Consolidation radiotherapy for patients with extended disease small cell lung cancer in a single tertiary institution: impact of dose and perspectives in the era of immunotherapy. Radiol Oncol. 2020 Jul 29;54(3):353-363 Authors: Stanic K, Vrankar M, But-Hadzic J Abstract Background Consolidation radiotherapy (cRT) in extended disease small cell lung cancer (ED-SCLC) showed improved 2-year overall survival in patients who responded to chemotherapy...
Thu Jul 30, 2020 13:23
Related Articles Leptomeningeal Metastases in Non-small Cell Lung Cancer: Optimal Systemic Management in NSCLC With and Without Driver Mutations. Curr Treat Options Oncol. 2020 Jul 28;21(9):72 Authors: Alexander M, Lin E, Cheng H Abstract OPINION STATEMENT: As a devastating complication of non-small cell lung cancer (NSCLC), the incidence of leptomeningeal metastasis (LM) is rising, largely due to overall longer survival of NSCLC, especially...
Thu Jul 30, 2020 13:23
Related Articles Updated Analysis of the Oncology Section of the OITE from 2007 to 2019. J Cancer Educ. 2020 Jul 28;: Authors: Hoskins T, Goyette D, Patel JN, Romanelli F, Mazzei C, Sonnylal L, Sampat R, Wittig JC Abstract The Orthopaedic In-Training Exam (OITE) is administered annually to orthopedic surgery residents to assess their medical knowledge. The authors provide a comprehensive review of the orthopedic oncology portion of the exam...
Thu Jul 30, 2020 13:23
Related Articles Novel Approaches to the Systemic Management of Uveal Melanoma. Curr Oncol Rep. 2020 Jul 28;22(10):104 Authors: Khan S, Carvajal RD Abstract PURPOSE OF REVIEW: Uveal melanoma is a distinct subtype of melanoma characterized by a unique biology and divergent response to immune therapies. In this review, we will discuss our current understanding of the pathophysiology of uveal melanoma, systemic treatment options for advanced disease,...
Thu Jul 30, 2020 13:23
Related Articles Targeted Therapies in Advanced Gastric Cancer. Curr Treat Options Oncol. 2020 Jul 28;21(9):70 Authors: Patel TH, Cecchini M Abstract OPINION STATEMENT: Despite a decreasing incidence in the USA, gastric cancer is highly prevalent worldwide. Furthermore, gastric cancer remains highly lethal with median survival of less than 1 year for metastatic disease. The backbone of therapy against metastatic gastric cancer remains cytotoxic...
Thu Jul 30, 2020 13:23
Related Articles Prognostic Gene Expression Profiling in Cutaneous Melanoma: Identifying the Knowledge Gaps and Assessing the Clinical Benefit. JAMA Dermatol. 2020 Jul 29;: Authors: Grossman D, Okwundu N, Bartlett EK, Marchetti MA, Othus M, Coit DG, Hartman RI, Leachman SA, Berry EG, Korde L, Lee SJ, Bar-Eli M, Berwick M, Bowles T, Buchbinder EI, Burton EM, Chu EY, Curiel-Lewandrowski C, Curtis JA, Daud A, Deacon DC, Ferris LK, Gershenwald JE, Grossmann KF, Hu-Lieskovan...
Thu Jul 30, 2020 13:23
Related Articles Programmed death ligand-1 expression in gastrointestinal cancer: Clinical significance and future challenges. Ann Gastroenterol Surg. 2020 Jul;4(4):369-378 Authors: Yamashita K, Iwatsuki M, Ajani JA, Baba H Abstract Cancer immunotherapy has caused a paradigm shift from conventional therapies that directly target cancer cells to innovative therapies that utilize the host immune system. In particular, programmed cell death-1 (PD-1)/programmed...
Thu Jul 30, 2020 13:23
Related Articles Dual effects of active ERK in cancer: A potential target for enhancing radiosensitivity. Oncol Lett. 2020 Aug;20(2):993-1000 Authors: Lu Y, Liu B, Liu Y, Yu X, Cheng G Abstract Ionizing radiation (IR) is an important cancer treatment approach. However, radioresistance eventually occurs, resulting in poor outcomes in patients with cancer. Radioresistance is associated with multiple signaling pathways, particularly pro-survival...
