Κυριακή 12 Ιουλίου 2020


Kupffer cells promote T-cell hepatitis by producing CXCL10 and limiting liver sinusoidal endothelial cell permeability.
Related Articles Kupffer cells promote T-cell hepatitis by producing CXCL10 and limiting liver sinusoidal endothelial cell permeability. Theranostics. 2020;10(16):7163-7177 Authors: Dai S, Liu F, Qin Z, Zhang J, Chen J, Ding WX, Feng D, Ji Y, Qin X Abstract Rationale: Kupffer cells (KCs) play a crucial role in liver immune homeostasis through interacting with other immune cells and liver sinusoidal endothelial cells (LSECs). However, how KCs...
Alcohol and Homeostasis
Fri Jul 10, 2020 15:38
Azoreductase-Responsive Nanoprobe for Hypoxia-Induced Mitophagy Imaging.
Related Articles Azoreductase-Responsive Nanoprobe for Hypoxia-Induced Mitophagy Imaging. Anal Chem. 2019 01 15;91(2):1360-1367 Authors: Ma D, Huang C, Zheng J, Zhou W, Tang J, Chen W, Li J, Yang R Abstract Mitophagy, as a crucial metabolic process, plays an essential role in maintaining cellular and tissue homeostasis. Various stresses especially hypoxia could improve intracellular reactive oxygen species (ROS) level to induce mitophagy. However,...
Alcohol and Homeostasis
Fri Jul 10, 2020 15:38
Dietary Lipids Induce Ferroptosis in Caenorhabditiselegans and Human Cancer Cells.
Related Articles Dietary Lipids Induce Ferroptosis in Caenorhabditiselegans and Human Cancer Cells. Dev Cell. 2020 Jun 30;: Authors: Perez MA, Magtanong L, Dixon SJ, Watts JL Abstract Dietary lipids impact development, homeostasis, and disease, but links between specific dietary fats and cell fates are poorly understood. Ferroptosis is an iron-dependent form of nonapoptotic cell death associated with oxidized polyunsaturated phospholipids. Here,...
Human homeostasis
Sun Jul 12, 2020 17:06
Extremely low-frequency electromagnetic field induces a change in proliferative capacity and redox homeostasis of human lung fibroblast cell line MRC-5.
Related Articles Extremely low-frequency electromagnetic field induces a change in proliferative capacity and redox homeostasis of human lung fibroblast cell line MRC-5. Environ Sci Pollut Res Int. 2020 Jul 10;: Authors: Lekovic MH, Drekovic NE, Granica ND, Mahmutovic EH, Djordjevic NZ Abstract Numerous studies have shown that extremely low-frequency electromagnetic field (ELF-EMF) by modulating oxidative-antioxidative balance in the cells achieved...
Human homeostasis
Sun Jul 12, 2020 13:07
Bassoon inhibits proteasome activity via interaction with PSMB4.
Related Articles Bassoon inhibits proteasome activity via interaction with PSMB4. Cell Mol Life Sci. 2020 Jul 10;: Authors: Montenegro-Venegas C, Fienko S, Anni D, Pina-Fernández E, Frischknecht R, Fejtova A Abstract Proteasomes are protein complexes that mediate controlled degradation of damaged or unneeded cellular proteins. In neurons, proteasome regulates synaptic function and its dysfunction has been linked to neurodegeneration and neuronal...
Human homeostasis
Sun Jul 12, 2020 13:07
Efficient recovery of the RNA-bound proteome and protein-bound transcriptome using phase separation (OOPS).
Related Articles Efficient recovery of the RNA-bound proteome and protein-bound transcriptome using phase separation (OOPS). Nat Protoc. 2020 Jul 10;: Authors: Villanueva E, Smith T, Queiroz RML, Monti M, Pizzinga M, Elzek M, Dezi V, Harvey RF, Ramakrishna M, Willis AE, Lilley KS Abstract RNA-protein interactions play a pivotal role in cell homeostasis and disease, but current approaches to study them require a considerable amount of starting...
