Related Articles Primary Intrathoracic Neurogenic Tumors: Clinical, Pathological, and Long-Term Outcomes. Thorac Cardiovasc Surg. 2020 Jul 11;: Authors: Galetta D, Spaggiari L Abstract BACKGROUND: Intrathoracic neurogenic tumors (INTs) are uncommon neoplasms arising from nerve tissues. We report our single-center experience in treating these rare INTs. METHODS: Using a prospective institutional database, clinical, surgical, and pathological...
Related Articles Sudden death by massive systemic embolism from cardiac myxoma. Role of the clinical autopsy and review of literature. Cardiovasc Pathol. 2020 May 23;49:107244 Authors: Dell'Aquila M, Carbone A, Pennacchia I, Stigliano E, Oliva A, Arena V Abstract Cardiac myxoma is a rare benign neoplasm of the heart. Historically myxomas were incidental findings during autopsies, however improved imaging techniques made these diagnosis possible...
Related Articles Pembrolizumab-induced severe oral mucositis in a patient with squamous cell carcinoma of the lung: A case study. Lung Cancer. 2020 Jun 30;147:21-25 Authors: Yoon SY, Han JJ, Baek SK, Kim HJ, Maeng CH Abstract BACKGROUND: Immune checkpoint inhibitors, such as pembrolizumab, a humanized monoclonal antibody against programmed death-1, elicit antitumor activity in various types of cancers, including lung cancer. However, pembrolizumab...
Related Articles Solid Tumor Metastases to the Pancreas Diagnosed Using Fine-Needle Aspiration. Am J Clin Pathol. 2020 Jul 11;: Authors: Hou T, Stewart JM, Lee JH, Gan Q Abstract OBJECTIVES: Solid tumor metastases to the pancreas are rare, and only limited literature on the topic is available. In this retrospective study, we reviewed 107 cases of solid tumor metastases to the pancreas diagnosed by fine-needle aspiration (FNA) from 2005 to 2019....
Related Articles Metastases of soft tissue sarcoma to the liver: A Historical Cohort Study from a Hospital-based Cancer Registry. Cancer Med. 2020 Jul 10;: Authors: Okamoto M, Matsuoka M, Soma T, Arai R, Kato H, Harabayashi T, Adachi H, Shinohara T, Sagawa T, Nishiyama N, Nambu T, Sakai W, Suzuki H, Kato H, Hiraga H Abstract BACKGROUND: Hepatic metastasis of soft tissue sarcoma is rare compared to lung metastasis, and the literature is scarce....
Related Articles Thyroid-Like Follicular Carcinoma of the Kidney With Low-Grade Sarcomatoid Component: A Hitherto Undescribed Case. Int J Surg Pathol. 2020 Jul 10;:1066896920940406 Authors: Rao V, Menon S, Bakshi G, Prakash G, Agarwal A, Desai S Abstract Thyroid-like follicular carcinoma of the kidney (TLFCK) is a rare subtype of renal cell carcinoma, which closely resembles follicular neoplasms of the thyroid and has a distinctive indolent...
Related Articles Conus Medullaris Teratoma: Case Report and Literature Review. Brain Tumor Res Treat. 2020 Jun 29;: Authors: Keykhosravi E, Tavallaii A, Rezaee H, Ebrahimzadeh K, Pishjoo M, Abdi R, Maftouh M, Aminzadeh B Abstract Teratomas are benign germ cell tumors that usually found out of their anatomical origin. Teratomas usually are found in sacrococcygeal area, gonads, mediastinum, cervicofacial region and intracranial fossa. Spinal teratomas...
Related Articles Congestive heart failure and upper extremity deep vein thrombosis: A rare presentation of a pheochromocytoma. J Taibah Univ Med Sci. 2020 Jun;15(3):244-248 Authors: Alfadhli EM Abstract Pheochromocytomas are rare catecholamine-secreting neoplasms, occurring in approximately 0.1-0.5% of the patients with hypertension. Typically, a pheochromocytoma presents with hypertension, a paroxysm of headaches, sweating, and palpitation....
Related Articles Evaluation of molecular subtypes and clonal selection during establishment of patient-derived tumor xenografts from gastric adenocarcinoma. Commun Biol. 2020 Jul 09;3(1):367 Authors: Peille AL, Vuaroqueaux V, Wong SS, Ting J, Klinger K, Zeitouni B, Landesfeind M, Kim WH, Lee HJ, Kong SH, Wulur I, Bray S, Bronsert P, Zanella N, Donoho G, Yang HK, Fiebig HH, Reinhard C, Aggarwal A Abstract Patient-derived xenografts (PDX) have...
