There is a concerningly high burden of potentially hazardous medical waste dumped in surgical changing rooms. We hope that the current study will raise awareness of the need for appropriate disposal of medical equipment before entering changing rooms and leads to formal evaluation and initiatives to mitigate medical waste and the associated cost in our healthcare system. Abstract Background Anecdotal evidence reveals that medical equipment are easily found in hospital changing rooms....
Fri Jul 10, 2020 22:55
Fri Jul 10, 2020 18:14
This study reviewed our experience on endovascular aortic repair for mycotic abdominal aortic aneurysm. Combined with potent antibiotic treatment and adjunctive drainage, reinfection rate was 18.8% with a median follow‐up time period of 41.2 months. It further indicated that endovascular aortic repair is a feasible and effective method for the treatment of mycotic abdominal aortic aneurysm. Abstract Background This study aimed to evaluate the feasibility and efficacy of endovascular...
Fri Jul 10, 2020 11:04
Abstract Aim Verification of the interrater reliability of axis I diagnoses of the German version of the DC/TMD. The hypothesis was that the DC/TMD protocol yields comparable results, if examiner instructions are closely followed. Material and Methods A culturally equivalent German translation of the DC/TMD was developed. During a one‐day calibration workshop at the University of Heidelberg, three examiners were trained by the DC/TMD Training and Calibration Center. According to the calibration...
Fri Jul 10, 2020 14:29
Journal of International Medical Research, Volume 48, Issue 7, July 2020. ObjectiveTo guide clinical decision making, race-, age- and gender-specific reference ranges for lymphocytes and CD4+ T-cell subsets are required.MethodsSingle platform flow cytometry to determine reference intervals for lymphocyte subpopulations and CD4+ T-cell subsets in 196 healthy Han Chinese adults.ResultsThe frequencies and absolute numbers of B cells were slightly lower in Han Chinese individuals of the Shanxi region...
Fri Jul 10, 2020 12:16
Journal of International Medical Research, Volume 48, Issue 7, July 2020. ObjectiveTo investigate the correlations between objective measurements and subjective evaluations of post-treatment facial attractiveness.MethodsTen orthodontists rated the subjective visual analog scale (VAS) scores of the facial profiles of 95 patients who had undergone orthodontic treatment. Post-treatment cephalograms and photographs were used. Eleven soft tissue measurements and eight maxillary incisor measurements were...
Thu Jul 09, 2020 08:30
Journal of International Medical Research, Volume 48, Issue 7, July 2020. ObjectiveThe CYP2C19 genetic variation may be involved in the development of atherosclerotic cardiovascular disease (ASCVD). Serum lipid levels are important risk factors for ASCVD, but the effect of the CYP2C19 gene on serum lipid metabolism remains unclear. This retrospective cohort study investigated the relationship between the CYP2C19 gene polymorphism and serum lipid levels in patients with ischemic stroke (IS).MethodsIS...
Thu Jul 09, 2020 08:25
Journal of International Medical Research, Volume 48, Issue 7, July 2020. BackgroundMediastinal myelolipoma is extremely rare. It is a benign nonfunctioning tumor composed of hematopoietic tissue and mature fatty tissue. Although computed tomography and magnetic resonance imaging are effective in diagnosing mediastinal myelolipoma, a definitive diagnosis is difficult to establish for rare extra-adrenal myelolipomas by imaging alone. Such tumors are often misdiagnosed as malignant retropleural liposarcoma,...
Thu Jul 09, 2020 08:12
Journal of International Medical Research, Volume 48, Issue 7, July 2020. ObjectiveTo develop a machine learning algorithm to identify cognitive dysfunction based on neuropsychological screening test results.MethodsThis retrospective study included 955 participants: 341 participants with dementia (dementia), 333 participants with mild cognitive impairment (MCI), and 341 participants who were cognitively healthy. All participants underwent evaluations including the Mini-Mental State Examination and...
