Related Articles Distinct Phenotypes of Islet Antigen-specific CD4+ T Cells among the Three Subtypes of Type 1 Diabetes. J Clin Endocrinol Metab. 2020 Jul 11;: Authors: Chujo D, Kawabe A, Matsushita M, Takahashi N, Tsutsumi C, Haseda F, Imagawa A, Hanafusa T, Ueki K, Kajio H, Yagi K, Tobe K, Shimoda M Abstract CONTEXT: Type 1 diabetes (T1D) is classified into three subtypes: acute onset (AT1D), slowly progressive (SP1D), and fulminant (FT1D)....
Related Articles The immune profile of pituitary adenomas and a novel immune classification for predicting immunotherapy responsiveness. J Clin Endocrinol Metab. 2020 Jul 12;: Authors: Wang Z, Guo X, Gao L, Deng K, Lian W, Bao X, Feng M, Duan L, Zhu H, Xing B Abstract CONTEXT: The tumor immune microenvironment is associated with clinical outcomes and immunotherapy responsiveness. OBJECTIVE: To investigate the intratumoral immune profile...
Related Articles A Genomewide Pharmacogenetic Study of Growth Hormone Responsiveness. J Clin Endocrinol Metab. 2020 Jul 11;: Authors: Dauber A, Meng Y, Audi L, Vedantam S, Weaver B, Carrascosa A, Albertsson-Wikland K, Ranke MB, Jorge AAL, Cara J, Wajnrajch MP, Lindberg A, Camacho-Hübner C, Hirschhorn JN Abstract CONTEXT: Individual patients vary in their response to growth hormone (GH). No large scale genomewide studies have looked for genetic...
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23 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: American Journal of Cancer Research These pubmed results were generated on 2020/07/10PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
23 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: American Journal of Cancer Research These pubmed results were generated on 2020/07/10PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
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Related Articles Histologic and Cost-Benefit Analysis of Laparoscopic Sleeve Gastrectomy Specimens Performed for Morbid Obesity. Arch Pathol Lab Med. 2020 Jul 10;: Authors: Nowak K, Di Palma A, Chieu K, Quereshy F, Jackson T, Okrainec A, Serra S, Chetty R Abstract CONTEXT.—: Laparoscopic sleeve gastrectomy (LSG) has quickly become the bariatric surgical procedure of choice for patients with obesity who have failed medical management. Laparoscopic...
Sat Jul 11, 2020 17:02
Related Articles Commercial SARS-CoV-2 Molecular Assays: Superior Analytical Sensitivity of cobas SARS-CoV-2 Relative to NxTAG Cov Extended Panel and ID NOW COVID-19 Test. Arch Pathol Lab Med. 2020 Jul 10;: Authors: Jin R, Pettengill MA, Hartnett NL, Auerbach HE, Peiper SC, Wang Z Abstract Context - We implemented multiple nucleic acid amplification test platforms because of the limited availability of test kits for severe acute respiratory...
Sat Jul 11, 2020 17:02
A comprehensive appraisal of laboratory biochemistry tests as major predictors of COVID-19 severity.
Related Articles A comprehensive appraisal of laboratory biochemistry tests as major predictors of COVID-19 severity. Arch Pathol Lab Med. 2020 Jul 10;: Authors: Aloisio E, Chibireva M, Serafini L, Pasqualetti S, Falvella FS, Dolci A, Panteghini M Abstract Context: A relevant portion of COVID-19 patients develop severe disease with negative outcomes. Several biomarkers have been proposed to predict COVID-19 severity, but no definite interpretative...
Sat Jul 11, 2020 17:02
Related Articles HER2 Testing in Endometrial Serous Carcinoma. Arch Pathol Lab Med. 2020 Jul 10;: Authors: Buza N Abstract CONTEXT.—: Endometrial serous carcinoma is an aggressive subtype of endometrial cancer with the highest rate of recurrence and mortality among all histotypes. A recent clinical trial showed prolonged progression-free survival in advanced-stage and recurrent human epidermal growth factor receptor 2 (HER2)-positive endometrial...
Sat Jul 11, 2020 17:02
Related Articles Clinical, Operative, and Economic Outcomes of the Point-of-Care Blood Gases in the Nephrology Department of a Third-Level Hospital. Arch Pathol Lab Med. 2020 Jul 10;: Authors: Qasem Moreno AL, Sáez PO, Calle PF, Del Peso Gilsanz G, Ramos SA, Almirón MD, Soto AB Abstract CONTEXT.—: Point-of-care testing allows rapid analysis and short turnaround times. To the best of our knowledge, the present study assesses, for the first...
