Cancer Cytopathology

Diagnostic performances of the Afirma gene sequencing classifier in comparison with the gene expression classifier: A meta‐analysis

The Afirma microarray‐based Gene Expression Classifier (GEC) with its high negative predictive value (NPV) and sensitivity has been used to rule out cancer from thyroid nodules with an indeterminate cytology but not to rule in cancer because of its low positive predictive value (PPV) and specificity. The Gene Sequencing Classifier (GSC) has been reported to improve on the weakness of GEC. In this study, a meta‐analysis was performed to compare the clinical impact and diagnostic performance of GEC...

Cancer Cytopathology

Wed Jul 29, 2020 13:44

Mark above section as read

 Clinical Anatomy

Anatomical relationship between the accessory process of the lumbar spine and the pedicle screw entry point.

Abstract Introduction The vertebra accessory process (or tubercle) of the lumbar spine is an understated landmark which lies caudal to the mammillary process at the base of the transverse process. To our knowledge, no studies compare its relation to pedicle entry point for screw placement. We proposed to evaluate whether a valid and reliable relationship exists between the accessory process and the projected pedicle axis. Material and Methods The distance between the tip of the accessory...

Clinical Anatomy

Wed Jul 29, 2020 18:44

Mark above section as read

 Pathology International

Utility of highly expressed EZH2 in pleural effusion cytology for the diagnosis of mesothelioma

Pathology International

Wed Jul 29, 2020 16:34

Mark above section as read

 ScienceDirect Publication: Pathology - Research and Practice

High expression of G protein subunit gamma 13 is associated with poor prognosis of gastrointestinal stromal tumor

Publication date: Available online 30 July 2020Source: Pathology - Research and PracticeAuthor(s): Ke-Cheng Ju, Bin Zhang, Yi-Lin Hu, Ying Feng, Xiao-Hong Li, Yi-Fei Liu, Peng Li, Qin-Sheng Mao, Wan-Jiang Xue

ScienceDirect Publication: Pathology - Research and Practice

Thu Jul 30, 2020 18:56

IL1RAP regulated by PRPRD promotes gliomas progression via inducing neuronal synapse development and neuron differentiation in vitro

Publication date: Available online 30 July 2020Source: Pathology - Research and PracticeAuthor(s): Feng Li, Weifeng Zhang, Ming Wang, Pifeng Jia

ScienceDirect Publication: Pathology - Research and Practice

Thu Jul 30, 2020 18:56

Quantitative assessment of optical clearing methods on formalin-fixed human lymphoid tissue

Publication date: Available online 30 July 2020Source: Pathology - Research and PracticeAuthor(s): Yvonne Schega, Nadine Flinner, Martin-Leo Hansmann

ScienceDirect Publication: Pathology - Research and Practice

Thu Jul 30, 2020 18:56

Primary Squamous Cell Carcinoma of Thyroid with a Novel BRAF mutation and High PDL-1 Expression: A Case Report with Treatment Implications and Review of Literature

Publication date: Available online 30 July 2020Source: Pathology - Research and PracticeAuthor(s): Mary Torrez, Ryan C Braunberger, Emrullah Yilmaz, Shweta Agarwal

ScienceDirect Publication: Pathology - Research and Practice

Thu Jul 30, 2020 18:56

Roles of estrogen receptor α and β in the regulation of proliferation in endometrial carcinoma

Publication date: Available online 30 July 2020Source: Pathology - Research and PracticeAuthor(s): Guanli Hu, Jingbo Zhang, Xueyan Zhou, Jianwei Liu, Qing Wang, Bei Zhang

ScienceDirect Publication: Pathology - Research and Practice

Thu Jul 30, 2020 18:56

Mark above section as read

 The Journal of Pathology

Phospholipase D1 inhibition sensitizes glioblastoma to temozolomide and suppresses its tumorigenicity

Abstract Resistance of glioblastoma to the chemotherapeutic compound temozolomide is associated with the presence of glioblastoma stem cells in glioblastoma and is a key obstacle for the poor prognosis of glioblastoma. Here, we show that phospholipase D1 is elevated in CD44High glioblastoma stem cells and in glioblastoma, especially recurring glioblastoma. Phospholipase D1 elevation positively correlated with the level of CD44 and poor prognosis in glioblastoma patients. Temozolomide significantly...

The Journal of Pathology

Wed Jul 29, 2020 22:49

Mark above section as read