Abstract Vascular disrupting agents disrupt tumour vessels, blocking the nutritional and oxygen supply tumours need to thrive. This is achieved by damaging the endothelium lining of blood vessels, resulting in red blood cells (RBCs) entering the tumour parenchyma. RBCs present in the extracellular matrix are exposed to external stressors resulting in biochemical and physiological changes. The detection of these changes can be used to monitor the efficacy of cancer treatments. Spectroscopic photoacoustic...
Sat Sep 05, 2020 14:44
Abstract Epilepsy is a yet under‐recognized consequence after a stroke and nearly 30% of cases are pharmacoresistant. There is an unmet need for therapeutic interventions during epileptogenesis for better long‐term disease outcomes. Transcranial photobiomodulation (PBM) and omega‐3 (Ω‐3) dietary supplementation are two approaches that have been shown promising neuroprotective effects after brain injuries. Here, we studied the PBM treatment or Ω‐3 diet during epileptogenesis in long‐term recurrent...
Sat Sep 05, 2020 14:44
Abstract Background The mummified body of a small child was found in a sealed Barstow cast iron casket during construction activity in San Francisco in 2016. Using historical records and ancient DNA the child was determined to be Edith H. Cook. She was born 28 November, 1873 in the city of San Francisco, and died of “marasmus” on 13 October, 1876 also in San Francisco. Aims Currently, there are few techniques for estimating human season of death in archaeological cases. Hydrogen...
Sat Sep 05, 2020 14:45
The aim of this systematic review and meta-analysis is to assess the degree of stability of anterior open bite (AOB) treatment performed through the molar intrusion supported with skeletal anchorage at least 1...
Sat Sep 05, 2020 03:00
Abstract The view that dominates the literature on intentional attitudes holds that beliefs and desires both have propositional content. A commitment to what I call “content uniformity” underlies this view. According to content uniformity, beliefs and desires are but different psychological modes having a uniform kind of content. Prima facie, the modes don’t place any constraint on the kinds of content the attitude can have. I challenge this consensus by pointing out an asymmetry...
Sun Sep 06, 2020 03:00
Plant extracts serve as reducing and coating agents and are, therefore, commonly employed for the generation of silver (Ag) nanoparticles (NPs). Plant extract mediated synthesis of Ag NPs is a green, environme...
Sat Sep 05, 2020 03:00
Staphylococcal protein A (SpA) is a major virulence factor of Staphylococcus aureus. S. aureus is able to escape detection by the immune system by the surface display of protein A. The SpA protein is broadly used...
Thu Sep 03, 2020 03:00
Cavitation microbubbles are imaged using a high-speed camera attached to a zoom lens. The experimental setup is explained, and image analysis is used to calculate the area of the cavitation. Image analysis is done using ImageJ.
Sat Sep 05, 2020 20:40
Purpose of review Food oral immunotherapy (OIT) has emerged as way to mitigate serious allergic reactions including life-threatening anaphylaxis related to accidental ingestion. However, gastrointestinal-related adverse effects of OIT have been reported and are often cited as reasons for discontinuation of therapy. We summarize recent research on the prevalence of eosinophilic esophagitis (EoE) in patients undergoing OIT. Recent findings We examined 12 recent studies on OIT for peanut, milk,...
Wed Sep 02, 2020 03:00
No abstract available
Tue Sep 01, 2020 03:00
Objective To determine the predictive computed tomography (CT) and clinical features for diagnosis of COVID-19 pneumonia. Methods The CT and clinical data including were analyzed using univariate analysis and multinomial logistic regression, followed by receiver operating characteristic curve analysis. Results The factors including size of ground grass opacity (GGO), GGO with reticular and/or interlobular septal thickening, vascular enlargement, “tree-in-bud” opacity, centrilobular nodules,...
Wed Sep 02, 2020 03:00
Clinical aggression episodes, that is aggression and externalising behaviours that create risk, in acute care hospitals are increasing. Acute care staff are often not confident or trained in the management of ...
Fri Sep 04, 2020 03:00
Internet- and mobile-based interventions (IMI) are an effective and scalable low-threshold solution to reach people who are undersupplied by current healthcare. Adapting interventions to the cultural and ethni...
Thu Sep 03, 2020 03:00
This systematic review aimed to investigate whether the administration of hypnotic medicines, z-drugs, melatonin or benzodiazepines, reduced pain intensity postoperatively.