Thu Jul 09, 2020 08:10
Journal of International Medical Research, Volume 48, Issue 7, July 2020. ObjectiveTo retrospectively investigate the epidemiological features, clinical manifestations and laboratory characteristics of bacteremic brucellosis.MethodsBrucellosis patients admitted to our clinic from January 2015 to December 2017 were included in the study. Patient electronic medical records were reviewed for epidemiological features, clinical manifestations, and laboratory findings.ResultsA total of 132 brucellosis...
Thu Jul 09, 2020 08:07
Journal of International Medical Research, Volume 48, Issue 7, July 2020. Aggressive angiomyxoma is an interstitial tumour that is often misdiagnosed and is likely to recur. There have been few reported cases of angiomyxoma in pregnant women. We report a case of a woman who was previously diagnosed with a tumour in her vulva that increased in size during both of her pregnancies and spontaneously decreased postpartum. Local excision was performed and a gonadotropin-releasing hormone agonist was administered....
Thu Jul 09, 2020 07:14
Journal of International Medical Research, Volume 48, Issue 7, July 2020. ObjectivesTo investigate whether dl-3-n-butylphthalide (NBP) affects cholinergic system function and ameliorates cognitive decline in a rat model of vascular dementia (VaD).MethodsThe VaD rat model was established by bilateral common carotid artery ligation (two-vessel occlusion, 2VO). Rats were divided into five groups: control, sham, 2VO, 2VO+NBP (80 mg/kg; intragastric), and 2VO+donepezil (1 mg/kg; intragastric). Treatments...
Thu Jul 09, 2020 07:11
Journal of International Medical Research, Volume 48, Issue 7, July 2020. Primary bone marrow diffuse large B cell lymphoma (DLBCL) is an independent pathologic type with a poor prognosis when treated with standard chemoimmunotherapy. Generally, rituximab-based high-dose chemotherapy regimens such as dose-adjusted etoposide, prednisone, vincristine, cyclophosphamide, and doxorubicin (DA-EPOCH) can be administered to young patients, followed by autologous stem cell transplantation. For elderly patients,...
Thu Jul 09, 2020 06:29
Journal of International Medical Research, Volume 48, Issue 7, July 2020. Impetigo herpetiformis is a rare variant of generalized pustular psoriasis that occurs during pregnancy or is triggered by pregnancy, often in association with hypocalcemia. This condition is associated with increased maternal and fetal morbidity and mortality. We report a 29-year-old pregnant woman who presented to hospital at the gestational age of 20 weeks with widespread erythema covered with pustules that coalesced to...
Thu Jul 09, 2020 05:24
Journal of International Medical Research, Volume 48, Issue 7, July 2020. ObjectivePulmonary microvascular endothelial cells (PMECs) exhibit specific responses in adaptation to hypoxia. However, the mechanisms regulating PMEC activities during hypoxia remain unclear. This study investigated the potential involvement of a microRNA, miR-375-3p, in the regulation of PMEC activities.MethodsPrimary PMECs were isolated from rats. The expression levels of miR-375-3p and Notch1 in the PMECs were detected...
Thu Jul 09, 2020 05:21
Journal of International Medical Research, Volume 48, Issue 7, July 2020. ObjectiveThis study aimed to evaluate the relationship between obstructive sleep apnea (OSA) and the fraction of exhaled nitric oxide (FENO), and to assess the effect of risk factors of airway inflammation on OSA.MethodsMedical records of patients in the Respiratory Sleep Center at Chao-Yang Hospital in Beijing between January 2015 and June 2017 were analyzed. All patients were diagnosed with OSA. Data of the medical history,...
Thu Jul 09, 2020 05:16
We reconstructed the brain cavity and inner ear of Velociraptor to better understand its lifestyle and hunting abilities. We found brain structures that are present in modern birds, indicating an exceptional sense of balance and agility. The inner ear also closely resembles that of flightless birds, and Velociraptor had a similar hearing ability to ravens. Velociraptor was an agile predator that relied heavily on its sense of hearing to hunt, although it would scavenge if given the opportunity....
