Acquired hemophilia A (AHA) is an extremely rare and serious bleeding disorder caused by autoantibodies against coagulation factor VIII (FVIII). Approximately, 10% of patients with AHA have an underlying malignancy. We report on a 46-year-old man with AHA and advanced oral cancer who presented with massive bleeding after surgery. Preoperative blood coagulation tests showed no abnormalities. He underwent radical tumor resection followed by reconstruction using a free rectus abdominal musculocutaneous...
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Abstract Background Both inflammatory bowel disease (IBD) and chronic rhinosinusitis (CRS) are characterized by dysregulated immune responses. Though previous studies have demonstrated the coexistence of IBD and CRS, investigations of their association using large sets of epidemiologic data are lacking. Methods We examined IBD and the subsequent risk of CRS in a nationwide setting. For January 1, 2000 to December 31, 2010, we identified in the National Health Insurance Dataset of Taiwan...
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Condition: Carcinoma, NasopharyngealInterventions: Radiation: Accelerated Radiotherapy; Radiation: Non Accelerated RadiotherapySponsors: Postgraduate Institute of Medical Education and Research; Indian Council of Medical ResearchRecruiting
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Abstract Purpose To improve the efficacy of music therapy on tinnitus relief, specific music that was not repetitively played and satisfies individualized preference was developed. The aim of this study was to investigate effects of combination of the specific music and educational counseling on tinnitus relief in short term. Methods Sixty patients suffering...
Abstract Purpose We aimed to demonstrate whether chronic otitis media with effusion (OME) is a sterile condition or biofilms-related disease through direct visualization of middle ear mucosa by Scanning electron microscopy (SEM) and culture of the effusion. Methods This case–control study included 60 children in two groups; the case group included 50 patients...
Abstract Objective Identify the critical points that lead to recurrences and lack of radicality in endolymphatic sac tumors (ELSTs). Study design Retrospective case study and review of the literature. Setting Tertiary referral center. ...
Abstract Purpose Bilateral cochlear implant (CI) implantation is increasingly used in the auditory rehabilitation of bilaterally deafened adults. However, after successful unilateral implantation, objective patient counselling is essential. Methods We investigated the extra benefit of a second CI in adults in terms of health-related quality of life, tinnitus,...
In the original publication of the article, the third author name was published incorrectly. The correct name is Edwin Yuen Hao Tong.
Abstract Purpose Emergent tracheostomy under local anaesthesia is a reliable method of airway management when orotracheal intubation is not possible. COVID-19 is spread through aerosol making the emergent tracheostomy a high-risk procedure for surgeons. The surgical establishment of the air conduit in emergency scenarios must be adjusted for safety reasons. Methods ...
Abstract Background The neutrophil-to-lymphocyte ratio (NLR) has been shown to be associated with the progression of laryngeal cancer (LC), but studies have reported inconsistent results. We systematically evaluated the effect of the pretreatment NLR on the prognosis of LC in the meta-analysis. Method The PubMed, Embase, Web of Science, and Cochrane Library...
Abstract Purpose To evaluate validity and reliability of Lithuanian version of Nasal Obstruction Symptom Evaluation Scale (L-NOSE), designed for the assessment of nasal obstruction. Methods Cross-cultural adaptation of L-NOSE was accomplished according to generally accepted methodology. L- NOSE was tested for its reliability, validity, and responsiveness...
Abstract Purpose The present study aimed to provide the clinicopathological data of Brazilian patients with basal cell adenoma (BCA). Methods Records of BCA cases were retrospectively gathered from the Brazilian National Cancer Institute database between 1996 and 2006. All cases were histopathologically reviewed, and the clinicopathological data were collected...
Abstract Purpose The self-crosslinked hyaluronic acid (scHA) and steroids are considered as efficient factors for postoperative management after chronic rhinosinusitis (CRS) nasal surgery. This randomized clinical trial is designed to investigate the efficacy and potential of scHA gel as a topical drug sustained release carrier for steroid of budesonide. Methods ...
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Abstract Epidermolysis bullosa simplex (EBS) is a rare skin disease usually inherited in an autosomal dominant pattern. EBS is resulting from mutations in keratin 5 (KRT5) and keratin 14 (KRT14) genes encoding the keratins 5 and 14 proteins expressed in the keratinocytes of the basal layer of the epidermis. To date, seven pathogenic mutations have been reported to be responsible for EBS in the Canadian population from the province of Quebec: p.Pro25Leu, p.Leu150Pro, p.Met327Thr, and p.Arg559X in...