Human homeostasis
Sun Jul 12, 2020 13:07
Prion peptide-mediated calcium level alteration governs neuronal cell damage through AMPK-autophagy flux.
Related Articles Prion peptide-mediated calcium level alteration governs neuronal cell damage through AMPK-autophagy flux. Cell Commun Signal. 2020 Jul 11;18(1):109 Authors: Moon JH, Park SY Abstract BACKGROUND: The distinctive molecular structure of the prion protein, PrPsc, is established only in mammals with infectious prion diseases. Prion protein characterizes either the transmissible pathogen itself or a primary constituent of the disease....
Human homeostasis
Sun Jul 12, 2020 13:07
TIAM2S Mediates Serotonin Homeostasis and Provokes a Pro-Inflammatory Immune Microenvironment Permissive for Colorectal Tumorigenesis.
Related Articles TIAM2S Mediates Serotonin Homeostasis and Provokes a Pro-Inflammatory Immune Microenvironment Permissive for Colorectal Tumorigenesis. Cancers (Basel). 2020 Jul 08;12(7): Authors: Chan YL, Lai WC, Chen JS, Tseng JT, Chuang PC, Jou J, Lee CT, Sun HS Abstract The short isoform of human TIAM2 has been shown to promote proliferation and invasion in various cancer cells. However, the roles of TIAM2S in immune cells in relation to...
Human homeostasis
Sun Jul 12, 2020 13:07
Anti-atherogenic Modification of Serum Lipoprotein Function in Patients with Rheumatoid Arthritis after Tocilizumab Treatment, a Pilot Study.
Related Articles Anti-atherogenic Modification of Serum Lipoprotein Function in Patients with Rheumatoid Arthritis after Tocilizumab Treatment, a Pilot Study. J Clin Med. 2020 Jul 08;9(7): Authors: Greco D, Gualtierotti R, Agosti P, Adorni MP, Ingegnoli F, Rota M, Bernini F, Meroni PL, Ronda N Abstract Lipid metabolism derangement contributes to increased cardiovascular risk in Rheumatoid Arthritis (RA). It is still debated whether and how tocilizumab,...
Human homeostasis
Sun Jul 12, 2020 13:07
Intestinal Macrophages at the Crossroad between Diet, Inflammation, and Cancer.
Related Articles Intestinal Macrophages at the Crossroad between Diet, Inflammation, and Cancer. Int J Mol Sci. 2020 Jul 08;21(14): Authors: Caprara G, Allavena P, Erreni M Abstract Intestinal macrophages are key players in the regulation of the oral tolerance, controlling gut homeostasis by discriminating innocuous antigens from harmful pathogens. Diet exerts a significant impact on human health, influencing the composition of gut microbiota...
Human homeostasis
Sun Jul 12, 2020 13:07
human homeostasis; +36 new citations
36 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: human homeostasis These pubmed results were generated on 2020/07/11PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Human homeostasis
Sat Jul 11, 2020 17:04
human homeostasis; +36 new citations
36 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: human homeostasis These pubmed results were generated on 2020/07/11PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Human homeostasis
Sat Jul 11, 2020 13:04
human homeostasis; +46 new citations
46 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: human homeostasis These pubmed results were generated on 2020/07/10PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Human homeostasis
Fri Jul 10, 2020 17:04
human homeostasis; +46 new citations
46 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: human homeostasis These pubmed results were generated on 2020/07/10PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Human homeostasis
Fri Jul 10, 2020 13:03
High-protein diet more effectively reduces hepatic fat than low-protein diet despite lower autophagy and FGF21 levels.