Thu Sep 03, 2020 03:00
Integrated community case management (iCCM) is a community-based child health strategy designed to reduce deaths due to pneumonia, malaria, and diarrhea in low-income countries. Due to the integrated nature of...
Thu Sep 03, 2020 03:00
Abstract Background Both inflammatory bowel disease (IBD) and chronic rhinosinusitis (CRS) are characterized by dysregulated immune responses. Though previous studies have demonstrated the coexistence of IBD and CRS, investigations of their association using large sets of epidemiologic data are lacking. Methods We examined IBD and the subsequent risk of CRS in a nationwide setting. For January 1, 2000 to December 31, 2010, we identified in the National Health Insurance Dataset of Taiwan...
Fri Sep 04, 2020 21:44
Publication date: Available online 4 September 2020Source: American Journal of Infection ControlAuthor(s): Hiroki Kitagawa, Toshihito Nomura, Tanuza Nazmul, Omori Keitaro, Norifumi Shigemoto, Takemasa Sakaguchi, Hiroki Ohge
Sat Sep 05, 2020 13:48
In order to make a comparison of the age-specific ovarian cancer incidence rate between Japan and other countries, we abstracted cancer incidence rate from the cancer incidence in five continents Vol. XI (CI5) (1). The International Agency for Research on Cancer provides the CI5 databases on the incidence of cancer recorded by cancer registries (regional and national) worldwide. We used cancer incidence rates in five countries in Asia (China, India, Japan, Republic of Korea and Thailand), three countries...
Fri Aug 28, 2020 03:00
Healthcare workers (HCWs) are on the front line of the COVID-19 outbreak, and their constant exposure to infected patients and contaminated surfaces puts them at risk of acquiring and transmitting the infectio...
Fri Sep 04, 2020 03:00
Appropriate hand hygiene (HH) is key to reducing healthcare-acquired infections. The World Health Organization (WHO) recommends education and training to improve HH knowledge and compliance. Physicians are ran...
Thu Sep 03, 2020 03:00
Abstract The conclusions of the EFSA following the peer review of the initial risk assessments carried out by the competent authorities of the rapporteur Member State, France, and co‐rapporteur Member State, Latvia, for the pesticide active substance cyazofamid are reported. The context of the peer review was that required by Commission Implementing Regulation (EU) No 844/2012. The conclusions were reached on the basis of the evaluation of the representative uses of cyazofamid as a fungicide on...
Fri Sep 04, 2020 15:44
Journal of International Medical Research, Volume 48, Issue 9, September 2020. BackgroundPatients suffering from postoperative recurrent glioblastoma have an extremely unfavorable outcome because there are no proven therapeutic options. The median overall survival for those with relapsed glioblastoma after surgery is only 7.5 months.Case presentation: Between March 2015 and October 2019, a 44-year-old female patient with recurrent glioblastoma was treated by our medical team. After several failed...
Fri Sep 04, 2020 11:21
Journal of International Medical Research, Volume 48, Issue 9, September 2020. ObjectivesTo assess understudied, alternative suicide prevention modalities in a mental health care setting.MethodsThis was a prospective study of patients (n = 140, 68 cases and 72 controls) who were admitted to hospital or who contacted an SOS suicide crisis line for suicidal ideation or attempts. Psychiatric diagnoses (Mini-International Neuropsychiatric Interview) and intensity of anxiety/depression/suicidality (Hamilton...
Fri Sep 04, 2020 11:18
Journal of International Medical Research, Volume 48, Issue 9, September 2020. ObjectiveThere have been few studies on hematological parameters (e.g., hemoglobin, red cell distribution width, white blood cells, and mean platelet volume), and polycystic ovary syndrome (PCOS). This study aimed to compare hematological parameters between women with PCOS and controls.MethodsWe performed an age-matched case–control study in Faisal bin Mishal Center for Infertility, Buraidah (Kingdom of Saudi Arabia)....
Fri Sep 04, 2020 10:53
Journal of International Medical Research, Volume 48, Issue 9, September 2020. Twelfth rib syndrome is a rare condition that causes severe pain in the loin. The diagnosis of this phenomenon is based on the patient’s medical history and physical examination findings. However, many clinicians still lack an understanding of the disease; this delays an accurate diagnosis, causing patients to experience prolonged pain without proper treatment. We herein describe a 72-year-old woman and a 47-year-old woman...
