IJMS, Vol. 21, Pages 2231: Effect of a Resveratrol/Quercetin Mixture on the Reversion of Hypertension Induced by a Short-Term Exposure to High Sucrose Levels Near Weaning and a Long-Term Exposure That Leads to Metabolic Syndrome in Rats International Journal of Molecular Sciences doi: 10.3390/ijms21062231 Authors: Vicente Castrejón-Téllez Mariana Villegas-Romero María Esther Rubio-Ruiz Israel Pérez-Torres Elizabeth Carreón-Torres Eulises Díaz-Díaz Verónica Guarner-Lans ...
Mon Mar 23, 2020 02:00
IJMS, Vol. 21, Pages 2236: Enhancement of Neurite Outgrowth by Warming Biomaterial Ultrasound Treatment International Journal of Molecular Sciences doi: 10.3390/ijms21062236 Authors: Jung-Chih Chen Chao-Ming Su Gin-Shin Chen Chin-Chun Lai Ching-Yun Chen Kurt Ming-Chao Lin Feng-Huei Lin Guo-Chung Dong Ultrasound is a method for enhancing neurite outgrowth because of its thermal effect. In order to reach the working temperature to enhance neurite outgrowth, long-time...
Mon Mar 23, 2020 02:00
IJMS, Vol. 21, Pages 2234: Overcoming Shellfish Allergy: How Far Have We Come? International Journal of Molecular Sciences doi: 10.3390/ijms21062234 Authors: Wai Leung Chu Leung Leung Wong Leung Shellfish allergy caused by undesirable immunological responses upon ingestion of crustaceans and mollusks is a common cause of food allergy, especially in the Asia-Pacific region. While the prevalence of shellfish allergy is increasing, the mainstay of clinical diagnosis...
Mon Mar 23, 2020 02:00
IJMS, Vol. 21, Pages 2233: Forkhead Box P3 Methylation and Expression in Men with Obstructive Sleep Apnea International Journal of Molecular Sciences doi: 10.3390/ijms21062233 Authors: David Sanz-Rubio Arianne Sanz Luis Varona Rosa Bolea Marta Forner Ana V. Gil Pablo Cubero Marta Marin-Oto Inmaculada Martin-Burriel Jose M. Marin Background: Epigenetic changes in obstructive sleep apnea (OSA) have been proposed as a mechanism for end-organ vulnerability. In...
Mon Mar 23, 2020 02:00
IJMS, Vol. 21, Pages 2235: Synthesis, Anticancer Evaluation and Structure-Activity Analysis of Novel (E)- 5-(2-Arylvinyl)-1,3,4-oxadiazol-2-yl)benzenesulfonamides International Journal of Molecular Sciences doi: 10.3390/ijms21062235 Authors: Krzysztof Szafrański Jarosław Sławiński Łukasz Tomorowicz Anna Kawiak To learn more about the structure–activity relationships of (E)-3-(5-styryl-1,3,4-oxadiazol-2-yl)benzenesulfonamide derivatives, which in our previous research...
Mon Mar 23, 2020 02:00
IJMS, Vol. 21, Pages 2230: Fatty Acid Binding Protein 3 Enhances the Spreading and Toxicity of α-Synuclein in Mouse Brain International Journal of Molecular Sciences doi: 10.3390/ijms21062230 Authors: Yasushi Yabuki Kazuya Matsuo Ichiro Kawahata Naoya Fukui Tomohiro Mizobata Yasushi Kawata Yuji Owada Norifumi Shioda Kohji Fukunaga Oligomerization and/or aggregation of α-synuclein (α-Syn) triggers α-synucleinopathies such as Parkinson’s...
Mon Mar 23, 2020 02:00
IJMS, Vol. 21, Pages 2229: MiRNAs in the Peri-Implantation Period: Contribution to Embryo–Maternal Communication in Pigs International Journal of Molecular Sciences doi: 10.3390/ijms21062229 Authors: Monika M. Kaczmarek Joanna Najmula Maria M. Guzewska Emilia Przygrodzka MicroRNAs (miRNAs) constitute a large family of noncoding RNAs, approximately 22 nucleotides long, which function as guide molecules in RNA silencing. Targeting most protein-coding transcripts, miRNAs are involved...
