Osteoporosis is a disease characterized by deterioration of bone tissue and mass, with an increasing global prevalence. Therefore, the discovery of biomarkers for osteoporosis would help to guide appropriate treatment. Circulating microRNAs (miRNAs) have become increasingly recognized as biomarkers for detecting diseases. However, few studies have investigated the association of circulating miRNA with osteoporosis in the general population. The aim of this study was to identify miRNA associated with...
Thu Jul 30, 2020 17:35
This study aims at exploring the clinical efficacy and sonographic changes of photodynamic therapy (PDT) using Hematoporphyrin Monomethyl Ether (HMME) for the treatment of port-wine stains (PWS). Forty-five patients with PWS were recruited between March 2017 and June 2018 from the Department of Dermatology of The Third Affiliated Hospital of Soochow University. Five cases were of the pink type, thirty-nine cases were of the purple-red type, and one case was of the thickened type. All patients received...
Thu Jul 30, 2020 17:05
MitoTEMPO, a mitochondrial antioxidant, has protective effects on liver-related diseases. However, the role of MitoTEMPO on nonalcoholic fatty liver disease (NAFLD) and its possible mechanisms are largely unknown. Here, we investigated the effects of MitoTEMPO on NAFLD using high fat diet- (HFD-) induced obese mice as animal models. MitoTEMPO was intraperitoneally injected into HFD mice. Liver morphological changes were observed by H&E and Oil Red O staining, and the frequency of MDSCs in peripheral...
Thu Jul 30, 2020 09:50
Background. Neighborhood destinations play important roles in daily activity levels of older adults. However, little is known about how specific destinations are associated with these activities and/or sedentary behaviors, especially in Asia. This study investigated how neighborhood destinations were associated with physical activity recommendations and excessive sedentary time among older adults. Methods. A telephone-based survey was conducted to collect cross-sectional data on the sociodemographic...
Thu Jul 30, 2020 08:50
Objective. MicroRNAs play vital roles in the development of endometriosis. It is reported that miR-200b-3p is downregulated in endometriosis, although its mechanisms in this disease remain still unclear. Therefore, the purpose of this study was to explore the function and potential regulatory network of miR-200b-3p in endometriosis through database analysis. Methods. The endometriosis gene expression profiles were downloaded from the GEO database to screen differentially expressed genes (DEGs). The...
Thu Jul 30, 2020 08:50
Objective. The aim of this study was to investigate the respective correlation between the height () of a posterior malleolar fracture (PMF) and the involved area () of an articular surface and the presence of “die-punch.” Methods. Patients with closed posterior malleolar fractures admitted to our hospital from January 2015 to December 2017 were selected, with complete X-ray and 3D reconstruction CT imaging data. The gender, age, injured side, and surgical fixation methods of the patients were recorded....
Thu Jul 30, 2020 08:50
Minimally invasive surgery has played a huge role in improving patient outcomes, and reducing morbidity and recovery times compared with traditional surgical techniques. However, it can be a little tricky for surgeons to operate through tiny incisions and use complicated equipment, meaning that there is often a significant learning curve and training period involved. Robotics is well suited to aiding surgeons in minimally invasive surgery and surgical robots have made an impact on...
Thu Jul 30, 2020 23:24
Wearable biomedical devices hold the promise of allowing for continuous, remote patient monitoring in all kinds of settings. A variety of vital signs, including heart rate and its variability, body temperature, and the amount of sweat produced, can be measured. The problem is that a lot of these measurements are not particularly accurate when using devices that are made to stick to or wrap around a part of the body. The sensors tend to not conform to the skin as it flexes and move slightly...
Thu Jul 30, 2020 19:42
The need for emergency medical services (EMS) outside of the hospital setting is on the rise, with an estimated 240 millions 9-1-1 calls made in the US annually. While medical equipment used in this setting must be available, manipulable, and able to share important data across a variety of unknown situations, historically it has been cumbersome and limited in its connectivity. Philips’ Tempus ALS solution including the Tempus Pro monitor (left) and Tempus LS defibrillator (right)....
Thu Jul 30, 2020 17:11
Mollusc shells are an abundant resource that have been long used to predict the structures of ancient ecological communities, examine evolutionary processes, reconstruct paleoenvironmental conditions, track and predict responses to climatic change, and explore the movement of hominids across the globe. Despite the ubiquity of mollusc shell in many environments, it remains relatively unexplored as a substrate for molecular genetic analysis. Here we undertook a series of experiments using the New Zealand...
Thu Jul 30, 2020 03:00
The term schizotypy refers to a group of stable personality traits with attributes similar to symptoms of schizophrenia, usually classified in terms of positive, negative or cognitive disorganization symptoms. The observation of increased spreading of semantic activation in individuals with schizotypal traits has led to the hypothesis that thought disorder, one of the characteristics of cognitive disorganization, stems from semantic disturbances. Nevertheless, it is still not clear under which specific...
Thu Jul 30, 2020 03:00
Coffee beans derived from feces of the civet cat are used to brew coffee known as kopi luwak (the Indonesian words for coffee and palm civet, respectively), which is one of the most expensive coffees in the world owing to its limited supply and strong market demand. Recent metabolomics studies have revealed that kopi luwak metabolites differ from metabolites found in other coffee beans. To produce kopi luwak, coffee beans are first eaten by civet cats. It has been proposed that fermentation inside...
Thu Jul 30, 2020 03:00
River discharges are often predicted based on a calibrated rainfall-runoff model. The major sources of uncertainty, namely input, parameter and model structural uncertainty must all be taken into account to obtain realistic estimates of the accuracy of discharge predictions. Over the past years, Bayesian calibration has emerged as a suitable method for quantifying uncertainty in model parameters and model structure, where the latter is usually modelled by an additive or multiplicative stochastic...
Thu Jul 30, 2020 03:00
Background Gastric cancer (GC) is one of the most fatal cancers in the world. Results of previous studies on the association of the CpG island methylator phenotype (CIMP) with GC prognosis are conflicting and mainly based on selected CIMP markers. The current study attempted to comprehensively assess the association between CIMP status and GC survival and to develop a CIMP-related prognostic gene signature of GC. Methods We used a hierarchical clustering method based on 2,082 GC-related...
Thu Jul 30, 2020 03:00
Objectives The objective of this study was to compare maxillary dimensions and growth in newborns with Complete Unilateral Cleft Lip and Palate (UCLP) to healthy newborns before and after cheiloplasty. Additionally, a palatal growth curve is constructed to give more information about the natural growth before surgical intervention. Methods Twenty-eight newborns with complete UCLP were enrolled in this study. Multiple...
Thu Jul 30, 2020 03:00
Background In pandemics, because of increased demand and subsequent shortage of commercial facemasks, people need to use cloth facemasks, although such masks are reported to provide reduced protection. These masks can be prepared in local levels from different fabric materials. In developing countries, cloth masks are preferable because of low cost and added advantages of reusability. The filtering performance of a cloth facemask depends on the facial fit and on the material properties of fabrics...
Thu Jul 30, 2020 03:00
Publication date: Available online 30 July 2020Source: International Journal of Radiation Oncology*Biology*PhysicsAuthor(s): M. Marcello, J.W. Denham, A. Kennedy, A. Haworth, A. Steigler, P.B. Greer, L.C. Holloway, J.A. Dowling, M.G. Jameson, D. Roach, D.J. Joseph, S.L. Gulliford, D.P. Dearnaley, M.R. Sydes, E. Hall, M.A. Ebert
Thu Jul 30, 2020 17:09
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