Related Articles High-protein diet more effectively reduces hepatic fat than low-protein diet despite lower autophagy and FGF21 levels. Liver Int. 2020 Jul 11;: Authors: Xu C, Markova M, Seebeck N, Loft A, Hornemann S, Gantert T, Kabisch S, Herz K, Loske J, Ost M, Coleman V, Klauschen F, Rosenthal A, Lange V, Machann J, Klaus S, Grune T, Herzig S, Pivovarova-Ramich O, Pfeiffer AFH Abstract BACKGROUND AND AIMS: Non-alcoholic fatty liver disease...
Human physiology
Sun Jul 12, 2020 15:05
Detection of peanut allergens in serum: circumventing the inhibitory effect of immunoglobulins.
Related Articles Detection of peanut allergens in serum: circumventing the inhibitory effect of immunoglobulins. Allergy. 2020 Jul;75(7):1835-1836 Authors: Koppelman SJ, Witteveen M, JanssenDuijghuijsen L, Baumert JL, Witkamp RF, van Norren K PMID: 32652627 [PubMed - as supplied by publisher]
Human physiology
Sun Jul 12, 2020 15:05
Human Red Blood Cell Uptake and Sequestration of Arsenite and Selenite: Evidence of Seleno-bis(S-glutathionyl) Arsinium Ion Formation in Human Cells.
Related Articles Human Red Blood Cell Uptake and Sequestration of Arsenite and Selenite: Evidence of Seleno-bis(S-glutathionyl) Arsinium Ion Formation in Human Cells. Biochem Pharmacol. 2020 Jul 08;:114141 Authors: Kaur G, Javed W, Ponomarenko O, Shekh K, Swanlund DP, Zhou JR, Summers KL, Casini A, Wenzel M, Casey JR, Cordat E, Pickering IJ, George GN, Leslie EM Abstract Over 200 million people worldwide are exposed to the human carcinogen,...
Human physiology
Sun Jul 12, 2020 15:05
Breastmilk Feeding Practices Are Associated with the Co-Occurrence of Bacteria in Mothers' Milk and the Infant Gut: the CHILD Cohort Study.
Related Articles Breastmilk Feeding Practices Are Associated with the Co-Occurrence of Bacteria in Mothers' Milk and the Infant Gut: the CHILD Cohort Study. Cell Host Microbe. 2020 Jul 09;: Authors: Fehr K, Moossavi S, Sbihi H, Boutin RCT, Bode L, Robertson B, Yonemitsu C, Field CJ, Becker AB, Mandhane PJ, Sears MR, Khafipour E, Moraes TJ, Subbarao P, Finlay BB, Turvey SE, Azad MB Abstract Gut microbiota play a critical role in infant health....
Human physiology
Sun Jul 12, 2020 15:05
Pupil dilation as an indicator of future thinking.
Related Articles Pupil dilation as an indicator of future thinking. Neurol Sci. 2020 Jul 10;: Authors: El Haj M, Moustafa AA Abstract BACKGROUND: The pupil typically dilates in reaction to cognitive load. In this study, we, for the first time, investigated whether future thinking (i.e., the ability to generate hypothetical scenarios in the future) would result in pupil dilation. METHODS: We recorded pupil dilation of participants during...
Human physiology
Sun Jul 12, 2020 15:05
Are NHS dental practices socioeconomically distributed in Scotland, Wales and Northern Ireland?
Related Articles Are NHS dental practices socioeconomically distributed in Scotland, Wales and Northern Ireland? Br Dent J. 2020 Jul;229(1):40-46 Authors: Jo O, Kruger E, Tennant M Abstract Aim To investigate the relationship between deprivation and distance to NHS dental providers in Scotland, Wales and Northern Ireland.Methods A total of 1,795 NHS dental practices were located at the smallest geographic areas for Scotland, Wales and Northern...
Human physiology
Sun Jul 12, 2020 15:05
Glomerular endothelial cell heterogeneity in Alport syndrome.
