Antibiotics, Vol. 9, Pages 580: A Significant Question in Cancer Risk and Therapy: Are Antibiotics Positive or Negative Effectors? Current Answers and Possible Alternatives Antibiotics doi: 10.3390/antibiotics9090580 Authors: Steffanie S. Amadei Vicente Notario Cancer is predominantly considered as an environmental disease caused by genetic or epigenetic alterations induced by exposure to extrinsic (e.g., carcinogens, pollutants, radiation) or intrinsic (e.g., metabolic, immune or...
Sun Sep 06, 2020 03:00
Antibiotics, Vol. 9, Pages 579: Molecular Epidemiology of Carbapenem-Resistant Acinetobacter baumannii Isolated from War-Injured Patients from the Eastern Ukraine Antibiotics doi: 10.3390/antibiotics9090579 Authors: Paul G. Higgins Ralf Matthias Hagen Andreas Podbielski Hagen Frickmann Philipp Warnke Recently, a total of 32 carbapenem- and fluoroquinolone-resistant Acinetobacter baumannii (Ab) isolates was isolated from war-injured patients who were treated at German Bundeswehr...
Sat Sep 05, 2020 03:00
Antibiotics, Vol. 9, Pages 578: Recycling Old Antibiotics with Ionic Liquids Antibiotics doi: 10.3390/antibiotics9090578 Authors: Prudêncio Vieira Van der Auweraer Ferraz Antibiotics are considered one of the great “miracles” of the 20th century. Now in the 21st century in the post-antibiotic era, the miracle is turning into a nightmare, due to the growing problem of the resistance of microorganisms to classic antimicrobials and the non-investment by...
Fri Sep 04, 2020 03:00
Antibiotics, Vol. 9, Pages 576: Sonochemical Synthesis of 2’-Hydroxy-Chalcone Derivatives with Potential Anti-Oomycete Activity Antibiotics doi: 10.3390/antibiotics9090576 Authors: López Mellado Werner Said Godoy Caro Besoain Montenegro Madrid This work reports on the synthesis of eight new 2′-hydroxy-chalcones with potential anti-phytopathogenic applications in agroindustry, among others, via Claisen–Schmidt condensation and ultrasound...
Fri Sep 04, 2020 03:00
Antibiotics, Vol. 9, Pages 577: Hospital Admission Patterns in Adult Patients with Community-Acquired Pneumonia Who Received Ceftriaxone and a Macrolide by Disease Severity across United States Hospitals Antibiotics doi: 10.3390/antibiotics9090577 Authors: Thomas P. Lodise Hoa Van Le Kenneth LaPensee (1) Objective: There are limited data regarding community-acquired pneumonia (CAP) admissions patterns in US hospitals. Current expert CAP guidelines advocate for outpatient treatment...
Fri Sep 04, 2020 03:00
Antibiotics, Vol. 9, Pages 575: Clinician and Patient Factors Influencing Treatment Decisions: Ethnographic Study of Antibiotic Prescribing and Operative Procedures in Out-of-Hours and General Dental Practices Antibiotics doi: 10.3390/antibiotics9090575 Authors: Wendy Thompson Rosemary McEachan Susan Pavitt Gail Douglas Marion Bowman Jenny Boards Jonathan Sandoe Operative treatment is indicated for most toothache/dental abscesses, yet antibiotics instead of procedures...
Fri Sep 04, 2020 03:00
Antibodies, Vol. 9, Pages 45: How Do mAbs Make Use of Complement to Kill Cancer Cells? The Role of Ca2+ Antibodies doi: 10.3390/antib9030045 Authors: Taylor Lindorfer We examined the kinetics and mechanisms by which monoclonal antibodies (mAbs) utilize complement to rapidly kill targeted cancer cells. Based on results from flow cytometry, confocal microscopy and high-resolution digital imaging experiments, the general patterns which have emerged reveal cytotoxic activities mediated...
Fri Sep 04, 2020 03:00
Antioxidants, Vol. 9, Pages 833: Antioxidative Effects of Ascorbic Acid and Astaxanthin on ARPE-19 Cells in an Oxidative Stress Model Antioxidants doi: 10.3390/antiox9090833 Authors: Sanghyeon Oh Young Joo Kim Eun Kyoung Lee Sung Wook Park Hyeong Gon Yu Oxidative stress has been implicated as critical pathogenic factors contributing to the etiology of diabetic retinopathy and other retinal diseases. This study investigated antioxidative effect of ascorbic acid and astaxanthin...