Thu Jul 30, 2020 13:23
Related Articles A Roadmap for conducting psychosocial research in epidemiological studies: perspectives of cohort study principal investigators. BMJ Open. 2020 Jul 28;10(7):e037235 Authors: Argentieri MA, Seddighzadeh B, Noveroske Philbrick S, Balboni T, Shields A Abstract BACKGROUND: Psychosocial adversity disproportionately affects racial/ethnic and socioeconomic minorities in the USA, and therefore understanding the mechanisms through which...
Thu Jul 30, 2020 13:23
Related Articles Conversations and Misconceptions About Chemotherapy in Arabic Tweets: Content Analysis. J Med Internet Res. 2020 Jul 29;22(7):e13979 Authors: Alghamdi A, Abumelha K, Allarakia J, Al-Shehri A Abstract BACKGROUND: Although chemotherapy was first introduced for the treatment of cancer more than 60 years ago, the public understanding and acceptance of chemotherapy is still debatable. To the best of our knowledge, no study has assessed...
Thu Jul 30, 2020 13:23
Related Articles Imaging in Therapy Response Assessment and Surveillance of Lung Cancer: Evidenced-based Review With Focus on the Utility of 18F-FDG PET/CT. Clin Lung Cancer. 2020 Jul 03;: Authors: Sheikhbahaei S, Verde F, Hales RK, Rowe SP, Solnes LB Abstract This review covers the state-of-the-art imaging in therapy assessment and surveillance of lung cancer with focus on the utility of fluorine-18 fluorodeoxyglucose positron emission tomography/computed...
Thu Jul 30, 2020 13:23
Related Articles SBRT combined with PD-1/PD-L1 inhibitors in NSCLC treatment: a focus on the mechanisms, advances, and future challenges. J Hematol Oncol. 2020 Jul 28;13(1):105 Authors: Chen Y, Gao M, Huang Z, Yu J, Meng X Abstract Immune checkpoint inhibitors targeting programmed cell death 1 (PD-1), programmed cell death ligand-1 (PD-L1), and others have shown potent clinical efficacy and have revolutionized the treatment protocols of a broad...
Thu Jul 30, 2020 13:23
Related Articles PATIENT VOICES, a project for the integration of the systematic assessment of patient reported outcomes and experiences within a comprehensive cancer center: a protocol for a mixed method feasibility study. Health Qual Life Outcomes. 2020 Jul 28;18(1):252 Authors: Brunelli C, Borreani C, Caraceni A, Roli A, Bellazzi M, Lombi L, Zito E, Pellegrini C, Spada P, Kaasa S, Foschi AM, Apolone G, PATIENT VOICES study group Abstract ...
Thu Jul 30, 2020 13:23
Related Articles Bempegaldesleukin plus nivolumab in untreated, unresectable or metastatic melanoma: Phase III PIVOT IO 001 study design. Future Oncol. 2020 Jul 29;: Authors: Khushalani NI, Diab A, Ascierto PA, Larkin J, Sandhu S, Sznol M, Koon HB, Jarkowski A, Zhou M, Statkevich P, Geese WJ, Long GV Abstract Nivolumab, a programmed cell death-1 inhibitor, has demonstrated prolonged survival benefit in patients with advanced melanoma. Bempegaldesleukin...
Thu Jul 30, 2020 13:23
Related Articles The complex role of EZH2 in the tumor microenvironment: opportunities and challenges for immunotherapy combinations. Future Med Chem. 2020 Jul 29;: Authors: Qiu J, Sharma S, Rollins RA, Paul TA Abstract Immune dysfunction in the tumor microenvironment occurs through epigenetic changes in both tumor cells and immune cells that alter transcriptional programs driving cell fate and cell function. Oncogenic activation of the histone...
Thu Jul 30, 2020 13:23
Related Articles Deciphering the vascular labyrinth: role of microRNAs and candidate gene SNPs in brain AVM development - literature review. Neurol Res. 2020 Jul 28;:1-12 Authors: Florian IA, Timiș TL, Ungureanu G, Florian IS, Bălașa A, Berindan-Neagoe I Abstract BACKGROUND: Brain arteriovenous malformations (AVMs) are a relatively infrequent vascular pathology of unknown etiology that, despite their rarity, cause the highest number of hemorrhagic...
