Κυριακή 22 Μαρτίου 2020


Hemophagocytic lymphohistiocytosis with advanced malignant melanoma accompanied by ipilimumab and nivolumab: a case report and literature review
Wiley: Dermatologic Therapy: Table of Contents
Fri Mar 20, 2020 13:20
Lime partially suspends its scooter service due to coronavirus
The suspension was initiated to “help people stay put and stay safe,” Lime’s CEO said. (Lime/)This story originally featured on Cycle Volta.Lime announced Tuesday that it’s suspending its scooter sharing service in more than 21 US states, Canada, and select countries in Europe and the Middle East to encourage the public to stay indoors amid the COVID-19 virus outbreak.“The COVID-19 virus is an unprecedented challenge facing cities and communities around the world. Like you, we are worried about the...
Popular Science
Sat Mar 21, 2020 11:00
National monuments help local economies
An aerial view of the Valley of the Gods, an area that used to be in the Bears Ears monument, but was cut out in 2017 (Bureau of Land Management/)When President Trump declared plans to downsize Bears Ears and Grand Staircase-Escalante national monuments in 2017, supporters of the decision claimed that the monuments could harm the industries that nearby communities relied on. After Bear Ears’ original designation, residents of adjacent counties had worried about the impact on mining and ranching.However,...
Popular Science
Fri Mar 20, 2020 22:30
Watch this gorgeous timelapse of the making of our ‘chicken and egg’ cover
Popular Science Spring 2020 issue cover (PopSci/)What came first: the chicken or the egg? When it comes to making our cover for the Spring 2020 issue about “Origins,” at least, the egg wins. Specifically, 15 wooden nesting dolls ranging in size from a tiny thimble to a Starbucks venti latte.Robin Finlay, the prop-styling half of photography duo The Voorhes, sanded and painted the pieces again and again until they’d appear as smooth as the real deal in front of the camera. Then, using a special laser,...
Popular Science
Fri Mar 20, 2020 21:30
How to stop touching your face
People touch their faces more when they are anxious, embarrassed or stressed, but also when they aren’t feeling anything at all. (Pexels/)Stephen D. Benning is an Assistant Professor of Psychology, University of Nevada, Las Vegas. Brian Labus is an Assistant Professor of Epidemiology and Biostatistics, University of Nevada, Las Vegas. Kimberly A. Barchard is a Professor of Quantitative Psychology, University of Nevada, Las Vegas. This story originally featured on The Conversation.Public health officials...
Popular Science
Fri Mar 20, 2020 20:30
This new 1.2-ton torpedo can hit a target 31 miles away
The F21 torpedo. (France's Naval Group/)The heavyweight torpedoes launched by submarines are secret, unseen, mysterious. Their universe: the dark silence of deep oceans. Their purpose: to destroy enemy subs and surface warships. Their use: only once every 80 years or so.The weapon is more likely to sit in its launching tube for 30 or 35 years—that’s the average life-span of a heavyweight torpedo—and then be dismantled, than it is to be shot at an enemy. That makes the delivery of a brand new, designed-from-scratch,...
Popular Science
Fri Mar 20, 2020 18:00
Sturdy wheelbarrows for all your hauling needs
Make your life a lot easier. (Nagesh Badu via Unsplash/)When you think of the things that technology and advanced materials have improved upon or refined, odds are the first thing you think of is not "the wheelbarrow." If anything, you likely envision the wheelbarrow as being stubbornly and defiantly planted in an era where people had to work the land they lived on or starve to death.And yet, even the humble wheelbarrow can be tweaked or improved or streamlined. If you have some home improvement...
Popular Science
Fri Mar 20, 2020 17:16
Scientists discover two new shark species with chainsaw-like noses
Sawsharks are known for their long, flat snouts studded with teeth, which they use to slash their prey to ribbons. Researchers have found two new species of this shark in the waters off eastern Africa. (Courtesy of Simon Weigmann/)Researchers have identified two new species of shark in the waters off eastern Africa. The rare little creatures range from about three to four-and-a-half feet in length and belong to a group called sixgill sawsharks. Their discovery came as a surprise to scientists, who...
Popular Science
Fri Mar 20, 2020 22:14
The best multi-headphone power amps for studio use
So everyone can hear. (Jan Střecha via Unsplash/)We’ve all shared earbuds and used headphone splitters to share music and listen with others. In studio settings, multiple people often need to hear the same thing at the same time, and it takes more than a simple splitter adapter to get the job done. Unlike splitters, a dedicated headphone amp sends the proper amount of power to each pair of headphones, preventing distortion and overloading that can hurt your ears and damage your headphones. It also...
