Abstract Purpose The optimal pain management concept in children after tonsil surgery is controversial. Ibuprofen on an “around-the-clock” basis has been suggested to control postoperative pain sufficiently. Therefore, we established a standard scheme with weight-adapted recommended maximum ibuprofen dose. A reliable assessment of pain intensity can be performed with the Children’s and Infants’ Postoperative Pain Scale (CHIPPS) in children < 5 years,...
2d
Abstract The ongoing opioid crisis, now into its second decade, represents a global public health challenge. Moreover, the opioid crisis has manifested despite clinical access to three approved opioid use disorder medications: the full opioid agonist methadone, the partial opioid agonist buprenorphine, and the opioid antagonist naltrexone. Although current opioid use disorder medications are underutilized, the ongoing opioid crisis has also identified the need for basic research...
1d
Abstract The pervasive and devastating nature of substance use disorders underlies the need for the continued development of novel pharmacotherapies. We now know that glia play a much greater role in neuronal processes than once believed. The various types of glial cells (e.g., astrocytes, microglial, oligodendrocytes) participate in numerous functions that are crucial to healthy central nervous system function. Drugs of abuse have been shown to interact with glia in ways that...
2d
Abstract Aripiprazole, brexpiprazole and cariprazine differ from all other second-generation antipsychotics due to partial agonism at the dopamine D2 and D3 receptors. In contrast to aripiprazole, brexpiprazole has lower intrinsic dopamine D2 activity and higher affinity for the serotonin 5-HT1A and 5-HT2A receptors, while cariprazine has the highest affinity for the dopamine D3 receptor, and the longest half-life. The main adverse effect of dopamine receptor partial agonists (DRPAs)...
2d
Publication date: March 2020Source: Operative Techniques in Otolaryngology-Head and Neck Surgery, Volume 31, Issue 1Author(s):
1d
Biosensors, Vol. 10, Pages 34: Investigation of Photoplethysmography Behind the Ear for Pulse Oximetry in Hypoxic Conditions with a Novel Device (SPYDR) Biosensors doi: 10.3390/bios10040034 Authors: Brian Bradke Bradford Everman Photoplethysmography (PPG) is a valuable technique for noninvasively evaluating physiological parameters. However, traditional PPG devices have significant limitations in high-motion and low-perfusion environments. To overcome these limitations, we investigated...
1d
Publication date: Available online 3 April 2020Source: Biochimica et Biophysica Acta (BBA) - General SubjectsAuthor(s): Taiki Noguchi, Mayuko Ikeda, Masaru Murakami, Mikio Masuzawa, Toru Imamura, Osamu Hashimoto, Tohru Matsui, Masayuki Funaba
1d
Validation of the concavity–convexity quotient as a new method to measure the magnitude of scoliosis
Gonzalo Mariscal, Jorge H Nuñez, Paulo Figueira, Ana Malo, Verónica Montiel, Miguel A López, Miguel Castro, Carlos Barrios, Pedro Domenech FernJournal of Craniovertebral Junction and Spine 2020 11(1):31-35 Objectives: We propose a novel and simple method to determine the magnitude of the curve in scoliosis and its correlation with the Cobb angle. Methods: Using multiple rounds of nominal group technique and an established consensus-building methodology, a multidisciplinary research group identified...
1d
Mohit Patel, Hesham Abboud, Manish K KasliwalJournal of Craniovertebral Junction and Spine 2020 11(1):55-56
1d
Reddy RavikanthJournal of Craniovertebral Junction and Spine 2020 11(1):4-8 This review article describes the various image guided interventional techniques used for treating chronic backache attributed to disc related pathologies. With the aim of minimum invasion and maximum relief, these procedures comprise predominantly of annuloplasty and disc decompression via different mechanisms. Newer therapies are discussed in this review article with the objective of restoring disc height and its biomechanical...
1d
Atul Goel, Dikpal Jadhav, Abhidha Shah, Survendra Rai, Saswat Dandpat, Neha Jadhav, Tejas VajaJournal of Craniovertebral Junction and Spine 2020 11(1):46-50 Objective: The authors analyze the rationale of atlantoaxial fixation in patients presenting with symptoms related to cervical myelopathy and wherein the radiological images depicted C2–3 fusion and presence of single or multiple level neural compression of the subaxial cervical spinal cord attributed to “degenerative” spine. Materials and...