Sun Sep 06, 2020 03:00
Antioxidants, Vol. 9, Pages 832: Preharvest Salicylate Treatments Enhance Antioxidant Compounds, Color and Crop Yield in Low Pigmented-Table Grape Cultivars and Preserve Quality Traits during Storage Antioxidants doi: 10.3390/antiox9090832 Authors: María E. García-Pastor Pedro J. Zapata Salvador Castillo Domingo Martínez-Romero Daniel Valero María Serrano Fabián Guillén Previous reports reported on the effectiveness of preharvest salicylic acid (SA) treatment on increasing...
Sun Sep 06, 2020 03:00
Antioxidants, Vol. 9, Pages 831: Beneficial Regulatory Effects of Polymethoxyflavone—Rich Fraction from Ougan (Citrus reticulata cv. Suavissima) Fruit on Gut Microbiota and Identification of Its Intestinal Metabolites in Mice Antioxidants doi: 10.3390/antiox9090831 Authors: Jiebiao Chen Yue Wang Tailin Zhu Sijia Yang Jinping Cao Xian Li Li-Shu Wang Chongde Sun Polymethoxyflavones (PMFs) are special flavonoids in citrus fruits that have been suggested to be beneficial...
Sun Sep 06, 2020 03:00
Antioxidants, Vol. 9, Pages 830: Oxidative Stress and Neuroinflammation as a Pivot in Drug Abuse. A Focus on the Therapeutic Potential of Antioxidant and Anti-Inflammatory Agents and Biomolecules Antioxidants doi: 10.3390/antiox9090830 Authors: Pablo Berríos-Cárcamo Mauricio Quezada María Elena Quintanilla Paola Morales Marcelo Ezquer Mario Herrera-Marschitz Yedy Israel Fernando Ezquer Drug abuse is a major global health and economic problem. However, there are no...
Fri Sep 04, 2020 03:00
Antioxidants, Vol. 9, Pages 829: Targeting Heme Oxygenase-1 in the Arterial Response to Injury and Disease Antioxidants doi: 10.3390/antiox9090829 Authors: William Durante Heme oxygenase-1 (HO-1) catalyzes the degradation of heme into carbon monoxide (CO), iron, and biliverdin, which is rapidly metabolized to bilirubin. The activation of vascular smooth muscle cells (SMCs) plays a critical role in mediating the aberrant arterial response to injury and a number of vascular diseases. Pharmacological...
Fri Sep 04, 2020 03:00
Antioxidants, Vol. 9, Pages 828: A Higher Proportion of Eicosapentaenoic Acid (EPA) When Combined with Docosahexaenoic Acid (DHA) in Omega-3 Dietary Supplements Provides Higher Antioxidant Effects in Human Retinal Cells Antioxidants doi: 10.3390/antiox9090828 Authors: Manuel Saenz de Viteri María Hernandez Valentina Bilbao-Malavé Patricia Fernandez-Robredo Jorge González-Zamora Laura Garcia-Garcia Nahia Ispizua Sergio Recalde Alfredo Garcia-Layana Retinal pigment...
Fri Sep 04, 2020 03:00
Antioxidants, Vol. 9, Pages 827: Pharmacokinetics of Repeated Oral Dosing with Coenzyme Q10 in Cavalier King Charles Spaniels with Myxomatous Mitral Valve Disease Antioxidants doi: 10.3390/antiox9090827 Authors: Liselotte B. Christiansen Malene K. Morsing Maria Josefine Reimann Torben Martinussen Zita Birlie Anne Marie V. Schou-Pedersen Jens Lykkesfeldt Lisbeth H. Olsen Coenzyme Q10 (Q10) is a mitochondrial cofactor and an antioxidant with the potential to combat...
Fri Sep 04, 2020 03:00
Arts, Vol. 9, Pages 95: Crossing Cultural Boundaries: Saint George in the Eastern Mediterranean under the Latinokratia (13th–14th Centuries) and His Mythification in the Crown of Aragon Arts doi: 10.3390/arts9030095 Authors: Castiñeiras The cult of St George in the Eastern Mediterranean is one of the most extraordinary examples of cohabitation among different religious communities. For a long time, Greek Orthodox, Latins, and Muslims shared shrines dedicated to the Cappadocian warrior...
Fri Sep 04, 2020 03:00
Arts, Vol. 9, Pages 94: From Patricide to Patrilineality: Adapting The Wandering Earth for the Big Screen Arts doi: 10.3390/arts9030094 Authors: Ping Zhu This paper discusses how Liu Cixin’s 2000 novella “The Wandering Earth” was adapted into a family melodrama that ultimately reinforces the authority of the Father and the nation-state. It analyzes the complex mechanisms, such as mise en abyme and scapegoating, that serve to condone the patriarch’s...