Popular Science
Fri Mar 20, 2020 16:02
Four high chairs that offer more than just a place to eat
Meal-friendly seating. (Tanaphong Toochinda via Unsplash/)It’s a relatively short but important period in your child’s life: the high chair years. That magical time when they can sit eye-level with the rest of the family, perched atop a throne-like chair, and proceed to launch, mash, and pour food stuff everywhere (including, sometimes, their mouths).Choosing the right high chair means making a lot of choices—plastic vs. wood, multi-function or basic—so a lot depends on your specific wants. But these...
Popular Science
Fri Mar 20, 2020 15:07
Your smartphone photos take up too much space. Here’s how to downsize them.
That photo of a gull could be a real albatross for your phone's memory space. (Darya Tryfanava/Unsplash/)Smartphone cameras have a problem: The photos they take are too good for lots of things. The 12-megapixel camera on my iPhone XS Max takes images that are between about two and five megabytes in size, depending on how complicated and colorful the shot is. That’s awesome when you want high-quality photos, but it makes sending more than one or two files a painful experience—especially if you have...
Popular Science
Fri Mar 20, 2020 15:33
Affordable digital watches for the style conscious
Easy to read and easy to wear. (Haidan via Unsplash/)While it’s advisable to be skeptical of products that push style over substance, it’s equally advisable to celebrate those that can bring both to the table. For a long time, digital watches suffered from bulky, unattractive designs—like wearing calculators on your wrist.But times have changed, and you now have more options that better suit your overall aesthetic—without skimping on functionality.What time do we invade the rebel base? (Amazon/)It’s...
Popular Science
Fri Mar 20, 2020 14:32
Bathing monkeys, squabbling birds, and more captivating Smithsonian Photo Contest finalists
Pictures capture everything that a short glance can’t, including nature’s swift pace and the commotion of our daily lives. Smithsonian magazine’s 17th annual photo contest gives photographers all over the world a chance to show off their once-in-a-lifetime snaps. See all 60 finalists and vote for your favorite Readers’ Choice photo here by March 30. Check out some of our favorites below.A fisherman works along the coastline of Vietnam’s Phú Yên province, where local families follow near-shore currents...
Popular Science
Fri Mar 20, 2020 14:00
Correction to: Three‑dimensional topography of scapular nutrient foramina
Correction to: Surgical and Radiologic Anatomy
Surgical and Radiologic Anatomy
Sat Mar 21, 2020 02:00
Issue Information
European Journal of Neuroscience
Sat Mar 21, 2020 11:02
Issue Information
European Journal of Neuroscience
Sat Mar 21, 2020 11:02
Ca 2 + release and buffering effects of synthetic hydroxyapatite following bacterial acid challenge
Abstract Background Synthetic particulate hydroxyapatite (HAP; Ca5(PO4)3(OH)) is used as ingredient in oral care products but its effects on cariogenic biofilms are not clear yet. The primary mode of action of HAP may be acting as a calcium phosphate reservoir when deposited in oral biofilms and release Ca2+ and (hydrogen) phosphate ions upon bacterial acid challenge. The aim of this in vitro study was to test this hypothesis...
Latest Results for BMC Oral Health
Sat Mar 21, 2020 02:00
Analysis of by high-throughput sequencing: Helicobacter pylori infection and salivary microbiome
Abstracts Background There have been reports of Helicobacter pylori (H. pylori) in the oral cavity and it has been suggested that the oral cavity may be a reservoir for H. pylori reflux from the stomach. High-throughput sequencing was used to assess the structure and composition of oral microbiota communities in individuals with or without confirmed H. pylori infection. ...
Latest Results for BMC Oral Health
Fri Mar 20, 2020 02:00
Announcement from the Editors
The European Gastrointestinal Motility Society
Sat Mar 21, 2020 10:46
Issue Information
The European Gastrointestinal Motility Society
Sat Mar 21, 2020 10:46
Urocortin 1: A putative excitatory neurotransmitter in the enteric nervous system
Ucn1 acts as an excitatory neurotransmitter in the ENS enhancing the cholinergic neurotransmission. Abstract Background Urocortin 1 (Ucn1), a stress‐related peptide, is a member of the corticotropin‐releasing factor (CRF) family and acts as a CRF1 receptor agonist. Ucn1 and CRF1 receptor immunoreactivity are present in the enteric nervous system (ENS), and Ucn1 elicits contraction of colonic muscle strips. Considering these findings, we have hypothesized that Ucn1 acts as an excitatory neurotransmitter...
