Microorganisms, Vol. 8, Pages 1354: Impact of Ozone, Sex, and Gonadal Hormones on Bronchoalveolar Lavage Characteristics and Survival in SP-A KO Mice Infected with Klebsiella pneumoniae Microorganisms doi: 10.3390/microorganisms8091354 Authors: Chintan K. Gandhi Anatoly N. Mikerov Faryal Durrani Todd M. Umstead Sanmei Hu Guirong Wang David S. Phelps Joanna Floros Surfactant protein A (SP-A) plays an important role in innate immunity. The sex-dependent survival of...
Fri Sep 04, 2020 03:00
Microorganisms, Vol. 8, Pages 1352: Molecular Characterization of the Myoliquefactive Fish Parasite Kudoa mirabilis (Cnidaria, Kudoidae) from SE Indian Ocean and Its Phylogenetic Relationship with the Kudoa thyrsites Species Complex Microorganisms doi: 10.3390/microorganisms8091352 Authors: Lucilla Giulietti Egil Karlsbakk Paolo Cipriani Salome Daniel Shayo Julia E. Storesund Arne Levsen Myxosporean parasites of the genus Kudoa are fish parasites of great economic importance,...
Fri Sep 04, 2020 03:00
Microorganisms, Vol. 8, Pages 1357: Genomic and Transcriptome Analyses of a Thermophilic Bacterium Geobacillus stearothermophilus B5 Isolated from Compost Reveal Its Enzymatic Basis for Lignocellulose Degradation Microorganisms doi: 10.3390/microorganisms8091357 Authors: Mengmeng Wang Jiaxi Miao Xuanqing Wang Tuo Li Han Zhu Dongyang Liu Qirong Shen A lignocellulose-degrading strain isolated from thermophilic compost was identified as Geobacillus stearothermophilus B5,...
Fri Sep 04, 2020 03:00
Microorganisms, Vol. 8, Pages 1351: Mycoplasmas–Host Interaction: Mechanisms of Inflammation and Association with Cellular Transformation Microorganisms doi: 10.3390/microorganisms8091351 Authors: Francesca Benedetti Sabrina Curreli Davide Zella Mycoplasmas are the smallest and simplest self-replicating prokaryotes. Located everywhere in nature, they are widespread as parasites of humans, mammals, reptiles, fish, arthropods, and plants. They usually exhibiting organ and tissue...
Fri Sep 04, 2020 03:00
Microorganisms, Vol. 8, Pages 1350: Metagenomic and Metatranscriptomic Study of Microbial Metal Resistance in an Acidic Pit Lake Microorganisms doi: 10.3390/microorganisms8091350 Authors: Diana Ayala-Muñoz William D. Burgos Javier Sánchez-España Estelle Couradeau Carmen Falagán Jennifer L. Macalady Cueva de la Mora (CM) is an acidic, meromictic pit lake in the Iberian Pyrite Belt characterized by extremely high metal(loid) concentrations and strong gradients in oxygen,...
Fri Sep 04, 2020 03:00
Microorganisms, Vol. 8, Pages 1349: Modulating Wine Aromatic Amino Acid Catabolites by Using Torulaspora delbrueckii in Sequentially Inoculated Fermentations or Saccharomyces cerevisiae Alone Microorganisms doi: 10.3390/microorganisms8091349 Authors: M. Antonia Álvarez-Fernández Ilaria Carafa Urska Vrhovsek Panagiotis Arapitsas Yeasts are the key microorganisms that transform grape juice into wine, and nitrogen is an essential nutrient able to affect yeast cell growth, fermentation...
Fri Sep 04, 2020 03:00
Molecules, Vol. 25, Pages 4075: Preparation and Characterization of Two Immunogens and Production of Polyclonal Antibody with High Affinity and Specificity for Darunavir Molecules doi: 10.3390/molecules25184075 Authors: Ibrahim A. Darwish Abdulrahman A. Almehizia Awwad A. Radwan Rashed N. Herqash Darunavir (DRV) is a potent antiviral drug used for treatment of infections with human immunodeficiency virus (HIV). Effective and safe treatment with DRV requires its therapeutic drug...
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Molecules, Vol. 25, Pages 4073: Kaempferol as a Dietary Anti-Inflammatory Agent: Current Therapeutic Standing Molecules doi: 10.3390/molecules25184073 Authors: Waqas Alam Haroon Khan Muhammad Ajmal Shah Omar Cauli Luciano Saso Inflammation is a physiological response to different pathological, cellular or vascular damages due to physical, chemical or mechanical trauma. It is characterized by pain, redness, heat and swelling. Current natural drugs are carefully chosen as a...
