JCM, Vol. 9, Pages 879: Kidney Perfusion as an Organ Quality Assessment Tool—Are We Counting Our Chickens Before They Have Hatched? Journal of Clinical Medicine doi: 10.3390/jcm9030879 Authors: De Beule Jochmans The final decision to accept an organ for transplantation remains a subjective one. With “poor organ quality” commonly cited as a major reason for kidney discard, accurate, objective, and reliable quality assessment is essential. In an era of increasingly...
JCM, Vol. 9, Pages 880: Special Issue: Sleep Bruxism—The Controversial Sleep Movement Activity Journal of Clinical Medicine doi: 10.3390/jcm9030880 Authors: Wieckiewicz Winocur According to the current approach [1], bruxism is considered as two different behaviours observed during sleep and wakefulness, respectively, and the single definition for bruxism has been replaced by two separate definitions [...]
JCM, Vol. 9, Pages 878: Natural History of Arrhythmogenic Cardiomyopathy Journal of Clinical Medicine doi: 10.3390/jcm9030878 Authors: Mattesi Zorzi Corrado Cipriani Arrhythmogenic cardiomyopathy (AC) is a heart muscle disease characterized by a scarred ventricular myocardium with a distinctive propensity to ventricular arrhythmias (VAs) and sudden cardiac death, especially in young athletes. Arrhythmogenic right ventricular cardiomyopathy (ARVC) represents the best characterized...
JCM, Vol. 9, Pages 877: The Influence of CD28 Gene Polymorphism in Transfusion Reaction after Transfusing Leukoreduced Blood Components Journal of Clinical Medicine doi: 10.3390/jcm9030877 Authors: Chen Lin Wang Chiueh CTLA-4 and CD28 belong to co-stimulation molecules, the abnormal expression of which can regulate the T cell activation and then affect the degree of immune response. Moreover, blood transfusion reaction (TR) is a kind of immune reaction. Consequently, the...
JCM, Vol. 9, Pages 876: Damage-Associated Molecular Patterns and Th-Cell-Related Cytokines Released after Progressive Effort Journal of Clinical Medicine doi: 10.3390/jcm9030876 Authors: Dorota Kostrzewa-Nowak Andrzej Ciechanowicz Jeremy S.C. Clark Robert Nowak Inflammation-induced processes commence with the activation of signalling pathways at the cellular level, which mobilize inflammatory cells and stimulate the secretion of chemokines, cytokines, and damage-associated molecular...
JCM, Vol. 9, Pages 875: Development and Validation of a Quick Sepsis-Related Organ Failure Assessment-Based Machine-Learning Model for Mortality Prediction in Patients with Suspected Infection in the Emergency Department Journal of Clinical Medicine doi: 10.3390/jcm9030875 Authors: Kwon Baek The quick sepsis-related organ failure assessment (qSOFA) score has been introduced to predict the likelihood of organ dysfunction in patients with suspected infection. We hypothesized that...
JCM, Vol. 9, Pages 874: Assessment of the Short-Term Effects after High-Inductive Electromagnetic Stimulation of Pelvic Floor Muscles: A Randomized, Sham-Controlled Study Journal of Clinical Medicine doi: 10.3390/jcm9030874 Authors: Ptaszkowski Malkiewicz Zdrojowy Ptaszkowska Paprocka-Borowicz Background: Physiotherapy should be performed by patients with stress or mixed urinary incontinence (SUI and MUI) to increase the strength and endurance of the pelvic floor muscles...
JCM, Vol. 9, Pages 873: Factorial Structure and Validity of Depression (PHQ-9) and Anxiety (GAD-7) Scales after Traumatic Brain Injury Journal of Clinical Medicine doi: 10.3390/jcm9030873 Authors: Ali Teymoori Anastasia Gorbunova Fardzadeh E. Haghish Ruben Real Marina Zeldovich Yi-Jhen Wu Suzanne Polinder Thomas Asendorf David Menon CENTER-TBI Investigators and Participants CENTER-TBI Investigators and Participants Nicole v. Steinbüchel Background: The dimensionality...