Related Articles Next-generation sequencing demonstrates the rarity of short kinase variants specific to quadruple wild-type gastrointestinal stromal tumours. J Clin Pathol. 2020 Jul 09;: Authors: Wong NACS, Giger OT, Ten Hoopen R, Casey RT, Russell K, Faulkner C Abstract AIM: There is no known specific biomarker or genetic signal for quadruple wild-type (qWT) gastrointestinal stromal tumours (GISTs). By next-generation sequencing (NGS) of different...
Related Articles Unusual case of Paget disease of the nipple diagnosed by nipple scraping cytology. Dermatol Online J. 2020 Mar 15;26(3): Authors: Herbst E, Tismenetsky M, McIntosh VM Abstract Paget disease of the nipple is a rare presentation of breast cancer. It is sometimes mistaken for a benign skin condition of the nipple and surrounding areola, which can significantly delay the diagnosis and treatment. In over 90% of cases there is an...
Related Articles Eosinophilic dermatosis of hematologic malignancy: a case report. Dermatol Online J. 2020 Mar 15;26(3): Authors: Almeida FT, Caldas R, Rodrigues AP, Ferreira O, Brito C Abstract Eosinophilic dermatosis of hematologic malignancy (EDHM) is a dermatosis characterized by tissue eosinophilia that has been previously reported as insect bite-like reaction. It is a rare condition with a wide variety of clinical presentations ranging...
Related Articles Lichenoid inflammation of DSAP lesions following treatment with durvalumab, olaparib and paclitaxel: A potential diagnostic pitfall mimicking lichenoid drug eruptions associated with PDL-1 inhibitors. Dermatol Online J. 2020 Mar 15;26(3): Authors: Shakhbazova A, Hinds B, Marsch AF Abstract Disseminated superficial actinic porokeratosis (DSAP) is an uncommon skin condition that can be inherited or may occur sporadically with...
Related Articles A lumpy back: extensive cutaneous collagenomas. Dermatol Online J. 2020 Mar 15;26(3): Authors: Agosta D, Atzori L, Pilloni L, Brundu MA, Rongioletti F Abstract A widespread form of eruptive collagenomas in a 12-year-old man is presented for the impressive iconography, challenging differential diagnosis, and histopathological considerations associated with such rare connective tissue disorders. Syndromic forms should be carefully...
Related Articles Primary hepatic neuroendocrine carcinoma coexisting with distal cholangiocarcinoma: A case report and review of the literature. Medicine (Baltimore). 2020 Jun 26;99(26):e20854 Authors: Xin Q, Lv R, Lou C, Ma Z, Liu GQ, Zhang Q, Yu HB, Zhang CS Abstract INTRODUCTION: Although primary hepatic neuroendocrine carcinomas, whose prognostic mechanisms remain unclear, are rare, coexistence of neuroendocrine carcinomas and other tumors...
Related Articles Primary pulmonary extranodal natural killer/T-cell lymphoma (ENKTL), nasal type: Two case reports and literature review. Medicine (Baltimore). 2020 Jun 26;99(26):e20822 Authors: Hu Q, Xu L, Zhang X, Wang J, Zhou Z Abstract INTRODUCTION: Extranodal natural killer/T-cell lymphoma (ENKTL) - nasal type is an aggressive form of malignant non-Hodgkin lymphoma with a very poor prognosis. Especially primary pulmonary ENKTL is a relatively...
Related Articles Definitive radiation therapy in patients with unresectable desmoid tumors: a systematic review. Jpn J Clin Oncol. 2020 May 05;50(5):568-573 Authors: Matsunobu T, Kunisada T, Ozaki T, Iwamoto Y, Yoshida M, Nishida Y Abstract BACKGROUND: Desmoid tumors are rare soft tissue tumors. Wide local excision has been the standard surgical treatment for desmoid tumors. However, this procedure results in high local recurrence rates, so...