Mon Mar 23, 2020 02:00
IJMS, Vol. 21, Pages 2227: Aromatase Inhibitors as Adjuvant Treatment for ER/PgR Positive Stage I Endometrial Carcinoma: A Retrospective Cohort Study International Journal of Molecular Sciences doi: 10.3390/ijms21062227 Authors: Laura Paleari Mariangela Rutigliani Giacomo Siri Nicoletta Provinciali Nicoletta Colombo Andrea Decensi Objective: Although endometrial cancer (EC) is a hormone dependent neoplasm, there are no recommendations for the determination of steroid hormone...
Mon Mar 23, 2020 02:00
IJMS, Vol. 21, Pages 2222: Recombination Pattern Characterization via Simulation Using Different Maize Populations International Journal of Molecular Sciences doi: 10.3390/ijms21062222 Authors: Wei Ren Xiaoping Gong Kun Li Hongwei Zhang Fanjun Chen Qingchun Pan Efficient recombination is critical to both plant breeding and gene cloning. However, almost all traditional recombination studies and genetic improvements require the slow and labor-intensive population construction...
Mon Mar 23, 2020 02:00
IJMS, Vol. 21, Pages 2228: Forefront: MiR-34a-Knockout Mice with Wild Type Hematopoietic Cells, Retain Persistent Fibrosis Following Lung Injury International Journal of Molecular Sciences doi: 10.3390/ijms21062228 Authors: Raanan Bulvik Moshe Biton Neville Berkman Raphael Breuer Shulamit B. Wallach-Dayan MicroRNAs (miRs) are known to limit gene expression at the post-transcriptional level and have important roles in the pathogenesis of various conditions, including acute...
Mon Mar 23, 2020 02:00
IJMS, Vol. 21, Pages 2232: Light and Circadian Signaling Pathway in Pregnancy: Programming of Adult Health and Disease International Journal of Molecular Sciences doi: 10.3390/ijms21062232 Authors: Chien-Ning Hsu You-Lin Tain Light is a crucial environmental signal that affects elements of human health, including the entrainment of circadian rhythms. A suboptimal environment during pregnancy can increase the risk of offspring developing a wide range of chronic diseases in later life....
Mon Mar 23, 2020 02:00
IJMS, Vol. 21, Pages 2225: Structures of Human Transglutaminase 2: Finding Clues for Interference in Cross-linking Mediated Activity International Journal of Molecular Sciences doi: 10.3390/ijms21062225 Authors: Gi Eob Kim Hyun Ho Park Human transglutaminase 2 (TGase2) has various functions, including roles in various cellular processes such as apoptosis, development, differentiation, wound healing, and angiogenesis, and is linked to many diseases such as cancer. Although TGase2 has...
Mon Mar 23, 2020 02:00
IJMS, Vol. 21, Pages 2224: Characteristics and Antimicrobial Properties of Active Edible Films Based on Pectin and Nanochitosan International Journal of Molecular Sciences doi: 10.3390/ijms21062224 Authors: Thi Minh Phuong Ngo Thanh Hoi Nguyen Thi Mong Quyen Dang Thi Xo Tran Pornchai Rachtanapun This study was aimed at creating new films and determine some functional packaging properties of pectin:nanochitosan films with ratios of pectin:nanochitosan (P:NSC) of 100:0; 75:25;...
Mon Mar 23, 2020 02:00
IJMS, Vol. 21, Pages 2223: Functional Analysis of Rice Long-Chain Acyl-CoA Synthetase 9 (OsLACS9) in the Chloroplast Envelope Membrane International Journal of Molecular Sciences doi: 10.3390/ijms21062223 Authors: Aya Kitajima-Koga Marouane Baslam Yuuki Hamada Namiko Ito Tomoko Taniuchi Takeshi Takamatsu Kazusato Oikawa Kentaro Kaneko Toshiaki Mitsui The long-chain acyl-CoA synthetases (LACSs) are involved in lipid synthesis, fatty acid catabolism, and the transport...
Mon Mar 23, 2020 02:00
IJMS, Vol. 21, Pages 2226: Alpha-Glucosidase Inhibitor Voglibose Suppresses Azoxymethane-Induced Colonic Preneoplastic Lesions in Diabetic and Obese Mice International Journal of Molecular Sciences doi: 10.3390/ijms21062226 Authors: Junichi Kato Yohei Shirakami Taku Mizutani Masaya Kubota Hiroyasu Sakai Takashi Ibuka Masahito Shimizu Type 2 diabetes mellitus and its related insulin resistance are known to increase the risk of cancer. Anti-diabetic agents can improve...
