Nutrients, Vol. 12, Pages 2299: Casein Protein Processing Strongly Modulates Post-Prandial Plasma Amino Acid Responses In Vivo in Humans Nutrients doi: 10.3390/nu12082299 Authors: Jorn Trommelen Michelle E. G. Weijzen Janneau van Kranenburg Renate A. Ganzevles Milou Beelen Lex B. Verdijk Luc J. C. van Loon Micellar casein is characterized as a slowly digestible protein source, and its structure can be modulated by various food processing techniques to modify its functional...
Nutrients, Vol. 12, Pages 2298: Lactobacillus reuteri Ameliorates Intestinal Inflammation and Modulates Gut Microbiota and Metabolic Disorders in Dextran Sulfate Sodium-Induced Colitis in Mice Nutrients doi: 10.3390/nu12082298 Authors: Gang Wang Shuo Huang Shuang Cai Haitao Yu Yuming Wang Xiangfang Zeng Shiyan Qiao Lactobacillus reuteri, a commensal intestinal bacteria, has various health benefits including the regulation of immunity and intestinal microbiota. We examined...
Nutrients, Vol. 12, Pages 2297: Serum Iron and Risk of Diabetic Retinopathy Nutrients doi: 10.3390/nu12082297 Authors: Ying-Jen Chen Jiann-Torng Chen Ming-Cheng Tai Chang-Min Liang Yuan-Yuei Chen Wei-Liang Chen Background: Diabetic retinopathy (DR) is indicated as a major cause of blindness in the world. Emerging evidence supports the interaction of iron metabolism with diabetes. However, little research is available concerning the relationship between iron metabolism...
Nutrients, Vol. 12, Pages 2296: The Use of Curcumin as a Complementary Therapy in Ulcerative Colitis: A Systematic Review of Randomized Controlled Clinical Trials Nutrients doi: 10.3390/nu12082296 Authors: Mariana Roque Coelho Marcela Diogo Romi Daniele Masterson Tavares Pereira Ferreira Cyrla Zaltman Marcia Soares-Mota The objective of this study was to systematically review the literature to verify the efficacy and safety of curcumin as a complementary therapy for the maintenance...
Nutrients, Vol. 12, Pages 2292: Differential Effects of Chronic Ingestion of Refined Sugars versus Natural Sweeteners on Insulin Resistance and Hepatic Steatosis in a Rat Model of Diet-Induced Obesity Nutrients doi: 10.3390/nu12082292 Authors: Marion Valle Philippe St-Pierre Geneviève Pilon André Marette While the detrimental effect of refined sugars on health has been the subject of many investigations, little is known about the long-term impact of natural sweeteners on metabolic...
Nutrients, Vol. 12, Pages 2293: Euglena Gracilis and β-Glucan Paramylon Induce Ca2+ Signaling in Intestinal Tract Epithelial, Immune, and Neural Cells Nutrients doi: 10.3390/nu12082293 Authors: Yasuda Nakashima Murata Suzuki Adachi The intestinal tract contains over half of all immune cells and peripheral nerves and manages the beneficial interactions between food compounds and the host. Paramylon is a β-1,3-glucan storage polysaccharide from Euglena gracilis...
Nutrients, Vol. 12, Pages 2294: The Quality of Breakfast and Healthy Diet in School-aged Adolescents and Their Association with BMI, Weight Loss Diets and the Practice of Physical Activity Nutrients doi: 10.3390/nu12082294 Authors: Raquel M. Guevara José D. Urchaga Antonio S. Cabaco José E. Moral-García Dietary habits are an important factor in the protection of adolescent health. The quality and frequency of breakfast and the various food groups can affect the wellbeing of...
Nutrients, Vol. 12, Pages 2295: Ergogenic Effect of BCAAs and L-Alanine Supplementation: Proof-of-Concept Study in a Murine Model of Physiological Exercise Nutrients doi: 10.3390/nu12082295 Authors: Paola Mantuano Gianluca Bianchini Ornella Cappellari Brigida Boccanegra Elena Conte Francesca Sanarica Antonietta Mele Giulia M. Camerino Laura Brandolini Marcello Allegretti Michela De Bellis Andrea Aramini Annamaria De Luca Background: Branched-chain...
