Related Articles HLX affects cell cycle and proliferation in AML cells via the JAK/STAT signaling pathway. Oncol Lett. 2020 Aug;20(2):1888-1896 Authors: Zhu XY, Guo QY, Zhu M, Chen BG, Wang LY, Zhang DQ, Zhang L, Shao YP, Luo WD Abstract Acute myelogenous leukemia (AML) is a class of malignant tumors derived from hematopoietic stem or progenitor cells. The H2.0-like homeobox gene (HLX) encodes transcription factors that function in promoting...
Thu Jul 30, 2020 14:43
Related Articles Downregulation of VRK1 reduces the expression of BANF1 and suppresses the proliferative and migratory activity of esophageal cancer cells. Oncol Lett. 2020 Aug;20(2):1163-1170 Authors: Ren Z, Geng J, Xiong C, Li X, Li Y, Li J, Liu H Abstract Esophageal squamous cell carcinoma (ESCC) is a common malignancy worldwide. The disease has a poor prognosis and a low 5-year survival rate. Therefore, it is necessary to identify new...
Thu Jul 30, 2020 14:43
Related Articles Germacrone: A potent secondary metabolite with therapeutic potential in metabolic diseases, cancer and viral infections. Curr Drug Metab. 2020 Jul 28;: Authors: Riaz A, Rasul A, Kanwal N, Hussain G, Shah MA, Sarfraz I, Ishfaq R, Batool R, Rukhsar F, Adem Ş Abstract Natural products, an infinite reserve of bioactive molecules, will continue to serve humans as an important source of therapeutic agents. Germacrone is a bioactive...
Thu Jul 30, 2020 14:43
Related Articles The Temperature-Dependent Effectiveness of Platinum-Based Drugs Mitomycin-C and 5-FU during Hyperthermic Intraperitoneal Chemotherapy (HIPEC) in Colorectal Cancer Cell Lines. Cells. 2020 Jul 25;9(8): Authors: Helderman RFCPA, Löke DR, Verhoeff J, Rodermond HM, van Bochove GGW, Boon M, van Kesteren S, Garcia Vallejo JJ, Kok HP, Tanis PJ, Franken NAP, Crezee J, Oei AL Abstract Cytoreductive surgery (CRS) followed by hyperthermic...
Thu Jul 30, 2020 14:43
Related Articles Tamoxifen and the PI3K Inhibitor: LY294002 Synergistically Induce Apoptosis and Cell Cycle Arrest in Breast Cancer MCF-7 Cells. Molecules. 2020 Jul 24;25(15): Authors: Abdallah ME, El-Readi MZ, Althubiti MA, Almaimani RA, Ismail AM, Idris S, Refaat B, Almalki WH, Babakr AT, Mukhtar MH, Abdalla AN, Idris OF Abstract Breast cancer is considered as one of the most aggressive types of cancer. Acquired therapeutic resistance...
Thu Jul 30, 2020 14:43
Related Articles Severe bullous skin eruptions on checkpoint inhibitor therapy - in most cases severe bullous lichenoid drug eruptions. J Dtsch Dermatol Ges. 2019 09;17(9):942-948 Authors: Reschke R, Mockenhaupt M, Simon JC, Ziemer M PMID: 31210413 [PubMed - indexed for MEDLINE]
Thu Jul 30, 2020 14:43
Cortical and Internal Watershed Infarcts Might Be Key Signs for Predicting Neurological Deterioration in Patients with Internal Carotid Artery Occlusion with Mild Symptoms. Cerebrovasc Dis Extra. 2020 Jul 29;10(2):76-83 Authors: Amano Y, Sano H, Fujimoto A, Kenmochi H, Sato H, Akamine S Abstract BACKGROUND: Treatment for acute ischemic stroke due to large vessel occlusion (LVO) with mild symptoms is under discussion. Although most patients...