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Molecules, Vol. 25, Pages 4072: Valorization of Sweet Lime Peel for the Extraction of Essential Oil by Solvent Free Microwave Extraction Enhanced with Ultrasound Pretreatment Molecules doi: 10.3390/molecules25184072 Authors: Yasir Arafat Ammar Altemimi Salam Adnan Ibrahim Laxmikant Shivnath Badwaik Essential oils of sweet lime peel, a waste by-product in the juice industry, were extracted using the vacuum assisted solvent free microwave extraction (VASFME) method. The effects...
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Molecules, Vol. 25, Pages 4074: Insight into Physicochemical, Rheological, and Antibacterial Properties of Chitosan Extracted from Antarctic krill: A Comparative Study Molecules doi: 10.3390/molecules25184074 Authors: Yuan Yuan Luzhi Chen Wenzheng Shi Zhihe Wang Hongcai Zhang In this work, physicochemical, rheological, and antibacterial properties of chitosan (CS) extracted from white shrimp (WS), giant river prawn (GP), and Antarctic krill (AK) were investigated. The results...
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Molecules, Vol. 25, Pages 4071: High-Resolution Mass Spectrometry-Based Approaches for the Detection and Quantification of Peptidase Activity in Plasma Molecules doi: 10.3390/molecules25184071 Authors: Elisa Maffioli Zhenze Jiang Simona Nonnis Armando Negri Valentina Romeo Christopher B. Lietz Vivian Hook Giuseppe Ristagno Giuseppe Baselli Erik B. Kistler Federico Aletti Anthony J. O’Donoghue Gabriella Tedeschi Proteomic technologies have identified...
Sun Sep 06, 2020 03:00
Molecules, Vol. 25, Pages 4070: Structure and Physical Properties of Cardamonin: A Spectroscopic and Computational Approach Molecules doi: 10.3390/molecules25184070 Authors: Iwona Budziak Marta Arczewska Daniel M. Kamiński This is the first study of the crystal structure of cardamonin (CA) confirmed using single-crystal XRD analysis. In the crystal lattice of CA, two symmetry independent molecules are linked by hydrogen bonds within the layers and by the π···π...
Sun Sep 06, 2020 03:00
Molecules, Vol. 25, Pages 4068: Optimal Production of Protein Hydrolysates from Monkfish By-Products: Chemical Features and Associated Biological Activities Molecules doi: 10.3390/molecules25184068 Authors: José Antonio Vázquez Araceli Menduíña Margarita Nogueira Ana I. Durán Noelia Sanz Jesus Valcarcel The aim of this work was the recovery of protein substrates from monkfish waste (heads and viscera) generated in the on-board processing of this species. Initially, the...
Sun Sep 06, 2020 03:00
Molecules, Vol. 25, Pages 4069: Antibacterial Activity of Bacterial Cellulose Loaded with Bacitracin and Amoxicillin: In Vitro Studies Molecules doi: 10.3390/molecules25184069 Authors: Georgiana-Mădălina Lemnaru (Popa) Roxana Doina Truşcă Cornelia-Ioana Ilie Roxana Elena Țiplea Denisa Ficai Ovidiu Oprea Anicuța Stoica-Guzun Anton Ficai Lia-Mara Dițu The use of bacterial cellulose (BC) in skin wound treatment is very attractive due to its unique characteristics....
Sun Sep 06, 2020 03:00
Molecules, Vol. 25, Pages 4067: A Brief Overview of Dietary Zeaxanthin Occurrence and Bioaccessibility Molecules doi: 10.3390/molecules25184067 Authors: Cristina Tudor Adela Pintea As it exhibits no provitamin A activity, the dietary intake of zeaxanthin is not considered essential. However, its contribution to ocular health has long been acknowledged. Numerous publications emphasize the importance of zeaxanthin alongside lutein in ocular diseases such as cataracts and age-related...
Sun Sep 06, 2020 03:00
Molecules, Vol. 25, Pages 4066: Composition of Triterpenoids in Inonotus obliquus and Their Anti-Proliferative Activity on Cancer Cell Lines Molecules doi: 10.3390/molecules25184066 Authors: Jaecheol Kim Si Chang Yang Ah Young Hwang Hyunnho Cho Keum Taek Hwang The objective of this study was to determine the composition of triterpenoids in the extracts from the inner and outer parts of Inonotus obliquus and to evaluate their anti-proliferative activity against cancer cell...
