Publication date: November 2020Source: Clinical Neurology and Neurosurgery, Volume 198Author(s): David J Altschul, Santiago R Unda, Rafael de La Garza Ramos, Richard Zampolin, Joshua Benton, Ryan Holland, Adisson Fortunel, Neil Haranhalli
Publication date: November 2020Source: Clinical Neurology and Neurosurgery, Volume 198Author(s): S. Bonifazi, C. Passamonti, S. Vecchioni, R. Trignani, P.P. Martorano, V. Durazzi, S. Lattanzi, F. Mancini, R.A. Ricciuti
Publication date: October 2020Source: Clinical Neurology and Neurosurgery, Volume 197Author(s): Anant Mehrotra, Suyash Singh, Soumen Kanjilal, Lili Pal, Vimal K. Paliwal, Jayesh Sardhara, Pawan K. Verma, Ved P. Maurya, Kamlesh S. Bhaisora, Kuntal K. Das, Arun K. Srivastava, Awadhesh K. Jaiswal, Sanjay Behari
Publication date: Available online 29 July 2020Source: Clinical Neurology and NeurosurgeryAuthor(s): Serap Zengin Karahan, Cavit Boz, Murat Terzi, Gonulden Aktoz, Sedat Sen, Bilge Ozbudun, Aleyna Caglar, Murat Şener
Publication date: Available online 29 July 2020Source: Clinical Neurology and NeurosurgeryAuthor(s): Adina Stan, Nicoleta Gherghel, Dafin F. Muresanu
Publication date: Available online 29 July 2020Source: Clinical Neurology and NeurosurgeryAuthor(s): Kaijia Yu, Zhiwei Ren, Song Guo, Jianyu Li, Yongjie Li
Publication date: Available online 29 July 2020Source: Clinical Neurology and NeurosurgeryAuthor(s): Xianggan Wang, Haixia Xing, Jing Cai, Dianshi Jin, Yongchun Chen, Yudi Cui, Shenghao Ding, Jieqing Wan, Yaohua Pan, Guohua Mao, Bing Zhao
Publication date: Available online 28 July 2020Source: Clinical Neurology and NeurosurgeryAuthor(s): Sean Rong-Wen Beh, Shekinah Chandy, Faiza Nazir, Umar Farooq, Aimun A.B. Jamjoom, Keith Buchan, Mahmoud Kamel
Publication date: Available online 26 July 2020Source: Clinical Neurology and NeurosurgeryAuthor(s): Evelynn Vergauwen, Christine Steiert, Marie Therese Krüger, Cordula Jilg, Stefan Zschiedrich, Jan-Helge Klingler, Vera Van Velthoven, Sven Gläsker
Publication date: Available online 25 July 2020Source: Clinical Neurology and NeurosurgeryAuthor(s): Onur Celik, Burak Ulkumen, Gorkem Eskiizmir, Fatma Can, Yüksel Pabuscu, Ugur Kamiloglu, Gokce Tanyeri Toker, Nuran Vidin
Publication date: Available online 24 July 2020Source: Clinical Neurology and NeurosurgeryAuthor(s): Giuseppe Maria Della Pepa, Giuseppe Grazia Menna, Tamara Ius, Rina Di Bonaventura, Roberto Altieri, Enrico Marchese, Alessandro Olivi, Giovanni Sabatino, Giuseppe La Rocca
Publication date: Available online 24 July 2020Source: Clinical Neurology and NeurosurgeryAuthor(s): Ahmet Ertas, Tolga Gediz, Cagatay Ozdol, Ilke Ali Gurses, Merve Onder, Mehmet Uzel, Kamran Aghayev
Publication date: Available online 24 July 2020Source: Clinical Neurology and NeurosurgeryAuthor(s): Benedikt W. Burkhardt, Akos Csokonay, Joachim M. Oertel
Publication date: Available online 23 July 2020Source: Clinical Neurology and NeurosurgeryAuthor(s): Taofiq D. Sanusi, Michael McLarnon, Ashraf Abouharb
Publication date: Available online 17 July 2020Source: Clinical Neurology and NeurosurgeryAuthor(s): Hirohisa Yajima, Hideaki Kanaya, Masahiro Ogino, Keisuke Ueki, Phyo Kim
Publication date: Available online 10 July 2020Source: Clinical Neurology and NeurosurgeryAuthor(s): Loulwah Mukharesh, Ted L. Rothstein
Publication date: Available online 24 June 2020Source: Clinical Neurology and NeurosurgeryAuthor(s): Ariane Lewis, Elana Kreiger-Benson, Andrew Kumpfbeck, Jordan Liebman, Azza Bakkar, Sam D. Shemie, Gene Sung, Sylvia Torrance, David Greer
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Abstract Purpose of Review Space-occupying lesions represent a diagnostic challenge among people with the human immunodeficiency virus, acquired immunodeficiency syndrome (HIV/AIDS). To determine the best diagnostic approach to the wide array of possible etiologies and provide a thorough interpretation of neuroimaging in order to narrow a hierarchical differential diagnosis among these patients. Given that there is no pathognomonic...