Fri Sep 04, 2020 03:00
Atmosphere, Vol. 11, Pages 952: Detection of Extreme Phenomena in the Stable Boundary Layer over the Amazonian Forest Atmosphere doi: 10.3390/atmos11090952 Authors: Francisco O. Miranda Fernando M. Ramos Celso von Randow Cléo Q. Dias-Júnior Marcelo Chamecki Jose D. Fuentes Antônio O. Manzi Marceliano E. de Oliveira Cledenilson M. de Souza We apply different methods for detection of extreme phenomena (EP) in air-turbulent time series measured in the nocturnal boundary...
Sun Sep 06, 2020 03:00
Atmosphere, Vol. 11, Pages 951: Behaviors of Chromium in Coal-Fired Power Plants and Associated Atmospheric Emissions in Guizhou, Southwest China Atmosphere doi: 10.3390/atmos11090951 Authors: Zhonggen Li Qingfeng Wang Zhongjiu Xiao Leilei Fan Dan Wang Xinyu Li Jia Du Junwei Cheng Coal burning is a main concern for a range of atmospheric pollutants, including the environmentally sensitive element chromium (Cr). Cr migrates to the environment through stack emissions...
Sun Sep 06, 2020 03:00
Atmosphere, Vol. 11, Pages 950: Modulation of ENSO Teleconnection on the Relationship between Arctic Oscillation and Wintertime Temperature Variation in South Korea Atmosphere doi: 10.3390/atmos11090950 Authors: Sung-Ho Woo Jahyun Choi Jee-Hoon Jeong Despite progressing global warming, extreme cold events in East Asia are still occurring frequently with temperature variability enhanced. To understand this situation, it is necessary to determine external and internal climatic factors...
Sun Sep 06, 2020 03:00
Atmosphere, Vol. 11, Pages 949: Measurements of Cloud Radiative Effect across the Southern Ocean (43° S–79° S, 63° E–158° E) Atmosphere doi: 10.3390/atmos11090949 Authors: Haoran Wang Andrew R. Klekociuk W. John R. French Simon P. Alexander Tom A. Warner The surface radiation environment over the Southern Ocean within the region bound by 42.8° S to 78.7° S and 62.6° E to 157.7° W is summarised for three austral summers. This is done using ship-based...
Sat Sep 05, 2020 03:00
Atmosphere, Vol. 11, Pages 948: Comparison of GC-μECD and OA-ICOS Methods for High-Precision Measurements of Atmospheric Nitrous Oxide (N2O) at a Korean GAW Station Atmosphere doi: 10.3390/atmos11090948 Authors: Haeyoung Lee Miyoung Ko Sumin Kim Wonick Seo Young-San Park Nitrous oxide (N2O) is a powerful greenhouse gas and is the largest remaining anthropogenic source of stratospheric ozone-depleting substances as halocarbons return towards preindustrial levels. To verify...
Sat Sep 05, 2020 03:00
Atmosphere, Vol. 11, Pages 947: Climate and the Global Spread and Impact of Bananas’ Black Leaf Sigatoka Disease Atmosphere doi: 10.3390/atmos11090947 Authors: Eric Strobl Preeya Mohan While Black Sigatoka Leaf Disease (Mycosphaerella fijiensis) has arguably been the most important pathogen affecting the banana industry over the past 50 years, there are no quantitative estimates of what risk factors determine its spread across the globe, nor how its spread has affected banana producing...
Sat Sep 05, 2020 03:00
Atmosphere, Vol. 11, Pages 946: Initiation and Organization Mechanisms of Mesoscale Convective Systems in a Warm-Sector Torrential Rainfall Event over Beijing Atmosphere doi: 10.3390/atmos11090946 Authors: Lei Yin Jiahua Mao Fan Ping Xiaofan Li Ning Wang A torrential rainfall that occurred in Beijing during the period of 21–22 July 2012 is simulated by the Weather Research and Forecasting Model in order to investigate the probable mechanisms for the initiation and...
Fri Sep 04, 2020 03:00
Atmosphere, Vol. 11, Pages 945: Numerical Simulation Analysis of the Impact of Urbanization on an Extreme Precipitation Event over Beijing–Tianjin–Hebei, China Atmosphere doi: 10.3390/atmos11090945 Authors: Jing Zhang Yu-shu Zhou Xin-yong Shen In this study, an extreme rainstorm that occurred in the Beijing–Tianjin–Hebei (BTH) region in China on 19–20 July 2016 is simulated and analyzed using the Weather Research and Forecasting model, coupled with...