Sat Jul 11, 2020 17:02
Related Articles Mounting a Regional Response to the COVID-19 Pandemic: Another Reason to "Keep" Your Lab. Arch Pathol Lab Med. 2020 Jul 10;: Authors: Paczos TA Abstract Context: Declining reimbursement shifts hospital laboratories from system assets to cost centers. This has resulted in increased outsourcing of laboratory services which can jeopardize a hospital systems ability to respond to a health care crisis. Objectives: To demonstrate...
Sat Jul 11, 2020 17:02
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Related Articles Secondhand Tobacco Smoke Exposure in Indoor Workplaces in Viet Nam and Associated Factors: Findings from Two Rounds of Global Adult Tobacco Surveys (GATS) 2010 and 2015. Asian Pac J Cancer Prev. 2020 Jul 01;21(S1):33-38 Authors: Lam NT, Nga PTQ, Kashiwabara M, Hai PT, Huyen DTT, Giang KB, Minh HV, Quan NT, Khue LN, Park K Abstract OBJECTIVES: This paper explores changes in the level of secondhand smoke (SHS) exposure at indoor...
Related Articles Raising Tobacco Taxes: The Philippine Experience. Asian Pac J Cancer Prev. 2020 Jul 01;21(S1):27-31 Authors: Diosana JL Abstract The 2012 Philippine Sin Tax Reform Law or Republic Act No. 10351 (RA10351) offers important lessons on tobacco taxation and tobacco control. In a span of five years, it increased the excise tax rate on cigarettes to as high as 1000% for low-priced brands. It is recognized by the international community...
Related Articles Tobacco Industry Fingerprints on Delaying Implementation of Pictorial Health Warnings in the Western Pacific. Asian Pac J Cancer Prev. 2020 Jul 01;21(S1):23-25 Authors: Tan YL, Mackay J, Kolandai MA, Dorotheo EU Abstract OBJECTIVE: This case series describes tobacco industry tactics and strategies used to interfere, derail, delay, and weaken the development of effective health warning regulations in Malaysia, Cambodia, the Philippines,...
Related Articles Secondhand Smoke Exposure among Nonsmokers in China. Asian Pac J Cancer Prev. 2020 Jul 01;21(S1):17-22 Authors: Xiao L, Jiang Y, Zhang J, Parascandola M Abstract BACKGROUND: China signed the World Health Organization Framework Convention on Tobacco Control and conducted a series of activities to protect people from secondhand smoke exposure. This paper explores the changes in prevalence of secondhand smoke exposure among nonsmokers...
Related Articles Investing in Tobacco Control: Twelve Years of MPOWER Measures and Progress in the Western Pacific Region. Asian Pac J Cancer Prev. 2020 Jul 01;21(S1):9-16 Authors: De Pinho Campos K, Kashiwabara M, Teakle A, De Guzman R, Lannan K, Mercado S Abstract Tobacco use has detrimental effects in the Western Pacific Region. The World Health Organization (WHO) Framework Convention on Tobacco Control (FCTC) came into effect in 2005 to...
Related Articles Improving Information to Enable Effective Tobacco Control Intervention and Measure Progress Over Time: The Cambodia Country Experience. Asian Pac J Cancer Prev. 2020 Jul 01;21(S1):5-8 Authors: Rarick J, Kheam T, Daravuth Y, Tursan D'Espaignet E, Kashiwabara M, Chhordaphea C, Ritthiphakdee B Abstract Tobacco is a leading cause of noncommunicable diseases (NCDs) which kill about 41 million people each year. Of these, 15 million...
Related Articles Making Strides Together against Tobacco Use. Asian Pac J Cancer Prev. 2020 Jul 01;21(S1):3 Authors: Kasai T Abstract In the Western Pacific Region, more than 3 million people die each year as a result of tobacco use - a problem for health and a threat to social and economic development. Countries around the world made a commitment by adopting the WHO Framework Convention on Tobacco Control of which implementation was then further...
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Related Articles Occurrence and number of immune-related adverse events are independently associated with survival in advanced non-small-cell lung cancer treated by nivolumab. Bull Cancer. 2020 Jul 06;: Authors: Bouhlel L, Doyen J, Chamorey E, Poudenx M, Ilie M, Gal J, Guigay J, Benzaquen J, Marquette CH, Berthet JP, Mouroux J, Schiappa R, Padovani B, Hofman P, Otto J Abstract It has been found that occurrence of immune-related adverse events...
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Related Articles Hepatitis B seroprevalence in the U.S. military and its impact on potential screening strategies. Mil Med. 2020 Jul 10;: Authors: Scott PT, Cohen RL, Brett-Major DM, Hakre S, Malia JA, Okulicz JF, Beckett CG, Blaylock JM, Forgione MA, Harrison SA, Murray CK, Rentas FJ, Fahie RL, Armstrong AW, Hayat AM, Pacha LA, Dawson P, Blackwell B, Eick-Cost AA, Maktabi HH, Michael NL, Jagodzinski LL, Cersovsky SB, Peel SA Abstract INTRODUCTION:...