Nutrients, Vol. 12, Pages 2286: Low Vitamin D Levels and Frailty Status in Older Adults: A Systematic Review and Meta-Analysis Nutrients doi: 10.3390/nu12082286 Authors: Diego Marcos-Pérez María Sánchez-Flores Stefania Proietti Stefano Bonassi Solange Costa Joao Paulo Teixeira Juan Fernández-Tajes Eduardo Pásaro Vanessa Valdiglesias Blanca Laffon Serum vitamin D deficiency is widespread among older adults and is a potential modifiable risk factor for frailty....
Nutrients, Vol. 12, Pages 2287: Malnutrition Screening and Assessment in the Cancer Care Ambulatory Setting: Mortality Predictability and Validity of the Patient-Generated Subjective Global Assessment Short form (PG-SGA SF) and the GLIM Criteria Nutrients doi: 10.3390/nu12082287 Authors: Lynette M. De Groot Gahee Lee Antoinette Ackerie Barbara S. van der Meij Background: A valid malnutrition screening tool (MST) is essential to provide timely nutrition support in ambulatory...
Nutrients, Vol. 12, Pages 2289: Changes of Physical Activity and Ultra-Processed Food Consumption in Adolescents from Different Countries during Covid-19 Pandemic: An Observational Study Nutrients doi: 10.3390/nu12082289 Authors: María Belén Ruíz-Roso Patricia de Carvalho Padilha Diana C. Matilla-Escalante Paola Brun Natalia Ulloa Diofanor Acevedo-Correa Wilza Arantes Ferreira Peres Miquel Martorell Thais Rangel Bousquet Carrilho Letícia de Oliveira Cardoso Fernanda...
Nutrients, Vol. 12, Pages 2291: Exploring Health-Promoting Attributes of Plant Proteins as a Functional Ingredient for the Food Sector: A Systematic Review of Human Interventional Studies Nutrients doi: 10.3390/nu12082291 Authors: Marta Lonnie Ieva Laurie Madeleine Myers Graham Horgan Wendy R. Russell Alexandra M. Johnstone The potential beneficial effects of plant-based diets on human health have been extensively studied. However, the evidence regarding the health effects...
Nutrients, Vol. 12, Pages 2288: Underlying Susceptibility to Eating Disorders and Drug Abuse: Genetic and Pharmacological Aspects of Dopamine D4 Receptors Nutrients doi: 10.3390/nu12082288 Authors: Luca Botticelli Emanuela Micioni Di Bonaventura Fabio Del Bello Gianfabio Giorgioni Alessandro Piergentili Adele Romano Wilma Quaglia Carlo Cifani Maria Vittoria Micioni Di Bonaventura The dopamine D4 receptor (DRD4) has a predominant expression in the prefrontal cortex...
Nutrients, Vol. 12, Pages 2290: Is Caloric Restriction Associated with Better Healthy Aging Outcomes? A Systematic Review and Meta-Analysis of Randomized Controlled Trials Nutrients doi: 10.3390/nu12082290 Authors: Silvia Caristia Marta De Vito Andrea Sarro Alessio Leone Alessandro Pecere Angelica Zibetti Nicoletta Filigheddu Patrizia Zeppegno Flavia Prodam Fabrizio Faggiano Paolo Marzullo Background: Global dietary patterns have gradually shifted toward...
Nutrients, Vol. 12, Pages 2285: Impact of Protein Intake in Older Adults with Sarcopenia and Obesity: A Gut Microbiota Perspective Nutrients doi: 10.3390/nu12082285 Authors: Konstantinos Prokopidis Mavil May Cervo Anoohya Gandham David Scott The continuous population increase of older adults with metabolic diseases may contribute to increased prevalence of sarcopenia and obesity and requires advocacy of optimal nutrition treatments to combat their deleterious outcomes. Sarcopenic...
Nutrients, Vol. 12, Pages 2284: Dietary Supplement Use among Non-athlete Students at a Canadian University: A Pilot-Survey Nutrients doi: 10.3390/nu12082284 Authors: Dalia El Khoury Joel Hansen Madelyn Tabakos Lawrence L. Spriet Paula Brauer Despite the emerging evidence of adverse consequences and interaction with doping substances, dietary supplements (DS) are commonly used by many Canadians. The purpose of this study was to evaluate the patterns and determinants of current...