The European Gastrointestinal Motility Society
Sat Mar 21, 2020 10:46
Cotard’s Parasomnia: Le Délire de Negation that occur during the Sleep-Wake Dissociation?
Journal of Clinical Sleep Medicine, Ahead of Print.
The American Academy of Sleep Medicine
Fri Mar 20, 2020 09:00
Symptom severity in burning mouth syndrome associates with psychological factors
Abstract Background Burning mouth syndrome (BMS) patients are psychologically distressed, but whether this associates with symptom severity is unclear. Objective To investigate the association of psychological factors with pain intensity and interference in BMS. Methods 52 women (mean age 63.1, SD 10.9) with BMS participated. Pain intensity and interference data was collected using 2‐week pain diaries. Psychological factors were evaluated using Depression scale (DEPS),...
Journal of Oral Rehabilitation
Sat Mar 21, 2020 10:33
The Impact of Orofacial Appearance on Oral Health Related Quality of Life: A Systematic Review
Abstract Esthetics in the orofacial region is important for perceived oral health and a common reason for treatment of discoloured, missing or crowded teeth. As one of the fundamental bricks of a patient's oral health, changes in the domain of orofacial esthetics resides within the Oral Health Related Quality of Life (OHRQoL) of an individual. Four main dimensions, Oral Function, Orofacial Pain, Orofacial Appearance, and Psychosocial Impact, are suggested to cover the concept of OHRQoL. The aim...
Journal of Oral Rehabilitation
Sat Mar 21, 2020 10:33
Food intake and oral health status of inpatients with dysphagia in acute care settings
Abstract Background Adequate oral status and functional assessments are important for dysphagia rehabilitation in acute care inpatient settings, especially to establish individualized oral intake. However, the association between food intake levels and oral function has not been elucidated in acute care inpatients. Objective This cross‐sectional study clarified the association between oral intake levels and the oral status/function of patients with dysphagia admitted to acute care...
Journal of Oral Rehabilitation
Sat Mar 21, 2020 10:33
Covid-19 and the Stiff Upper Lip — The Pandemic Response in the United Kingdom
New England Journal of Medicine, Ahead of Print.
Massachusetts Medical Society: New England Journal of Medicine: Table of Contents
Fri Mar 20, 2020 07:00
Adsorption of Cr(VI) in Aqueous Solution Using a Surfactant-Modified Bentonite
Clay minerals can be modified organically by a cationic surfactant resulting in materials known as organoclays. The organoclays have been used as adsorbents of most of the organic contaminants in the aqueous solution and oxyanions of the heavy metal. In this study, a Colombian bentonite was modified with hexadecyltrimethylammonium bromide to obtain an organobentonite, and its capacity to adsorb Cr(VI) oxyanions in the aqueous solution was evaluated. The effect of pH, stirring speed, adsorbent amount,...
The Scientific World Journal
Sat Mar 21, 2020 05:20
Preterm Birth and Receipt of Postpartum Contraception Among Women with Medicaid in North Carolina
Abstract Objectives To compare receipt of contraception and method effectiveness in the early postpartum period among women with and without a recent preterm birth (PTB). Methods We used data from North Carolina birth certificates linked to Medicaid claims. We assessed contraceptive claims with dates of service within 90 days of delivery among a retrospective...
Latest Results for Maternal and Child Health Journal
Sat Mar 21, 2020 02:00
Real‐word experience with Mepolizumab: Does it deliver what it has promised?
Abstract Background Randomized control trials performed in selected populations of severe eosinophilic asthmatics have shown that mepolizumab, an anti‐IL5 therapy, was able to reduce exacerbations and OCS maintenance dose and in some studies, to improve asthma control and lung function. Objective The aim of this study was to confirm the results of the RCTs in real‐life in a population of 116 severe eosinophilic asthmatics treated with mepolizumab and who were followed up at the asthma...
Clinical & Experimental Allergy
Sat Mar 21, 2020 09:57
CD16highCD62Ldim neutrophils induce nerve mediated airway hyperreactivity
Abstract Inflammatory cells, such as neutrophils, eosinophils and mast cells are found in the airways and lungs of asthmatic patients. Generally, eosinophils and mast cells have been given more attention in allergic asthma than neutrophils. Eosinophils and mast cells are known to contribute to chronic inflammation, airway obstruction and hyperresponsiveness. The neutrophils have been easy to overlook, as they are present in the lung at all times, even in non‐symptomatic asthmatic patients.