Related Articles Glomerular endothelial cell heterogeneity in Alport syndrome. Sci Rep. 2020 Jul 10;10(1):11414 Authors: Soloyan H, Thornton M, Villani V, Khatchadourian P, Cravedi P, Angeletti A, Grubbs B, De Filippo R, Perin L, Sedrakyan S Abstract Glomerular endothelial cells (GEC) are a crucial component of the glomerular physiology and their damage contributes to the progression of chronic kidney diseases. How GEC affect the pathology of...
Human physiology
Sun Jul 12, 2020 15:05
Chemosensory mechanisms of host seeking and infectivity in skin-penetrating nematodes.
Related Articles Chemosensory mechanisms of host seeking and infectivity in skin-penetrating nematodes. Proc Natl Acad Sci U S A. 2020 Jul 10;: Authors: Gang SS, Castelletto ML, Yang E, Ruiz F, Brown TM, Bryant AS, Grant WN, Hallem EA Abstract Approximately 800 million people worldwide are infected with one or more species of skin-penetrating nematodes. These parasites persist in the environment as developmentally arrested third-stage infective...
Human physiology
Sun Jul 12, 2020 15:05
Obesity is Associated with Increased Basal and Postprandial β-Cell Insulin Secretion Even in the Absence of Insulin Resistance.
Related Articles Obesity is Associated with Increased Basal and Postprandial β-Cell Insulin Secretion Even in the Absence of Insulin Resistance. Diabetes. 2020 Jul 10;: Authors: van Vliet S, Koh HE, Patterson BW, Yoshino M, LaForest R, Gropler RJ, Klein S, Mittendorfer B Abstract We tested the hypothesis that obesity, independent of insulin resistance, is associated with increased insulin secretion. We compared insulin kinetics before and after...
Human physiology
Sun Jul 12, 2020 15:05
The immunogenetic diversity of the HLA system in Mexico correlates with underlying population genetic structure.
Related Articles The immunogenetic diversity of the HLA system in Mexico correlates with underlying population genetic structure. Hum Immunol. 2020 Jul 07;: Authors: Barquera R, Hernández-Zaragoza DI, Bravo-Acevedo A, Arrieta-Bolaños E, Clayton S, Acuña-Alonzo V, Martínez-Álvarez JC, López-Gil C, Adalid-Sáinz C, Vega-Martínez MDR, Escobedo-Ruíz A, Juárez-Cortés ED, Immel A, Pacheco-Ubaldo H, González-Medina L, Lona-Sánchez A, Lara-Riegos J, Sánchez-Fernández...
Human physiology
Sun Jul 12, 2020 15:05
The social nature of mitochondria: Implications for human health.
Related Articles The social nature of mitochondria: Implications for human health. Neurosci Biobehav Rev. 2020 Jul 08;: Authors: Picard M, Sandi C Abstract Sociality has profound evolutionary roots and is observed from unicellular organisms to multicellular animals. In line with the view that social principles apply across levels of biological complexity, a growing body of data highlights the remarkable social nature of mitochondria - life-sustaining...
Human physiology
Sun Jul 12, 2020 15:05
Advances in the Use of Neuromodulation for Neurogenic Dysphagia: Mechanisms and Therapeutic Application of Pharyngeal Electrical Stimulation, Transcranial Magnetic Stimulation, and Transcranial Direct Current Stimulation.
Related Articles Advances in the Use of Neuromodulation for Neurogenic Dysphagia: Mechanisms and Therapeutic Application of Pharyngeal Electrical Stimulation, Transcranial Magnetic Stimulation, and Transcranial Direct Current Stimulation. Am J Speech Lang Pathol. 2020 Jul 10;29(2S):1044-1064 Authors: Sasegbon A, Cheng I, Zhang M, Hamdy S Abstract Purpose The swallowing motor system and, specifically, its cortical substrates appear to have certain...
Human physiology
Sun Jul 12, 2020 15:05
Mitochondrial Alterations and Enhanced Human Leukocyte/Endothelial Cell Interactions in Type 1 Diabetes.