Fri Sep 04, 2020 03:00
Atmosphere, Vol. 11, Pages 944: The Observation and Characterisation of Fluorescent Bioaerosols Using Real-Time UV-LIF Spectrometry in Hong Kong from June to November 2018 Atmosphere doi: 10.3390/atmos11090944 Authors: Douglas Morrison Jinjian Li Ian Crawford Wenwei Che Michael Flynn Man Nin Chan Alexis K. H. Lau Jimmy C. H. Fung David Topping Jianzhen Yu Martin Gallagher Hong Kong is an area of complex topography, with mixtures of urban and greenbelt spaces....
Fri Sep 04, 2020 03:00
Bioengineering, Vol. 7, Pages 105: Electrospun Scaffolds and Induced Pluripotent Stem Cell-Derived Cardiomyocytes for Cardiac Tissue Engineering Applications Bioengineering doi: 10.3390/bioengineering7030105 Authors: Taylor Cook Suh Alaowei Y. Amanah Jessica M. Gluck Tissue engineering (TE) combines cells, scaffolds, and growth factors to assemble functional tissues for repair or replacement of tissues and organs. Cardiac TE is focused on developing cardiac cells, tissues, and...
Sun Sep 06, 2020 03:00
Biology, Vol. 9, Pages 273: Characterization of Perionyx excavatus Development and Its Head Regeneration Biology doi: 10.3390/biology9090273 Authors: Yun Seon Bae Jung Kim Jeesoo Yi Soon Cheol Park Hae-Youn Lee Sung-Jin Cho Regeneration is a biological process restoring lost or amputated body parts. The capability of regeneration varies among organisms and the regeneration of the central nervous system (CNS) is limited to specific animals, including the earthworm Perionyx...
Sat Sep 05, 2020 03:00
Biology, Vol. 9, Pages 274: Hummingbird-Leaves-Reared Black Soldier Fly Prepupae: Assessment of Nutritional and Heavy Metal Compositions Biology doi: 10.3390/biology9090274 Authors: Giva Kuppusamy Chee Kei Kong Ganeswaran Chandra Segaran Eliyarajan Tarmalingam Max Herriman Mohd Fathil Ismail Tahir Mehmood Khan Liang Ee Low Bey-Hing Goh Black soldier fly (BSF) larva is an attractive animal feed replacer due to its noticeable nutritional content. However, the conventional...
Sat Sep 05, 2020 03:00
Biology, Vol. 9, Pages 275: General Microbiota of the Soft Tick Ornithodoros turicata Parasitizing the Bolson Tortoise (Gopherus flavomarginatus) in the Mapimi Biosphere Reserve, Mexico Biology doi: 10.3390/biology9090275 Authors: Sergio I. Barraza-Guerrero César A. Meza-Herrera Cristina García-De la Peña Vicente H. González-Álvarez Felipe Vaca-Paniagua Clara E. Díaz-Velásquez Francisco Sánchez-Tortosa Verónica Ávila-Rodríguez Luis M. Valenzuela-Núñez Juan C. Herrera-Salazar...
Sat Sep 05, 2020 03:00
Biology, Vol. 9, Pages 271: National Publication Productivity during the COVID-19 Pandemic—A Preliminary Exploratory Analysis of the 30 Countries Most Affected Biology doi: 10.3390/biology9090271 Authors: Simon M. Müller Georg F. Mueller Alexander A. Navarini Oliver Brandt Background: The COVID 19 pandemic increased publication productivity enormously with numerous new COVID-19-related articles appearing daily, despite the fact that many health care workers in the partially...
Sat Sep 05, 2020 03:00
Biology, Vol. 9, Pages 272: A Deep Learning-Based System (Microscan) for the Identification of Pollen Development Stages and Its Application to Obtaining Doubled Haploid Lines in Eggplant Biology doi: 10.3390/biology9090272 Authors: Edgar García-Fortea Ana García-Pérez Esther Gimeno-Páez Alfredo Sánchez-Gimeno Santiago Vilanova Jaime Prohens David Pastor-Calle The development of double haploids (DHs) is a straightforward path for obtaining pure lines but has multiple...