Abstract Background Atopic dermatitis (AD) is driven by the interplay between a dysfunctional epidermal barrier and a skewed cutaneous immune dysregulation. As part of the complex skin barrier dysfunction abnormalities in lipid organization and microbiome composition have been described. We set out to systematically investigate the composition of the stratum corneum lipidome, skin microbiome, and skin physiology parameters at three different body sites in patients with AD and healthy volunteers....
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Bond failure during fixed orthodontic treatment is a frequently occurring problem. As bracket rebonding is associated with reduced shear bond strength, the aim of the present investigation is to analyse the ef...
The objectives of this study were to study the prevalence of temporomandibular joint disorder (TMD) and its association with anxiety, depression, and stress among the general Lebanese population as well as in ...
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Abstract Background Recurrent immunotherapy‐induced audiovestibular toxicity despite cessation of therapy has not been reported. Methods We report the first case of recurrent audiovestibular toxicity following immune‐checkpoint inhibitor (ICI) therapy. The patient was seen with sudden bilateral hearing loss and disequilibrium. After ruling out other etiologies, he was diagnosed with audiovestibular and neurological immune‐related adverse events (irAEs). He received systemic steroids, with...
Abstract Background Programmed death‐1 checkpoint inhibitors, such as nivolumab, have successfully been utilized for recurrent or metastatic squamous cell carcinoma of the head and neck; however, their use may be associated with immune‐related adverse effects (irAEs). Methods We describe a case of tracheobronchial chondritis as a rare irAE in a 72‐year‐old man with multiple pulmonary metastases of hypopharyngeal squamous cell carcinoma treated with nivolumab, who was seen with a 2‐week...
Abstract Background This study aims to evaluate the cost‐effectiveness of using heat and moisture exchangers (HMEs) vs alternative stoma covers (ASCs) following laryngectomy in the United States. Methods A cost‐effectiveness and budget impact analysis were conducted including uncertainty analyses using real‐world survey data with pulmonary events and productivity loss. Results HME use was more effective and less costly compared with ASCs. Quality‐adjusted life years were slightly...
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Abstract Deep fungal infections rarely involve the oral cavity and most commonly affect immunocompromised patients. Oral deep fungal infections typically manifest as chronic mucosal ulcerations or granular soft tissue overgrowths. Since these lesions are non-specific and can mimic malignancy, it is crucial to obtain a thorough clinical history and an adequate biopsy to render the appropriate diagnosis. We report four new cases of deep fungal infections, diagnosed as histoplasmosis,...
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Zusammenfassung Einführung Die Hörrehabilitation mittels Cochleaimplantat (CI) ist auch für Patienten mit cochleovestibulären Schwannomen von zunehmendem Interesse. Berichtet wird über Erfahrungen bezüglich des chirurgischen Managements von Tumoren mit einer seltenen transmodiolären oder transmakulären Ausdehnung und über die Ergebnisse bei Hörrehabilitation mit CI. Methode ...
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Related Articles The endolymphatic sac tumor: challenges in the eradication of a localized disease. Eur Arch Otorhinolaryngol. 2020 Sep 05;: Authors: Sykopetrites V, Piras G, Giannuzzi A, Caruso A, Taibah A, Sanna M Abstract OBJECTIVE: Identify the critical points that lead to recurrences and lack of radicality in endolymphatic sac tumors (ELSTs). STUDY DESIGN: Retrospective case study and review of the literature. SETTING:...
Related Articles Otitis media with effusion is not a sterile inflammatory process: scanning electron microscope evidence. Eur Arch Otorhinolaryngol. 2020 Sep 05;: Authors: Elzayat S, Nosair N, Ghazy AA, Abdulghaffar IA Abstract PURPOSE: We aimed to demonstrate whether chronic otitis media with effusion (OME) is a sterile condition or biofilms-related disease through direct visualization of middle ear mucosa by Scanning electron microscopy (SEM)...
Related Articles Single-centre experience and practical considerations of the benefit of a second cochlear implant in bilaterally deaf adults. Eur Arch Otorhinolaryngol. 2020 Sep 05;: Authors: Péus D, Pfluger A, Häussler SM, Knopke S, Ketterer MC, Szczepek AJ, Gräbel S, Olze H Abstract PURPOSE: Bilateral cochlear implant (CI) implantation is increasingly used in the auditory rehabilitation of bilaterally deafened adults. However, after successful...