Related Articles Mitochondrial Alterations and Enhanced Human Leukocyte/Endothelial Cell Interactions in Type 1 Diabetes. J Clin Med. 2020 Jul 08;9(7): Authors: Iannantuoni F, M de Marañon A, Abad-Jiménez Z, Canet F, Díaz-Pozo P, López-Domènech S, Morillas C, Rocha M, Víctor VM Abstract Type 1 diabetes has been associated with oxidative stress. This study evaluates the rates of oxidative stress, mitochondrial function, leukocyte-endothelium...
Human physiology
Sun Jul 12, 2020 15:05
Effect of Human Attachment Style on Horse Behaviour and Physiology during Equine-Assisted Activities-A Pilot Study.
Related Articles Effect of Human Attachment Style on Horse Behaviour and Physiology during Equine-Assisted Activities-A Pilot Study. Animals (Basel). 2020 Jul 08;10(7): Authors: Arrazola A, Merkies K Abstract Equine-assisted activities (EAA) for human well-being and health rely on human-horse interactions for therapeutic effect. At-risk participants with mental and emotional difficulties can show poor social skills and functioning relationships,...
Human physiology
Sun Jul 12, 2020 15:05
human physiology; +95 new citations
95 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: human physiology These pubmed results were generated on 2020/07/11PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Human physiology
Sat Jul 11, 2020 14:59
human physiology; +119 new citations
119 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: human physiology These pubmed results were generated on 2020/07/10PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Human physiology
Fri Jul 10, 2020 14:54
medical science; +1013 new citations
1013 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: medical science These pubmed results were generated on 2020/07/12PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Medical Science
Sun Jul 12, 2020 17:18
medical science; +1013 new citations
1013 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: medical science These pubmed results were generated on 2020/07/12PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Medical Science
Sun Jul 12, 2020 13:18
medical science; +3020 new citations
3020 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: medical science These pubmed results were generated on 2020/07/11PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Medical Science
Sat Jul 11, 2020 17:21
medical science; +3020 new citations
3020 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: medical science These pubmed results were generated on 2020/07/11PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Medical Science
Sat Jul 11, 2020 13:22
medical science; +3011 new citations
3011 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: medical science These pubmed results were generated on 2020/07/10PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Medical Science
Fri Jul 10, 2020 17:23
medical science; +3011 new citations
3011 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: medical science These pubmed results were generated on 2020/07/10PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Medical Science
Fri Jul 10, 2020 13:24
How to destroy your friends and family in four popular board games
Mop the floor with your friends in games like Settlers of Catan. (Pixabay/)Whether it’s bankrupting your family in Monopoly or securing the last victory point against your buddies in Settlers of Catan, there’s nothing quite like the feeling of board-game triumph. We’ve collected experts’ best tips and tricks so you can dominate every time.MONOPOLYMost players forget the real goal of this game: It’s not to become rich. Instead, you must bankrupt your opponents before they wipe you out. Brian Valentine,...
Popular Science
01:00
Less roadkill during the pandemic could translate to more deer down the road
Deer collisions are down in several parts of the nation, including in California. (Ivana Cajina/)This story originally featured on Outdoor Life.Hunters know the risks of cruising down rural highways in whitetail country, and the deer carcasses lining our roadways are a not-so-subtle reminder. But during COVID-19 closures and social distancing, there has been a steep drop in the number of animals killed by vehicles.Roadkill animal deaths fell in California, Idaho, and Maine, according to a study by...
Popular Science
Sun Jul 12, 2020 00:00
How to carry just about anything on your bike
Turn to this guide when you really need to transport those wine bottles you turned into vases. (Sagar Rana / Unsplash/)Bikes seem like a fun, simple way to replace your daily commute—at least until you add some cargo to the equation. But bikes can pull their own weight. With a little know-how and the right accessories, your two-wheel ride will be able to handle a wide range of loads, from a light-but-bulky box to a month’s worth of groceries, and even a basket of your favorite furry friends.It’s...