Mon Mar 23, 2020 02:00
IJMS, Vol. 21, Pages 2220: DNA Methylation in Neurodegenerative and Cerebrovascular Diseases Disorders International Journal of Molecular Sciences doi: 10.3390/ijms21062220 Authors: Olaia Martínez-Iglesias Iván Carrera Juan Carlos Carril Lucía Fernández-Novoa Natalia Cacabelos Ramón Cacabelos DNA methylation is an epigenetic mechanism by which methyl groups are added to DNA, playing a crucial role in gene expression regulation. The aim of the present study is to compare...
Mon Mar 23, 2020 02:00
IJMS, Vol. 21, Pages 2221: Type 1 FSHD with 6–10 Repeated Units: Factors Underlying Severity in Index Cases and Disease Penetrance in Their Relatives Attention International Journal of Molecular Sciences doi: 10.3390/ijms21062221 Authors: Emmanuelle Salort-Campana Farzad Fatehi Sadia Beloribi-Djefaflia Stéphane Roche Karine Nguyen Rafaelle Bernard Pascal Cintas Guilhem Solé Françoise Bouhour Elisabeth Ollagnon Sabrina Sacconi Andoni Echaniz-Laguna Thierry...
Mon Mar 23, 2020 02:00
IJMS, Vol. 21, Pages 2219: Arbuscular Mycorrhizal Symbiosis Mitigates Iron (Fe)-Deficiency Retardation in Alfalfa (Medicago sativa L.) Through the Enhancement of Fe Accumulation and Sulfur-Assisted Antioxidant Defense International Journal of Molecular Sciences doi: 10.3390/ijms21062219 Authors: Md. Atikur Rahman Monika Parvin Urmi Das Esrat Jahan Ela Sang-Hoon Lee Ki-Won Lee Ahmad Humayan Kabir Iron (Fe)-deficiency is one of the major constraints affecting growth,...
Mon Mar 23, 2020 02:00
IJMS, Vol. 21, Pages 2218: Glucose and Blood Pressure-Dependent Pathways–The Progression of Diabetic Kidney Disease International Journal of Molecular Sciences doi: 10.3390/ijms21062218 Authors: Devang M. Patel Madhura Bose Mark E. Cooper The major clinical associations with the progression of diabetic kidney disease (DKD) are glycemic control and systemic hypertension. Recent studies have continued to emphasize vasoactive hormone pathways including aldosterone and endothelin which...
Mon Mar 23, 2020 02:00
IJMS, Vol. 21, Pages 2217: Plant-Based Antidiabetic Nanoformulations: The Emerging Paradigm for Effective Therapy International Journal of Molecular Sciences doi: 10.3390/ijms21062217 Authors: Saikat Dewanjee Pratik Chakraborty Biswajit Mukherjee Vincenzo De Feo Diabetes mellitus is a life-threatening metabolic syndrome. Over the past few decades, the incidence of diabetes has climbed exponentially. Several therapeutic approaches have been undertaken, but the occurrence and...
Mon Mar 23, 2020 02:00
IJMS, Vol. 21, Pages 2213: Calcineurin Controls Expression of EAAT1/GLAST in Mouse and Human Cultured Astrocytes through Dynamic Regulation of Protein Synthesis and Degradation International Journal of Molecular Sciences doi: 10.3390/ijms21062213 Authors: Giulia Dematteis Elena Restelli Roberto Chiesa Eleonora Aronica Armando A Genazzani Dmitry Lim Laura Tapella Alterations in the expression of glutamate/aspartate transporter (GLAST) have been associated with several...
Mon Mar 23, 2020 02:00
IJMS, Vol. 21, Pages 2215: The IL-17A/IL-17RA Axis Is Not Related to Overall Survival and Cancer Stem Cell Modulation in Pancreatic Cancer International Journal of Molecular Sciences doi: 10.3390/ijms21062215 Authors: Jiahui Li Christopher Betzler Philipp Lohneis Marie Christine Popp Jiwei Qin Thomas Kalinski Thomas Wartmann Christiane J. Bruns Yue Zhao Felix C. Popp (1) Background: IL-17A accelerates pancreatic intraepithelial neoplasia (PanIN) progression....
Mon Mar 23, 2020 02:00
IJMS, Vol. 21, Pages 2216: Fli-1 Activation through Targeted Promoter Activity Regulation Using a Novel 3’, 5’-diprenylated Chalcone Inhibits Growth and Metastasis of Prostate Cancer Cells International Journal of Molecular Sciences doi: 10.3390/ijms21062216 Authors: Youfen Ma Bixue Xu Jia Yu Lirong Huang Xiaoping Zeng Xiangchun Shen Chunyan Ren Yaacov Ben-David Heng Luo The friend leukemia integration 1 (Fli-1) gene is involved in the expression control of key...