Sun Sep 06, 2020 03:00
Molecules, Vol. 25, Pages 4063: Interconnected Micro, Meso, and Macro Porous Activated Carbon from Bacterial Nanocellulose for Superior Adsorption Properties and Effective Catalytic Performance Molecules doi: 10.3390/molecules25184063 Authors: Arnon Khamkeaw Tatdanai Asavamongkolkul Tianpichet Perngyai Bunjerd Jongsomjit Muenduen Phisalaphong The porous carbon (bacterial cellulose (BC)-activated carbon (AC)(BA)) prepared via two-step activation of bacterial nanocellulose...
Sat Sep 05, 2020 03:00
Molecules, Vol. 25, Pages 4065: Synthesis, Anti-proliferative Activity, and Molecular Docking Study of New Series of 1,3-5-Triazine Schiff Base Derivatives Molecules doi: 10.3390/molecules25184065 Authors: Hessa H. Al Rasheed Azizah M. Malebari Kholood A. Dahlous Darren Fayne Ayman El-Faham Based on the use of s-triazine as a scaffold, we report here a new series of s-triazine Schiff base derivatives and their anti-proliferative activity against two cancer cell lines: human...
Sat Sep 05, 2020 03:00
Molecules, Vol. 25, Pages 4064: Synthesis, In Silico and In Vitro Evaluation of Some Flavone Derivatives for Acetylcholinesterase and BACE-1 Inhibitory Activity Molecules doi: 10.3390/molecules25184064 Authors: Thai-Son Tran Thanh-Dao Tran The-Huan Tran Thanh-Tan Mai Ngoc-Le Nguyen Khac-Minh Thai Minh-Tri Le Acetylcholinesterase (AChE) and β-secretase (BACE-1) have become attractive therapeutic targets for Alzheimer’s disease (AD). Flavones are flavonoid...
Sat Sep 05, 2020 03:00
Molecules, Vol. 25, Pages 4058: Retrofractamide C Derived from Piper longum Alleviates Xylene-Induced Mouse Ear Edema and Inhibits Phosphorylation of ERK and NF-κB in LPS-Induced J774A.1 Molecules doi: 10.3390/molecules25184058 Authors: Hyung Jin Lim Seon Gyeong Bak Eun Jae Park Sae-Kwang Ku Soyoung Lee Seung Woong Lee Kang Min Lee Seung-Jae Lee Mun-Chual Rho Many studies have reported the biological activities of retrofractamide C (RAC). However, few studies...
Sat Sep 05, 2020 03:00
Molecules, Vol. 25, Pages 4062: Evaluation of Two Major Rhodiola Species and the Systemic Changing Characteristics of Metabolites of Rhodiola crenulata in Different Altitudes by Chemical Methods Combined with UPLC-QqQ-MS-Based Metabolomics Molecules doi: 10.3390/molecules25184062 Authors: Dong Guo Xiong Sun Rhodiola species have a long history of use in traditional medicine in Asian and European countries and have been considered to possess resistance to the challenges...
Sat Sep 05, 2020 03:00
Molecules, Vol. 25, Pages 4061: Study of Dispersions of Carbon Nanotubes Modified by the Method of Rapid Expansion of Supercritical Suspensions Molecules doi: 10.3390/molecules25184061 Authors: Konstantin B. Ustinovich Victor V. Ivanov Yurij M. Tokunov Alexander A. Loshkarev Natalya I. Sapronova Anton M. Vorobei Olga O. Parenago Michael G. Kiselev The effectiveness of carbon nanotubes (CNT) deagglomeration by rapid expansion of supercritical suspensions (RESS) in...
Sat Sep 05, 2020 03:00
Molecules, Vol. 25, Pages 4060: Optimization of Extraction Conditions for Gracilaria gracilis Extracts and Their Antioxidative Stability as Part of Microfiber Food Coating Additives Molecules doi: 10.3390/molecules25184060 Authors: João Reboleira Rui Ganhão Susana Mendes Pedro Adão Mariana Andrade Fernanda Vilarinho Ana Sanches-Silva Dora Sousa Artur Mateus Susana Bernardino Incorporation of antioxidant agents in edible films and packages often relies in the...
Sat Sep 05, 2020 03:00
Molecules, Vol. 25, Pages 4059: Microwave-Assisted Synthesis of Fluorescent Pyrido[2,3-b]indolizines from Alkylpyridinium Salts and Enaminones Molecules doi: 10.3390/molecules25184059 Authors: Ekaterina A. Sokolova Alexey A. Festa Karthikeyan Subramani Victor B. Rybakov Alexey V. Varlamov Leonid G. Voskressensky Erik V. Van der Eycken Pyridinium ylides are well recognized as dipoles for cycloaddition reactions. In its turn, the microwave-assisted interaction of N-(cyanomethyl)-2-alkylpyridinium...