Thu Jul 30, 2020 19:53
Methylphenidate and the Risk of New-Onset Seizures. J Clin Psychiatry. 2020 Jul 21;81(4): Authors: Andrade C Abstract Attention-deficit/hyperactivity disorder (ADHD) is usually treated with stimulant drugs such as methylphenidate (MPH). ADHD is associated with an increased risk of seizures and, in this context, concerns have been expressed that stimulant drugs, including MPH, may increase the seizure risk. However, 4 large observational studies...
Thu Jul 30, 2020 19:53
Gait-combined transcranial alternating current stimulation modulates cortical control of muscle activities during gait. Eur J Neurosci. 2020 Jul 29;: Authors: Kitatani R, Koganemaru S, Maeda A, Mikami Y, Matsuhashi M, Mima T, Yamada S Abstract Non-invasive brain stimulation has been of interest as a therapeutic tool to modulate cortical excitability. However, there is little evidence that oscillatory brain stimulation can modulate the cortical...
Thu Jul 30, 2020 19:53
Related Articles Parkinsonism: A Rare Adverse Effect of Valproic Acid. Cureus. 2020 Jun 23;12(6):e8782 Authors: Muralidharan A, Rahman J, Banerjee D, Hakim Mohammed AR, Malik BH Abstract Valproic acid (VPA) is an anti-epileptic drug (AED) used as a first-choice agent for most forms of epilepsy. It is used in the treatment of manic episodes, bipolar disorder, migraine prevention, and impulse control. Hence it is one of the most commonly prescribed...
Thu Jul 30, 2020 19:53
Related Articles Hsp90 inhibitor HSP990 in very low dose upregulates EAAT2 and exerts potent antiepileptic activity. Theranostics. 2020;10(18):8415-8429 Authors: Sha L, Chen T, Deng Y, Du T, Ma K, Zhu W, Shen Y, Xu Q Abstract Rationale: Dysfunction or reduced levels of EAAT2 have been documented in epilepsy. We previously demonstrated the antiepileptic effects of Hsp90 inhibitor 17AAG in temporal lobe epilepsy by preventing EAAT2 degradation....
Thu Jul 30, 2020 19:53
Related Articles Public Knowledge and Attitude towards Epilepsy and Its Associated Factors: Community-Based Cross-Sectional Study, Ethiopia, 2019. J Environ Public Health. 2020;2020:6801979 Authors: Wubetu AD, Admasu Basha E, Alemnew Engidaw N Abstract Background: Epilepsy is a disease of the brain defined by any of the following conditions. First, at least two unprovoked (or reflex) seizures occurring greater than 24 hours apart, and secondly,...
Thu Jul 30, 2020 19:53
Related Articles The Impact of Family Strengths Oriented Therapeutic Conversations on Parents of Children with a New Chronic Illness Diagnosis. J Fam Nurs. 2020 Jul 29;:1074840720940674 Authors: Svavarsdottir EK, Kamban SW, Konradsdottir E, Sigurdardottir AO Abstract A growing number of families with children are dealing with a new diagnosis of chronic illnesses or health problems that are demanding. Nurses are in a prime position to provide...
Thu Jul 30, 2020 19:53
Related Articles Evaluation of Risk Factors for Epilepsy in Pediatric Patients with Cerebral Palsy. Brain Sci. 2020 Jul 25;10(8): Authors: Sadowska M, Sarecka-Hujar B, Kopyta I Abstract Cerebral palsy (CP) is a set of etiologically diverse symptoms that change with the child's age. It is one of the most frequent causes of motor disability in children. CP occurs at a frequency of 1.5 to 3.0 per 1000 live-born children. CP often coexists with...
Thu Jul 30, 2020 19:53
Related Articles The importance of mental health in improving quality of life in transition-aged patients with epilepsy. Epilepsy Behav. 2020 Jul 25;112:107324 Authors: Healy SA, Fantaneanu TA, Whiting S Abstract OBJECTIVE: Adolescents with epilepsy are known to have a lower quality of life (QoL) than the typically developing adolescent population. In order to address this, treating physicians have primarily focused on obtaining seizure control....