Clinical & Experimental Allergy
Sat Mar 21, 2020 09:57
Cytotoxicity and release ions of endodontic sealers incorporated with a silver and vanadium base nanomaterial
Abstract The modification of endodontic sealers with nanoparticles to confer antimicrobial activity allow greater effect, with interaction at a molecular level. The nanostructured silver vanadate decorated with silver nanoparticles (AgVO3) is a nanomaterial unprecedented in dentistry for this application. This study incorporated the AgVO3 into three endodontic sealers of different compositions and evaluate the cytotoxicity and release of compounds. The groups of commercially available...
Odontology
Sat Mar 21, 2020 02:00
Deep feature–based automatic classification of mammograms
Abstract Breast cancer has the second highest frequency of death rate among women worldwide. Early-stage prevention becomes complex due to reasons unknown. However, some typical signatures like masses and micro-calcifications upon investigating mammograms can help diagnose women better. Manual diagnosis is a hard task the radiologists carry out frequently. For their assistance, many computer-aided diagnosis (CADx) approaches have been developed. To improve upon the state of the...
Latest Results for Medical
Sat Mar 21, 2020 02:00
Acute exacerbations of chronic respiratory disease: Progress and opportunities
Chronic Respiratory Disease, Volume 17, Issue , January-December 2020.
SAGE Publications Ltd STM: Chronic Respiratory Disease: Table of Contents
Fri Mar 20, 2020 03:28
Basilar Invagination: Transoral Microsurgical Endoscopically-Controlled Odontoidectomy without Palatotomy in Extreme form of Basilar Invagination
J Neurol Surg BDOI: 10.1055/s-0040-1701216 Objective Transoral odontoidectomy in the treatment of basilar invagination is surgically challenging. Incision of the soft palate significantly increases rostral exposure of the clivus but is associated with a high incidence of speech and swallowing difficulties after surgery. We present a patient suffering from severe compression of the medulla oblongata due to an extreme form of basilar invagination treated successfully with the resection of...
Journal of Neurological Surgery Part B: Skull Base
Fri Mar 20, 2020 01:00
Navigation-Assisted Posterior Open Reduction and Internal Fixation in a C-CLAMP Fashion for an Isolated C1 Fracture
J Neurol Surg BDOI: 10.1055/s-0040-1701692C1 fractures with an intact transverse ligament are usually treated conservatively. Patients who present with a progressive diastasis of bone fragments and a progressive articular subluxation mainly attributed to progressive lengthening of the transverse ligament (TAL) fibers can be treated with a C1 “C-clamp” fusion.A 75-year-old male who sustained a motor vehicle accident was neurologically intact. A computed tomography (CT) imaging demonstrated a Jefferson's...
Journal of Neurological Surgery Part B: Skull Base
Fri Mar 20, 2020 01:00
Telelecture Educational Series in Facial Plastic and Reconstructive Surgery
Facial plast SurgDOI: 10.1055/s-0040-1708840We sought to evaluate the usefulness of a monthly telelecture educational series in facial plastic and reconstructive surgery for resident education and to identify potential areas for improvement. A monthly series of facial plastic and reconstructive surgery telelectures were hosted at our institution between 2016 and 2018. A web-based survey was sent to 13 residents and 7 invited faculty presenters. Resident survey questions included rating of presentation...
Facial Plastic Surgery
Fri Mar 20, 2020 01:00
Inhibition of oxygen-sensing prolyl hydroxylases increases lipid accumulation in human primary tubular epithelial cells without inducing ER stress.
Related ArticlesInhibition of oxygen-sensing prolyl hydroxylases increases lipid accumulation in human primary tubular epithelial cells without inducing ER stress. Cell Tissue Res. 2020 Mar 18;: Authors: Schley G, Grampp S, Goppelt-Struebe M Abstract The role of the hypoxia-inducible transcription factor (HIF) pathway in renal lipid metabolism is largely unknown. As HIF stabilizing prolyl hydroxylase (PHD) inhibitors are currently investigated in clinical...
Hypoxia-inducible factors
Sat Mar 21, 2020 06:41
Regulation of Hippo signaling and triple negative breast cancer progression by an ubiquitin ligase RNF187
Oncogenesis, Published online: 20 March 2020; doi:10.1038/s41389-020-0220-5Regulation of Hippo signaling and triple negative breast cancer progression by an ubiquitin ligase RNF187
Oncogenesis - nature.com science feeds
Fri Mar 20, 2020 02:00
Loss of copy of <i>MIR1-2</i> increases <i>CDK4</i> expression in ileal neuroendocrine tumors
Oncogenesis, Published online: 20 March 2020; doi:10.1038/s41389-020-0221-4Loss of copy of MIR1-2 increases CDK4 expression in ileal neuroendocrine tumors
Oncogenesis - nature.com science feeds
Fri Mar 20, 2020 02:00

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