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Abstract Regional alterations in kinetics of catecholamine uptake are due in part to variations in clearance mechanisms. The rate of clearance is a critical determinant of the strength of catecholamine signaling. Catecholamine transmission in the nucleus accumbens core (NAcc) and basolateral amygdala (BLA) is of particular interest due to involvement of these regions in cognition and motivation. Previous work has shown that catecholamine clearance in the NAcc is largely mediated by the dopamine...
Abstract Asynchrony is a critical cue informing the brain whether sensory signals are caused by a common source and should be integrated or segregated. This psychophysics‐electroencephalography (EEG) study investigated the influence of asynchrony on how the brain binds audiotactile (AT) signals to enable faster responses in a redundant target paradigm. Human participants actively responded (psychophysics) or passively attended (EEG) to noise bursts, ‘taps‐to‐the‐face’, and their AT combinations...
Abstract Combined antiretroviral therapy for HIV infection reduces plasma viral load and prolongs life. However, the brain is a viral reservoir, and pathologies such as cognitive decline and blood‐brain barrier (BBB) disruption persist. Methamphetamine abuse is prevalent among HIV‐infected individuals. Methamphetamine and HIV toxic proteins can disrupt the BBB, but it is unclear if there exists a common pathway by which HIV proteins and methamphetamine induce BBB damage. Also unknown are the BBB...
Abstract One of the key knowledge gaps in the field of Alzheimer’s disease research is the lack of understanding of how amyloid beta and tau cooperate to cause neurodegeneration. We recently generated a mouse model (APP/PS1+Tau) that develops amyloid plaque pathology and expresses human tau in the absence of endogenous murine tau. These mice exhibit an age‐related behavioural hyperactivity phenotype and transcriptional deficits which are ameliorated by tau transgene suppression. We hypothesized...
Abstract We investigated long‐term environmental influences on morphology of microglia from the outer and middle thirds of molecular layer of the dentate gyrus (MolDG), and on microglia from dorsal and ventral dentate gyrus molecular layer. We also estimated the total number of MolDG microglia using stereology. For this purpose, microglia of the molecular layer of the dentate gyrus of 20 month old female Swiss albino mice, housed from 21st postnatal day onwards, in the impoverished environment of...
Abstract Non‐invasive brain stimulation has been of interest as a therapeutic tool to modulate cortical excitability. However, there is little evidence that oscillatory brain stimulation can modulate the cortical control of muscle activities during gait, which can be assessed using coherence analysis of paired surface electromyographic (EMG) recordings. This study aimed to investigate the effects of gait‐combined transcranial alternating current stimulation (tACS) at the gait cycle frequency on...
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Abstract It has been proposed that the maintenance of phonological information in verbal working memory (vWM) is carried by a domain-specific short-term storage center—the phonological loop—which is composed of a phonological store and an articulatory rehearsal system. Several brain regions including the left posterior inferior frontal gyrus (pIFG) and anterior supramarginal gyri (aSMG) are thought to support these processes. However, recent behavioral evidence suggests that verbal...
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Publication date: Available online 30 July 2020Source: Journal of Neuroscience MethodsAuthor(s): Hiromi Sano, Kenta Kobayashi, Nozomu Yoshioka, Hirohide Takebayashi, Atsushi Nambu
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BACKGROUND AND PURPOSE:Tractography of the facial nerve based on single-shell diffusion MR imaging is thought to be helpful before surgery for resection of vestibular schwannoma. However, this paradigm can be vitiated by the isotropic diffusion of the CSF, the convoluted path of the facial nerve, and its crossing with other bundles. Here we propose a multishell diffusion MR imaging acquisition scheme combined with probabilistic tractography that has the potential to provide a presurgical facial nerve...
SUMMARY:Fueled by new techniques, computational tools, and broader availability of imaging data, artificial intelligence has the potential to transform the practice of neuroradiology. The recent exponential increase in publications related to artificial intelligence and the central focus on artificial intelligence at recent professional and scientific radiology meetings underscores the importance. There is growing momentum behind leveraging artificial intelligence techniques to improve workflow and...
BACKGROUND AND PURPOSE:Inflammatory changes in the fat tissue surrounding the coronary arteries have been associated with coronary artery disease and high-risk vulnerable plaques. Our aim was to investigate possible correlations between the presence and degree of perivascular fat density and a marker of vulnerable carotid plaque, namely contrast plaque enhancement on CTA.MATERIALS AND METHODS:One-hundred patients (76 men, 24 women; mean age, 69 years) who underwent CT angiography for investigation...