Fri Jul 10, 2020 13:10
Abstract In accordance with Article 6 of Regulation (EC ) No 396/2005, the applicant Syngenta Crop Protection AG submitted a request to the competent national authority in the Netherlands to set an import tolerance for the active substance abamectin in various commodities imported from the United States of America. The data submitted in support of the request were found to be sufficient to derive MRL proposals for tree nuts, peaches, avocados, lettuces and salad plants, spinaches and similar leaves,...
Fri Jul 10, 2020 14:03
Abstract In accordance with Article 6 of Regulation (EC ) No 396/2005, the applicant Syngenta Agro GmbH submitted a request to the competent national authority in Germany to modify the existing maximum residue level (MRL ) for the active substance fludioxonil in elderberries in support of the intended NEU use. The data submitted in support of the request were found to be sufficient to derive an MRL proposal of 4 mg/kg for elderberries, as an extrapolation from red and black currants and blueberries....
Thu Jul 09, 2020 14:15
Abstract In accordance with Article 6 of Regulation (EC ) No 396/2005, the applicant LLG Sachsen‐Anhalt, Dez. Pflanzenschutz submitted a request to the competent national authority in Germany to modify the existing maximum residue levels (MRL s) for copper compounds in herbs and edible flowers. The data submitted in support of the request were found sufficient to derive an MRL proposal of 150 mg/kg, confirming the MRL proposal of the MRL review, for copper compounds in herbs and edible flowers...
Thu Jul 09, 2020 13:34
Abstract COVID‐19 has generated a global need for technologies that enable communication, collaboration, education and scientific discourse whilst maintaining physical distance. University closures due to COVID‐19 and physical distancing measures disrupt academic activities that previously occurred face‐to‐face. Restrictions placed on universities due to COVID‐19 have precluded most conventional forms of education, assessment, research and scientific discourse. Anatomists now require valid, robust...
Fri Jul 10, 2020 11:43
Abstract Purpose The quadriceps femoris (QF) consists of four muscles: the rectus femoris; vastus medialis; vastus lateralis, and vastus intermediate. The tendons of all of these parts join together into a single tendon that attaches to the patella. The QF is a powerful extensor of the knee joint that is needed for walking. A growing number of publications have examined the fifth head of the QF muscle. There is no information about the possibility of other heads, and there is no correct classification...
Thu Jul 09, 2020 18:53
Abstract Introduction The long thoracic nerve (LTN) has a risk of being damaged during chest surgery and should be considered when performing anesthesia such as a serratus anterior plane block (SAPB). We analyzed the relationship between landmarks—the fourth to ninth intercostal space (ICS) at the midaxillary line (MAL), through which the distal part of the LTN passes—and the LTN. Materials and Methods We used 25 specimens from 17 embalmed Korean cadavers. The MAL, level of rib and ICS,...
Thu Jul 09, 2020 18:20
Abstract Introduction The mandibular canal, as it was formerly named in Terminologia Anatomica (TA) , has also been called the inferior alveolar (nerve) canal in many scientific publications. This study was conducted to investigate how these terms have been understood in different regions and different areas of expertise and to discuss the appropriate future application of the term “mandibular canal.” Methods A literature search was conducted using PubMed, and articles using different terms...
Thu Jul 09, 2020 16:50
New England Journal of Medicine, Ahead of Print.
Fri Jul 10, 2020 07:06
New England Journal of Medicine, Ahead of Print.
Fri Jul 10, 2020 07:00
New England Journal of Medicine, Ahead of Print.
Fri Jul 10, 2020 07:00
New England Journal of Medicine, Ahead of Print.
Fri Jul 10, 2020 07:00
New England Journal of Medicine, Ahead of Print.
Fri Jul 10, 2020 07:00
Abstract During the past decade, new more targeted therapies for the treatment of atopic dermatitis (AD) have been developed and are currently under investigation in clinical trials.