Thu Jul 30, 2020 13:23
Related Articles Abscopal effect after hypofractionated radiotherapy in metastatic renal cell carcinoma pretreated with pazopanib. Immunotherapy. 2020 Jul 28;: Authors: Cerbone L, Rebuzzi SE, Lattanzi E, Gnetti L, Iaia ML, D'Abbiero N, Buti S Abstract Background: The abscopal effect consists of distant metastases response after local treatment based on systemic immune stimulation. It is a rare event observed in many tumors, especially with radiotherapy...
Thu Jul 30, 2020 13:23
Related Articles Pre-treatment prediction of early response to chemoradiotherapy by quantitative analysis of baseline staging FDG-PET/CT and MRI in locally advanced cervical cancer. Acta Radiol. 2020 Jul 28;:284185120943046 Authors: Min LA, Ackermans LL, Nowee ME, Griethuysen JJV, Roberti S, Maas M, Vogel WV, Beets-Tan RG, Lambregts DM Abstract BACKGROUND: Early prediction of response to concurrent chemoradiotherapy (cCRT) could aid to further...
Thu Jul 30, 2020 13:23
Related Articles The relationship between methionine synthase rs1805087 polymorphism and hematological cancers risk. Future Oncol. 2020 Jul 29;: Authors: Bai Y, Drokow EK, Waqas Ahmed HA, Song J, Akpabla GS, Kumah MA, Agyekum EB, Neku EA, Sun K Abstract Background: The relationship between hematological cancer susceptibility and methionine synthase MTR A2756G (rs1805087) polymorphism is inconclusive based on data from past studies. Hence, this...
Thu Jul 30, 2020 13:23
Related Articles Vape shop owners/managers' opinions about FDA regulation of e-cigarettes. Nicotine Tob Res. 2020 Jul 29;: Authors: Berg CJ, Barker DC, Sussman S, Getachew B, Pulvers K, Wagener TL, Hayes RB, Henriksen L Abstract INTRODUCTION: In the US, prominent sources of vaping products are specialty vape shops, which are subject to Food and Drug Administration (FDA) regulation. This study interviewed vape shop owners/managers to assess:...
Thu Jul 30, 2020 13:23
Related Articles Laparoscopic vs. open mesorectal excision for rectal cancer: Are these approaches still comparable? A systematic review and meta-analysis. PLoS One. 2020;15(7):e0235887 Authors: Conticchio M, Papagni V, Notarnicola M, Delvecchio A, Riccelli U, Ammendola M, Currò G, Pessaux P, Silvestris N, Memeo R Abstract BACKGROUND: To analyze pathologic and perioperative outcomes of laparoscopic vs. open resections for rectal cancer performed...
Thu Jul 30, 2020 13:23
Related Articles Understanding the Mechanisms of Diet and Outcomes in Colon, Prostate, and Breast Cancer; Malignant Gliomas; and Cancer Patients on Immunotherapy. Nutrients. 2020 Jul 26;12(8): Authors: Mann S, Sidhu M, Gowin K Abstract Cancer patients often ask which foods would be best to consume to improve outcomes. This is a difficult question to answer as there are no case-controlled, prospective studies that control for confounding factors....
Thu Jul 30, 2020 13:23
Related Articles Hematopoietic Stem Cell Transplantation in Neuromyelitis Optica-Spectrum Disorders (NMO-SD): State-of-the-Art and Future Perspectives. Int J Mol Sci. 2020 Jul 26;21(15): Authors: Ceglie G, Papetti L, Valeriani M, Merli P Abstract Neuromyelitis optica (NMO) and neuromyelitis optica spectrum disorders (NMOSD) are a group of autoimmune inflammatory disorders of the central nervous system (CNS). Understanding of the molecular basis...