BACKGROUND AND PURPOSE:Volumetric brain MR imaging typically has long acquisition times. We sought to evaluate an ultrafast MPRAGE sequence based on Wave-CAIPI (Wave-MPRAGE) compared with standard MPRAGE for evaluation of regional brain tissue volumes.MATERIALS AND METHODS:We performed scan-rescan experiments in 10 healthy volunteers to evaluate the intraindividual variability of the brain volumes measured using the standard and Wave-MPRAGE sequences. We then evaluated 43 consecutive patients undergoing...
BACKGROUND AND PURPOSE:Cerebral MR imaging in infants is usually performed with a field strength of up to 3T. In adults, a growing number of studies have shown added diagnostic value of 7T MR imaging. 7T MR imaging might be of additional value in infants with unexplained seizures, for example. The aim of this study was to investigate the feasibility of 7T MR imaging in infants. We provide information about the safety preparations and show the first MR images of infants at 7T.MATERIALS AND METHODS:Specific...
BACKGROUND AND PURPOSE:The incidence of oropharyngeal squamous cell carcinoma (OPSCC) has increased in the period from the 1970s to 2004, due to increase of infection with human papilloma virus (HPV). This study aimed to examine the role of histogram analysis of the ADC in treatment response and survival prediction of patients with oropharyngeal squamous cell carcinoma and known human papillomavirus status.MATERIALS AND METHODS:This was a retrospective single-center study. Following inclusion and...
BACKGROUND:In-stent restenosis affects long-term outcome in patients with intracranial atherosclerotic stenosis.PURPOSE:The aim of this meta-analysis was to evaluate the incidence and risk factors of in-stent restenosis.DATA SOURCES:All literature that reported in-stent restenosis was searched on PubMed, Ovid EMBASE and Ovid MEDLINE data bases.STUDY SELECTION:Original articles about stents for symptomatic intracranial atherosclerotic stenosis were selected.DATA ANALYSIS:Meta-analysis was conducted...
BACKGROUND AND PURPOSE:Increased contrast enhancement has been used as a marker of malignant transformation in low-grade gliomas. This marker has been found to have limited accuracy because many low-grade gliomas with increased contrast enhancement remain grade II. We aimed to investigate whether MR spectroscopy can contribute to the diagnosis of malignant transformation in low-grade gliomas with increased contrast enhancement.MATERIALS AND METHODS:Patients with low-grade gliomas who had contemporaneous...
SUMMARY:Neurologic findings are being increasingly recognized in coronavirus disease 2019. We present a patient with a unique involvement of the corpus callosum that we relate to the cytokine storm seen in patients with Severe Acute Respiratory Syndrome coronavirus 2 infection. As the infection is increasingly seen around the world, recognition of these unique patterns may facilitate early identification of the progression of this disease and potentially facilitate appropriate management.
SUMMARY:Since December 2019, a novel Severe Acute Respiratory Syndrome coronavirus 2 from China has rapidly spread worldwide. Although respiratory involvement is the mainstay of coronavirus disease 2019 (COVID-19), systemic involvement has recently drawn more attention. In particular, a number of recent articles have shed light on the nervous system as one of the possible targets. At our institution, we observed 15 patients with acute brain vascular manifestations; most interesting, we had a higher...
BACKGROUND AND PURPOSE:After endovascular treatment of intracranial aneurysms with the Woven EndoBridge (WEB) device, worsening of aneurysm occlusion or re-opening was reported to be possibly associated with WEB shape modification. This study analyzed quantitatively the WEB shape modification with time in association with anatomic results.MATERIALS AND METHODS:Thirty patients with 32 WEB-treated intracranial aneurysms fulfilled the inclusion criteria of cranial CT at baseline (day of intervention)...
BACKGROUND AND PURPOSE:Polymicrogyria and lissencephaly may be associated with abnormal organization of the undelying white matter tracts that have been rarely investigated so far. Our aim was to characterize white matter tract organization in polymicrogyria and lissencephaly using constrained spherical deconvolution, a multifiber diffusion MR imaging modeling technique for white matter tractography reconstruction.MATERIALS AND METHODS:We retrospectively reviewed 50 patients (mean age, 8.3 ± 5.4...
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When different senses are in conflict, one sense may dominate the perception of other sense, but it is not known whether the sensory cortex associated with the dominant modality exerts directional influence, at the functional brain level, over the sensory cortex associated with the dominated modality; in short, the link between sensory dominance and neuronal dominance is not established. In a task involving audio-visual conflict, using magnetoencephalography recordings in humans, we first demonstrated...
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Publication date: October 2020Source: World Neurosurgery, Volume 142Author(s): Oguz Karaeminogullari, Ozgur Ozer
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