M, Braiman C, Forte AE, Reichenbach T Abstract Humans are highly skilled at analysing complex acoustic scenes. The segregation of different acoustic streams and the formation of corresponding neural representations is mostly attributed to the auditory cortex. Decoding of selective...
cortical auditory
Fri Mar 20, 2020 12:53
Artificial Intelligence Distinguishes COVID-19 from Community Acquired Pneumonia on Chest CT.
Related ArticlesArtificial Intelligence Distinguishes COVID-19 from Community Acquired Pneumonia on Chest CT. Radiology. 2020 Mar 19;:200905 Authors: Li L, Qin L, Xu Z, Yin Y, Wang X, Kong B, Bai J, Lu Y, Fang Z, Song Q, Cao K, Liu D, Wang G, Xu Q, Fang X, Zhang S, Xia J, Xia J Abstract Background Coronavirus disease has widely spread all over the world since the beginning of 2020. It is desirable to develop automatic and accurate detection of COVID-19...
Radiology
Fri Mar 20, 2020 14:54
Temporal Changes of CT Findings in 90 Patients with COVID-19 Pneumonia: A Longitudinal Study.
Related ArticlesTemporal Changes of CT Findings in 90 Patients with COVID-19 Pneumonia: A Longitudinal Study. Radiology. 2020 Mar 19;:200843 Authors: Wang Y, Dong C, Hu Y, Li C, Ren Q, Zhang X, Shi H, Zhou M Abstract Background CT may play a central role in the diagnosis and management of COVID-19 pneumonia. Purpose To perform a longitudinal study to analyze the serial CT findings over time in patients with COVID-19 pneumonia. Materials and Methods...
Radiology
Fri Mar 20, 2020 14:54
Identification of key gene modules and hub genes of human mantle cell lymphoma by coexpression network analysis
Purpose Mantle cell lymphoma (MCL) is a rare and aggressive subtype of non-Hodgkin lymphoma that is incurable with standard therapies. The use of gene expression analysis has been of interest, recently, to detect biomarkers for cancer. There is a great need for systemic coexpression network analysis of MCL and this study aims to establish a gene coexpression network to forecast key genes related to the pathogenesis and prognosis of MCL. Methods The microarray dataset GSE93291 was downloaded...
PeerJ Computer Science
Fri Mar 20, 2020 02:00
Substrate rugosity and temperature matters: patterns of benthic diversity at tropical intertidal reefs in the SW Atlantic
Modeling and forecasting ocean ecosystems in a changing world will require advances in observational efforts to monitor marine biodiversity. One of the observational challenges in coastal reef ecosystems is to quantify benthic and climate interactions which are key to community dynamics across habitats. Habitat complexity (i.e., substrate rugosity) on intertidal reefs can be an important variable explaining benthic diversity and taxa composition, but the association between substrate and seasonal...
PeerJ Computer Science
Fri Mar 20, 2020 02:00
RNA binding proteins involved in regulation of protein synthesis to initiate biogenesis of secondary tumor in hepatocellular carcinoma in mice
Background The tumor microenvironment (TM) in close contact with cancer cells is highly related to tumor growth and cancer metastasis. This study is to explore the biogenesis mechanism of a secondary hepatocellular carcinoma (HCC) based on the function of RNA binding proteins (RBPs)-encoding genes in the physiological microenvironment (PM). Methods The healthy and HCC mice were used to isolate the PM, pre-tumor microenvironment...
PeerJ Computer Science
Fri Mar 20, 2020 02:00
Long-term impact of a 4-day feed restriction at the protozoea stage on metabolic gene expressions of whiteleg shrimp (Litopenaeus vannamei)
Based on the “nutritional programming” concept, we evaluated the long-term effects of an early four-day caloric restriction (40% reduction in feed allowance compared to a normal feeding level) at the protozoea stage in whiteleg shrimp. We analyzed long-term programming of shrimp by studying metabolism at the molecular level, through RT-qPCR of key biomarkers (involved in intermediary metabolism and digestion). The mRNA levels (extracted from the whole body) were analyzed after the stimulus and after...
PeerJ Computer Science
Fri Mar 20, 2020 02:00
Comparative functional genomic analysis of Alzheimer’s affected and naturally aging brains
Background Alzheimer’s disease (AD) is a prevalent progressive neurodegenerative human disease whose cause remains unclear. Numerous initially highly hopeful anti-AD drugs based on the amyloid-β (Aβ) hypothesis of AD have failed recent late-phase tests. Natural aging (AG) is a high-risk factor for AD. Here, we aim to gain insights in AD that may lead to its novel therapeutic treatment through conducting meta-analyses of gene expression microarray data from AG and AD-affected brain....
