Δευτέρα 23 Μαρτίου 2020


Electronic direct-to-consumer advertising of pharmaceuticals: an assessment of textual and visual content of websites
AbstractConsidering the important role of the Internet in health information seeking by consumers, it is critical to examine the health information that is available to them through the Internet. This study contributes to existing knowledge by employing a content analysis to examine visual and textual information on prescription medication websites. A stratified random sample was selected from a list of the 100 most-prescribed medications in the United States. Findings point to under-utilization...
Health Education Research
10h
Resilience-based alcohol education: developing an intervention, evaluating feasibility and barriers to implementation using mixed-methods
AbstractAlcohol education must ensure that young people have appropriate information, motivation and skills. This article describes the fifth phase in a program of intervention development based on principles of social marketing and intervention mapping. The aim was to enhance drink refusal self-efficacy (DRSE) and help develop skills for non-drinking or moderate drinking. We conducted a mixed-methods feasibility trial that measured intervention effects among 277 UK secondary school students aged...
Health Education Research
10h
A decade of sun protection in Australian early-childhood services: analysis of cross-sectional and repeated-measures data
AbstractLimiting ultraviolet radiation exposure during early childhood can significantly reduce the risk of developing skin cancer, making early childhood a critical time for sun protection strategies. This study aimed to measure sun protection practices utilized in Australian early-childhood services over the past decade and evaluate the impact of Cancer Council Australia’s SunSmart Early-Childhood Program. Results are presented from cross-sectional and repeated-measures survey data, completed by...
Health Education Research
10h
The omental free flap and flow-through flap: pre-operative evaluation of right gastro-omental artery on multidetector computed tomography
Abstract Background The gastro-omental artery (GOA) and the greater omentum are nowadays commonly used in many reconstructive surgeries, including cardiac, vascular, and plastic surgery. There are cases in which the GOA is found to be unsuitable only after partial harvesting following an upper laparotomy, and an improved method of pre-operative evaluation is required to eliminate the need for intraoperative small laparotomy. ...
Latest Results for Abdominal Imaging
10h
Endometriosis in pregnancy
Abstract Endometriosis constitutes the presence of ectopic endometrial glands and stroma outside the uterine endometrium, which is hormonally responsive and responds to pregnancy hormones as well. Decidualization is a physiologic process, where the normal endometrium readies itself for optimal accommodation of a pregnancy. A similar hormonal response can be seen with ectopic endometrium as well. As such, ovarian endometriomas and deep endometriosis implants can undergo decidualization....
Latest Results for Abdominal Imaging
16h
Pharmacists and assisted dying
The UN General Assembly has emphasised that the right to freedom of thought, conscience, and religion or belief applies equally to all people, regardless of their religion or belief and without any...
Latest headlines from BMJ
10h
Pharmacists and assisted dying
The UN General Assembly has emphasised that the right to freedom of thought, conscience, and religion or belief applies equally to all people, regardless of their religion or belief and without any...
Latest headlines from BMJ
11h
New York is centre of US epidemic as Trump pitches in to help
President Donald Trump said he was activating the National Guard to help the three states hit hardest by covid-19.New York State has more than 15 000 cases: 10 764 in the city and many others in its...
Latest headlines from BMJ
12h
Assisted dying: doctors should maintain their role as healers
I agree with Heath and Hartling that the emotional impact and societal message of physician assisted dying needs to be considered in the context of a society that does not value older age and wisdom...
Latest headlines from BMJ
12h
New York is centre of US epidemic as Trump pitches in to help
President Donald Trump said he was activating the National Guard to help the three states hit hardest by covid-19.New York State has more than 15 000 cases: 10 764 in the city and many others in its...
Latest headlines from BMJ
14h
Assisted dying: doctors should maintain their role as healers
I agree with Heath and Hartling that the emotional impact and societal message of physician assisted dying needs to be considered in the context of a society that does not value older age and wisdom...
Latest headlines from BMJ
15h
Covid-19: doctors in final trimester of pregnancy should avoid direct patient contact
Women who are more than 28 weeks pregnant should avoid direct contact with patients—whether or not they could be infected with covid-19, says updated guidance. Those who are less than 28 weeks...