Sat Sep 05, 2020 03:00
Molecules, Vol. 25, Pages 4057: Chiral Recognition of Flexible Melatonin Receptor Ligands Induced by Conformational Equilibria Molecules doi: 10.3390/molecules25184057 Authors: Gian Marco Elisi Annalida Bedini Laura Scalvini Caterina Carmi Silvia Bartolucci Valeria Lucini Francesco Scaglione Marco Mor Silvia Rivara Gilberto Spadoni N-anilinoethylamides are a class of melatoninergic agents with the aniline portion mimicking the indole ring of the natural ligand...
Fri Sep 04, 2020 03:00
Molecules, Vol. 25, Pages 4056: Tetrel Bonding and Other Non-Covalent Interactions Assisted Supramolecular Aggregation in a New Pb(II) Complex of an Isonicotinohydrazide Molecules doi: 10.3390/molecules25184056 Authors: Ghodrat Mahmoudi Marjan Abedi Simon E. Lawrence Ennio Zangrando Maria G. Babashkina Axel Klein Antonio Frontera Damir A. Safin A new supramolecular Pb(II) complex [PbL(NO2)]n was synthesized from Pb(NO3)2, N’-(1-(pyridin-2-yl)ethylidene)isonicotinohydrazide...
Fri Sep 04, 2020 03:00
Molecules, Vol. 25, Pages 4055: Evaluation of Antioxidant and Anti-Inflammatory Activity of Anthocyanin-Rich Water-Soluble Aronia Dry Extracts Molecules doi: 10.3390/molecules25184055 Authors: Mariusz Banach Magdalena Wiloch Katarzyna Zawada Wojciech Cyplik Wojciech Kujawski Aronia fruits contain many valuable components that are beneficial to human health. However, fruits are characterized by significant variations in chemical composition dependent on the growing conditions...
Fri Sep 04, 2020 03:00
Molecules, Vol. 25, Pages 4052: NBO/NRT Two-State Theory of Bond-Shift Spectral Excitation Molecules doi: 10.3390/molecules25184052 Authors: Yinchun Jiao Frank Weinhold We show that natural bond orbital (NBO) and natural resonance theory (NRT) analysis methods provide both optimized Lewis-structural bonding descriptors for ground-state electronic properties as well as suitable building blocks for idealized “diabatic” two-state models of the associated spectroscopic...
Fri Sep 04, 2020 03:00
Molecules, Vol. 25, Pages 4053: Functionalization of Magnetic Nanoparticles by Folate as Potential MRI Contrast Agent for Breast Cancer Diagnostics Molecules doi: 10.3390/molecules25184053 Authors: Hamid Heydari Sheikh Hossein Iraj Jabbari Atefeh Zarepour Ali Zarrabi Milad Ashrafizadeh Afrooz Taherian Pooyan Makvandi In recent years, the intrinsic magnetic properties of magnetic nanoparticles (MNPs) have made them one of the most promising candidates for magnetic resonance...
Fri Sep 04, 2020 03:00
Molecules, Vol. 25, Pages 4054: Antimicrobial Activity of Gemini Surfactants with Azapolymethylene Spacer Molecules doi: 10.3390/molecules25184054 Authors: Iwona Kowalczyk Marta Pakiet Adrianna Szulc Anna Koziróg A series of 21 azapolymethylene gemini surfactants were obtained. The synthesis of the title surfactants in one- or two-step reaction proceeds with good yields. The structure and the purity of the synthesized compounds were determined by 1H and 13C NMR, ESI-MS spectra,...
Fri Sep 04, 2020 03:00
Molecules, Vol. 25, Pages 4050: Biomass-Derived Porous Carbons Derived from Soybean Residues for High Performance Solid State Supercapacitors Molecules doi: 10.3390/molecules25184050 Authors: Hsiu-Ying Chung Guan-Ting Pan Zhong-Yun Hong Chun-Tsung Hsu Siewhui Chong Thomas Chung-Kuang Yang Chao-Ming Huang A series of heteroatom-containing porous carbons with high surface area and hierarchical porosity were successfully prepared by hydrothermal, chemical activation, and...