PeerJ Computer Science
Fri Mar 20, 2020 02:00
The combined effects of temperature and aromatase inhibitor on metamorphosis, growth, locomotion, and sex ratio of tiger frog (Hoplobatrachus rugulosus) tadpoles
Background The tiger frog (Hoplobatrachus rugulosus) is widely raised by many farms in southern region of China as an economically edible frog. The growth, development, and sexual differentiation of amphibians are influenced by temperature and steroid hormone level. However, the problem of hormone residues is caused by the addition of exogenous hormones in frog breeding, it is worth considering whether non-sterol aromatase inhibitors can be used instead of hormones. Methods In our study,...
PeerJ Computer Science
Fri Mar 20, 2020 02:00
Icariin affects cell cycle progression and proliferation of human retinal pigment epithelial cells via enhancing expression of H19
Background Aberrant proliferation of retinal pigment epithelial (RPE) cells under pathologic condition results in the occurrence of proliferative vitreoretinopathy (PVR). Icariin (ICA)-a flavonol glucoside-has been shown to inhibit proliferation of many cell types, but the effect on RPE cells is unknown. This study aimed to clarify the inhibitory effects of ICA on RPE cells against platelet-derived growth factor (PDGF)-BB-induced cell proliferation, and discuss the regulatory function of H19 in...
PeerJ Computer Science
Fri Mar 20, 2020 02:00
Efficacy and safety of abiraterone acetate plus prednisone in Japanese patients with newly diagnosed, metastatic hormone-naive prostate cancer: final subgroup analysis of LATITUDE, a randomized, double-blind, placebo-controlled, phase 3 study.
Related ArticlesEfficacy and safety of abiraterone acetate plus prednisone in Japanese patients with newly diagnosed, metastatic hormone-naive prostate cancer: final subgroup analysis of LATITUDE, a randomized, double-blind, placebo-controlled, phase 3 study. Jpn J Clin Oncol. 2020 Mar 18;: Authors: Suzuki H, Shin T, Fukasawa S, Hashine K, Kitani S, Ohtake N, Shibayama K, Tran N, Mundle S, Fizazi K, Matsubara N Abstract BACKGROUND: LATITUDE was a randomized,...
pubmed: "jpn j clin oncol"[j...
Fri Mar 20, 2020 12:00
Artificial intelligence in glioma imaging: Challenges and advances.
Related ArticlesArtificial intelligence in glioma imaging: Challenges and advances. J Neural Eng. 2020 Mar 19;: Authors: Jin W, Fatehi M, Abhishek K, Mallya M, Toyota B, Hamarneh G Abstract Primary brain tumors including gliomas continue to pose significant management challenges to clinicians. While the presentation, the pathology, and the clinical course of these lesions are variable, the initial investigations are usually similar. Patients who are...
J Neural Eng
Fri Mar 20, 2020 13:58
A complex-valued functional brain connectivity descriptor amenable to Riemannian geometry.
Related ArticlesA complex-valued functional brain connectivity descriptor amenable to Riemannian geometry. J Neural Eng. 2020 Mar 19;: Authors: Kalaganis F, Laskaris N, Chatzilari E, Adamos DA, Nikolopoulos S, Kompatsiaris Y Abstract OBJECTIVE: We introduce a novel, phase-based, functional connectivity descriptor that encapsulates not only the synchronization strength between distinct brain regions, but also the time-lag between the involved neural oscillations....
J Neural Eng
Fri Mar 20, 2020 13:58
Magnetoencephalography resting state connectivity patterns as indicatives of surgical outcome in epilepsy patients.
Related ArticlesMagnetoencephalography resting state connectivity patterns as indicatives of surgical outcome in epilepsy patients. J Neural Eng. 2020 Mar 18;: Authors: Aydin Ü, Pellegrino G, Bin Ka'b Ali O, Abdallah C, Dubeau F, Lina JM, Kobayashi E, Grova C Abstract OBJECTIVE: Focal epilepsy is a disorder affecting several brain networks; however, epilepsy surgery usually targets a restricted region, the so-called epileptic focus. There is a growing...
J Neural Eng
Fri Mar 20, 2020 13:58
Neurovisceral regulatory circuits of affective resilience in youth
Abstract The Neurovisceral Integration Model (NIM) is one of the most influential psychophysiological models addressing the interplay between the autonomic (ANS) and central nervous system (CNS). In their groundbreaking conceptual work, integrating autonomic, attentional, and affective systems into a functional and structural network, Thayer & Lane laid the foundation for empirical research in the past two decades. The present paper provides a principal outline aiming to reflect and further...