Thu Jul 30, 2020 19:53
Related Articles The effect of simulation-based education on childhood epileptic seizure management knowledge, skills, and attitudes of nursing students. Epilepsy Behav. 2019 11;100(Pt A):106497 Authors: Kahraman A, Gümüş M, Binay Ş, Zengin D, Uzşen H, Ardahan Sevgili S, Çevik Özdemir HN, Başbakkal Z Abstract BACKGROUND: Lack of knowledge about epileptic seizure management and negative attitudes toward children with epilepsy among nursing students...
Thu Jul 30, 2020 19:53
Related Articles Psychiatric disorders as predictors of epilepsy surgery outcome. Epilepsy Behav. 2019 11;100(Pt A):106513 Authors: Novais F, Pestana LC, Loureiro S, Andrea M, Figueira ML, Pimentel J Abstract OBJECTIVES: Our aim was to determine if a history of a mental disorder predicts a worst neurological outcome for patients undergoing epilepsy surgery. METHODS: We conducted an ambispective observational study including people...
Thu Jul 30, 2020 19:53
Related Articles French neuropsychological procedure consensus in epilepsy surgery. Epilepsy Behav. 2019 11;100(Pt A):106522 Authors: Brissart H, Planton M, Bilger M, Bulteau C, Forthoffer N, Guinet V, Hennion S, Kleitz C, Laguitton V, Mirabel H, Mosca C, Pécheux N, Pradier S, Samson S, Tramoni E, Voltzenlogel V, Denos M, Boutin M Abstract INTRODUCTION: Neuropsychological assessment is an integral component of the surgical procedure in patients...
Thu Jul 30, 2020 19:53
Related Articles Positive outcome of visuospatial deficit rehabilitation in children with epilepsy using computer-based FORAMENRehab program. Epilepsy Behav. 2019 11;100(Pt A):106521 Authors: Saard M, Bachmann M, Sepp K, Pertens L, Kornet K, Reinart L, Kööp C, Kolk A Abstract Children with epilepsy often show deficits in attention and visuospatial functions. Still, very few systematically controlled evidence-based pediatric neurorehabilitation...
Thu Jul 30, 2020 19:53
Related Articles Prenatal exposure to antiepileptic drugs and early processing of emotionally relevant sounds. Epilepsy Behav. 2019 11;100(Pt A):106503 Authors: Videman M, Stjerna S, Wikström V, Nybo T, Roivainen R, Vanhatalo S, Huotilainen M, Gaily E Abstract INTRODUCTION: Prenatal exposure to antiepileptic drugs (AEDs) is associated with developmental compromises in verbal intelligence and social skills in childhood. Our aim was to evaluate...
Thu Jul 30, 2020 19:53
Related Articles Reported service needs at diagnosis of epilepsy and implications for quality of life. Epilepsy Behav. 2019 11;100(Pt A):106527 Authors: Peterson CL, Walker C, Coleman H, Shears G Abstract AIM: This paper reports on contributing factors to Quality of Life (QoL) in an Australian community sample of people with epilepsy (PWE). METHOD: Three hundred and ninety-three respondents or 29.6% of people on the Australian Epilepsy...
Thu Jul 30, 2020 19:53
Related Articles Behaviour outcomes in children with epilepsy 1 year after surgical resection of the ventromedial prefrontal cortex. Neuropsychologia. 2019 10;133:107155 Authors: Stewart E, Abel TJ, Davidson B, Smith ML Abstract Early damage to the ventromedial prefrontal cortex (VM) has been associated with impaired behavioural functioning in children without epilepsy, yet behaviour in children with epilepsy and VM lesions has not been investigated....