Popular Science
Sat Jul 11, 2020 17:05
Behind the scenes of our summer cover, a working Rube Goldberg machine
A spinning, kicking, contraption of a cover. (The Voorhes/)Popular Science’s Play issue is now available to everyone. Read it now, no app or credit card required.The Rube Goldberg machine above is not the first that art and photography duo The Voorhes have created. But building one composed exclusively of playthings that fit on an 8-foot-by-8-foot bright-yellow wall while still leaving room for the text on the cover—that was a whole other challenge.The two started by looking at items featured in...
Popular Science
Sat Jul 11, 2020 01:00
Supreme Court ruling on birth control could have ripple effects beyond unwanted pregnancy
Between 70,500 and 126,400 people could lose access to contraception, according to government estimates. (Pixabay/)On July 8, the Supreme Court made it easier for employers to deny contraception coverage to their employees on religious or moral grounds.The Affordable Care Act mandates that employers must provide coverage for birth control at no out-of-pocket cost. Houses of worship are exempt from this requirement. Religiously affiliated organizations such as universities and hospitals, and some...
Popular Science
Fri Jul 10, 2020 23:02
Best electric bikes for getting around town or to work
Get by with a little help from your friend. (Tower Electric Bikes via Unsplash/)You’ve contemplated getting a bike to ride to work, but the sweat and those hills keep you from pulling the trigger. Lucky for you, eBikes with small motors are a great alternative. No more catching your breath up those steep streets or huffing and puffing pedaling 40 pounds of groceries. Here are some of our favorite eBikes under on the market today.Customize it. (Amazon/)This eBike comes with 21 gears, plus a brushless...
Popular Science
Fri Jul 10, 2020 22:59
Wedge pillows to help you find your ideal sleeping position
Snuggle up; it's going to be a sleepy ride. (Amazon/)Sleeping soundly each night can be difficult due to factors like stress levels, insomnia, and noise from traffic or neighbors. If you have GERD, sleep apnea, or chronic pain, it can be even more challenging to get your Zs. When you consult with your doctor about your condition and possible home treatments, ask them whether wedge pillows might help. These sleep aids are worth considering as part of any plan for quality rest and relaxation.Ramp up...
Popular Science
Fri Jul 10, 2020 22:38
Outdoor pizza ovens that will give you the best slices
Enjoy a quality slice outside. (Anastasiia Chepinska via Unsplash/)Sure, you have a grill in your backyard, but why not upgrade your set-up with an outdoor pizza oven? From compact to full-size, these outdoor pizza ovens will get that crust you dream of without leaving the house.Bring on the big boy. (Amazon/)You need an outdoor pizza oven that will stand up to your grill setup. This one is called ‘Thor,’ after the god of thunder, so you know it’s up to the task. This stainless steel setup includes...
Popular Science
Fri Jul 10, 2020 22:26
Surfers are riding a wave of new technologies to their Olympic debut
Riding waves is physically demanding, and preparing for competition requires intense cross-training that's being bettered by precise motion and muscle tracking. (Jake Marote/Red Bull/)Popular Science’s Play issue is now available to everyone. Read it now, no app or credit card required.One of the best surf spots in the United States to practice aerial tricks is in central Texas, some 200 miles from the Gulf Coast. On a brisk December day at the BSR Surf Resort, Caroline Marks was ripping a front-side...
Popular Science
Fri Jul 10, 2020 22:04
Why does laughing feel so stinkin’ good?
Let the giggles move through you. (John Devolle/)Popular Science’s Play issue is now available to everyone. Read it now, no app or credit card required.The oldest known joke dates back nearly 4,000 years, and it’s a fart gag. The fact that we’ve been crackin’ wise for so long suggests there’s something innate about the need to laugh. Heck—chimps, rats, and perhaps even dolphins do it. Neuroscientists and psychologists aren’t sure about the exact evolutionary reason for a chuckle, though its ability...