Related Articles A pooled analysis of primary hepatic angiosarcoma. Jpn J Clin Oncol. 2020 May 05;50(5):556-567 Authors: Zeng D, Cheng J, Gong Z, Chen J, Long H, Zhu B Abstract BACKGROUND: Angiosarcoma is an aggressive and malignant neoplasm. Primary hepatic angiosarcoma is extremely rare and accounts for only approximately 5% of all angiosarcomas. Therefore, many doctors do not know enough about this disease; this lack of knowledge motivated...
Related Articles Implantation and Monitoring by PET/CT of an Orthotopic Model of Human Pleural Mesothelioma in Athymic Mice. J Vis Exp. 2019 12 21;(154): Authors: Colin DJ, Bejuy O, Germain S, Triponez F, Serre-Beinier V Abstract Malignant pleural mesothelioma (MPM) is a rare and aggressive tumor arising in the mesothelium that covers the lungs, the heart, and the thoracic cavity. MPM development is mainly associated with asbestos. Treatments...
Related Articles Endoscopic Removal of Huge Cholesterol Granuloma in the Maxillary Sinus Confused With Odontogenic Keratocyst. J Craniofac Surg. 2020 Mar/Apr;31(2):507-509 Authors: Kim DJ, Kim SD, Kim SH, Cho KS Abstract Cholesterol granuloma is a foreign body reaction to the deposition of cholesterol crystals, usually found in association to chronic middle ear diseases, being highly uncommon in the paranasal sinuses. Furthermore, a huge and...
Related Articles Mini Osteoplastic Flap Through Supra-Eyebrow Incision for Primary Frontal Sinus Squamous Cell Carcinoma. J Craniofac Surg. 2020 Mar/Apr;31(2):517-519 Authors: Lee YM, Park HJ, Kim SD, Cho KS Abstract Primary carcinoma of the frontal sinus is very rare, with an incidence of 0.3% to 1.0% of all paranasal sinus carcinomas. Although complete resection with a clear margin is definitely essential to achieve tumor control, radical...
Related Articles Synbiotic fermented soymilk with Weissella cibaria FB069 and xylooligosaccharides prevents proliferation in human colon cancer cells. J Appl Microbiol. 2020 May;128(5):1486-1496 Authors: Le B, Ngoc APT, Yang SH Abstract AIM: Studies on the anticancer effects of synbiotic fermented soymilk are rare. The aim of the present study was to evaluate the effect of synbiotic fermented soymilk supplemented with xylooligosaccharides and...
Related Articles Evaluation of PD-L1 and PD-1 expression in aggressive eyelid sebaceous gland carcinoma and its clinical significance. Indian J Ophthalmol. 2019 12;67(12):1983-1987 Authors: Jayaraj P, Sen S Abstract Purpose: Eyelid sebaceous gland carcinoma (SGC) is an aggressive but rare malignancy of ocular region. Over-expression of PD-L1 and PD-1 has been demonstrated in a variety of solid tumors including conjunctival melanoma. PD-L1...
Related Articles Melanocytoma of the optic disk: A review. Indian J Ophthalmol. 2019 12;67(12):1949-1958 Authors: Shields JA, Demirci H, Mashayekhi A, Eagle RC, Shields CL Abstract Melanocytoma is a deeply pigmented variant of melanocytic nevus that classically occurs in the optic disk, sometimes with contiguous involvement of the adjacent retina or choroid. Historically, this tumor was often confused with malignant melanoma both clinically...
Related Articles A Rare Association With Obstructive Jaundice. Gastroenterology. 2020 04;158(5):e12-e13 Authors: Borges VP, Alves R, Coimbra J PMID: 31738922 [PubMed - indexed for MEDLINE]
Related Articles Extramammary Paget's Disease: A Review of the Literature Part II: Treatment and Prognosis. Dermatol Surg. 2020 03;46(3):305-311 Authors: Morris CR, Hurst EA Abstract BACKGROUND: Extramammary Paget's disease (EMPD) is a rare malignancy with unclear pathophysiology that occurs predominantly on apocrine-rich skin. Surgery is the treatment of choice; however, procedures tend to be extensive and associated with a high rate of recurrence....
Related Articles Primary Cutaneous Umbilical Melanoma: The Michigan Experience. Dermatol Surg. 2020 03;46(3):312-318 Authors: Charles KB, Chan MP, Smith NR, Orsini AP, Noh IK, Kozlow JH, Johnson TM, Cha KB Abstract BACKGROUND: Primary cutaneous umbilical melanoma is rare. Thorough information regarding its characteristics and treatment, including use of sentinel lymph node biopsy (SLNB) staging, is difficult to obtain. The unique anatomy of...