JCM, Vol. 9, Pages 872: Early Post-Stroke Infections Are Associated with an Impaired Function of Neutrophil Granulocytes Journal of Clinical Medicine doi: 10.3390/jcm9030872 Authors: van Gemmeren Schuppner Grosse Fering Gabriel Huber Worthmann Lichtinghagen Weissenborn To investigate whether neutrophil granulocytes’ function relates to post-stroke infections and clinical outcome after stroke, we prospectively recruited 95 patients after ischemic...
JCM, Vol. 9, Pages 871: Artificial Intelligence-Based Diagnosis of Cardiac and Related Diseases Journal of Clinical Medicine doi: 10.3390/jcm9030871 Authors: Arsalan Owais Mahmood Choi Park Automatic chest anatomy segmentation plays a key role in computer-aided disease diagnosis, such as for cardiomegaly, pleural effusion, emphysema, and pneumothorax. Among these diseases, cardiomegaly is considered a perilous disease, involving a high risk of sudden cardiac death. It...
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Medical Sciences, Vol. 8, Pages 18: Breast Cancer: A Molecularly Heterogenous Disease Needing Subtype-Specific Treatments Medical Sciences doi: 10.3390/medsci8010018 Authors: Testa Castelli Pelosi Breast cancer is the most commonly occurring cancer in women. There were over two-million new cases in world in 2018. It is the second leading cause of death from cancer in western countries. At the molecular level, breast cancer is a heterogeneous disease, which is characterized by...
Medical Sciences, Vol. 8, Pages 17: Introduction to “Chronic Rhinosinusitis and Concomitant Medical Disorders” Medical Sciences doi: 10.3390/medsci8010017 Authors: David A. Gudis It is with great pleasure and enthusiasm that we present to you this Special Issue of Medical Sciences [...]
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Medicina, Vol. 56, Pages 144: Amelioration of Scopolamine-Induced Amnesic, Anxiolytic and Antidepressant Effects of Ficus Benghalensis in Behavioral Experimental Models Medicina doi: 10.3390/medicina56030144 Authors: Humna Malik Sana Javaid Muhammad Fawad Rasool Noreen Samad Syed Rizwan Ahamad Faleh Alqahtani Imran Imran Background and Objectives: Ficus benghalensis (FB) is a commonly found tree in Pakistan and its various parts have folkloric importance in managing...
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Metabolites, Vol. 10, Pages 119: Extensive Profiling of Polyphenols from two Trollius Species Using a Combination of Untargeted and Targeted Approaches Metabolites doi: 10.3390/metabo10030119 Authors: Tian Zhou Shui Lam Various species of globeflowers, belonging to the genus Trollius, have been extensively used in traditional Chinese medicine due to their anti-inflammatory, antimicrobial, and antiviral properties, which are mainly attributed to their high polyphenol content....
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Microorganisms, Vol. 8, Pages 456: Fungal Microbiota of Sea Buckthorn Berries at Two Ripening Stages and Volatile Profiling of Potential Biocontrol Yeasts Microorganisms doi: 10.3390/microorganisms8030456 Authors: Juliana Lukša Iglė Vepštaitė-Monstavičė Violeta Apšegaitė Laima Blažytė-Čereškienė Ramunė Stanevičienė Živilė Strazdaitė-Žielienė Bazilė Ravoitytė Dominykas Aleknavičius Vincas Būda Raimondas Mozūraitis Elena Servienė Sea buckthorn, Hippophae rhamnoides...
Microorganisms, Vol. 8, Pages 453: Lipid Production from Sugarcane Top Hydrolysate and Crude Glycerol with Rhodosporidiobolus fluvialis using a Two-Stage Batch-Cultivation Strategy with Separate Optimization of Each Stage Microorganisms doi: 10.3390/microorganisms8030453 Authors: Boonyarit Polburee Khaenda Zhao Limtong Lipids from oleaginous microorganisms, including oleaginous yeasts, are recognized as feedstock for biodiesel production. A production process development...