Thu Jul 30, 2020 13:23
Related Articles Targeting the Tumor Microenvironment in Neuroblastoma: Recent Advances and Future Directions. Cancers (Basel). 2020 Jul 25;12(8): Authors: Joshi S Abstract Neuroblastoma (NB) is the most common pediatric tumor malignancy that originates from the neural crest and accounts for more than 15% of all the childhood deaths from cancer. The neuroblastoma cancer research has long been focused on the role of MYCN oncogene amplification...
Thu Jul 30, 2020 13:23
Related Articles Molecular Tracing of SARS-CoV-2 in Italy in the First Three Months of the Epidemic. Viruses. 2020 Jul 24;12(8): Authors: Lai A, Bergna A, Caucci S, Clementi N, Vicenti I, Dragoni F, Cattelan AM, Menzo S, Pan A, Callegaro A, Tagliabracci A, Caruso A, Caccuri F, Ronchiadin S, Balotta C, Zazzi M, Vaccher E, Clementi M, Galli M, Zehender G Abstract The aim of this study is the characterization and genomic tracing by phylogenetic...
Thu Jul 30, 2020 13:23
Related Articles Comprehensive Genomic Analysis Reveals the Prognostic Role of LRRK2 Copy-Number Variations in Human Malignancies. Genes (Basel). 2020 Jul 24;11(8): Authors: Lopez G, Lazzeri G, Rappa A, Isimbaldi G, Cribiù FM, Guerini-Rocco E, Ferrero S, Vaira V, Di Fonzo A Abstract Genetic alterations of leucine-rich repeat kinase 2 (LRRK2), one of the most important contributors to familial Parkinson's disease (PD), have been hypothesized...
Thu Jul 30, 2020 13:23
Related Articles Evaluation of the Diagnostic and Predicative Values of 8-Iso-Prostaglandin F2α as a Biomarker of Breast Cancer. Oncol Res Treat. 2020 Jul 28;:1-9 Authors: Nour Eldin EEM, Nour Eldein MM, El-Readi MZ, Mirza AA, Fatani SH, Al-Amodi HS, Althubiti MA, Al-Ezzi EM, Eid SY, Kamel HFM Abstract BACKGROUND: Breast cancer (BC) is a commonly reported cancer that is widely prevalent among women. Its early detection improves patient survival...
Thu Jul 30, 2020 13:23
Related Articles Physics and biology of ultrahigh dose-rate (FLASH) radiotherapy: a topical review. Phys Med Biol. 2020 Jul 28;: Authors: Esplen NM, Mendonca MS, Bazalova-Carter M Abstract Ultrahigh dose-rate (>40 Gy/s) radiotherapy, or "FLASH" therapy, has gained significant momentum since the publication by Favaudon et al. in 2014, in which reduced normal tissue toxicity and similar tumor control for ultrahigh dose-rate radiotherapy compared...
Thu Jul 30, 2020 13:23
Related Articles Comparison of induction chemotherapy plus concurrent chemoradiotherapy and induction chemotherapy plus radiotherapy in locally advanced nasopharyngeal carcinoma. Oral Oncol. 2020 Jul 25;111:104925 Authors: Wang Q, Xu G, Xia Y, Zuo J, Zeng G, Xue Z, Cao R, Xiong W, Li W Abstract BACKGROUND: Induction chemotherapy plus concurrent chemoradiotherapy (IC + CCRT) is a standard treatment regimen for locally advanced nasopharyngeal...
Thu Jul 30, 2020 13:23
Related Articles Towards standardized purification of bacterial magnetic nanoparticles for future in vivo applications. Acta Biomater. 2020 Jul 25;: Authors: Rosenfeldt S, Mickoleit F, Jörke C, Clement JH, Markert S, Jérôme V, Schwarzinger S, Freitag R, Schüler D, Uebe R, Schenk AS Abstract Bacterial magnetosomes (MS) are well-defined membrane-enveloped single-domain iron oxide (magnetite) nanoparticles, which are susceptible to genetic and...
Thu Jul 30, 2020 13:23
Related Articles Implementing a Clinic-Based Telehealth Support Service (FamilyStrong) for Family Caregivers of Individuals with Grade IV Brain Tumors. J Palliat Med. 2020 Jul 24;: Authors: Dionne-Odom JN, Williams GR, Warren PP, Tims S, Huang CS, Taylor RA, Ledbetter L, Lever T, Mitchell K, Thompson M, Dosse C, Engler S, Holmes A, Connelley B, Hicks J, Bakitas MA, Nabors B, Tucker R Abstract Background: Nearly 3 million U.S. family caregivers...