Related Articles Correction to: Use of PerClot® in head and neck surgery: a Scottish centre experience. Eur Arch Otorhinolaryngol. 2020 Sep 05;: Authors: Rao K, Gomati A, Tong EYH, W Ah-See K, Shakeel M Abstract In the original publication of the article, the third author name was published incorrectly. The correct name is Edwin Yuen Hao Tong. PMID: 32889622 [PubMed - as supplied by publisher]
Related Articles Emergent tracheostomy during the pandemic of COVID-19: Slovenian National Recommendations. Eur Arch Otorhinolaryngol. 2020 Sep 05;: Authors: Šifrer R, Urbančič J, Piazza C, van Weert S, García-Purriños F, Benedik J, Tancer I, Aničin A Abstract PURPOSE: Emergent tracheostomy under local anaesthesia is a reliable method of airway management when orotracheal intubation is not possible. COVID-19 is spread through aerosol making...
Related Articles Prognostic significance of pretreatment neutrophil-to-lymphocyte ratio in patients with laryngeal cancer: a systematic review and meta-analysis. Eur Arch Otorhinolaryngol. 2020 Sep 04;: Authors: Yang F, Huang Q, Guan Z, Diao Q Abstract BACKGROUND: The neutrophil-to-lymphocyte ratio (NLR) has been shown to be associated with the progression of laryngeal cancer (LC), but studies have reported inconsistent results. We systematically...
Related Articles Cross-cultural adaptation and validation of Lithuanian-NOSE scale. Eur Arch Otorhinolaryngol. 2020 Sep 04;: Authors: Balsevicius T, Padervinskis E, Pribuisiene R, Kuzminiene A, Vaitkus S, Liutkevicius V Abstract PURPOSE: To evaluate validity and reliability of Lithuanian version of Nasal Obstruction Symptom Evaluation Scale (L-NOSE), designed for the assessment of nasal obstruction. METHODS: Cross-cultural adaptation...
Related Articles A retrospective study of 30 basal cell adenomas of the salivary gland in a Brazilian population and literature review. Eur Arch Otorhinolaryngol. 2020 Sep 04;: Authors: Cordeiro MS, de Freitas Filho SAJ, Servato JPS, Eisenberg ALA, Dias FL, de Faria PR, Loyola AM, Cardoso SV Abstract PURPOSE: The present study aimed to provide the clinicopathological data of Brazilian patients with basal cell adenoma (BCA). METHODS:...
Related Articles The postoperative outcomes of patients with chronic rhinosinusitis with nasal polyps by sustained released steroid from hyaluronic acid gel. Eur Arch Otorhinolaryngol. 2020 Sep 04;: Authors: Zhang H, Hu L, Li W, Lai Y, Zhou J, Wang D Abstract PURPOSE: The self-crosslinked hyaluronic acid (scHA) and steroids are considered as efficient factors for postoperative management after chronic rhinosinusitis (CRS) nasal surgery. This...
Related Articles The imaging anatomy of ethmomaxillary sinus and its impact on chronic rhinosinusitis. Eur Arch Otorhinolaryngol. 2020 Sep 02;: Authors: Zhou F, Cao C, Fan W, Tan L, Liu P, Lv H, Xu Y Abstract PURPOSE: The aim of this study was to investigate the pneumatization degree of ethmomaxillary sinus (EMS) and adjacent structures, and its impact on chronic rhinosinusitis (CRS). METHODS: A retrospective analysis of paranasal...
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J Neurol Surg B Skull BaseDOI: 10.1055/s-0040-1715470 Objective The carotico-clinoid foramen and interclinoid bridge are two anatomical variants of the sellar region. If these anatomical variants go unrecognized and are not managed safely by the surgeon during expanded endoscopic endonasal surgery for a posterior clinoidectomy, a carotid artery injury may occur. We summarize a method to safely navigate in the presence of the carotico-clinoid foramen and interclinoid bridge in an endoscopic...
J Neurol Surg B Skull BaseDOI: 10.1055/s-0040-1705160Expanded endonasal endoscopic approaches provide access to the entire central skull base and craiocervical junction. The authors present a case of an 81-year-old man who presented with progressive spastic quadriparesis to the point of being wheel-chair bound. Cervical spine computed tomography (CT) and magnetic resonance imaging (MRI) demonstrated multilevel extensive spondylitic changes with a large pannus at the C1–2 junction, severely compressing...
