Publication date: Available online 23 March 2020Source: NeuroImageAuthor(s): Christina M. Vanden Bosch der Nederlanden, Marc Joanisse, Jessica A. Grahn
Mon Mar 23, 2020 13:55
Publication date: Available online 22 March 2020Source: NeuroImageAuthor(s): Nerissa Siu Ping Ho, Giulia Poerio, Delali Konu, Adam Turnbull, Mladen Sormaz, Robert Leech, Boris Bernhardt, Elizabeth Jefferies, Jonathan Smallwood
Mon Mar 23, 2020 13:55
Nature Communications, Published online: 23 March 2020; doi:10.1038/s41467-020-15183-2Chromatin remodellers hydrolyse ATP to move nucleosomal DNA against histone octamers. Here, the authors use single-molecule assays to examine the mechanism of action of CHD4 remodeller, and provide evidence that CHD4 slides nucleosomes by decoupling entry- and exit-side DNA translocation.
Mon Mar 23, 2020 02:00
Nature Communications, Published online: 23 March 2020; doi:10.1038/s41467-020-15340-7Knowing compositional motifs of nanoparticle catalysts in operando conditions is crucial towards understanding their catalytic behavior. Here, the authors develop a physics-driven machine learning approach to predict adsorption sites for a CO molecule over platinum nanoparticles in a multitude of coordination environments.
Mon Mar 23, 2020 02:00
Nature Communications, Published online: 23 March 2020; doi:10.1038/s41467-020-15253-5Ferromagnetic quasi-atomic behavior of interstitial anionic electrons (IAEs) in practical electrides is yet to be discovered experimentally. Here, the authors reveal that IAEs in two-dimensional electride [Gd2C]²+⋅2e- behave as magnetic elements with their own magnetic moment.
Mon Mar 23, 2020 02:00
Nature Communications, Published online: 23 March 2020; doi:10.1038/s41467-020-14918-5Whole-cell catalyst-based hydroxytyrosol production is low. Here, the authors increase the efficiency of its production in E. coli by de-bottlenecking two enzymatic steps catalyzed by monooxygenase and tyramine oxidase using structure-based enzyme redesign or in vivo-directed evolution with the aid of a newly developed biosensor.
Mon Mar 23, 2020 02:00
Nature Communications, Published online: 23 March 2020; doi:10.1038/s41467-020-15272-2Inteins allow the joining of protein segments through scarless ligation. Here the authors assess 34 inteins to establish a library of 15 mutually orthogonal split inteins for in vivo applications, 10 of which are also active in vitro.
Mon Mar 23, 2020 02:00
Nature Communications, Published online: 23 March 2020; doi:10.1038/s41467-020-15098-yPublisher Correction: Single-cell RNA-sequencing of differentiating iPS cells reveals dynamic genetic effects on gene expression
Mon Mar 23, 2020 02:00
Nature Communications, Published online: 23 March 2020; doi:10.1038/s41467-020-15329-2Cryptococcus neoformans causes fatal fungal meningoencephalitis. Here, the authors identify fungal kinases and transcription factors involved in blood-brain barrier crossing and brain infection in mice.
Mon Mar 23, 2020 02:00
Nature Communications, Published online: 23 March 2020; doi:10.1038/s41467-020-15268-yAcyl-acyl carrier protein reductase (AAR) and aldehyde deformylating oxygenase (ADO) are the two enzymes in a cyanobacterial alkane biosynthesis pathway that is of interest for biofuel production. Here the authors provide insights into the catalytic mechanisms of AAR and the coupling between the two enzymes by determining the crystal structures of AAR alone and three AAR–ADO complexes with various bound ligands.
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