Microorganisms, Vol. 8, Pages 451: Comparative Proteomics Analysis Reveals New Features of the Oxidative Stress Response in the Polyextremophilic Bacterium Deinococcus radiodurans Microorganisms doi: 10.3390/microorganisms8030451 Authors: Lihua Gao Zhengfu Zhou Xiaonan Chen Wei Zhang Min Lin Ming Chen Deinococcus radiodurans is known for its extreme resistance to ionizing radiation, oxidative stress, and other DNA-damaging agents. The robustness of this bacterium primarily...
Microorganisms, Vol. 8, Pages 454: Formate Utilization by the Crenarchaeon Desulfurococcus amylolyticus Microorganisms doi: 10.3390/microorganisms8030454 Authors: Ergal Reischl Hasibar Manoharan Zipperle Bochmann Fuchs Rittmann Formate is one of the key compounds of the microbial carbon and/or energy metabolism. It owes a significant contribution to various anaerobic syntrophic associations, and may become one of the energy storage compounds of modern energy...
Microorganisms, Vol. 8, Pages 452: Bridging the Gap: A Role for Campylobacter jejuni Biofilms Microorganisms doi: 10.3390/microorganisms8030452 Authors: Greg Tram Christopher J. Day Victoria Korolik Campylobacter jejuni is the leading cause of bacterial gastroenteritis in the developed world. Cases of Campylobacteriosis are common, as the organism is an avian commensal and is passed on to humans through contaminated poultry meat, water, and food preparation areas. Although typically...
Microorganisms, Vol. 8, Pages 450: Liver Transudate, a Potential Alternative to Detect Anti-Hepatitis E Virus Antibodies in Pigs and Wild Boars (Sus scrofa) Microorganisms doi: 10.3390/microorganisms8030450 Authors: Alejandro Navarro Carmen Bárcena Pilar Pozo Alberto Díez-Guerrier Irene Martínez Coral Polo Clara Duque David Rodríguez-Lázaro Joaquín Goyache Nerea García In recent years, cases of hepatitis E virus (HEV) infection have increased in Europe in association...
Microorganisms, Vol. 8, Pages 455: Activity of Cinnamaldehyde on Quorum Sensing and Biofilm Susceptibility to Antibiotics in Pseudomonas aeruginosa Microorganisms doi: 10.3390/microorganisms8030455 Authors: Topa Palombo Kingshott Blackall Quorum sensing (QS) plays an important role during infection for the opportunistic human pathogen Pseudomonas aeruginosa. Quorum sensing inhibition (QSI) can disrupt this initial event of infection without killing bacterial cells, and thus...
Microorganisms, Vol. 8, Pages 449: Citrus Postharvest Green Mold: Recent Advances in Fungal Pathogenicity and Fruit Resistance Microorganisms doi: 10.3390/microorganisms8030449 Authors: Yulin Cheng Yunlong Lin Haohao Cao Zhengguo Li As the major postharvest disease of citrus fruit, postharvest green mold is caused by the necrotrophic fungus Penicillium digitatum (Pd), which leads to huge economic losses worldwide. Fungicides are still the main method currently used to control...
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Molecules, Vol. 25, Pages 1453: Characterization, Quantification and Quality Assessment of Avocado (Persea americana Mill.) Oils Molecules doi: 10.3390/molecules25061453 Authors: Mei Wang Ping Yu Amar G. Chittiboyina Dilu Chen Jianping Zhao Bharathi Avula Yan-Hong Wang Ikhlas A. Khan Avocado oil is prized for its high nutritional value due to the substantial amounts of triglycerides (TGs) and unsaturated fatty acids (FAs) present. While avocado oil is traditionally...
Molecules, Vol. 25, Pages 1452: How Sure Can We Be about ML Methods-Based Evaluation of Compound Activity: Incorporation of Information about Prediction Uncertainty Using Deep Learning Techniques Molecules doi: 10.3390/molecules25061452 Authors: Sieradzki Leśniak Podlewska A great variety of computational approaches support drug design processes, helping in selection of new potentially active compounds, and optimization of their physicochemical and ADMET properties. Machine...