Latest headlines from BMJ
15h
WHO must prioritise the needs of older people in its response to the covid-19 pandemic
The World Health Organization is the most influential global body guiding responses to the covid-19 pandemic. It is working around the clock to issue helpful guidance for technical experts and the...
Latest headlines from BMJ
15h
Clinical trials suspended in UK to prioritise covid-19 studies and free up staff
New clinical trials are being suspended to prioritise covid-19 studies and enable the redeployment of clinical staff to frontline care, the National Institute for Health Research (NIHR) has...
Latest headlines from BMJ
15h
Covid-19: Highest risk patients are asked to stay at home for 12 weeks
A million and a half people in England who are at very high risk of severe illness and admission to hospital because of covid-12 will receive a letter this week asking them to stay at home for at...
Latest headlines from BMJ
15h
Covid-19: give NHS staff rest spaces and free parking not thank yous, says doctor
An NHS consultant has called for NHS staff working during the covid-19 pandemic to be rewarded with rest areas and free parking.Speaking to LBC radio on 19 March the intensive care consultant known...
Latest headlines from BMJ
15h
Online patient feedback is positive, but not used effectively
The studyPowell J, Atherton H, Williams V, et al. Using online patient feedback to improve NHS services: the INQUIRE multimethod study. Health Serv Deliv Res 2019;7:38.This project was funded by the...
Latest headlines from BMJ
15h
Covid-19: doctors in final trimester of pregnancy should avoid direct patient contact
Women who are more than 28 weeks pregnant should avoid direct contact with patients—whether or not they could be infected with covid-19, says updated guidance. Those who are less than 28 weeks...
Latest headlines from BMJ
16h
WHO must prioritise the needs of older people in its response to the covid-19 pandemic
The World Health Organization is the most influential global body guiding responses to the covid-19 pandemic. It is working around the clock to issue helpful guidance for technical experts and the...
Latest headlines from BMJ
17h
Clinical trials suspended in UK to prioritise covid-19 studies and free up staff
New clinical trials are being suspended to prioritise covid-19 studies and enable the redeployment of clinical staff to frontline care, the National Institute for Health Research (NIHR) has...
Latest headlines from BMJ
17h
Covid-19: Highest risk patients are asked to stay at home for 12 weeks
A million and a half people in England who are at very high risk of severe illness and admission to hospital because of covid-12 will receive a letter this week asking them to stay at home for at...
Latest headlines from BMJ
17h
Covid-19: give NHS staff rest spaces and free parking not thank yous, says doctor
An NHS consultant has called for NHS staff working during the covid-19 pandemic to be rewarded with rest areas and free parking.Speaking to LBC radio on 19 March the intensive care consultant known...
Latest headlines from BMJ
17h
Covid-19: US testing ramps up as early response draws harsh criticism
Daily testing for coronavirus infection in the United States is finally approaching levels seen in other developed countries. This follows nearly two months in which tests were difficult to obtain...
Latest headlines from BMJ
18h
Sixty seconds on . . . covid kindness
Kindness?! We have more pressing needs than that!Yes, you do. But this column is going to focus on the nice things that people are offering to do for NHS staff during this time.Okay, like what?Well,...
Latest headlines from BMJ
18h
Covid-19: European drugs agency to review safety of ibuprofen
Debate over the safety of non-steroidal anti-inflammatory drugs (NSAIDs) in treating covid-19 has continued with the European Medicines Agency saying that the drugs could be considered for treating...
Latest headlines from BMJ
18h
US gun violence and deaths
The crisis of gun violence in the United States continues unabated. In 2018, of 39 740 firearm deaths, 24 432 were suicides (roughly half of all suicides) and 13 958 were homicides, with Mississippi,...
Latest headlines from BMJ
19h
Covid-19: identifying and isolating asymptomatic people helped eliminate virus in Italian village
An Italian academic has claimed striking evidence that most people infected with covid-19 show no symptoms but are still able to infect others, which he says has huge implications for testing policy,...
Latest headlines from BMJ
19h
Role model: Alex Ball
Alex Ball, consultant and clinical lead in rehabilitation medicine at Haywood Hospital, Stoke-on-Trent, is a passionate teacher who finds tailored solutions to patients’ problems.She qualified from...
Latest headlines from BMJ
19h
The BMJ should advocate for the care of all dying people
The BMJ says that it “has long advocated for a change in the law in assisted dying.”1 How much time has the editorial team dedicated to advocating for the care of all dying people? Looking back, how...