Related Articles Compound Heterozygous DOCK8 Mutations in a Patient with B Lymphoblastic Leukemia and EBV-Associated Diffuse Large B Cell Lymphoma. J Clin Immunol. 2019 08;39(6):592-595 Authors: Buchbinder D, Kirov I, Danielson J, Shah NN, Freeman AF, Chavan RS, Su HC Abstract Mutations in Dedicator of cytokinesis 8 (DOCK8) are a rare cause of combined immunodeficiency associated with atopy, infectious susceptibility, and risk for malignancy....
Related Articles Biphasic chest wall synovial sarcoma with epithelial pleural effusion: a diagnostic challenge. J Am Soc Cytopathol. 2019 Sep - Oct;8(5):293-298 Authors: Amer HZM, Ren R, Shen R Abstract Synovial sarcoma (SS) is a rare malignancy that most commonly involves the extremities and large joints. We describe a 67-year-old woman who presented with shortness of breath and flu-like symptoms, and a chest wall mass. On resection of the...
Related Articles Simultaneous occurrence of follicular and papillary thyroid carcinomas in same thyroid lobe: A case series of six patients from Qatar. Int J Surg Case Rep. 2020 Jun 20;73:65-70 Authors: Abdelaal A, El Ansari W, Abusabeib A, Farghaly H, Tabeb AAM Abstract BACKGROUND: Papillary thyroid carcinoma (PTC) and follicular thyroid carcinoma (FTC) are the first and second most common thyroid cancers comprising about 85% and 10% of all...
Related Articles Ex vivo assessment of targeted therapies in a rare metastatic epithelial-myoepithelial carcinoma. Neoplasia. 2020 Jul 06;22(9):390-398 Authors: Mäkelä R, Arjonen A, Suryo Rahmanto A, Härmä V, Lehtiö J, Kuopio T, Helleday T, Sangfelt O, Kononen J, Rantala JK Abstract Epithelial-myoepithelial carcinoma (EMC) is a rare subtype of salivary gland neoplasms. Since the initial description of the cancer, just over 300 cases have been...
Related Articles Synchronous Bilateral Lung Cancer With Discordant Histology. Oncology (Williston Park). 2020 Feb 20;34(2):55-60 Authors: Copur MS, Lackner R, Wedel W, Lintel N, Lintel MS, Gnatra K Abstract Synchronous multiple primary lung cancer (SMPLC) is a rare occurrence affecting 0.5% to 2% of patients with lung cancer. Synchronous discordant histology with small cell and non-small cell lung carcinoma is an even less common entity. There...
Related Articles Metastatic Plasmacytoid Bladder Cancer Harboring a CDH-1 Mutation and Producing High Levels of CA 19-9. A Case Report and Literature Review. Am J Case Rep. 2020 Jul 09;21:e923130 Authors: Telfah M, Parikh RA, Zhang D, Kasi A Abstract BACKGROUND Plasmacytoid urothelial carcinoma (PUC) is a rare and aggressive variant of urothelial cancers. Herein, we report a patient with CDH-1 mutated PUC who presented with disseminated peritoneal...
Related Articles Langerhans cell sarcoma involving skin and showing epidermotropism: a comprehensive review. J Cutan Pathol. 2020 Jul 09;: Authors: Ronen S, Keiser E, Collins KM, Aung PP, Nagarajan P, Tetzlaff MT, Curry JL, Ivan D, Prieto VG, Hymes S, Medeiros LJ, Torres-Cabala CA Abstract Langerhans cell sarcoma (LCS) is rare and aggressive and patients have an overall survival rate of less than 50%. We present a 62-year old man with a history...
Related Articles Atypical Cells on Reflectance Confocal Microscopy May Not Represent Melanoma: A Case of Axillary Pigmented Extramammary Paget Disease. J Cutan Pathol. 2020 Jul 09;: Authors: Chuchvara N, Reilly C, Haroon A, Wassef C, Maghari A, Rao B Abstract Pigmented extramammary Paget disease (PEMPD) is a rare intraepithelial carcinoma which can clinically resemble other pigmented neoplasms. Similarities to melanoma on dermoscopy, histopathology,...
