Dimah AlAskar, Mais AlSardi, Eman Al Sulais, Mahmoud Mosli, Turki AlAmeelSaudi Journal of Gastroenterology 2020 26(4):210-215 Background/Aim: Tumor necrosis factor inhibitors (TNFi) have become the mainstay of treatment in moderate-to-severe cases of inflammatory bowel disease (IBD). Neutropenia has been reported in patients receiving TNFi for IBD and other diseases. In this study, we aimed to ascertain the relationship between the use of TNFi and the development of neutropenia in patients with...
Yuexiang Niu, Gongen Tang, Xiuli Wu, Chaoyu WuSaudi Journal of Gastroenterology 2020 26(4):194-203 Background/Aims: The purpose of this study is to explore the expression characteristics of lncRNA NEAT1 in hepatocellular carcinoma (HCC) and the molecular mechanism of its regulation on sorafenib resistance. Materials and Methods: This experimental study was performed from June 2013 to June 2019. The level of NEAT1 was determined using RT-PCR in HCC and matched adjacent tissues from 79 HCC patients...
Jie Tan, Jian Zhang, Zhenzhen Zhao, Jie Zhang, Mengzhen Dong, Xuefeng Ma, Shousheng Liu, Yongning XinSaudi Journal of Gastroenterology 2020 26(4):171-178 Background/Aims: The role of two polymorphisms rs1800591 and rs3816873 of the microsomal triglyceride transfer protein (MTTP) gene in the development of nonalcoholic fatty liver disease (NAFLD) remains controversial. A meta-analysis was conducted to determine the correlation between these MTTP polymorphisms and NAFLD. Materials and Methods:...
Hani LababidiSaudi Journal of Gastroenterology 2020 26(4):169-170
Nahla Azzam, Nehal Khamis, Majid Almadi, Faisal Batwa, Fahad Alsohaibani, Abdulrahman Aljebreen, Ahmad Alharbi, Yasser Alaska, Turki Alameel, Peter Irving, Richard M SatavaSaudi Journal of Gastroenterology 2020 26(4):179-187 Background/Aims: This study aimed to design a structured simulation training curriculum for upper endoscopy and validate a new assessment checklist. Materials and Methods: A proficiency-based progression stepwise curriculum was developed consisting of didactic, technical...
Faisal A Alsaif, Sara H Alqahtani, Amani M Alsadoon, Khalid A Alswat, Ayman A Abdo, Mazen M Hassanain, Abdulsalam B Alsharabi, Ghadeer R Aljuhani, Hisham M Alkhalidi, Mohammad S Elsharkawy, Maram A Alotaibi, Faisal M Sanai, Waleed K Al-hamoudiSaudi Journal of Gastroenterology 2020 26(4):204-209 Background/Aim: Gallstone disease (GD) and nonalcoholic fatty liver disease (NAFLD) are associated with metabolic syndrome. Despite the benign nature of NAFLD, 10% of patients may develop advanced fibrosis...
Murad Aljiffry, Mohammad Abbas, Mohammad A. M. Wazzan, Ahmed H Abduljabbar, Safiyah Aloufi, Emad AljahdliSaudi Journal of Gastroenterology 2020 26(4):188-193 Background/Aim: Biliary tree and pancreatic duct can appear in different variations whose proper understanding is obligatory for surgeons. Magnetic resonance cholangiopancreatography (MRCP) is considered a safe and accurate tool for evaluating biliary tree and pancreatic duct. Typical anatomy for right hepatic duct (RHD) and left hepatic...
Mohamad Mubder, Banreet Dhindsa, Danny Nguyen, Syed Saghir, Chad Cross, Ranjit Makar, Gordon OhningSaudi Journal of Gastroenterology 2020 26(4):216-221 Background/Aim: Acute pancreatitis (AP) is a commonly encountered emergency where early identification of complicated cases is important. Inflammatory markers like lymphocyte to monocyte ratio (LMR) and neutrophil to lymphocyte ratio (NLR) are simple and readily available markers. In this study, we evaluated the utility of these markers in the...
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