Thu Jul 30, 2020 19:53
Related Articles Very-High-Dose Prednisolone Before ACTH for Treatment of Infantile Spasms: Evaluation of a Standardized Protocol. Pediatr Neurol. 2019 10;99:16-22 Authors: Eliyan Y, Heesch J, Alayari A, Rajaraman RR, Sankar R, Hussain SA Abstract BACKGROUND: There is ongoing debate regarding the comparative effectiveness of adrenocorticotropic hormone and prednisolone in the treatment of infantile spasms. With a large cohort and extended follow-up,...
Thu Jul 30, 2020 19:53
Related Articles Ictal Video-Electroencephalography Findings in Bathing Seizures: Two New Cases and Review of the Literature. Pediatr Neurol. 2019 10;99:76-81 Authors: Mosquera-Gorostidi A, Azcona-Ganuza G, Yoldi-Petri ME, García de Gurtubay I, Aguilera-Albesa S Abstract INTRODUCTION: Reflex bathing seizures are described during the course of bathing in water near body temperature. These seizures differ from other epilepsies characterized by...
Thu Jul 30, 2020 19:53
Related Articles Acute Disseminated Encephalomyelitis (ADEM) and Increased Intracranial Pressure Associated With Anti-Myelin Oligodendrocyte Glycoprotein Antibodies. Pediatr Neurol. 2019 10;99:64-68 Authors: Narayan RN, Wang C, Greenberg BM Abstract BACKGROUND: Antibodies to the myelin oligodendrocyte glycoprotein (MOG) have been identified in about 40% of children with acute disseminated encephalomyelitis (ADEM). The objective of this report...
Thu Jul 30, 2020 19:53
Related Articles Vigabatrin as a Targeted Treatment of GABAB Receptor-Related Epileptic Encephalopathy. Pediatr Neurol. 2019 10;99:82-84 Authors: Chin EM, Cohen JS, Harris J PMID: 31122837 [PubMed - indexed for MEDLINE]
Thu Jul 30, 2020 19:53
Immune-related adverse events: what we've learned and where we're heading. Expert Rev Anticancer Ther. 2020 Jul 29;: Authors: Badran YR, Leet DE, Dougan M PMID: 32726153 [PubMed - as supplied by publisher]
Thu Jul 30, 2020 18:10
45 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: Future Oncology These pubmed results were generated on 2020/07/30PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Thu Jul 30, 2020 14:46
45 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: Future Oncology These pubmed results were generated on 2020/07/30PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Thu Jul 30, 2020 13:47
Related Articles Non-Invasive Assessment of Hypoxia and Neovascularization with MRI for Identification of Aggressive Breast Cancer. Cancers (Basel). 2020 Jul 24;12(8): Authors: Bennani-Baiti B, Pinker K, Zimmermann M, Helbich TH, Baltzer PA, Clauser P, Kapetas P, Bago-Horvath Z, Stadlbauer A Abstract The aim of this study was to investigate the potential of magnetic resonance imaging (MRI) for a non-invasive synergistic assessment of tumor microenvironment...
Thu Jul 30, 2020 16:32
Related Articles The clinicopathological significance of the adipophilin and fatty acid synthase expression in salivary duct carcinoma. Virchows Arch. 2020 Aug;477(2):291-299 Authors: Hirai H, Tada Y, Nakaguro M, Kawakita D, Sato Y, Shimura T, Tsukahara K, Kano S, Ozawa H, Okami K, Sato Y, Fushimi C, Shimizu A, Okamoto I, Takase S, Okada T, Sato H, Imanishi Y, Otsuka K, Watanabe Y, Sakai A, Ebisumoto K, Togashi T, Ueki Y, Ota H, Saigusa N, Takahashi H, Ando...
Thu Jul 30, 2020 16:32
Related Articles Frequency, Clinicopathologic Characteristics, and Follow-up of HER2-Positive Nonpleomorphic Invasive Lobular Carcinoma of the Breast. Am J Clin Pathol. 2020 04 15;153(5):583-592 Authors: Zhang H, Moisini I, Ajabnoor RM, Turner BM, D'aguiar M, Cai X, Gao S, Yang Q, Wang X, Schiffhauer L, Hicks DG Abstract OBJECTIVES: To investigate human epidermal growth factor receptor 2 (HER2)-positive nonpleomorphic invasive lobular carcinoma...