J Neurol Surg B Skull BaseDOI: 10.1055/s-0040-1713938Orbital pathology requiring surgery can be planned based on the nature of the disease and the position of this relative to the globe and optic nerve complex. Multidisciplinary treatment is now common, and this sometimes includes multiple surgical corridors employed for approach. The orbit is also now frequently used as a corridor to intracranial pathology, and these same processes may be applied. Combined surgical approaches, whether at the same...
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Abstract Primary thyroid lymphoma is a rare malignancy, accounting for 1–2% of extra-nodal lymphomas and 1–5% of thyroid malignancies. Diffuse large B-cell lymphoma is the most common type of primary thyroid lymphoma. It usually presents with a rapidly enlarging neck mass with cervical lymphadenopathy. Though rare, early diagnosis of this condition is important because its management is quite different from the treatment of other thyroid neoplasms. It is usually treated by chemotherapy...
Abstract Cribriform plate is the commonest site of Cerebrospinal fluid (CSF) leak, its fragility and juxtaposition of arachnoid’s investment to the bone, where the olfactory nerve pierces the skull, is a vulnerable site for CSF leak. Endoscopic transnasal approach has been the main stay for CSF leak repair over the past 2 decades. The technique and surgical steps of Endoscopic Surgical Repair of Cribriform CSF Leak using Free Septal Mucosal Graft without Postoperative Nasal packs...
Abstract Temporal processing is critical to a wide variety of everyday listening tasks, including speech perception. Although the importance of signal to noise ratio (SNR) is well documented in speech perception experiments, it is less explored in temporal processing experiments. The present study examined the effect of SNR on temporal processing abilities using Gap Detection Threshold (GDT) in children and adults. The study included a total of 45 subjects, where in, 25 children...
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Objective: To investigate the effects of habitual sniffing on the postoperative course of pars flaccida cholesteatoma. Study Design: Retrospective case series study. Setting: University hospital. Patients: Forty-nine patients (53 ears) with pars flaccida cholesteatoma and history of habitual sniffing before the initial operation. Interventions: Patients were divided into a “sniffing cessation group” characterized by sniffing cessation and a “continual sniffing...
Objective: To assess the accessibility and breadth of online information regarding neurotology fellowship programs by appraising individual fellowship websites as well as two popular online databases. Methods: The American Neurotology Society Program Information Page (ANSPIP), the American Medical Association's Fellowship and Residency Electronic Interactive Database (FREIDA), and three online search engines (Google, Yahoo, Bing) were assessed for accessibility to individual fellowship...
Objectives/Hypothesis: Quinine, a cinchona bark-derived antimalarial alkaloid, is a known ototoxic. Isolated and named in 1820 by the French scientists Pierre-Joseph Pelletier and Joseph-Bienaimé Caventou, it has since been employed in the treatment of different maladies. Quinine was also recommended as a local anesthetic in surgical procedures in the early 20th century. This article aims to identify early ototoxicity reports regarding quinine and to investigate if quinine was previously used...
Objective: To describe the outcome and feasibility of an exclusive endoscopic transcanal transpromontorial approach (ETTA) for decompression of the labyrinthine segment of the facial nerve (LSFN). Patient: A 60-year-old man with a left-sided transverse fracture of temporal bone involving the LSFN, resulting in a grade VI House–Brackmann (HB) facial palsy, associated with ipsilateral total sensorineural hearing loss. Intervention: Surgical decompression of the LSFN by ETTA....
Video Summary:http://links.lww.com/MAO/B51 Address correspondence and reprint requests to Alejandro Rivas, M.D., Department of Otolaryngology—Head and Neck Surgery, The Bill Wilkerson Center for Otolaryngology and Communication Sciences, 7209 Medical Center East South Tower, 1215 21st Avenue South, Nashville, TN 37232-8605; E-mail: alejandro.rivas@vumc.org No funding or other support was provided for this study. A.R.: Consultant for Med-El, Advanced Bionics, Cochlear, Grace Medical, Stryker,...
Objective: PubMed is the world's largest online collection of biomedical literature citations. A PubMed search (October 11, 2019) using the medical subject heading terms “history” and “mastoidectomy” was conducted. The heading “best matches” listed as first article “A brief history of mastoidectomy,” a very relevant free full text. The aim of this study is to validate or not the relevance attributed to this study as the first article listed in best matches. Methodology: All the references...
Objective: To describe a case of bilateral sudden sensorineural hearing loss (SSNHL) and intralabyrinthine hemorrhage in a patient with COVID-19. Study Design: Clinical capsule report. Setting: Tertiary academic referral center. Patient: An adult woman with bilateral SSNHL, aural fullness, and vertigo with documented SARS-CoV-2 infection (IgG serology testing). Interventions: High-dose oral prednisone with taper, intratympanic dexamethasone. Main Outcome...