Molecules, Vol. 25, Pages 1451: New Cysteine Protease Inhibitors: Electrophilic (Het)arenes and Unexpected Prodrug Identification for the Trypanosoma Protease Rhodesain Molecules doi: 10.3390/molecules25061451 Authors: Klein Johe Wagner Jung Kühlborn Barthels Tenzer Distler Waigel Engels Hellmich Opatz Schirmeister Electrophilic (het)arenes can undergo reactions with nucleophiles yielding π- or Meisenheimer (σ-) complexes...
Molecules, Vol. 25, Pages 1449: Ellagic Acid Containing Nanostructured Lipid Carriers for Topical Application: A Preliminary Study Molecules doi: 10.3390/molecules25061449 Authors: Supandeep Singh Hallan Maddalena Sguizzato Gabriella Pavoni Anna Baldisserotto Markus Drechsler Paolo Mariani Elisabetta Esposito Rita Cortesi Ellagic acid (EA) is a potent antioxidant substance of natural origin characterized by poor biopharmaceutical properties and low solubility in...
Molecules, Vol. 25, Pages 1448: Removal of V(V) From Solution Using a Silica-Supported Primary Amine Resin: Batch Studies, Experimental Analysis, and Mathematical Modeling Molecules doi: 10.3390/molecules25061448 Authors: Huang Ye Chen Chen Liu Yin Wang Wei Every year, a large quantity of vanadium-containing wastewater is discharged from industrial factories, resulting in severe environmental problems. In particular, V(V) is recognized as a potentially hazardous...
Molecules, Vol. 25, Pages 1450: Major Contribution of Caspase-9 to Honokiol-Induced Apoptotic Insults to Human Drug-Resistant Glioblastoma Cells Molecules doi: 10.3390/molecules25061450 Authors: Gong-Jhe Wu Sun-Ta Yang Ruei-Ming Chen Temozolomide (TMZ)-induced chemoresistance to human glioblastomas is a critical challenge now. Our previous studies showed that honokiol, a major bioactive constituent of Magnolia officinalis (Houpo), can kill human glioblastoma cells and suppresses...
Molecules, Vol. 25, Pages 1445: Phosphonopeptides Revisited, in an Era of Increasing Antimicrobial Resistance Molecules doi: 10.3390/molecules25061445 Authors: Emma C.L. Marrs Linda Varadi Alexandre F. Bedernjak Kathryn M. Day Mark Gray Amanda L. Jones Stephen P. Cummings Rosaleen J. Anderson John D. Perry Given the increase in resistance to antibacterial agents, there is an urgent need for the development of new agents with novel modes of action. As an interim...
Molecules, Vol. 25, Pages 1444: NMR-Based Plant Metabolomics in Nutraceutical Research: An Overview Molecules doi: 10.3390/molecules25061444 Authors: Giovanna Valentino Vittoria Graziani Brigida D’Abrosca Severina Pacifico Antonio Fiorentino Monica Scognamiglio Few topics are able to channel the interest of researchers, the public, and industries, like nutraceuticals. The ever-increasing demand of new compounds or new sources of known active compounds, along with the need...
Molecules, Vol. 25, Pages 1446: Synthesis and Characterization of a Binuclear Copper(II)-dipyriamethyrin Complex: [Cu2(dipyriamethyrin)(μ2-1,1-acetato)2] Molecules doi: 10.3390/molecules25061446 Authors: James T. Brewster Harrison D. Root Hadiqa Zafar Gregory D. Thiabaud Adam C. Sedgwick Jiaming He Vincent M. Lynch Jonathan L. Sessler The reaction between dipyriamethyrin and copper(II) acetate [Cu(OAc)2] afforded what is, to our knowledge, the first transition metal-dipyriamethyrin...