Thu Jul 30, 2020 16:32
Related Articles High-accuracy Automated Diagnosis of Parkinson's Disease. Curr Med Imaging. 2020;16(6):688-694 Authors: Ozsahin I, Sekeroglu B, Pwavodi PC, Mok GSP Abstract PURPOSE: Parkinson's disease (PD), which is the second most common neurodegenerative disease following Alzheimer's disease, can be diagnosed clinically when about 70% of the dopaminergic neurons are lost and symptoms are noticed. Neuroimaging methods such as single photon...
Thu Jul 30, 2020 13:43
The relationship between attachment, treatment compliance and treatment outcomes in patients with obstructive sleep apnea. J Psychosom Res. 2020 Jul 23;137:110196 Authors: Adams GC, Skomro R, Wrath AJ, Le T, McWilliams LA, Fenton ME Abstract OBJECTIVE: Obstructive sleep apnea (OSA) is a common condition with numerous health and psychological consequences. While treatment with Continuous Positive Airway Pressure (CPAP) is highly effective, it...
Thu Jul 30, 2020 13:06
Related Articles Nasal versus oronasal mask in patients under auto-adjusting continuous positive airway pressure titration: a real-life study. Eur Arch Otorhinolaryngol. 2020 Jul 28;: Authors: Duarte RLM, Mendes BA, Oliveira-E-Sá TS, Magalhães-da-Silveira FJ, Gozal D Abstract PURPOSE: Mask type (nasal versus oronasal) can affect the optimal pressure required to correct the apnea/hypopnea index (AHI) in obstructive sleep apnea (OSA) subjects...
Thu Jul 30, 2020 13:06
Related Articles Combined Surgical and Orthodontic Treatments in Children with OSA: A Systematic Review. J Clin Med. 2020 Jul 26;9(8): Authors: Templier L, Rossi C, Miguez M, Pérez JC, Curto A, Albaladejo A, Vich ML Abstract Obstructive sleep apnea (OSA) is a sleeping breathing disorder. In children, adenotonsillar hypertrophy remains the main anatomical risk factor of OSA. The aim of this study was to assess the current scientific data and...
Thu Jul 30, 2020 13:06
Related Articles A Sleep Apnea Detection System Based on a One-Dimensional Deep Convolution Neural Network Model Using Single-Lead Electrocardiogram. Sensors (Basel). 2020 Jul 26;20(15): Authors: Chang HY, Yeh CY, Lee CT, Lin CC Abstract Many works in recent years have been focused on developing a portable and less expensive system for diagnosing patients with obstructive sleep apnea (OSA), instead of using the inconvenient and expensive polysomnography...
Thu Jul 30, 2020 13:06
Related Articles SMAD4 Overexpression in Patients with Sleep Apnoea May Be Associated with Cardiometabolic Comorbidities. J Clin Med. 2020 Jul 25;9(8): Authors: Díaz-García E, Jaureguizar A, Casitas R, García-Tovar S, Sánchez-Sánchez B, Zamarrón E, López-Collazo E, García-Río F, Cubillos-Zapata C Abstract Obstructive sleep apnoea (OSA) is associated with several diseases related to metabolic and cardiovascular risk. Although the mechanisms involved...
Thu Jul 30, 2020 13:06
Related Articles Hypoglossal Nerve Stimulator Placement for Pediatric Trisomy 21 Patients with Refractory Obstructive Sleep Apnea: A Case Series. Children (Basel). 2020 Jul 24;7(8): Authors: Karlik JB, Raol N, Gilbertson L Abstract BACKGROUND: Hypoglossal nerve stimulators (HNS) are an increasingly popular form of upper airway stimulation for obstructive sleep apnea (OSA) in adults who are unable to tolerate positive pressure treatment. However,...
Thu Jul 30, 2020 13:06
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