Fri Jul 10, 2020 22:48
Abstract Background Group 2 innate lymphoid cells (ILC2) are stimulated by IL‐33 to increase IL‐5 and IL‐13 production and airway inflammation. While sex hormones regulate airway inflammation, it remained unclear if estrogen signaling through estrogen receptor‐α (ER‐α, Esr1 ) or ER‐β (Esr2 ) increased ILC2‐mediated airway inflammation. We hypothesize that estrogen signaling increases allergen‐induced IL‐33 release, ILC2 cytokine production, and airway inflammation. Methods Female Esr1‐/‐,...
Fri Jul 10, 2020 17:14
ABSTRACT Background Atopic dermatitis (AD) is associated with a dysregulation of the skin barrier and may predispose to the development of secondary allergic conditions, such as asthma. Tmem79ma/ma mice harbor mutations in the gene encoding Transmembrane Protein 79 (or Mattrin), which have previously been associated with AD. As a result of the Tmem79 gene mutation, these mice have a defective skin barrier and develop spontaneous skin inflammation. In this study Tmem79ma/ma mice were assessed...
Thu Jul 09, 2020 15:35
Abstract Near‐infrared spectroscopy (NIRS) has been proposed as a noninvasive modality for detecting complications in patients undergoing extracorporeal membrane oxygenation (ECMO), and it can simultaneously reveal the global circulatory status of these patients. We optimized ECMO therapy on the basis of real‐time peripheral NIRS probing. Three patients underwent venoarterial (VA) ECMO and one patient underwent venovenous (VV) ECMO. All patients received peripheral ECMO cannulation with routine...
Fri Jul 10, 2020 18:48
Abstract Optical coherence Doppler tomography (ODT) increasingly attracts attention because of its unprecedented advantages with respect to high contrast, capillary‐level resolution and flow speed quantification. However, the trade‐off between the signal‐to‐noise ratio (SNR) of ODT images and A‐scan sampling density significantly slows down the imaging speed, constraining its clinical applications. To accelerate ODT imaging, a deep‐learning‐based approach is proposed to suppress the overwhelming...
Fri Jul 10, 2020 16:24
Abstract The purpose of this study was to assess unique corneal tomographic parameters of allergic eye disease (AED) using optical coherence tomography (OCT) and artificial intelligence (AI). A total of 57 eyes diagnosed with AED were included. The curvature and aberrations of the air‐epithelium (A‐E) and epithelium‐Bowman's layer (E‐B) interfaces were calculated. Random forest AI models were built combing this data with the parameters of healthy, forme fruste keratoconus (FFKC) and KC eyes. The...
Fri Jul 10, 2020 16:04
Abstract Non‐linear optical imaging techniques have been widely used to reveal biological structures for accurate diagnosis at the cellular as well as the tissue level. In the present study, polarization‐dependent second‐harmonic generation (PSHG) was used to determine collagen orientation in breast cancer biopsy tissues (grades 0, I, II and III). The obtained data were processed using Fast Fourier Transform (FFT) analysis, while SHG anisotropy and the “ratio parameter” values were also calculated....
Thu Jul 09, 2020 12:42
Abstract Purpose of Review The aim of this review is as follows: (1) to present the role of otitis as a warning sign for inborn errors of immunity (IEI), (2) to establish which patients presenting otitis should be investigated for IEI, (3) to review data about main IEI associated with otitis-prone patients. Recent Findings Otitis media...
Sat Jul 11, 2020 03:00
Abstract Lung diffusion-weighted magnetic resonance imaging (DWI) has shown a promising value in lung lesion detection, diagnosis, differentiation, and staging. However, the respiratory and cardiac motion, blood flow, and lung hysteresis may contribute to the blurring, resulting in unclear lung images. The image blurring could adversely affect diagnosis performance. The purpose of this study is to reduce the DWI blurring and assess its positive effect on diagnosis. The retrospective...
Sat Jul 11, 2020 03:00
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