Related Articles A Case Report of Hydrocephalus in a US Military Recruit. Mil Med. 2020 Jul 10;: Authors: Clerc J, Harp GM, Cathey M, Bauer M Abstract We present a case of chronic non-communicating hydrocephalus (NCH) in a US military recruit. Non-communicating hydrocephalus is a pathologic obstruction of cerebrospinal fluid (CSF) resulting in enlargement of the ventricles and elevated intracranial pressure. The patient is an 18-year-old male...
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Related Articles Conus Medullaris Teratoma: Case Report and Literature Review. Brain Tumor Res Treat. 2020 Jun 29;: Authors: Keykhosravi E, Tavallaii A, Rezaee H, Ebrahimzadeh K, Pishjoo M, Abdi R, Maftouh M, Aminzadeh B Abstract Teratomas are benign germ cell tumors that usually found out of their anatomical origin. Teratomas usually are found in sacrococcygeal area, gonads, mediastinum, cervicofacial region and intracranial fossa. Spinal teratomas...
Related Articles A Case of Intracranial Solitary Fibrous Tumor/Hemangiopericytoma Repeatedly Misdiagnosed as Hypertensive Intracerebral Hemorrhage. Brain Tumor Res Treat. 2020 Jun 29;: Authors: Eom KS, Kim HS Abstract Because solitary fibrous tumor (SFT) and hemangiopericytoma (HPC) contain identical genetic abnormalities, the World Health Organization coined the term SFT/HPC to describe these lesions. Here, we present a rare case of SFT/HPC...
Related Articles Effect of Cumulative Dexamethasone Dose during Concomitant Chemoradiation on Lymphopenia in Patients with Newly Diagnosed Glioblastoma. Brain Tumor Res Treat. 2020 Jun 29;: Authors: Lee C, Ahn S, Park JS, Song JH, Hong YK, Jeun SS Abstract BACKGROUND: Lymphopenia frequently occurs after concomitant chemoradiation (CCRT) in patients with glioblastoma (GBM) and is associated with worse overall survival (OS). A few studies have...
Related Articles Clinical Experience of Bevacizumab for Radiation Necrosis in Patients with Brain Metastasis. Brain Tumor Res Treat. 2020 Jul 09;: Authors: Park M, Gwak HS, Lee SH, Lee YJ, Kwon JW, Shin SH, Yoo H Abstract BACKGROUND: As the application of radiotherapy to brain metastasis (BM) increases, the incidence of radiation necrosis (RN) as a late toxicity of radiotherapy also increases. However, no specific treatment for RN is indicated...
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Related Articles DBDx-based drug combinations show highly potent therapeutic efficacy against human pancreatic cancer xenografts in athymic mice. Cancer Biol Ther. 2020 Aug 02;21(8):749-757 Authors: Zheng YB, Zhang MR, Li Y, Liu XJ, Zhen YS Abstract Previous studies have shown that DBDx, a combination consisting of dipyridamole, bestatin and dexamethasone is highly effective against several cancer xenografts in athymic mice. Here the therapeutic...
Related Articles A precise temperature control during hyperthermic intraperitoneal chemotherapy promises an early return of bowel function. Cancer Biol Ther. 2020 Aug 02;21(8):726-732 Authors: Ye J, Chen L, Zuo J, Peng J, Chen C, Cai S, Song W, He Y, Yuan Y Abstract INTRODUCTION: The hyperthermic intraperitoneal chemotherapy (HIPEC) has been widely applied in clinical practice for peritoneal carcinomatosis (PC). The temperature is one of the...
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Related Articles Age-Related Compensation Mechanism Revealed in the Cortical Representation of Degraded Speech. J Assoc Res Otolaryngol. 2020 Jul 08;: Authors: Anderson S, Roque L, Gaskins CR, Gordon-Salant S, Goupell MJ Abstract Older adults understand speech with comparative ease in quiet, but signal degradation can hinder speech understanding much more than it does in younger adults. This difficulty may result, in part, from temporal processing...
Related Articles New-Onset Alzheimer's Disease and Normal Subjects 100% Differentiated by P300. Am J Alzheimers Dis Other Demen. 2019 08;34(5):308-313 Authors: Jervis BW, Bigan C, Jervis MW, Besleaga M Abstract Previous work has suggested that evoked potential analysis might allow the detection of subjects with new-onset Alzheimer's disease, which would be useful clinically and personally. Here, it is described how subjects with new-onset Alzheimer's...