Related Articles Dual BRAF/MEK blockade restores CNS responses in BRAF-mutant Erdheim-Chester disease patients following BRAF inhibitor monotherapy. Neurooncol Adv. 2020 Jan-Dec;2(1):vdaa024 Authors: Mazor RD, Weissman R, Luckman J, Domachevsky L, Diamond EL, Abdel-Wahab O, Shapira S, Hershkovitz-Rokah O, Groshar D, Shpilberg O Abstract Background: Erdheim-Chester disease (ECD), a rare inflammatory myeloid neoplasm, is known to be fundamentally...
Related Articles NCI-CONNECT: Comprehensive Oncology Network Evaluating Rare CNS Tumors-Histone Mutated Midline Glioma Workshop Proceedings. Neurooncol Adv. 2020 Jan-Dec;2(1):vdaa007 Authors: Theeler BJ, Dalal Y, Monje M, Shilatifard A, Suvà ML, Aboud O, Camphausen K, Cordova C, Finch E, Heiss JD, Packer RJ, Romo CG, Aldape K, Penas-Prado M, Armstrong T, Gilbert MR Abstract Histone mutations occur in approximately 4% of different cancer types....
Related Articles Constitutional mismatch repair deficiency-associated brain tumors: report from the European C4CMMRD consortium. Neurooncol Adv. 2019 May-Dec;1(1):vdz033 Authors: Guerrini-Rousseau L, Varlet P, Colas C, Andreiuolo F, Bourdeaut F, Dahan K, Devalck C, Faure-Conter C, Genuardi M, Goldberg Y, Kuhlen M, Moalla S, Opocher E, Perez-Alonso V, Sehested A, Slavc I, Unger S, Wimmer K, Grill J, Brugières L Abstract Background: Malignant...
Related Articles Malignant Melanoma of the Female Genital Tract: Experience of an Oncology Center in Pakistan. Cureus. 2020 Jun 07;12(6):e8484 Authors: Shakeel O, Ullah F, Khalid N, Ali SI, Batool S, Amjad A, Anwer AW, Ali H, Zafar H, Syed AA Abstract Introduction Malignant melanoma, which arises from melanocytes or pigment cells, is one of the most common forms of epithelial cancer. Cutaneous and noncutaneous melanomas differ clinically and...
Related Articles Risk of Liver Cirrhosis and Hepatocellular Carcinoma after Fontan Operation: A Need for Surveillance. Cancers (Basel). 2020 Jul 06;12(7): Authors: Yoon JS, Lee DH, Cho EJ, Song MK, Choi YH, Kim GB, Lee YB, Lee JH, Yu SJ, Kim H, Kim YJ, Yoon JH, Bae EJ Abstract Liver cirrhosis and hepatocellular carcinoma (HCC) are serious late complications that can occur after the Fontan procedure. This study aimed to investigate the cumulative...
Related Articles Testing for ROS1, ALK, MET, and HER2 rearrangements and amplifications in a large series of biliary tract adenocarcinomas. Virchows Arch. 2020 Jul;477(1):33-45 Authors: Augustin J, Gabignon C, Scriva A, Menu L, Calmel C, Scatton O, Paye F, Fléjou JF, Praz F, Cervera P, Wendum D Abstract Biliary tract carcinomas are divided into intrahepatic, perihilar, distal extrahepatic cholangiocarcinomas, and gallbladder adenocarcinomas....
Related Articles Rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisolone combined with high-dose methotrexate plus intrathecal chemotherapy for newly diagnosed intravascular large B-cell lymphoma (PRIMEUR-IVL): a multicentre, single-arm, phase 2 trial. Lancet Oncol. 2020 04;21(4):593-602 Authors: Shimada K, Yamaguchi M, Atsuta Y, Matsue K, Sato K, Kusumoto S, Nagai H, Takizawa J, Fukuhara N, Nagafuji K, Miyazaki K, Ohtsuka E, Okamoto M, Sugita...
Related Articles A Rare Case of a Pediatric Medullary Intracranial Germinoma. World Neurosurg. 2020 06;138:137-140 Authors: Seifert K, Huttner A, Malhotra A Abstract BACKGROUND: Germinomas are rare intracranial lesions, with medulla germinomas being reported in only approximately 20 cases to date. These tumors are extremely sensitive to radiotherapy, and knowledge of them can allow for accurate diagnosis as well as significantly impact treatment...