Thu Jul 30, 2020 13:23
113 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: "Oncol Lett"[jour] These pubmed results were generated on 2020/07/30PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
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Related Articles Osteonecrosis of the jaw and dental extractions: a single-center experience. Oral Surg Oral Med Oral Pathol Oral Radiol. 2020 Jul 08;: Authors: Sandhu S, Salous MH, Sankar V, Margalit DN, Villa A Abstract OBJECTIVE: The aim of this study was to investigate the frequency of osteoradionecrosis/medication-related osteonecrosis of the jaw (ORN/MRONJ) after dental extraction with use of postextraction antibiotic coverage without...
Thu Jul 30, 2020 15:58
Related Articles Adaptations of a Tertiary Otorhinolaryngology Head and Neck Surgery Department in Singapore during the COVID-19 Outbreak. Ann Otol Rhinol Laryngol. 2020 Jul 29;:3489420946779 Authors: See A, Go LK, Teo CEH, Teo NWY, Toh ST Abstract PURPOSE: The novel coronavirus 2019 (COVID-19) outbreak which was first reported in Wuhan, China has been declared a pandemic by the World Health Organization on March 11, 2020. Otorhinolaryngologists...
Thu Jul 30, 2020 15:06
Azygos Vein Aneurysm with Thrombosis and Aspergillus fumigatus Diagnosed Using Bronchoscopy: Case Report. Am J Case Rep. 2020 Jul 29;21:e923401 Authors: Briones-Claudett KH, Briones-Claudett MH, Posligua Moreno A, López Briones BJ, Briones Zamora KH, Briones Marquez DC, Bemites Sólis J, Crespo JS, Grunauer M Abstract BACKGROUND The venous system of the posterior thoracic wall merges into a single trunk called the azygos vein, located in the...
Thu Jul 30, 2020 14:10
Related Articles Superior Mesenteric Artery Thrombosis and Acute Intestinal Ischemia as a Consequence of COVID-19 Infection. Am J Case Rep. 2020 Jul 29;21:e925753 Authors: Cheung S, Quiwa JC, Pillai A, Onwu C, Tharayil ZJ, Gupta R Abstract BACKGROUND The novel COVID-19 disease caused by the SARS-CoV-2 virus is a highly infectious disease that originated in Wuhan, China, and has rapidly spread throughout the world. In addition to respiratory...
Thu Jul 30, 2020 14:10
Related Articles Use of a Titanium Cage and Intramedullary Nails to Treat Distal Femoral Fracture Nonunion in a Patient with Renal Osteopathy: A Case Report. Am J Case Rep. 2020 Jul 29;21:e924565 Authors: Jin H, Xiong M, Zhou H, Zhang M, He X, Pu D Abstract BACKGROUND Nonunion occurs to approximately 10% of people who suffer from distal femoral fracture, which can be induced by other diseases and medical interventions. CKD and subsequent renal...
Thu Jul 30, 2020 14:10
Related Articles Value of the Frontal Assessment Battery Tool for Assessing the Frontal Lobe Function in Stroke Patients. Ann Rehabil Med. 2020 Jul 28;: Authors: Han M, Kim DY, Leigh JH, Kim MW Abstract Objective: To examine the correlation between the Frontal Assessment Battery (FAB) test, which is used to assess the frontal lobe function, and anatomical lesions as well as the ability of the test to detect frontal lobe dysfunction. ...
Thu Jul 30, 2020 13:54
Related Articles Ultrasound Imaging of the Trunk Muscles in Acute Stroke Patients and Relations With Balance Scales. Ann Rehabil Med. 2020 Jul 28;: Authors: Kim Y, Kim J, Nam H, Kim HD, Eom MJ, Jung SH, Han N Abstract Objective: To examine the correlation between ultrasonographic trunk muscle parameters and balance scales in mild acute stroke patients. Methods: A total of 55 stroke patients with hemiparesis and motor power grade ≥4...
Thu Jul 30, 2020 13:54
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