Nutrients, Vol. 12, Pages 2282: Sulforaphane Diminishes the Formation of Mammary Tumors in Rats Exposed to 17β-Estradiol Nutrients doi: 10.3390/nu12082282 Authors: Dushani L. Palliyaguru Li Yang Dionysios V. Chartoumpekis Stacy G. Wendell Marco Fazzari John J. Skoko Yong Liao Steffi Oesterreich George K. Michalopoulos Thomas W. Kensler Elevated levels of estrogen are a risk factor for breast cancer. In addition to inducing DNA damage, estrogens can enhance...
Nutrients, Vol. 12, Pages 2283: Response of Vitamin D after Magnesium Intervention in a Postmenopausal Population from the Province of Granada, Spain Nutrients doi: 10.3390/nu12082283 Authors: Héctor Vázquez-Lorente Lourdes Herrera-Quintana Jorge Molina-López Yenifer Gamarra-Morales Beatriz López-González Claudia Miralles-Adell Elena Planells Menopause is a stage of hormonal imbalance in women which, in addition to other physiopathological consequences, poses a risk...
Nutrients, Vol. 12, Pages 2281: A Prospective Clinical Trial of Prolonged Fasting in Healthy Young Males and Females—Effect on Fatigue, Sleepiness, Mood and Body Composition Nutrients doi: 10.3390/nu12082281 Authors: Boya Nugraha Amin Riat Samaneh Khoshandam Ghashang Luqman Eljurnazi Christoph Gutenbrunner Fasting during a long period (17–18 h/day) may affect daily performance. Fatigue is one of important parameters to observe for this effect. This study aimed to...
Nutrients, Vol. 12, Pages 2280: How Does Time Use Differ between Individuals Who Do More versus Less Foodwork? A Compositional Data Analysis of Time Use in the United Kingdom Time Use Survey 2014–2015 Nutrients doi: 10.3390/nu12082280 Authors: Chloe Clifford Astbury Louise Foley Tarra L. Penney Jean Adams Background: Increased time spent on home food preparation is associated with higher diet quality, but a lack of time is often reported as a barrier to this practice. We compared...
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Particles, Vol. 3, Pages 562-575: Quantum Effects on the Mesoscale Particles doi: 10.3390/particles3030038 Authors: Tatiana A. Khantuleva Victor M. Kats In different areas of mechanics, highly non-equilibrium processes are accompanied by self-organization of various type turbulent structures and localized inhomogeneities at intermediate scale between macro and micro levels. In order to describe the self-organization of the new dynamic structures on the mesoscale, a new problem formulation...
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Pathogens, Vol. 9, Pages 623: Detection of Epstein-Barr Virus DNA in Gastric Biopsies of Pediatric Patients with Dyspepsia Pathogens doi: 10.3390/pathogens9080623 Authors: Abigail Morales-Sánchez Javier Torres María G. Cardenas-Mondragón Carolina Romo-González Margarita Camorlinga-Ponce Lourdes Flores-Luna Ezequiel M. Fuentes-Pananá In this study, we assessed the presence of Epstein-Barr virus (EBV) in gastric samples derived from pediatric patients with dyspeptic symptoms,...
Pathogens, Vol. 9, Pages 622: Investigation of Macrolide Resistance Genotypes in Mycoplasma bovis Isolates from Canadian Feedlot Cattle Pathogens doi: 10.3390/pathogens9080622 Authors: Andrea Kinnear Tim A. McAllister Rahat Zaheer Matthew Waldner Antonio C. Ruzzini Sara Andrés-Lasheras Sarah Parker Janet E. Hill Murray D. Jelinski Mycoplasma bovis is associated with bovine respiratory disease (BRD) and chronic pneumonia and polyarthritis syndrome (CPPS) in feedlot...
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Pharmaceuticals, Vol. 13, Pages 174: Receptors and Channels Possibly Mediating the Effects of Phytocannabinoids on Seizures and Epilepsy Pharmaceuticals doi: 10.3390/ph13080174 Authors: Lara Senn Giuseppe Cannazza Giuseppe Biagini Epilepsy contributes to approximately 1% of the global disease burden. By affecting especially young children as well as older persons of all social and racial variety, epilepsy is a present disorder worldwide. Currently, only 65% of epileptic patients...