Related Articles Pituitary Apoplexy Accompanying Temporal Lobe Seizure as a Complication. World Neurosurg. 2020 06;138:153-157 Authors: Shijo K, Yoshimura S, Mori F, Yamamuro S, Sumi K, Oshima H, Yoshino A Abstract BACKGROUND: Pituitary apoplexy is an acute clinical syndrome caused by infarction and/or hemorrhage of pituitary adenoma, which typically presents with severe headache, visual deterioration, and endocrine abnormalities. However,...
Related Articles Improvement of Hemichorea Following Surgical Resection of a Putaminal Cavernous Angioma: Case Report and Review of Literature. World Neurosurg. 2020 06;138:125-128 Authors: Ruschel LG, Brock RS, Teles Gomes MQ, Vellutini EAS, Oliveira MF Abstract BACKGROUND: Hemichorea may point to a structural lesion in the contralateral basal ganglia with a large list of possible causes. Cavernous angioma may be rarely a possible cause for...
Related Articles Primary Intracranial Angioleiomyoma: A Case Report and Literature Review. World Neurosurg. 2020 06;138:145-152 Authors: Chen F, Pan Y, Teng Y, Pan X, Yu Y Abstract BACKGROUND: Angioleiomyoma is a benign soft tissue tumor that manifests as pain and is more common in the extremities. However, primary intracranial angioleiomyoma is an extremely rare entity that is poorly characterized clinically, radiologically, and histopathologically....
Related Articles Jejunal metastasis of Merkel cell carcinoma: case report. G Chir. 2019 Jul-Aug;40(4):364-367 Authors: Mancini S, Solinas L, Leone L, Battaglia B, Notarangelo MG, Hassan R, Di Cosimo C, Angeloni R, Belardi A, Cosentino L, Bakacs A, Sagnotta A Abstract Merkel cell carcinoma (MCC) of the skin is a rare but aggressive cutaneous neuroendocrine-derived malignancy that predominantly affects elderly white males. The presence of distant...
Related Articles A rare case of trichilemmal ovarian carcinoma. Case report and review of the literature. G Chir. 2019 Jul-Aug;40(4):334-337 Authors: Leanza V, Nobile V, Galvagno C, Di Grazia FM, Palumbo M, Leanza G Abstract Trichilemmal ovarian carcinoma is very rare. A 52-years-old woman was admitted to University Hospital Department suffering from pain in the left iliaca fossa lasting for three months. Uterus was normal in size, painless...
Related Articles Nuck canal cyst involving right femoral vein: management and therapy of a rare clinical case. G Chir. 2019 Jul-Aug;40(4):318-321 Authors: Leanza V, D'Antoni S, Lo Presti V, Zanghì G, Vecchio R, Leanza G, Basile F Abstract We present a very rare case of a 49-year old woman suffering from Nuck canal cyst reaching and compressing femoral vein. Nuck canal cyst is very uncommon event because the pouch accompanying the gubernaculum...
Related Articles Non small cell lung cancer metastasized to the breast and treated with modified radical mastectomy: a case report. G Chir. 2019 Jul-Aug;40(4):304-307 Authors: Grigoropoulos P, Mariolis-Sapsakos T, Karantonis I, Kaklamanos I, Karanasiou V, Zografos CG, Chrysikos D Abstract Breast metastasis from extra-mammary malignancy is extremely rare with an incidence from 0.4% to 1.3%. Several types of malignancies that most commonly metastasize...
Related Articles Flying with Colloid Cyst: A Cautionary Note. World Neurosurg. 2020 06;138:84-88 Authors: Kutty RK, Sreemathyamma SB, Sivanandapanicker JL, Asher P, Peethambaran A Abstract BACKGROUND: Colloid cysts are benign and rare tumors of the brain. The growth rates of these tumors are unpredictable. These cysts can increase in size and obstruct the cerebrospinal fluid pathways producing obstructive hydrocephalus. Consequently, this can...
Related Articles Ketogenic diets in medical oncology: a systematic review with focus on clinical outcomes. Med Oncol. 2020 Jan 11;37(2):14 Authors: Klement RJ, Brehm N, Sweeney RA Abstract Preclinical data provide evidence for synergism between ketogenic diets (KDs) and other oncological therapies. The aim of this systematic review was to summarize data from clinical studies that have tested KDs along with other treatments used within medical...