Popular Science
Fri Jul 10, 2020 21:20
Seven mistakes beginner cyclists make, and how to avoid them
Scenic rides are more fun when your bike fits and your skills are sharp. (Pixabay/)For many people, cycling started during childhood with handlebar streamers and training wheels. As we graduate from precariously practicing in parking lots on three-wheelers to roads and trails as adults, the potential for fun—and mistakes—grows. Here are some common mistakes beginners make when getting out into the world of two wheels.Choosing the wrong bikeFirst, ask yourself where you plan to ride. Will you be cruising...
Popular Science
Fri Jul 10, 2020 21:03
Automatic soap dispensers that are tough on germs and easy on the eyes
Keep them clean. (Matthew Tkocz via Unsplash/)Washing your hands is a must if you want to keep germs and bacteria away. It is recommended you wash up when coughing, blowing your nose, using the restroom, before and after eating, and much more. Elevate your germ-free game by getting yourself an automated soap dispenser, essentially eliminating contact with the bacteria that can live on bars and pump dispensers. Many of us associate automatic dispensers with airport, school, or gas station bathrooms...
Popular Science
Fri Jul 10, 2020 17:56
The best weed whackers for keeping your garden tidy
Keep your lawn in check. (Shaun Montero via Unsplash/)Lawn mowers are so closely correlated with cutting grass that it’s easy to forget about the frequently unsung yet equally important string trimmer. A string trimmer—commonly referred to as the “weed whacker”—is a touch-up tool of sorts that is just as capable at clearing large swaths of overgrowth as it is tackling the most delicate touch-ups around fences and posts. To put it simply, string trimmers go where lawn mowers can’t, and if you’re getting...
Popular Science
Fri Jul 10, 2020 17:37
The best paper filters for your coffee machine
Quality filters for your morning brew. (Tyler Nix via Unsplash/)No traditional drip coffee maker is complete without paper filters. They’re available in bulk, often at a wide variety of quantities depending on their features and the type of paper they’re made from. If you make multiple pots of joe a day, you might want to buy more filters at a time; if you put sustainability at the top of your priority list, a small-batch, natural paper option might be the way to go instead. Whichever type of paper...
Popular Science
Fri Jul 10, 2020 17:33
Masks help prevent the spread of the coronavirus—here’s a breakdown of how effective they are
Wearing a mask is one of the most important things you can do right now (Julian Wan/Unsplash/)Follow all of PopSci’s COVID-19 coverage here, including tips on cleaning groceries, ways to tell if your symptoms are just allergies, and a tutorial on making your own mask.Over the past several months, the idea of wearing a face covering has been hotly debated. In the beginning of the pandemic, the general recommendation was that masks should be reserved for medical professionals only. At the time, this...
Popular Science
Fri Jul 10, 2020 16:04
Effect of Dietary and Supplemental Lycopene on Cardiovascular Risk Factors: A Systematic Review and Meta-Analysis.
Related Articles Effect of Dietary and Supplemental Lycopene on Cardiovascular Risk Factors: A Systematic Review and Meta-Analysis. Adv Nutr. 2020 Jul 11;: Authors: Tierney AC, Rumble CE, Billings LM, George ES Abstract Cardiovascular disease (CVD) is the leading cause of death globally and the presence of ≥1 cardiovascular risk factors elevates total risk. Lycopene, a carotenoid with high antioxidant capacity, may be protective. The aim of...
pubmed: "adv nutr"[jour]
Sun Jul 12, 2020 14:20
Ecological Sensing Through Taste and Chemosensation Mediates Inflammation: A Biological Anthropological Approach.