Sat Sep 05, 2020 03:00
Biology, Vol. 9, Pages 268: A Lipidomic Analysis of Leaves of Esca-Affected Grapevine Suggests a Role for Galactolipids in the Defense Response and Appearance of Foliar Symptoms Biology doi: 10.3390/biology9090268 Authors: Piebiep Goufo Isabel Cortez Both qualitative and quantitative changes occur in the lipid composition of Vitis vinifera L. tissues, which may compromise the defense response against Esca complex disease, a widespread and damaging trunk disease. In this study, a lipidomic...
Fri Sep 04, 2020 03:00
Biology, Vol. 9, Pages 270: Managing Rhizoctonia Damping-Off of Rocket (Eruca sativa) Seedlings by Drench Application of Bioactive Potato Leaf Phytochemical Extracts Biology doi: 10.3390/biology9090270 Authors: Catello Pane Michele Caputo Gianluca Francese Gelsomina Manganiello Roberto Lo Lo Scalzo Giuseppe Mennella Massimo Zaccardelli Plants produce a huge array of secondary metabolites that play a key role in defense mechanisms against detrimental microorganisms and...
Fri Sep 04, 2020 03:00
Biology, Vol. 9, Pages 269: Oxidative Stress in Reproduction: A Mitochondrial Perspective Biology doi: 10.3390/biology9090269 Authors: Alexandra Almansa-Ordonez Raquel Bellido Rita Vassena Montserrat Barragan Filippo Zambelli Mitochondria are fundamental organelles in eukaryotic cells that provide ATP through oxidative phosphorylation. During this process, reactive oxygen species (ROS) are produced, and an imbalance in their concentrations can induce oxidative stress (OS),...
Fri Sep 04, 2020 03:00
Biology, Vol. 9, Pages 267: Computational Modeling of Skull Bone Structures and Simulation of Skull Fractures Using the YEAHM Head Model Biology doi: 10.3390/biology9090267 Authors: Alcino Barbosa Fábio A. O. Fernandes Ricardo J. Alves de Sousa Mariusz Ptak Johannes Wilhelm The human head is a complex multi-layered structure of hard and soft tissues, governed by complex materials laws and interactions. Computational models of the human head have been developed over the years,...
Fri Sep 04, 2020 03:00
Biomedicines, Vol. 8, Pages 333: Withanolide Metabolites Inhibit PI3K/AKT and MAPK Pro-Survival Pathways and Induce Apoptosis in Acute Myeloid Leukemia Cells Biomedicines doi: 10.3390/biomedicines8090333 Authors: Nosheen Akhtar Muhammad Waleed Baig Ihsan-ul Haq Vinothini Rajeeve Pedro Rodriguez Cutillas Acute myeloid leukemia (AML) is an aggressive disease and, despite advances, its treatment remains challenging. Therefore, it remains important to identify new agents for...
Sun Sep 06, 2020 03:00
Biomedicines, Vol. 8, Pages 332: Targeting Alternative Splicing as a Potential Therapy for Episodic Ataxia Type 2 Biomedicines doi: 10.3390/biomedicines8090332 Authors: Fanny Jaudon Simona Baldassari Ilaria Musante Agnes Thalhammer Federico Zara Lorenzo A. Cingolani Episodic ataxia type 2 (EA2) is an autosomal dominant neurological disorder characterized by paroxysmal attacks of ataxia, vertigo, and nausea that usually last hours to days. It is caused by loss-of-function...
Sat Sep 05, 2020 03:00
Biomedicines, Vol. 8, Pages 331: Psilocybin as a New Approach to Treat Depression and Anxiety in the Context of Life-Threatening Diseases—A Systematic Review and Meta-Analysis of Clinical Trials Biomedicines doi: 10.3390/biomedicines8090331 Authors: Ana Sofia Vargas Ângelo Luís Mário Barroso Eugenia Gallardo Luísa Pereira Psilocybin is a naturally occurring tryptamine known for its psychedelic properties. Recent research indicates that psilocybin may constitute a valid approach...
Sat Sep 05, 2020 03:00
Biomedicines, Vol. 8, Pages 330: BAY 41-2272 Attenuates CTGF Expression via sGC/cGMP-Independent Pathway in TGFβ1-Activated Hepatic Stellate Cells Biomedicines doi: 10.3390/biomedicines8090330 Authors: Po-Jen Chen Liang-Mou Kuo Yi-Hsiu Wu Yu-Chia Chang Kuei-Hung Lai Tsong-Long Hwang Activation of hepatic stellate cells (HSCs) is a critical pathogenic feature of liver fibrosis and cirrhosis. BAY 41-2272 is a canonical non-nitric oxide (NO)-based soluble guanylyl cyclase...
Fri Sep 04, 2020 03:00
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