Molecules, Vol. 25, Pages 1447: Design, Synthesis and Biological Evaluation of Phenyl Urea Derivatives as IDO1 Inhibitors Molecules doi: 10.3390/molecules25061447 Authors: Zhou Lai Sheng Chen Li Feng Indoleamine 2,3-dioxygenase 1 (IDO1) is a heme-containing intracellular enzyme that catalyzes the first and rate-determining step of tryptophan metabolism and is an important immunotherapeutic target for the treatment of cancer. In this study, we designed and synthesized...
Molecules, Vol. 25, Pages 1443: Kinetic Isotope Effects and Hydrogen Tunnelling in PCET Oxidations of Ascorbate: New Insights into Aqueous Chemistry? Molecules doi: 10.3390/molecules25061443 Authors: Ana Karković Marković Cvijeta Jakobušić Brala Viktor Pilepić Stanko Uršić Recent experimental studies of kinetic isotope effects (KIE-s) and hydrogen tunnelling comprising three proton-coupled electron transfer (PCET) oxidations of ascorbate monoanion, (a) in aqueous reaction solutions,...
Molecules, Vol. 25, Pages 1442: Discrimination of Gentiana and Its Related Species Using IR Spectroscopy Combined with Feature Selection and Stacked Generalization Molecules doi: 10.3390/molecules25061442 Authors: Shen Yu Wang s: Gentiana, which is one of the largest genera of Gentianoideae, most of which had potential pharmaceutical value, and applied to local traditional medical treatment. Because of the phytochemical diversity and difference of bioactive compounds among species,...
Molecules, Vol. 25, Pages 1441: Amyloids: Regulators of Metal Homeostasis in the Synapse Molecules doi: 10.3390/molecules25061441 Authors: Kawahara Kato-Negishi Tanaka Conformational changes in amyloidogenic proteins, such as β-amyloid protein, prion proteins, and α-synuclein, play a critical role in the pathogenesis of numerous neurodegenerative diseases, including Alzheimer’s disease, prion disease, and Lewy body disease. The disease-associated...
Molecules, Vol. 25, Pages 1440: Unusual Polyhydroxylated Steroids from the Starfish Anthenoides laevigatus, Collected off the Coastal Waters of Vietnam Molecules doi: 10.3390/molecules25061440 Authors: Kicha Ha Malyarenko Kalinovsky Popov Malyarenko Thuy Long Ha Ivanchina Four new polyhydroxylated steroids 1–4 were isolated along with two previously known related steroids 5 and 6 from the methanolic extract of the starfish Anthenoides laevigatus...
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Nanomaterials, Vol. 10, Pages 588: Thermal Convection of Nanoliquid in a Double-Connected Chamber Nanomaterials doi: 10.3390/nano10030588 Authors: Ioan Pop Mikhail A. Sheremet Teodor Groşan Thermogravitational convective thermal transmission, inside a square differentially-heated chamber with a nanoliquid, has been examined in the presence of internal adiabatic or a thermally-conducting solid body. A single-phase nanoliquid approach is employed, based on the experimentally-extracted...
Nanomaterials, Vol. 10, Pages 587: Ecofriendly Synthesis and Insecticidal Application of Copper Nanoparticles against the Storage Pest Tribolium castaneum Nanomaterials doi: 10.3390/nano10030587 Authors: Mohamed T. El-Saadony Mohamed E. Abd El-Hack Ayman E. Taha Moustafa M. G. Fouda Jamaan S. Ajarem Saleh N. Maodaa Ahmed A. Allam Nashwa Elshaer In spite of great developments in the agricultural field and plant productivity in the last decades, the concern about the...
Nanomaterials, Vol. 10, Pages 583: NH3 Plasma-Treated Magnesium Doped Zinc Oxide in Biomedical Sensors with Electrolyte–Insulator–Semiconductor (EIS) Structure for Urea and Glucose Applications Nanomaterials doi: 10.3390/nano10030583 Authors: Chun Fu Lin Chyuan Haur Kao Chan Yu Lin Kuan Lin Chen Yun Hao Lin This study compared the sensing characteristics of ZnO (ZO) treated with ammonia (NH3) plasma for 1 min, 3 min, and 6 min, under the EIS structure. The measurement results...
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