Pharmaceuticals, Vol. 13, Pages 172: Evaluation of EphB4 as Target for Image-Guided Surgery of Breast Cancer Pharmaceuticals doi: 10.3390/ph13080172 Authors: Cansu de Muijnck Yoren van Gorkom Maurice van Duijvenvoorde Mina Eghtesadi Geeske Dekker-Ensink Shadhvi S. Bhairosingh Alessandra Affinito Peter J. K. Kuppen Alexander L. Vahrmeijer Cornelis F. M. Sier Background: Targeted image-guided surgery is based on the detection of tumor cells after administration...
Pharmaceuticals, Vol. 13, Pages 173: Current State of Radiolabeled Heterobivalent Peptidic Ligands in Tumor Imaging and Therapy Pharmaceuticals doi: 10.3390/ph13080173 Authors: Benedikt Judmann Diana Braun Björn Wängler Ralf Schirrmacher Gert Fricker Carmen Wängler Over the past few years, an approach emerged that combines different receptor-specific peptide radioligands able to bind different target structures on tumor cells concomitantly or separately. The reason for...
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Pharmaceutics, Vol. 12, Pages 715: Co-Amorphization of Kanamycin with Amino Acids Improves Aerosolization Pharmaceutics doi: 10.3390/pharmaceutics12080715 Authors: Bishal Raj Adhikari Kārlis Bērziņš Sara J. Fraser-Miller Keith C. Gordon Shyamal C. Das Different formulation techniques have been investigated to prepare highly aerosolizable dry powders to deliver a high dose of antibiotics to the lung for treating local infections. In this study, we investigated the influence...
Pharmaceutics, Vol. 12, Pages 717: Biopharmaceutical Assessment of Dexamethasone Acetate-Based Hydrogels Combining Hydroxypropyl Cyclodextrins and Polysaccharides for Ocular Delivery Pharmaceutics doi: 10.3390/pharmaceutics12080717 Authors: Roseline Mazet Xurxo García-Otero Luc Choisnard Denis Wouessidjewe Vincent Verdoot Frédéric Bossard Victoria Díaz-Tomé Véronique Blanc-Marquis Francisco-Javier Otero-Espinar Anxo Fernandez-Ferreiro Annabelle Gèze We previously...
Pharmaceutics, Vol. 12, Pages 716: Lead Compounds in the Context of Extracellular Vesicle Research Pharmaceutics doi: 10.3390/pharmaceutics12080716 Authors: Thao T.D. Tran Phuong H.L. Tran Studies of small extracellular vesicles (sEVs), known as exosomes, have been flourishing in the last decade with several achievements, from advancing biochemical knowledge to use in biomedical applications. Physiological changes of sEVs due to the variety of cargos they carry undoubtedly leave an...
Pharmaceutics, Vol. 12, Pages 714: Slower Elimination of Tofacitinib in Acute Renal Failure Rat Models: Contribution of Hepatic Metabolism and Renal Excretion Pharmaceutics doi: 10.3390/pharmaceutics12080714 Authors: Sung Hun Bae Sun-Young Chang So Hee Kim Tofacitinib is a Jak inhibitor developed as a treatment for rheumatoid arthritis. Tofacitinib is metabolized mainly through hepatic CYP3A1/2, followed by CYP2C11. Rheumatoid arthritis tends to increase renal toxicity due to drugs...
Pharmaceutics, Vol. 12, Pages 718: Preparation and Evaluation of Eudragit L100-PEG Proliponiosomes for Enhanced Oral Delivery of Celecoxib Pharmaceutics doi: 10.3390/pharmaceutics12080718 Authors: Min-Hwan Kim Dong Hyun Kim Duy-Thuc Nguyen Han Sol Lee Nae-Won Kang Min-Jun Baek Jiseon An So-Yeol Yoo Yong-Hyeon Mun Wonhwa Lee Ki-Taek Kim Cheong-Weon Cho Jae-Young Lee Dae-Duk Kim PEGylated Eudragit L100 (ELP)-containing proliponiosomes (PLNs) were...