SDC Video Link:http://links.lww.com/MAO/B86. Address correspondence and reprint requests to Estefanía Zanotti, M.D., 951 La Rioja St, Ciudad Autónoma de Buenos Aires, Buenos Aires, Argentina C1221; E-mail: estefania.zanotti@gmail.com The authors disclose no conflicts of interest. Supplemental digital content is available for this article. Direct URL citations appear in the printed text and are provided in the HTML and PDF versions of this article on the journal's Website (http://journals.lww.com/otology-neurotology)....
Objective: To evaluate the auditory and speech benefit of bimodal stimulation for prelingual deafened cochlear implantation recipients. Study Design: Retrospective and comparative study. Setting: Tertiary referral center. Patients: Fifty-six children with bilateral prelingual profound sensorineural hearing loss were enrolled, including 28 consecutive children with unilateral cochlear implantation (CI group), and 28 consecutive children with bimodal stimulation (BI...
Objective: Infectious complications occurring in cochlear implant (CI) recipients is of potentially major impact. A better understanding of severe infections in this cohort is necessary. Design: Single-center, retrospective cohort study. Level of Evidence 2B. Setting: Single-center, retrospective cohort study at a tertiary referral hospital. Participants and interventions: We included all patients who received a CI at our institution between 1983 and end of 2018 (4,622...
Objective: To assess the usefulness of numeric grading scales of middle ear risk in predicting ossiculoplasty hearing outcomes. Study Design: Retrospective review. Setting: Tertiary care, academic medical center. Patients: Adults and children undergoing ossiculoplasty between May 2013 and May 2019 including: synthetic ossicular replacement prosthesis, autograft interposition, bone cement repair, and mobilization of lateral chain fixation. Intervention: Cases...
Objective: Cochlear implantation in children with inner ear malformations has been shown to be beneficial. The aims of this study are to evaluate open set word recognition outcomes among children with cochlear implants who have cochlear malformations, and to further assess if either the lateral wall (LW) or perimodiolar (PM) electrode arrays confer any performance outcome advantages. Study Design: Retrospective case series. Setting: Tertiary referral center. Patients: ...
Objective: Understand the frailty of vestibular schwannoma surgical patients and how frailty impacts clinical course. Study Design: Retrospective Cohort. Setting: Single-tertiary academic hospital. Patients: All patients undergoing vestibular schwannoma surgery. Intervention: The modified frailty index (mFI) was calculated for all patients undergoing surgery for vestibular schwannoma between 2011 and 2018. Patient demographics and medical history, perioperative...
Objective: To evaluate in cochlear implant patients, the feasibility and reliability of angular depth of insertion (aDOI) measurements using plain x-ray scans. Study Design: Retrospective study where three observers independently evaluated and compared intraoperative anterior-posterior and oblique x-ray scans. Setting: A tertiary pediatric medical center. Patients: Included were 50 children (100 ears) who underwent bilateral simultaneous cochlear implantation during...
Introduction: Tympanic membrane retraction (TMR) is a relatively common otologic finding. Currently, there is no consensus on the optimal treatment of TMR. Some ENT-surgeons advocate surgical correction while others opt for a watchful-waiting policy. Our aim was to investigate the natural course of retraction pockets in the posterosuperior quadrant of the pars tensa in a large cohort of patients. Methods: An observational retrospective cohort study was conducted including patients of...
Hypothesis: Epithelial ion transport pathologies of the endolymphatic sac (ES) are associated with large vestibular aqueduct syndrome (LVAS). Background: LVAS is defined by the pathognomonic features of a widened bony vestibular aqueduct (VA) and an enlarged ES. The underlying cause of its associated cochleovestibular symptoms remains elusive. Disturbances in epithelial ion transport in the enlarged ES, affecting inner ear fluid regulation, were proposed as a possible pathophysiology....
Objective: To determine the cost-effectiveness of unilateral and bilateral cochlear implantation (CI) for children suffering from bilateral profound SNHL. Study Design: This was a cost benefit analysis study where quality-adjusted life years (QALY) and the expenditure involved post unilateral and bilateral CI were calculated to assess the cost per QALY gained. Setting: The study was conducted in a tertiary-care hospital in a city of a developing country. Patients: A...