Mon Mar 23, 2020 02:00
IJMS, Vol. 21, Pages 2212: Metabolites Produced by the Oral Commensal Bacterium Corynebacterium durum Extend the Lifespan of Caenorhabditis elegans via SIR-2.1 Overexpression International Journal of Molecular Sciences doi: 10.3390/ijms21062212 Authors: Jun Hyeong Kim In Hyuk Bang Yun Jeong Noh Dae Keun Kim Eun Ju Bae In Hyun Hwang Human microbiota is heavily involved in host health, including the aging process. Based on the hypothesis that the human microbiota manipulates...
Mon Mar 23, 2020 02:00
IJMS, Vol. 21, Pages 2211: Preparation and Characterization of Aptamers Against O,p’-DDT International Journal of Molecular Sciences doi: 10.3390/ijms21062211 Authors: Wei Zhang Danyang Li Jianguang Zhang Lingli Jiang Zhaofa Li Jun Sheng Lin The compound 1,1,1-trichloro-2-(p-chlorophenyl)-2-(o-chlorophenyl) ethane (o,p’-DDT) has been identified as one of the endocrine-disrupting chemicals causing adverse effects on wildlife and even humans through bioaccumulation....
Mon Mar 23, 2020 02:00
IJMS, Vol. 21, Pages 2207: Rapamycin Re-Directs Lysosome Network, Stimulates ER-Remodeling, Involving Membrane CD317 and Affecting Exocytosis, in Campylobacter Jejuni-Lysate-Infected U937 Cells International Journal of Molecular Sciences doi: 10.3390/ijms21062207 Authors: Barbara Canonico Erica Cesarini Mariele Montanari Gianna Di Sario Raffaella Campana Luca Galluzzi Federica Sola Ozan Gundogdu Francesca Luchetti Aurora Diotallevi Wally Baffone Antonio Giordano...
Mon Mar 23, 2020 02:00
IJMS, Vol. 21, Pages 2210: Analysis of Selenoprotein Expression in Response to Dietary Selenium Deficiency During Pregnancy Indicates Tissue Specific Differential Expression in Mothers and Sex Specific Changes in the Fetus and Offspring International Journal of Molecular Sciences doi: 10.3390/ijms21062210 Authors: Pierre Hofstee James S.M. Cuffe Anthony V. Perkins The human selenoproteome is comprised of ~25 genes, which incorporate selenium, in the form of selenocysteine, into...
Mon Mar 23, 2020 02:00
IJMS, Vol. 21, Pages 2214: Microgravity and Cell Adherence International Journal of Molecular Sciences doi: 10.3390/ijms21062214 Authors: Bauer Cell adhesion is an inevitable precondition for enabling cells to assemble into three-dimensional tissues [1]. Different cell adhesion mechanisms are responsible for determining the overall architecture of a tissue. Central elements of the cell adhesion systems are transmembrane proteins, which include various integrins, cadherins, immunoglobulins,...
Mon Mar 23, 2020 02:00
IJMS, Vol. 21, Pages 2209: Genome-Wide Analysis of Phosphorus Transporter Genes in Brassica and Their Roles in Heavy Metal Stress Tolerance International Journal of Molecular Sciences doi: 10.3390/ijms21062209 Authors: Yuanyuan Wan Zhen Wang Jichun Xia Shulin Shen Mingwei Guan Meichen Zhu Cailin Qiao Fujun Sun Ying Liang Jiana Li Kun Lu Cunmin Qu Phosphorus transporter (PHT) genes encode H2PO4−/H+ co-transporters that absorb and transport inorganic...
Mon Mar 23, 2020 02:00
IJMS, Vol. 21, Pages 2208: Comparative Analysis of High-Throughput Assays of Family-1 Plant Glycosyltransferases International Journal of Molecular Sciences doi: 10.3390/ijms21062208 Authors: Kate McGraphery Wilfried Schwab The ability of glycosyltransferases (GTs) to reduce volatility, increase solubility, and thus alter the bioavailability of small molecules through glycosylation has attracted immense attention in pharmaceutical, nutraceutical, and cosmeceutical industries. The...
Mon Mar 23, 2020 02:00
IJMS, Vol. 21, Pages 2206: VLA-4 Expression and Activation in B Cell Malignancies: Functional and Clinical Aspects International Journal of Molecular Sciences doi: 10.3390/ijms21062206 Authors: Andrea Härzschel Antonella Zucchetto Valter Gattei Tanja Nicole Hartmann Lineage commitment and differentiation of hematopoietic cells takes place in well-defined microenvironmental surroundings. Communication with other cell types is a vital prerequisite for the normal functions of the...
Mon Mar 23, 2020 02:00
IJMS, Vol. 21, Pages 2204: Research Models for Studying Vascular Calcification International Journal of Molecular Sciences doi: 10.3390/ijms21062204 Authors: Jaqueline Herrmann Milen Babic Markus Tölle Markus van der Giet Mirjam Schuchardt Calcification of the vessel wall contributes to high cardiovascular morbidity and mortality. Vascular calcification (VC) is a systemic disease with multifaceted contributing and inhibiting factors in an actively regulated process. The exact...
Mon Mar 23, 2020 02:00
IJMS, Vol. 21, Pages 2201: Origins of Alterations to Rankl Null Mutant Mouse Dental Root Development
IJMS, Vol. 21, Pages 2201: Origins of Alterations to Rankl Null Mutant Mouse Dental Root Development International Journal of Molecular Sciences doi: 10.3390/ijms21062201 Authors: Andrea Gama Jorge William Vargas-Franco Diana Carolina Sánchez Mesa Elizabeth Restrepo Bedoya Jérome Amiaud Sylvie Babajko Ariane Berdal Ana Carolina Acevedo Dominique Heymann Frédéric Lézot Beatriz Castaneda The purpose of the present study was to assess the early stages of development...
Mon Mar 23, 2020 02:00
IJMS, Vol. 21, Pages 2205: Completing Autophagy: Formation and Degradation of the Autophagic Body and Metabolite Salvage in Plants International Journal of Molecular Sciences doi: 10.3390/ijms21062205 Authors: Szymon Stefaniak Łukasz Wojtyla Małgorzata Pietrowska-Borek Sławomir Borek Autophagy is an evolutionarily conserved process that occurs in yeast, plants, and animals. Despite many years of research, some aspects of autophagy are still not fully explained. This mostly concerns...
Mon Mar 23, 2020 02:00
IJMS, Vol. 21, Pages 2203: SUMOylation Is Required for ERK5 Nuclear Translocation and ERK5-Mediated Cancer Cell Proliferation International Journal of Molecular Sciences doi: 10.3390/ijms21062203 Authors: Tatiana Erazo Sergio Espinosa-Gil Nora Diéguez-Martínez Néstor Gómez Jose M Lizcano The MAP kinase ERK5 contains an N-terminal kinase domain and a unique C-terminal tail including a nuclear localization signal and a transcriptional activation domain. ERK5 is activated in...
Mon Mar 23, 2020 02:00
IJMS, Vol. 21, Pages 2202: Apical Sodium-Dependent Bile Acid Cotransporter, A Novel Transporter of Indocyanine Green, and Its Application in Drug Screening International Journal of Molecular Sciences doi: 10.3390/ijms21062202 Authors: Menq-Rong Wu Jong-Kai Hsiao Bile acid plays critical roles in the elimination of inorganic compounds such as bilirubin, heavy metals, and drug metabolites. Apical sodium-dependent bile acid cotransporter (ASBT), a solute carrier membrane transport protein,...
Mon Mar 23, 2020 02:00
IJMS, Vol. 21, Pages 2200: Myocyte Enhancer Factor 2A (MEF2A) Defines Oxytocin-Induced Morphological Effects and Regulates Mitochondrial Function in Neurons International Journal of Molecular Sciences doi: 10.3390/ijms21062200 Authors: Magdalena Meyer Kerstin Kuffner Julia Winter Inga D. Neumann Christian H. Wetzel Benjamin Jurek The neuropeptide oxytocin (OT) is a well-described modulator of socio-emotional traits, such as anxiety, stress, social behavior, and pair bonding....
Mon Mar 23, 2020 02:00
IJMS, Vol. 21, Pages 2199: OsINV3 and Its Homolog, OsINV2, Control Grain Size in Rice International Journal of Molecular Sciences doi: 10.3390/ijms21062199 Authors: Xiaoshu Deng Xiaohang Han Shicong Yu Zhijian Liu Daiming Guo Yao He Wenyi Li Yu Tao Chaowei Sun Peizhou Xu Yongxiang Liao Xiaoqiong Chen Hongyu Zhang Xianjun Wu Vacuolar invertase is involved in sugar metabolism and plays a crucial role in plant growth and development, thus regulating...
Mon Mar 23, 2020 02:00
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