Pharmaceutics, Vol. 12, Pages 713: Prevalence of Potential Drug–Drug Interaction Risk among Chronic Kidney Disease Patients in a Spanish Hospital Pharmaceutics doi: 10.3390/pharmaceutics12080713 Authors: Gracia Santos-Díaz Ana María Pérez-Pico Miguel Ángel Suárez-Santisteban Vanesa García-Bernalt Raquel Mayordomo Pedro Dorado Chronic kidney disease (CKD) is a major health problem worldwide and, in Spain, it is present in 15.1% of individuals. CKD is frequently associated...
Pharmaceutics, Vol. 12, Pages 712: Formulation and Characterisation of a Combination Captopril and Hydrochlorothiazide Microparticulate Dosage Form Pharmaceutics doi: 10.3390/pharmaceutics12080712 Authors: Mellisa T. R. Chikukwa Roderick B. Walker Sandile M. M. Khamanga Cardiovascular diseases such as hypertension and cardiac failure in South African children and adolescents are effectively managed long term, using a combination treatment of captopril and hydrochlorothiazide. The...
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Pharmacy, Vol. 8, Pages 133: Potentially Inappropriate Drug Prescribing in French Nursing Home Residents: An Observational Study Pharmacy doi: 10.3390/pharmacy8030133 Authors: Soraya Qassemi Arnaud Pagès Laure Rouch Serge Bismuth André Stillmunkes Maryse Lapeyre-Mestre Cécile McCambridge Charlène Cool Philippe Cestac Purpose: To identify the prevalence of potentially inappropriate drug prescription in a sample of nursing home residents in France, combining explicit...
Pharmacy, Vol. 8, Pages 132: From Pilot to Scale, the 5 Year Growth of a Primary Care Pharmacist Model Pharmacy doi: 10.3390/pharmacy8030132 Authors: Jordan Spillane Erika Smith This case report details the five year journey of implementing, growing and optimizing a primary care pharmacist model in the ambulatory clinic setting within a health system. There is published evidence supporting the numerous benefits of including pharmacists in the primary care medical team model. This...
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Plants, Vol. 9, Pages 967: Amino Acid Transporters in Plant Cells: A Brief Review Plants doi: 10.3390/plants9080967 Authors: Guangzhe Yang Qiuxing Wei Hao Huang Jixing Xia Amino acids are not only a nitrogen source that can be directly absorbed by plants, but also the major transport form of organic nitrogen in plants. A large number of amino acid transporters have been identified in different plant species. Despite belonging to different families, these amino acid transporters...
Plants, Vol. 9, Pages 968: Main Challenges and Actions Needed to Improve Conservation and Sustainable Use of Our Crop Wild Relatives Plants doi: 10.3390/plants9080968 Authors: Johannes M.M. Engels Imke Thormann Crop wild relatives (CWR, plural CWRs) are those wild species that are regarded as the ancestors of our cultivated crops. It was only at the end of the last century that they were accorded a high priority for their conservation and, thus, for many genebanks, they are a new...
Plants, Vol. 9, Pages 964: Absence of Polyphenol Oxidase in Cynomorium coccineum, a Widespread Holoparasitic Plant Plants doi: 10.3390/plants9080964 Authors: Alessandra Padiglia Paolo Zucca Faustina B. Cannea Andrea Diana Cristina Maxia Daniela Murtas Antonio Rescigno Polyphenol oxidase (PPO, E.C. 1.14.18.1) is a nearly ubiquitous enzyme that is widely distributed among organisms. Despite its widespread distribution, the role of PPO in plants has not been thoroughly...
Plants, Vol. 9, Pages 962: Arbuscular Mycorrhizal Symbiosis Enhances Photosynthesis in the Medicinal Herb Salvia fruticosa by Improving Photosystem II Photochemistry Plants doi: 10.3390/plants9080962 Authors: Michael Moustakas Gülriz Bayçu Ilektra Sperdouli Hilal Eroğlu Eleftherios P. Eleftheriou We investigated the influence of Salvia fruticosa colonization by the arbuscular mycorrhizal fungi (AMF) Rhizophagus irregularis on photosynthetic function by using chlorophyll fluorescence...
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