ABSTRACT Photodynamic therapy (PDT) has emerged as an interesting alternative option for onychomycosis treatment. The impact of a specific photosensitizer (PS) on the final result is an important factor to consider. We conducted a short‐ and medium‐term controlled trial to compare the effectiveness of PDT in the treatment of mild‐to‐moderate onychomycosis when it is mediated by two different PSs. Twenty patients were randomized to receive 9 sessions of PDT distributed over 16 weeks mediated either...
Abstract The safety of methotrexate in psoriasis patients with metabolic syndrome could be argued because of increased risk of liver toxicity. To investigate the safety of methotrexate compared to secukinumab in psoriasis patients with metabolic syndrome. A controlled, open trial in psoriasis patients with metabolic syndrome, candidate to methotrexate or secukinumab. Primary end point of the study was investigating any variations in waist circumference, body mass index, blood pressure, fasting glucose,...
Abstract A six‐year‐old child with recessive dystrophic epidermolysis bullosa, confirmed by history, clinical exam and antigen mapping, was treated with losartan with reduction in the blistering and better quality of life. This article is protected by copyright. All rights reserved.
Abstract Lichen sclerosus (LS) is a chronic relapsing, inflammatory skin disorder usually involving the anogenital region of both sexes lacking a resolutive therapy. This study compared adipose tissue derived‐stromal vascular fraction (AD‐SVF) and AD‐SVF‐enriched platelet‐rich plasma (PRP) therapy in the management of genital LS patients. Additionally, in vitro evaluation of cells and growth factors contained in the injected SVF have been evaluated as possible predictive factors for treatment outcome....
Abstract In 2017, the Food and Drug Administration approved dupilumab for patients with moderate to severe atopic dermatitis refractory to topical therapies; however, clinical trials specifically excluded patients with human immunodeficiency virus (HIV). Herein, we describe effective and uncomplicated treatment of atopic dermatitis with dupilumab over a 23‐month period in a patient with HIV. Throughout the treatment duration, the patient demonstrated marked improvement in atopic dermatitis severity,...
Abstract Introduction Er: YAG laser treatment has been used in resurfacing the acne scars for a long time, however, we could not find any study reporting the recovery rates after each session of the treatment. In this study, we aimed to report the improvement rates after each session. Materials and Methods We retrospectively analyzed the data of 35 patients with acne scars treated with fractional ablative Er: YAG laser. The patients received 1 to 4 sessions of treatment, with 4‐week intervals...
Abstract Hair loss can significantly impact an individual's psychological state, self‐image, and can lead to numerous personal, social, and occupational problems. Although these impairments are well documented in primary studies and reviews, and the need for appropriate psychological help is emphasized, there is still a lack of knowledge for a broader and specific picture. The patient's perspective is vital while seeking to understand the content of the variables like “impaired body image” or “low...
Abstract To evaluate the preventive practices in family members of melanoma patients regarding melanoma in Turkey and compare our results with similar studies by a literature review. A questionnaire‐based, cross‐sectional study was conducted in fifty‐two participants over the age of 18 years. The questionnaire consisted of the items regarding melanoma risk factors, sun protection behaviors, skin self‐examination (SSE) and family communication. Sun exposure (76.9%) and sunburns (69.2%) were relatively...
Abstract Androgenetic alopecia (AGA) is an androgen‐dependent hereditary trait resulting in hair miniaturization. It is the most common type of alopecia in men and women. During the last years multiple treatment modalities have been studied, but only topical minoxidil and finasteride have been approved by the U.S. Food and Drug Administration. Microneedling (MN) is a minimally invasive technique that induces collagen formation, as well as growth factors production and neovascularization. Even though...
Abstract COVID‐19 is a serious multisystem disease caused by severe acute respiratory syndrome coronavirus 2. Due to the COVID‐19 crisis, that still keeps its impacts worldwide, numerous scheduled medical activities have been postponed and this interruption has a potential to modify the management of many cutaneous conditions including pemphigus. This narrative review aims to discuss the management of pemphigus in the era of COVID‐19, considering the necessity to balance suitable pemphigus treatment...
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