Fri Sep 04, 2020 10:49
Journal of International Medical Research, Volume 48, Issue 9, September 2020. Mastocytosis is an accumulation of clonal mast cells within tissues and it is most commonly caused by an activating mutation in the KIT gene. In this study, we report a neonatal case who presented with diffuse cutaneous mastocytosis (CM) at birth. In China, nine other cases of neonatal-onset CM have been reported in the literature since 2006. In those cases, diffuse CM and urticaria pigmentosa were the main symptoms, and...
Fri Sep 04, 2020 10:46
Journal of International Medical Research, Volume 48, Issue 9, September 2020. Visual loss after spine surgery in the prone position is a disastrous postoperative complication because it is almost irreversible. Additionally, the optimal treatments and recommended professional guidelines for visual loss after spine surgery are deficient. A 43-year-old man developed visual loss after spine surgery in the prone position. Immediate ophthalmic consultation confirmed central retinal artery occlusion. Therefore,...
Fri Sep 04, 2020 10:35
Journal of International Medical Research, Volume 48, Issue 9, September 2020. ObjectivesTo investigate the prevalence of self-reported pain-related temporomandibular disorders (TMDs) and its association with psychological status in a dental clinic setting.MethodsIn this cross-sectional study, patients were asked to complete a TMD pain screener and the Patient Health Questionnaire-4 (PHQ-4). Correlations between symptoms of pain-related TMDs and PHQ-4 scores were analysed using Spearman’s correlation...
Fri Sep 04, 2020 10:31
Lymphadenopathy is common in patients with immunoglobulin G4-related disease (IgG4-RD). However, the described histopathologic features of IgG4-related lymphadenopathy have been shown to be largely nonspecific. In an attempt to identify features specific for nodal IgG4-RD we examined the histopathologic features of lymph nodes from 41 patients with established IgG4-RD, with comparison to 60 lymph nodes from patients without known or subsequent development of IgG4-RD. An increase in immunoglobulin...
Tue Sep 01, 2020 03:00
Although diagnosis of high-grade uterine mesenchymal tumors (UMTs) exhibiting classic morphologic features is straightforward, diagnosis is more challenging in tumors in which prototypical features are poorly developed, focal, and/or coexist with features seen in other neoplasms. Here, we sought to define the repertoire of somatic genetic alterations in diagnostically challenging UMTs with myomelanocytic differentiation, including some reported as perivascular epithelioid cell tumors (PEComas). In...
Tue Sep 01, 2020 03:00
Abstract Introduction Expectant and parenting young people (young parents) require diverse services to support their health, educational success, and family functioning. Rarely can the needs of young parents be met by a single school or service provider. This case study examines how one large school district funded through the pathways to success initiative was able to facilitate systems change to increase young parents’ access to and...
Sat Sep 05, 2020 03:00
Abstract Introduction Expectant and parenting young people (young parents) need a range of supports but may have difficulty accessing existing resources. An optimally connected network of organizations can help young parents navigate access to available services. Community organizations participating in the Pathways to Success (Pathways) initiative sought to strengthen their network of support for young parents through social network...
Sat Sep 05, 2020 03:00
Abstract Shared bicycle is an emerging form of public transportation in China and around the world. However, the bacterial community and drug-resistant microbiome on these bicycles have not been reported. Samples from 10 shared bicycles were observed by scanning electron microscopy (SEM). Nine samples collected from 90 shared bicycles in three different kinds of location (hospital, metro station, shopping mall) were used for full-length 16S rDNA gene analysis to figure out the...
Sat Sep 05, 2020 03:00
Abstract How insect communities are assembled in nature remains largely unknown. In particular, whether habitat filtering or competition serves as the main mechanism in forming insect communities is rarely subject to an in-depth investigation. One bottleneck lies in the difficulty of species identification when dealing with a large number of diverse insects. However, high-throughput sequencing technology coupled with classic DNA barcoding offers a great opportunity to infer community...
Sat Sep 05, 2020 03:00
Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c02088
Fri Sep 04, 2020 07:00
Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c07167
Fri Sep 04, 2020 07:00
Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c07692
Fri Sep 04, 2020 07:00
Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c07761
Fri Sep 04, 2020 07:00
Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c07081
Fri Sep 04, 2020 07:00
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