Related Articles Surgical treatment of cyst of the canal of Nuck and prevention of lymphatic complications: A single-center experience. Lymphology. 2019;52(3):143-148 Authors: Cornacchia C, Dessalvi S, Boccardo F Abstract The canal of Nuck is a residue of the peritoneal evagination that runs along the round ligament through the inguinal canal in women. Its partial or total patency can lead to a cystic lymphangioma (CL). CL of the canal of Nuck...
Related Articles Overlapping autoimmune syndrome: A case of concomitant anti-NMDAR encephalitis and myelin oligodendrocyte glycoprotein (MOG) antibody disease. J Neuroimmunol. 2020 02 15;339:577124 Authors: Pérez CA, Agyei P, Gogia B, Harrison R, Samudralwar R Abstract Anti-N-methyl-d-aspartate receptor (NMDAR) encephalitis is an autoimmune disorder of the central nervous system that commonly manifests as a complex neuropsychiatric syndrome....
Related Articles Emerging strategies in peripheral T-cell lymphoma. Hematology Am Soc Hematol Educ Program. 2019 12 06;2019(1):41-46 Authors: Mehta-Shah N Abstract Peripheral T-cell lymphomas (PTCLs) are a heterogenous group of aggressive non-Hodgkin lymphomas that are less chemosensitive than their B-cell counterparts. Until recently, standard therapy did not distinguish between subtypes, and deeper understanding of the biology of these diseases...
Related Articles Undifferentiated intimal sarcoma mimicking a mycotic aneurysm. Vasa. 2020 Apr;49(3):243-246 Authors: Seo H, Hirai H, Aoyama T, Suehiro Y, Kubota Y, Suehiro S Abstract Intimal sarcoma of arteries is a rare malignant tumor, which often mimics other vascular disorders; therefore, preoperative diagnosis is often challenging. We herein report a 71-year-old man who presented with fever and elevated inflammatory markers who had a...
Related Articles Primary Bone Tumors: Challenges and Opportunities for CAR-T Therapies. J Bone Miner Res. 2019 10;34(10):1780-1788 Authors: Folkert IW, Devalaraja S, Linette GP, Weber K, Haldar M Abstract Primary malignant bone tumors are rare, occur in all age groups, and include distinct entities such as osteosarcoma, Ewing sarcoma, and chondrosarcoma. Traditional treatment with some combination of chemotherapy, surgery, and radiation has...
Related Articles Loss of the PTCH1 tumor suppressor defines a new subset of plexiform fibromyxoma. J Transl Med. 2019 07 30;17(1):246 Authors: Banerjee S, Corless CL, Miettinen MM, Noh S, Ustoy R, Davis JL, Tang CM, Yebra M, Burgoyne AM, Sicklick JK Abstract BACKGROUND: Plexiform fibromyxoma (PF) is a rare gastric tumor often confused with gastrointestinal stromal tumor. These so-called "benign" tumors often present with upper GI bleeding...
Related Articles An unexpected cause of dysphagia: pleural mesothelioma. Rev Esp Enferm Dig. 2019 06;111(6):494-495 Authors: Santos Seoane SM, Yano Escudero R, Arenas García V Abstract Malignant mesothelioma usually originates from the pleura or peritoneum, and has a poor prognosis. The incidence of this type of tumor is increasing worldwide, which is probably a result of occupational or environmental exposure to asbestos. In 90% dyspnea, chest...
Related Articles Miniprobe endoscopic ultrasonography for the diagnosis of colon hemangiolymphangioma. Rev Esp Enferm Dig. 2019 Jun;111(6):488-490 Authors: Castro-Poças FM, Bernardo S, Lima OMG, Santos MD Abstract Hemangiolymphangioma is a very rare benign vascular tumor that affects the gastrointestinal tract in less than 1% of cases. We present the case of an asymptomatic 52-year-old female referred for endoscopic colorectal cancer screening....
Related Articles A rare lymphoproliferative disorder associated with immunomodulating therapy in Crohn's disease. Rev Esp Enferm Dig. 2019 06;111(6):491 Authors: López Fernández E, Curieses Luengo M, Varela Trastoy P Abstract Lymphomatoid granulomatosis is a rare lymphoproliferative disorder associated with immunosuppressive therapy in inflammatory bowel disease. We present the case of a patient with Crohn's disease and treated azathioprine...