Latest headlines from BMJ
19h
Covid-19: six million doses of hydroxychloroquine donated to US despite lack of evidence
Drug company Teva has said that it will donate more than six million doses of hydroxychloroquine sulfate tablets to hospitals across the US, to “meet the urgent demand for the medicine as an...
Latest headlines from BMJ
19h
Online patient feedback is positive, but not used effectively
The studyPowell J, Atherton H, Williams V, et al. Using online patient feedback to improve NHS services: the INQUIRE multimethod study. Health Serv Deliv Res 2019;7:38.This project was funded by the...
Latest headlines from BMJ
19h
Life as a doctor in the Royal Navy
Life as a doctor in the Royal Navy is incredibly varied and no two days are the same. You could be working on shore providing daily GP care to your colleagues or be the only doctor on board a ship...
Latest headlines from BMJ
19h
DEqMS: a method for accurate variance estimation in differential protein expression analysis [Technological Innovation and Resources]
Quantitative proteomics by mass spectrometry is widely used in biomarker research and basic biology research for investigation of phenotype level cellular events. Despite the wide application, the methodology for statistical analysis of differentially expressed proteins has not been unified. Various methods such as t-test, linear model and mixed effect models are used to define changes in proteomics experiments. However, none of these methods consider the specific structure of MS-data. Choices between...
MCP Papers in Press
10h
Delivery of Antisense Oligonucleotides to the Cornea
Nucleic Acid Therapeutics, Ahead of Print.
Nucleic Acid Therapeutics - Table of Contents
10h
Reverse Transcription Quantitative Polymerase Chain Reaction Methods to Support Pharmacokinetics and Drug Mechanism of Action to Advance Development of RNA Interference Therapeutics
Nucleic Acid Therapeutics, Ahead of Print.
Nucleic Acid Therapeutics - Table of Contents
10h
Malignancy Rates in Brodalumab Clinical Studies for Psoriasis
Abstract Background Brodalumab is a fully human anti–interleukin-17 receptor A monoclonal antibody efficacious for the treatment of adults with moderate-to-severe plaque psoriasis. Objective This study summarizes malignancy rates in psoriasis clinical studies of brodalumab. Methods ...
Latest Results for American Journal of Clinical Dermatology
10h
Rsph4a is essential for the triplet radial spoke head assembly of the mouse motile cilia
by Hiroshi Yoke, Hironori Ueno, Akihiro Narita, Takafumi Sakai, Kahoru Horiuchi, Chikako Shingyoji, Hiroshi Hamada, Kyosuke Shinohara Motile cilia/flagella are essential for swimming and generating extracellular fluid flow in eukaryotes. Motile cilia harbor a 9+2 arrangement consisting of nine doublet microtubules with dynein arms at the periphery and a pair of singlet microtubules at the center (central pair). In the central system, the radial spoke has a T-shaped architecture and regulates...
PLOS Genetics: New Articles
11h
Light affects tissue patterning of the hypocotyl in the shade-avoidance response
by Esther Botterweg-Paredes, Anko Blaakmeer, Shin-Young Hong, Bin Sun, Lorenzo Mineri, Valdeko Kruusvee, Yakun Xie, Daniel Straub, Delphine Ménard, Edouard Pesquet, Stephan Wenkel Plants have evolved strategies to avoid shade and optimize the capture of sunlight. While some species are tolerant to shade, plants such as Arabidopsis thaliana are shade-intolerant and induce elongation of their hypocotyl to outcompete neighboring plants. We report the identification of a developmental module acting...
PLOS Genetics: New Articles
11h
Pericentromeric heterochromatin is hierarchically organized and spatially contacts H3K9me2 islands in euchromatin
by Yuh Chwen G. Lee, Yuki Ogiyama, Nuno M. C. Martins, Brian J. Beliveau, David Acevedo, C.-ting Wu, Giacomo Cavalli, Gary H. Karpen Membraneless pericentromeric heterochromatin (PCH) domains play vital roles in chromosome dynamics and genome stability. However, our current understanding of 3D genome organization does not include PCH domains because of technical challenges associated with repetitive sequences enriched in PCH genomic regions. We investigated the 3D architecture of Drosophila...
PLOS Genetics: New Articles
11h

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