Fri Sep 04, 2020 03:00
Molecules, Vol. 25, Pages 4051: Anti-Inflammatory Effects of a Cordyceps sinensis Mycelium Culture Extract (Cs-4) on Rodent Models of Allergic Rhinitis and Asthma Molecules doi: 10.3390/molecules25184051 Authors: Jihang Chen Wing Man Chan Hoi Yan Leung Pou Kuan Leong Choly Tat Ming Yan Kam Ming Ko Allergic rhinitis and asthma are common chronic allergic diseases of the respiratory tract, which are accompanied by immunoglobulin E (IgE)-mediated inflammation and the involvement...
Fri Sep 04, 2020 03:00
Molecules, Vol. 25, Pages 4049: The Potential of Algal Biotechnology to Produce Antiviral Compounds and Biopharmaceuticals Molecules doi: 10.3390/molecules25184049 Authors: Sergio Rosales-Mendoza Ileana García-Silva Omar González-Ortega José M. Sandoval-Vargas Ashwini Malla Sornkanok Vimolmangkang The emergence of the Coronavirus Disease 2019 (COVID-19) caused by the SARS-CoV-2 virus has led to an unprecedented pandemic, which demands urgent development of antiviral drugs...
Fri Sep 04, 2020 03:00
Molecules, Vol. 25, Pages 4045: Nanocellulose Hybrids with Metal Oxides Nanoparticles for Biomedical Applications Molecules doi: 10.3390/molecules25184045 Authors: Madalina Oprea Denis Mihaela Panaitescu Cellulose is one of the most affordable, sustainable and renewable resources, and has attracted much attention especially in the form of nanocellulose. Bacterial cellulose, cellulose nanocrystals or nanofibers may serve as a polymer support to enhance the effectiveness of metal nanoparticles....
Fri Sep 04, 2020 03:00
Molecules, Vol. 25, Pages 4047: Reducing the Competition: A Dual-Purpose Ionic Liquid for the Extraction of Gallium from Iron Chloride Solutions Molecules doi: 10.3390/molecules25184047 Authors: Luke M. M. Kinsman Carole A. Morrison Bryne T. Ngwenya Jason B. Love The separation of gallium from iron by solvent extraction from chloride media is challenging because the anionic chloridometalates, FeCl4− and GaCl4−, display similar chemical properties. However,...
Fri Sep 04, 2020 03:00
Molecules, Vol. 25, Pages 4046: Flame-Retardant Systems Based on Chitosan and Its Derivatives: State of the Art and Perspectives Molecules doi: 10.3390/molecules25184046 Authors: Giulio Malucelli During the last decade, the utilization of chitin, and in par0ticular its deacetylated form, i.e. chitosan, for flame retardant purposes, has represented quite a novel and interesting application, very far from the established uses of this bio-sourced material. In this context, chitosan is a...
Fri Sep 04, 2020 03:00
Molecules, Vol. 25, Pages 4040: Structure and Function of the Human Ryanodine Receptors and Their Association with Myopathies—Present State, Challenges, and Perspectives Molecules doi: 10.3390/molecules25184040 Authors: Vladena Bauerová-Hlinková Dominika Hajdúchová Jacob A. Bauer Cardiac arrhythmias are serious, life-threatening diseases associated with the dysregulation of Ca2+ influx into the cytoplasm of cardiomyocytes. This dysregulation often arises from dysfunction of ryanodine...
Fri Sep 04, 2020 03:00
Molecules, Vol. 25, Pages 4043: Synthesis, Characterization, Catalytic Activity, and DFT Calculations of Zn(II) Hydrazone Complexes Molecules doi: 10.3390/molecules25184043 Authors: Temiloluwa T. Adejumo Nikolaos V. Tzouras Leandros P. Zorba Dušanka Radanović Andrej Pevec Sonja Grubišić Dragana Mitić Katarina K. Anđelković Georgios C. Vougioukalakis Božidar Čobeljić Iztok Turel Two new Zn(II) complexes with tridentate hydrazone-based ligands (condensation...
Fri Sep 04, 2020 03:00
Molecules, Vol. 25, Pages 4048: Noncovalent Complexes of Cyclodextrin with Small Organic Molecules: Applications and Insights into Host–Guest Interactions in the Gas Phase and Condensed Phase Molecules doi: 10.3390/molecules25184048 Authors: Jae-ung Lee Sung-Sik Lee Sungyul Lee Han Bin Oh Cyclodextrins (CDs) have drawn a lot of attention from the scientific communities as a model system for host–guest chemistry and also due to its variety of applications in the pharmaceutical,...
Fri Sep 04, 2020 03:00
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