Related Articles Clinical Characteristics and Prognostic Factors of Patients with Intrahepatic Cholangiocarcinoma with Fever: A Propensity Score Matching Analysis. Oncologist. 2019 07;24(7):997-1007 Authors: Gong ZJ, Cheng JW, Gao PT, Huang A, Sun YF, Zhou KQ, Hu B, Qiu SJ, Zhou J, Fan J, Yang XR Abstract BACKGROUND: Patients with intrahepatic cholangiocarcinoma (ICC) rarely present fever as the initial symptom. We aimed to identify clinical...
Related Articles Papillary glioneuronal tumor (PGNT) exhibits a characteristic methylation profile and fusions involving PRKCA. Acta Neuropathol. 2019 05;137(5):837-846 Authors: Hou Y, Pinheiro J, Sahm F, Reuss DE, Schrimpf D, Stichel D, Casalini B, Koelsche C, Sievers P, Wefers AK, Reinhardt A, Ebrahimi A, Fernández-Klett F, Pusch S, Meier J, Schweizer L, Paulus W, Prinz M, Hartmann C, Plate KH, Reifenberger G, Pietsch T, Varlet P, Pagès M, Schüller U, Scheie...
Related Articles Brain Metastases and Place of Antiangiogenic Therapies in Alveolar Soft Part Sarcoma: A Retrospective Analysis of the French Sarcoma Group. Oncologist. 2019 07;24(7):980-988 Authors: Malouf GG, Beinse G, Adam J, Mir O, Chamseddine AN, Terrier P, Honore C, Spano JP, Italiano A, Kurtz JE, Coindre JM, Blay JY, Le Cesne A Abstract BACKGROUND: Alveolar soft part sarcoma (ASPS) is a rare sarcoma characterized by a slow evolution,...
Related Articles BRCA1/2 Functional Loss Defines a Targetable Subset in Leiomyosarcoma. Oncologist. 2019 07;24(7):973-979 Authors: Seligson ND, Kautto EA, Passen EN, Stets C, Toland AE, Millis SZ, Meyer CF, Hays JL, Chen JL Abstract BACKGROUND: Soft-tissue sarcomas (STS) describe a heterogeneous group of mesenchymal tumors with limited treatment options. Targeted therapies exist for BRCA1/2 gene alterations, but their prevalence and role have...
Related Articles High-Grade Gastrointestinal Neuroendocrine Carcinoma Management and Outcomes: A National Cancer Database Study. Oncologist. 2019 07;24(7):911-920 Authors: Alese OB, Jiang R, Shaib W, Wu C, Akce M, Behera M, El-Rayes BF Abstract BACKGROUND: High-grade neuroendocrine carcinomas are rare in the gastrointestinal tract. However, treatment patterns and outcomes have not been well described. SUBJECTS, MATERIALS, AND METHODS:...
Related Articles StatPearls Book. 2020 01 Authors: Abstract Germ cell tumors (GCT), derived from primordial germ cells, are a diverse group of neoplasms that arise in the gonads (testicles and ovaries) primarily and may also arise in the anterior mediastinum, pineal gland, and brain. They are clinically classified into two major categories, with significant clinical and prognostic implications: Seminomas and non-seminomas. Seminomas generally have a good prognosis,...
Related Articles StatPearls Book. 2020 01 Authors: Abstract Primary vaginal cancer is rare, making up 1% to 2% of all female reproductive tract cancers.[1] The vagina is a unique organ with distinct tissue types and planes. It is a 7 to 10 cm long fibromuscular tube extending from the cervix to the vulva. It sits posterior to the urethra and bladder and anterior to the rectum. The organ is divided into three parts, which are important for classifying tumor location...
Related Articles StatPearls Book. 2020 01 Authors: Abstract The most common type of cancer arising in the kidney is renal cell carcinoma (aka hypernephroma or Grawitz tumor), making up more than 9 out of 10 renal cancers in adults. Other types include transitional cell carcinomas of the renal pelvis, which behave like bladder cancers. Renal sarcoma is another rare tumor of the kidney. This review will focus mainly on renal cell carcinoma (RCC), which accounts...
Related Articles StatPearls Book. 2020 01 Authors: Abstract Testicular cancer is an uncommon malignancy of the males. It is divided into germ-cell tumors and sex cord-stromal tumors. Germ cell tumors are the commonest type, accounting for about 95% of testicular malignancies. Germ cell tumors are further divided into seminomatous and non-seminomatous. The rare sex cord-stromal tumors account for about 5% of testicular cancers. A Leydig tumor is the commonest variant. Testicular...
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