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Related Articles Identification of Cancer Biomarkers in Human Body Fluids by Using Enhanced Physicochemical-incorporated Evolutionary Conservation Scheme. Curr Top Med Chem. 2020 Jul 09;: Authors: Zhang J, Zhang Y, Li Y, Guo S, Yang G Abstract OBJECTIVE: Cancer is one of the most serious diseases affecting human health. Among all current cancer treatments, early diagnosis and control significantly help increase the chances of cure. Detecting...
Related Articles Naldemedine: Peripherally-acting Opioid Receptor Antagonist for Treating Opioid-induced Adverse Effects. Curr Top Med Chem. 2020 Jul 09;: Authors: Inagaki M, Kanemasa T, Yokota T Abstract Opioids are widely used for pain management in moderate-to-severe pain. However, opioids are associated with adverse events, such as constipation and emesis/vomiting. To reduce these undesired effects, a structure-activity relationship study...
Related Articles Therapeutic targets and computational approaches on drug development for COVID-19. Curr Top Med Chem. 2020 Jul 09;: Authors: Shanmugam A, Muralidharan N, Velmurugan D, Gromiha MM Abstract World Health Organization declared coronavirus disease (COVID-19) caused by SARS coronavirus-2 (SARSCoV-2) as pandemic. Its outbreak started in China in Dec 2019 and rapidly spread across all over the world. SARS-CoV-2 infected more than 800,000...
Related Articles Isothymusin, a potential inhibitor of cancer cell proliferation: An in silico and in vitro investigation. Curr Top Med Chem. 2020 Jul 09;: Authors: Singh S, Kumari P, Hussain Y, Luqman S, Meena A, Kanaojia D Abstract BACKGROUND: Since centuries plant-based compounds are known for the treatment of cancer in both traditional and contemporary medicine. The problems like target non-specificity and toxicity are well-known regarding...
Biological evaluation of selected 1,2,3-triazole derivatives as antibacterial and antibiofilm agent.
Related Articles Biological evaluation of selected 1,2,3-triazole derivatives as antibacterial and antibiofilm agent. Curr Top Med Chem. 2020 Jul 09;: Authors: André LSP, Pereira RFA, Pinheiro FR, Pascoal ACRF, Ferreira VF, de Carvalho da Silva F, Gonzaga DTG, Costa DCS, Ribeiro T, Sachs D, Aguiar-Alves F Abstract BACKGROUND: Resistance to antimicrobial agents is a major public health problem, being Staphylococcus aureus prevalent in infections...
Related Articles Vitamin C as an Anticancer Agent: Regulation of Signaling Pathways. Curr Top Med Chem. 2020 Jul 09;: Authors: Butt G, Farooqi AA, Adylova A, Attar R, Yilmaz S, Konysbayevna KK, Sabitaliyevich UY, Gasparri ML, Xu B Abstract Treatment options for effective treatment of cancer with minimum off-target effects and maximum clinical outcome have remained overarching goals in the clinical oncology. Vitamin C has remained in the shadows...
Related Articles Activation of caspase-3 by terpenoids and flavonoids in different types of cancer cells. Curr Top Med Chem. 2020 Jul 09;: Authors: Masood N, Dubey V, Luqman S Abstract BACKGROUND: Caspase-3 is accountable for the execution of apoptosis. Recently, it has gained attention as a promising target for the discovery of natural products as anticancer agents. METHODS: We have examined the efficacy of two different sets of natural...
Related Articles Current Advances and Limitations of Deep Learning in Anticancer Drug Sensitivity Prediction. Curr Top Med Chem. 2020 Jul 09;: Authors: Tan X, Yu Y, Duan K, Zhang J, Sun P, Sun H Abstract Anticancer drug screening can accelerate drug discovery to save the lives of cancer patients, but cancer heterogeneity makes it challenging. Prediction of anticancer drug sensitivity is useful for anticancer drug development and biomarker discovery....
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Related Articles Opportunities and challenges for drug discovery in modulating Adhesion G protein-coupled receptor (GPCR) functions. Expert Opin Drug Discov. 2020 Jul 10;:1-17 Authors: Bondarev AD, Attwood MM, Jonsson J, Chubarev VN, Tarasov VV, Schiöth HB Abstract INTRODUCTION: The G protein-coupled receptors (GPCR) superfamily is among the most widely exploited targets for therapeutics, with drugs mainly targeting the Rhodopsin, Glutamate...
Related Articles Automated patch clamp in drug discovery: major breakthroughs and innovation in the last decade. Expert Opin Drug Discov. 2020 Jul 10;:1-5 Authors: Obergrussberger A, Friis S, Brüggemann A, Fertig N PMID: 32646308 [PubMed - as supplied by publisher]
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