Psychophysiology
Fri Mar 20, 2020 11:49
Extramedullary multiple myeloma involving the liver and periportal lymph node, diagnosed by EUS‐FNA in a patient with cirrhosis
Abstract Extramedullary multiple myeloma (EMM) involving the liver as a focal space‐occupying lesion is very rare, especially in the patients with cirrhosis. Here, we report a case of EMM in the liver and periportal lymph node, diagnosed by endoscopic ultrasound guided‐fine‐needle aspiration (EUS‐FNA). A 57‐year‐old male patient, with history of cirrhosis, presented with abdominal pain and pancytopenia. The abdominal magnetic resonance imaging (MRI) demonstrated a 6.5 cm left hepatic mass with...
Diagnostic Cytopathology
Fri Mar 20, 2020 11:09
Bizarre benign cells in peri‐rectal endoscopic ultrasound‐guided fine‐needle aspiration due to seminal vesicle sampling
Diagnostic Cytopathology
Fri Mar 20, 2020 11:09
The evolution of pair‐living, sexual monogamy, and cooperative infant care: Insights from research on wild owl monkeys, titis, sakis, and tamarins
Abstract “Monogamy” and pair bonding have long been of interest to anthropologists and primatologists. Their study contributes to our knowledge of human evolutionary biology and social evolution without the cultural trappings associated with studying human societies directly. Here, we first provide an overview of theoretical considerations, followed by an evaluation of recent comparative studies of the evolution of “social monogamy”; we are left with serious doubts about the conclusions of these...
American Journal of Physical Anthropology
Fri Mar 20, 2020 10:22
Obesity and type 2 diabetes: understanding the role of ethnicity
Journal of Internal Medicine
Fri Mar 20, 2020 10:22
Multiple concurrent complications of Roux-en-Y gastric bypass with MiniMizer gastric ring—alimentary limb intussusception through slipped ring into pouch, with remnant stomach internal herniation†
AbstractRoux-en-Y gastric bypass (RYGB) is the second most common bariatric procedure performed in Australia, second to sleeve gastrectomy. Banding of pouches and anastomoses, via silastic bands or MiniMizer rings, have been used to assist in improving restriction. Though banded gastric bypasses are effective in weight loss, band migration, whether it be slippage or erosion, occurs in up to 7% of banded bariatric procedures. Jejunal intussusception and internal herniation are both individually known...
Journal of Surgical Case Reports - current issue
Fri Mar 20, 2020 02:00

Which is Better for Management of Tympanic Membrane Perforation Temporalis Fascia or Fascia Lata Graft?
Abstract A good graft material is the one which is easily available and harvestable, tough and is easy to be handling and survival is good. Both temporalis fascia and fascia lata graft satisfy all these criteria. Keeping all these factors in mind, the comparative study of temporalis fascia and fascia lata graft in tympanoplasty is undertaken. All the patient reporting to ENT OPD with tympanic membrane perforation who are fit for surgery were advised tympanoplasty or tympanoplasty...
Otolaryngology Indian
Fri Mar 20, 2020 02:00
Correction to: Relationship between P1NP, a biochemical marker of bone turnover, and bone mineral density in patients transitioned from alendronate to romosozumab or teriparatide: a post hoc analysis of the STRUCTURE trial
In the original publication of the article, the last row of Table 1 was published incorrectly as “Serum P1NP (μmol/L), median (IQR)b : Romosozumab, 25 (18, 34); Teriparatide, 25 (20, 33)”. The correct row should be read as “Serum P1NP (μg/L), median (IQR)b : Romosozumab, 25 (18, 34); Teriparatide, 25 (20, 33)”.
Journal of Bone and Mineral Metabolism
Fri Mar 20, 2020 02:00
Double stenting in T configuration with safety micro-guidewire technique in a complex middle cerebral artery stenosis
Abstract Intracranial arterial stenosis is a frequently misdiagnosed cause of ischemic stroke, associated with high rates of recurrence under medical therapy alone. Endovascular intracranial angioplasty and stenting has increasingly been used worldwide for treatment of symptomatic intracranial stenoses, despite controversial results of the first randomized trials. Lesion morphology and etiology must be considered during endovascular treatment planning. Complex morphologies can...
Neuroradiology
Fri Mar 20, 2020 02:00
High-resolution compressed-sensing time-of-flight MRA in a case of acute ICA/MCA dissection
Abstract Purpose Acute, isolated intracranial dissection (ICD) represents a rare and challenging cause of acute stroke. DSA is considered to be the gold standard imaging modality in patients with ICD. The role of novel, high-resolution (HR) compressed-sensing (CS) time-of-flight (TOF) MRA techniques in ICDs is unclear. Methods A 22-year-old male patient...
Neuroradiology
Fri Mar 20, 2020 02:00

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