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Publication date: November 2020Source: International Journal of Pediatric Otorhinolaryngology, Volume 138Author(s): Kayce L. Booth, Dylan A. Levy, David R. White, Jeremy D. Meier, Phayvanh P. Pecha
Publication date: November 2020Source: International Journal of Pediatric Otorhinolaryngology, Volume 138Author(s): Andrew J. Redmann, J. Paul Willging, Brianne B. Roby
Publication date: November 2020Source: International Journal of Pediatric Otorhinolaryngology, Volume 138Author(s): Habie Thomas Samuel, Lalee Varghese, Regi Kurien, Meera Thomas
Publication date: November 2020Source: International Journal of Pediatric Otorhinolaryngology, Volume 138Author(s): Min Sik Kim, Seong Wook Choi, Sang Hyo Lee, Jae Woo Lee, Il Woo Lee, Hyun Min Lee
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ABSTRACT BackgroundNeurosurgery has exceptionally high requirements for minimally invasive and safety. This survey attempts to analyze the practical application of AR in neurosurgical navigation. Also, this survey describes future trends in augmented reality neurosurgical navigation systems.MethodsIn this survey, we searched related keywords "augmented reality", "virtual reality", "neurosurgery", "surgical simulation", "brain tumor surgery", "neurovascular surgery", "temporal bone surgery", and...
Abstract Background and aimMost of the Mixed Reality models used in the surgical telepresence are suffering from the discrepancies in the boundary area and spatial‐temporal inconsistency due to the illumination variation in the video frames. The aim behind this work is to propose a new solution that helps produce the composite video by merging the augmented video of the surgery site and virtual hand of the remote expertise surgeon. The purpose of the proposed solution is to decrease the processing...
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Objectives The post‐traumatic ear deformity, known today as cauliflower ear, has been described since antiquity. It has long been associated with pugilistic sports (wrestling, boxing) as well as among the mentally ill. The aim of this study is to present the various terms used since antiquity to describe these traumatic deformations of the auricle and to trace the origin of the modern moniker “cauliflower ear.” Methods Historical study, only based on original documentation accessed through...
This case series examines interactive AR during minor otolaryngologic procedures. Although VR has been successfully used for pediatric vascular access, removing children from comforting people in the real world has resulted in patient anxiety. AR offers a potential advantage, utilizing distracting holographic images when patients maintain eye contact with parents. The primary objective was to determine the effect of AR on fear during pediatric otolaryngologic procedures. Secondary objectives included...
Objective To determine the impact of race and ethnicity on 30‐day complications following pediatric endoscopic sinus surgery (ESS). Study Design Cross‐sectional cohort study. Subjects and Methods Patients ≤ 18 years of age undergoing ESS from 2015 to 2017 were identified in the Pediatric National Surgical Improvement Program‐Pediatric database. Patient demographics, comorbidities, surgical indication, and postoperative complications were extracted. Patient race/ethnicity included non‐Hispanic...
Objectives/Hypothesis To characterize the head and neck cancer patients' lived experiences with survivorship through Instagram and examine opportunities for health professionals to provide support and outreach specifically targeting these needs. Study Design Descriptive observational study. Methods We analyzed key head and neck cancer–related hashtags by querying medical and layman terminology. The top English‐language posts for #headandneckcancer underwent further content examination...
Objectives To characterize tracheal cartilage morphology in mouse models of fibroblast growth factor receptor (Fgfr2)‐related craniosynostosis syndromes. To establish relationships between specific Fgfr2 mutations and tracheal cartilaginous sleeve (TCS) phenotypes in these mouse models. Methods Postnatal day 0 knock‐in mouse lines with disease‐specific genetic variations in the Fgfr2 gene (Fgfr2 C342Y/C342Y, Fgfr2 C342Y/+, Fgfr2 +/Y394C, Fgfr2 +/S252W, and Fgfr2 +/P253R) as well as line‐specific...
Objectives To investigate how the decision to report United States Medical Licensing Examination (USMLE) Step 1 score as pass/fail will influence future otolaryngology residency application and match processes. Study Design Survey study. Methods An anonymous and voluntary survey approved by the Otolaryngology Program Directors Organization was administered to academic faculty members from April 24, 2020 through May 19, 2020. Results Two hundred fifty‐seven surveys were received...
Objectives/Hypothesis Spin—the practice of adding or omitting information intentionally or unintentionally to make the results of a study more favorable—may influence clinical decision making, especially when present in study abstracts. Here, we quantify and characterize the presence of spin in the abstracts of systematic reviews regarding tonsillectomy. Methods This study is an analysis of systematic review abstracts. Searches were conducted on September 23, 2019 on PubMed and Embase using...
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