1d
Incidence and risk factors of reoperation in patients with adjacent segment disease: A meta-analysis
Major B Burch, Nicholas W Wiegers, Sonal Patil, Ali NourbakhshJournal of Craniovertebral Junction and Spine 2020 11(1):9-16 Study Design: This was a systematic review of the literature and meta-analysis. Objective: The objective of this study was to evaluate the current literature regarding the risk factors contributing to reoperation due to adjacent segment disease (ASD). Summary of Background Data: ASD is a broad term referring to a variety of complications which might require reoperation....
1d
Atul GoelJournal of Craniovertebral Junction and Spine 2020 11(1):1-3
1d
Thirumal Yeraagunta, Vamsi Krishna Yerramneni, Ramanadha Reddy Kanala, Govind Gaikwad, H D Pradeep Kumar, Aniket Sharad PhutaneJournal of Craniovertebral Junction and Spine 2020 11(1):17-21 Objective: The objective was to study the results of the treatment of thoracolumbar spondylodiscitis (SD) through minimally invasive fusion and decompression technique. Materials and Methods: All the patients were evaluated clinically and radiologically (X-ray, magnetic resonance imaging, and computed tomography...
1d
Punit Tiwari, Harmeet Kaur, Harpreet Kaur, Vivek Jha, Navneet Singh, Arshad AshrafJournal of Craniovertebral Junction and Spine 2020 11(1):36-45 Introduction: People living in the mountains are subject to tough terrain and climbing biomechanics which lead to degeneration of the spine and Facet joint arthritis (FJA). Aims: The goal of present study was (1) to know the prevalence of facet joint arthritis on CT scans in mountain population in regard to (a) different levels in spine (b) age (c) sex...
1d
Keyvan Mostofi, Morad Peyravi, Babak Gharaei MoghadamJournal of Craniovertebral Junction and Spine 2020 11(1):22-25 Background: C7-D1 disc herniation is rare in comparison with other cervical levels. The incidence rates are between 3.5% and 8%. The cervicothoracic junction disc herniation can be operated posteriorly or anteriorly. The anterior approach can be challenging because of the difficulty of access resulted from the manubrium. In this article, we present our experience about cervicothoracic...
1d
Atul Goel, Shashi Ranjan, Abhidha Shah, Survendra Rai, Saswat Dandpat, Abhinandan Patil, Ravikiran VuthaJournal of Craniovertebral Junction and Spine 2020 11(1):51-54 Aim: We report adjacent-segment “central” or “axial” atlantoaxial instability and C2–C3 instability as the cause of delayed neurological worsening following multisegmental cervical spinal stabilization. Materials and Methods: Three male patients aged 34, 56, and 70 years had been operated earlier for cervical spondylosis by multilevel...
1d
Alessandro Rava, Eugenio Dema, Matteo Palmisani, Rosa Palmisani, Stefano Cervellati, Massimo GirardoJournal of Craniovertebral Junction and Spine 2020 11(1):26-30 Background: In patients with Marfan syndrome (MFS), surgical correction of spinal deformities with hooks and/or pedicle screws involves a higher rate of complications than in patients with adolescent idiopathic scoliosis. Therefore, sublaminar instrumentation is often a last resort option. This study wants to assess the ability of sublaminar...
1d
Nabanita Ghosh, Prasad KrishnanJournal of Craniovertebral Junction and Spine 2020 11(1):57-58
1d
Summary Dasatinib is a tyrosine kinase inhibitor for the treatment of BCR-ABL-positive chronic myeloid leukaemia (CML) or Philadelphia chromosome-positive acute lymphoblastic leukaemia (ALL). Although fluid retention is a common adverse event associated with dasatinib, chylothorax is exceptionally rare. The pathological mechanism, clinical manifestation and management of dasatinib-induced chylothorax are completely unclear. A 71-year-old man treated with dasatinib for CML was admitted...
1d
Summary Introduction TAS-114 is a potent inhibitor of deoxyuridine triphosphatase, which is a gatekeeper protein preventing uracil and 5-fluorouracil (5-FU) misincorporation into DNA. TAS-114 has been suggested to enhance the antitumor activity of 5-FU. This randomized, phase 2 study investigated TAS-114 plus S-1 (TAS-114/S-1) vs. S-1 in non-small-cell lung cancer (NSCLC) patients. Methods Patients with advanced NSCLC, previously treated with ≥ 2 regimens, were randomized 1:1 to...