Related Articles Ecological Sensing Through Taste and Chemosensation Mediates Inflammation: A Biological Anthropological Approach. Adv Nutr. 2020 Jul 10;: Authors: Giuliani C, Franceschi C, Luiselli D, Garagnani P, Ulijaszek S Abstract Ecological sensing and inflammation have evolved to ensure optima between organism survival and reproductive success in different and changing environments. At the molecular level, ecological sensing consists...
pubmed: "adv nutr"[jour]
Sat Jul 11, 2020 14:12
Escher-Trace: a web application for pathway-based visualization of stable isotope tracing data.
Related Articles Escher-Trace: a web application for pathway-based visualization of stable isotope tracing data. BMC Bioinformatics. 2020 Jul 10;21(1):297 Authors: Kumar A, Mitchener J, King ZA, Metallo CM Abstract BACKGROUND: Stable isotope tracing has become an invaluable tool for probing the metabolism of biological systems. However, data analysis and visualization from metabolic tracing studies often involve multiple software packages and...
pubmed: "bmc bioinformatics"...
Sun Jul 12, 2020 13:47
Leveraging Bayesian networks and information theory to learn risk factors for breast cancer metastasis.
Related Articles Leveraging Bayesian networks and information theory to learn risk factors for breast cancer metastasis. BMC Bioinformatics. 2020 Jul 10;21(1):298 Authors: Jiang X, Wells A, Brufsky A, Shetty D, Shajihan K, Neapolitan RE Abstract BACKGROUND: Even though we have established a few risk factors for metastatic breast cancer (MBC) through epidemiologic studies, these risk factors have not proven to be effective in predicting an individual's...
pubmed: "bmc bioinformatics"...
Sun Jul 12, 2020 13:47
Efficient implied alignment.
Related Articles Efficient implied alignment. BMC Bioinformatics. 2020 Jul 09;21(1):296 Authors: Washburn AJ, Wheeler WC Abstract BACKGROUND: Given a binary tree [Formula: see text] of n leaves, each leaf labeled by a string of length at most k, and a binary string alignment function ⊗, an implied alignment can be generated to describe the alignment of a dynamic homology for [Formula: see text]. This is done by first decorating each node of...
pubmed: "bmc bioinformatics"...
Sat Jul 11, 2020 13:21
Bioinformatics recipes: creating, executing and distributing reproducible data analysis workflows.
Related Articles Bioinformatics recipes: creating, executing and distributing reproducible data analysis workflows. BMC Bioinformatics. 2020 Jul 08;21(1):292 Authors: Aberra N, Sebastian A, Maloy AP, Rees CB, Bartron ML, Albert I Abstract BACKGROUND: Bioinformaticians collaborating with life scientists need software that allows them to involve their collaborators in the process of data analysis. RESULTS: We have developed a web application...
pubmed: "bmc bioinformatics"...
Fri Jul 10, 2020 16:59
HEnRY: a DZIF LIMS tool for the collection and documentation of biomaterials in multicentre studies.
Related Articles HEnRY: a DZIF LIMS tool for the collection and documentation of biomaterials in multicentre studies. BMC Bioinformatics. 2020 Jul 08;21(1):290 Authors: Heinen S, Schulze N, Franke B, Klein F, Lehmann C, Vehreschild MJGT, Gloistein C, Stecher M, Vehreschild JJ Abstract BACKGROUND: Well-characterized biomaterials of high quality have great potential for acceleration and quality improvement in translational biomedical research....
pubmed: "bmc bioinformatics"...
Fri Jul 10, 2020 16:59
Critique of the pairwise method for estimating qPCR amplification efficiency: beware of correlated data!
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pubmed: "bmc bioinformatics"...
Fri Jul 10, 2020 16:59
SOAPTyping: an open-source and cross-platform tool for sequence-based typing for HLA class I and II alleles.
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Fri Jul 10, 2020 16:59
SLFinder, a pipeline for the novel identification of splice-leader sequences: a good enough solution for a complex problem.
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Fri Jul 10, 2020 16:59

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