2d
Publication date: Available online 3 April 2020Source: Journal of Dairy ScienceAuthor(s): B. McClearn, L. Delaby, T.J. Gilliland, C. Guy, M. Dineen, F. Coughlan, F. Buckley, B. McCarthy
1d
Publication date: Available online 3 April 2020Source: Journal of Dairy ScienceAuthor(s): M.B. Samarasinghe, J. Sehested, T. Larsen, L.E. Hernández-Castellano
1d
Publication date: Available online 3 April 2020Source: Journal of Dairy ScienceAuthor(s): H. Ben Zaabza, E.A. Mäntysaari, I. Strandén
1d
Publication date: Available online 3 April 2020Source: Journal of Dairy ScienceAuthor(s): Marin M. Western, Jonas de Souza, Adam L. Lock
1d
Publication date: Available online 3 April 2020Source: Journal of Dairy ScienceAuthor(s): J.J. Gross, L. Grossen-Rösti, S.K. Wall, O. Wellnitz, R.M. Bruckmaier
1d
Publication date: Available online 3 April 2020Source: Journal of Dairy ScienceAuthor(s): Ricardo C. Chebel, Thiago Cunha
1d
Publication date: Available online 3 April 2020Source: Journal of Dairy ScienceAuthor(s): I. Granado-Tajada, S.T. Rodríguez-Ramilo, A. Legarra, E. Ugarte
1d
Publication date: Available online 3 April 2020Source: Journal of Dairy ScienceAuthor(s): Siqi Li, Aiqian Ye, Harjinder Singh
1d
Publication date: Available online 3 April 2020Source: Journal of Dairy ScienceAuthor(s): H. Gong, J. Gao, Y. Wang, Q.W. Luo, K.R. Guo, F.Z. Ren, X.Y. Mao
1d
Publication date: Available online 3 April 2020Source: Journal of Dairy ScienceAuthor(s): B. Dolatkhah, G.R. Ghorbani, M. Alikhani, F. Hashemzadeh, A.H. Mahdavi, A. Sadeghi-Sefidmazgi, H. Erfani, P. Rezamand
1d
Publication date: Available online 3 April 2020Source: Journal of Dairy ScienceAuthor(s): Alycia M. Drwencke, Grazyne Tresoldi, Matthew M. Stevens, Vinod Narayanan, Angelica V. Carrazco, Frank M. Mitloehner, Theresa E. Pistochini, Cassandra B. Tucker
1d
HOXC8 inhibited the osteo‐/dentinogenic differentiation and migration ability of stem cells of the apical papilla (SCAPs) via activating KDM1A. HOXC8 regulated transcription of KDM1A by binding to the KDM1A promoter in SCAPs. Abstract Enhancing the functions of mesenchymal stem cells (MSCs) is considered a potential approach for promoting tissue regeneration. In the present study, we investigate the role of HOXC8 in regulating differentiation and migration by using stem cells of the apical papilla...
1d
Publication date: Available online 3 April 2020Source: Cancer LettersAuthor(s): Renato Cuocolo, Martina Caruso, Teresa Perillo, Lorenzo Ugga, Mario Petretta
1d
Publication date: Available online 3 April 2020Source: Cancer LettersAuthor(s): Nikolai Jaschke, Lorenz C. Hofbauer, Andy Göbel, Tilman D. Rachner
1d
Publication date: Available online 2 April 2020Source: Cancer LettersAuthor(s): B.C. Baljer, Kolhe S, C.D. Chan, Nicoli F, Ghanbasha A, Brookes MJ, Gamie Z, Ghosh KM, Beckingsale TB, Saleh DB, Ragbir M, Gerrand CH, Jeys L, Knight JC, Petrides G, Rankin KS
2d
Related ArticlesPhysiological changes in the size of the septal swell body correlate with changes in inferior turbinate size. J Laryngol Otol. 2020 Apr 03;:1-5 Authors: Wong EH, Noussair M, Hasan Z, Duvnjak M, Singh N Abstract OBJECTIVE: The nasal septal swell body is a normal anatomical structure located in the superior nasal septum anterior to the middle turbinate. However, the impact of the septal swell body in nasal breathing during normal function...
1d
Related ArticlesMagnetic resonance imaging of Ménière's disease: early clinical experience in a UK centre. J Laryngol Otol. 2020 Apr 03;:1-9 Authors: Pai I, Mendis S, Murdin L, Touska P, Connor S Abstract BACKGROUND: Recent developments in magnetic resonance imaging have enabled demonstration of endolymphatic hydrops, and the clinical application of these imaging studies in Ménière's disease is being explored. OBJECTIVE: To evaluate our centre's...
1d
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου