Τετάρτη 11 Μαρτίου 2020


Sample study protocol for adapting and translating the 5C scale to assess the psychological antecedents of vaccination
IntroductionPublished in 2018, the 5C scale is psychometrically validated to assess five psychological antecedents of vaccination (confidence, complacency, constraints, calculation and collective responsibility). The original version offers a validated English and German scale to assess these determinants with a short 5-item scale (1 item per antecedent) and a long 15-item scale (3 items per antecedent). This sample study protocol provides a step-by-step guidance for the process of adapting the 5C...
BMJ Open Current Issue
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Pattern of corneal astigmatism induced by primary pterygium in patients with cataract in a secondary hospital in Southern China: a cross-sectional study
ObjectivesTo review the pattern of primary pterygium-induced corneal astigmatism in patients with cataract in a southern Chinese population. DesignClinic-based cross-sectional retrospective study. SettingA secondary hospital at southern China. ParticipantsA group of 1689 eyes with primary pterygium (PT group) and the other group of 4062 eyes without pterygium (NPT group) were included. Main outcome measuresCorneal power was measured by an autokeratorefractometer. Corneal astigmatism was calculated...
BMJ Open Current Issue
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Effect of resting heart rate on the risk of all-cause death in Chinese patients with hypertension: analysis of the Kailuan follow-up study
ObjectivePrevious studies have shown that an elevated heart rate is associated with a higher risk of cardiovascular events. This study aimed to prospectively examine the relationship between resting heart rate (RHR) and all-cause mortality in Chinese patients with hypertension. DesignAn observational, prospective and population-based cohort study. SettingThe Kailuan cohort study was conducted in Tangshan City in northern China. ParticipantsWe enrolled 46 561 patients who did not receive beta-blocker...
BMJ Open Current Issue
2h
Attitudes of patients and surgeons towards sham surgery trials: a protocol for a scoping review of attributes to inform a discrete choice experiment
IntroductionIn order to properly evaluate the efficacy of orthopaedic procedures, rigorous, randomised controlled sham surgery trial designs are necessary. However, randomised controlled trials (RCTs) for surgery involving a placebo are ethically debated and difficult to conduct with many failing to reach their desired sample size and power. A review of the literature on barriers and enablers to recruitment, and patient and surgeon attitudes and preferences towards sham surgery trials, will help...
BMJ Open Current Issue
2h
Continuing professional development requirements for UK health professionals: a scoping review
ObjectivesThis paper sets out to establish the numbers and titles of regulated healthcare professionals in the UK and uses a review of how continuing professional development (CPD) for health professionals is described internationally to characterise the postqualification training required of UK professions by their regulators. It compares these standards across the professions and considers them against the best practice evidence and current definitions of CPD. DesignA scoping review. Search...
BMJ Open Current Issue
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Constructing treatment episodes from concomitant medication logs: a prospective observational study
ObjectivesTo describe an approach using concomitant medication log records for the construction of treatment episodes. Concomitant medication log records are routinely collected in clinical studies. Unlike prescription and dispensing records, concomitant medication logs collect utilisation data. Logs can provide information about drug safety and drug repurposing. DesignA prospective multicentre, multicohort observational study. SettingTwenty-one clinical sites in the USA, Europe, Israel and Australia....
BMJ Open Current Issue
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Supporting the emotional needs of young people in care: a qualitative study of foster carer perspectives
ObjectivesYoung people who have been removed from their family home and placed in care have often experienced maltreatment and there is well-developed evidence of poor psychological outcomes. Once in care, foster carers often become the adult who provides day-to-day support, yet we know little about how they provide this support or the challenges to and facilitators of promoting better quality carer–child relationships. The aim of this study was to understand how carers support the emotional needs...
BMJ Open Current Issue
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Identifying and overcoming barriers to automated external defibrillator use by GoodSAM volunteer first responders in out-of-hospital cardiac arrest using the Theoretical Domains Framework and Behaviour Change Wheel: a qualitative study
ObjectivesGoodSAM is a mobile phone app that integrates with UK ambulance services. During a 999 call, if a call handler diagnoses cardiac arrest, nearby volunteer first responders registered with the app are alerted. They can give cardiopulmonary resuscitation (CPR) and/or use a public access automated external defibrillator (AED). We aimed to identify means of increasing AED use by GoodSAM first responders. MethodsWe conducted semistructured telephone interviews, using the Theoretical Domains...
BMJ Open Current Issue
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Association of intrinsic and extrinsic motivating factors with physician burnout and job satisfaction: a nationwide cross-sectional survey in Taiwan
ObjectiveThe aim of this study was to systematically and simultaneously examine the association of intrinsic and extrinsic motivating factors with physician burnout and job dissatisfaction. DesignA nationally representative survey was fielded from September to November 2017. SettingHospitals and clinics throughout Taiwan. ParticipantsA total of 6674 physicians. Main exposure measureThe main exposure measures were intrinsic motivators (sense of calling, personally rewarding hours per day and...
BMJ Open Current Issue
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Identifying values and preferences around the choice of analgesia for patients with acute trauma pain in emergency and prehospital settings: using group concept mapping methodology
ObjectivesThe main study aim was to examine the applicability of a novel method to assess the criterion of values and preferences within the Grading of Recommendation, Assessment, Development and Evaluation evidence to decision framework. The group concept mapping (GCM) approach was applied to identify, organise and prioritise values and preferences in the example of health professionals’ choice of analgesia for patients with acute trauma pain. SettingPrehospital and emergency care centres in the...
BMJ Open Current Issue
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Knowledge and perspectives of the new National Cervical Screening Program: a qualitative interview study of North Queensland women--'I could be that one percent
ObjectivesTo investigate women’s understanding and attitudes towards the National Cervical Screening Program (NCSP) and to explore methods to improve screening participation. DesignSemi-structured face-to-face interviews were conducted through convenience and snowball sampling. Thematic analysis occurred using the interpretivist framework. SettingA private general practice in North Queensland. ParticipantsWomen between the ages of 18 and 74 who attended the general practice were eligible to...
BMJ Open Current Issue
17h
Cohort profile: social well-being and determinants of health study (SWADES), Kerala, India
PurposeIn response to the need for more advanced and longitudinal data concerning chronic diseases, behavioural risk factors and social support systems in India, the SWADES (Social Well-being and Determinants of Health Study) was established. ParticipantsAt baseline, 997 adults aged 30 years and over, living in the semi-urban area were interviewed in their home. Findings to dateData collected included self-reports of demographic details, health, depression, morbid conditions and healthcare utilisation,...
BMJ Open Current Issue
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Psychometric properties of the Breast Cancer Awareness Measurement among Chinese women: a cross-sectional study
ObjectivesTo perform the cross-cultural adaption of the Breast Cancer Awareness Measurement (BCAM) and to test its psychometric properties among Chinese women. DesignThis is a cross-sectional study. SettingsThis study was conducted in communities, schools and institutions in Changchun, Jilin Province, China. ParticipantsA total of 328 women voluntarily participated in and completed the Chinese version of the BCAM (C-BCAM), resulting in an effective response rate of 91.1%. Primary and secondary...
BMJ Open Current Issue
17h
Duration of sick leave after active surveillance, surgery or radiotherapy for localised prostate cancer: a nationwide cohort study
ObjectivesTo compare the loss of working time due to sick leave by treatment strategy for localised prostate cancer. DesignNationwide cohort study. SettingSweden. ParticipantsA total of 15 902 working-aged men with localised low or intermediate-risk prostate cancer diagnosed during 2007–2016 from the Prostate Cancer Data Base Sweden, together with 63 464 prostate cancer-free men. Men were followed until 2016. Primary and secondary outcome measuresUsing multistate Markov models, we calculated...
BMJ Open Current Issue
17h
Determinants of overweight/obesity among reproductive age group women in Ethiopia: multilevel analysis of Ethiopian demographic and health survey
ObjectiveOverweight/obesity among women is associated with an increased risk of gestational diabetes, pre-eclampsia, postpartum haemorrhage, low birth weight, congenital malformation and neonatal deaths. Although the magnitude of overweight and obesity among the reproductive age group women is a common problem in Ethiopia, there are limited studies that determine the associated factors of overweight and obesity at the national level. Therefore, this study aimed to identify the determinant factors...
BMJ Open Current Issue
17h
Pharmacologic and non-pharmacologic interventions to prevent hypersensitivity reactions of non-ionic iodinated contrast media: a systematic review protocol
IntroductionIodinated contrast media are commonly used in medical imaging and can cause hypersensitivity reactions, including rare but severe life-threatening reactions. Although several prophylactic approaches have been proposed for severe reactions, their effects remain unclear. Therefore, we aim to review systematically the preventive effects of pharmacologic and non-pharmacologic interventions and predictors of acute, hypersensitivity reactions. Methods and analysisWe will search the PubMed,...
BMJ Open Current Issue
17h
Do recent immigrants have similar obstetrical care and perinatal complications as long-term residents? A retrospective exploratory cohort study in Brussels
PurposeRecent immigrants (RIs) face various barriers affecting quality of care. The main research question assessed whether perinatal complications (during pregnancy, labour, delivery and neonatal period) were similar in RIs to those in long-term residents (LTRs). The secondary question assessed whether prenatal and perinatal care was similar in the two groups. MethodsThis is a monocentric observational study, carried out in Brussels between November 2016 and March 2017 (n=1365). We surveyed 892...
BMJ Open Current Issue
17h
Development and usability testing of HEARTPAfemaleN: protocol for a mixed methods strategy to develop an integrated smartphone and web-based intervention for women with cardiac pain
IntroductionMore women experience cardiac pain related to coronary artery disease and cardiac procedures compared with men. The overall goal of this programme of research is to develop an integrated smartphone and web-based intervention (HEARTPAN) to help women recognise and self-manage cardiac pain. Methods and analysisThis protocol outlines the mixed methods strategy used for the development of the HEARTPAN content/core feature set (phase 2A), usability testing (phase 2B) and evaluation with...
BMJ Open Current Issue
17h
Dissemination and implementation of the e-MCHHandbook, UNRWAs newly released maternal and child health mobile application: a cross-sectional study
ObjectivesIn April 2017, the United Nations Relief and Works Agency for Palestine Refugees in the Near East (UNRWA) released the electronic Maternal andChildHealth Handbook, the e-MCH Handbook application. One of the first mobile health (m-Health) interventions in a refugee setting, the application gives pregnant women and mothers access to educational information and health records on smartphones. This study investigated factors associated with the dissemination and implementation of m-Health in...
BMJ Open Current Issue
17h
Primary care patient and practitioner views of weight and weight-related discussion: a mixed-methods study
ObjectiveTo understand the beliefs that primary care practitioners (PCPs) and patients with overweight and obesity have about obesity and primary care weight management in Scotland. SettingSeven National Health Service (NHS) Scotland primary care centres. ParticipantsA total of 305 patients and 14 PCPs (12 general practitioners; two practice nurses) participated. Design and methodologyA cross-sectional mixed-methods study. PCPs and patients completed questionnaires assessing beliefs about obesity...
BMJ Open Current Issue
17h
Facilitators and barriers to the self-management of COPD: a qualitative study from rural Nepal
ObjectiveTo understand the facilitators and barriers to the self-management of chronic obstructive pulmonary disease (COPD) in rural Nepal. SettingsCommunity and primary care centres in rural Nepal. ParticipantsA total of 14 participants (10 people with COPD and 4 health care providers) were interviewed. Primary and secondary outcome measure(s)People with COPD and healthcare provider’s experience of COPD self-management in rural Nepal. ResultsFacilitators and barriers affecting COPD self-management...
BMJ Open Current Issue
17h
Evaluation of a complex integrated, cross-sectoral psycho-oncological care program (isPO): a mixed-methods study protocol
IntroductionInternational standards of care require the complete integration of psycho-oncological care into biomedical cancer treatment. The structured integrated, cross-sectoral psycho-oncological programme ‘isPO’ is aiming to ensure a provision of care in inpatient and outpatient settings according to a stepped-care approach. Up to now, psycho-oncological care is missing regulated and standardised processes to demonstrate the effectiveness. This study protocol describes the process and outcome...
BMJ Open Current Issue
17h
Identifying the predictors of avoidable emergency department attendance after contact with the NHS 111 phone service: analysis of 16.6 million calls to 111 in England in 2015-2017
ObjectivesTo measure the frequency of patients making avoidable emergency department (ED) attendances after contact with NHS 111 and to examine whether these attendances can be predicted reliably. DesignAnalysis of 16 563 946 calls made to 111, where each call was linked with a record of whether the patient attended ED within 24 hours. SettingAll regions of England from March 2015 to October 2017. Participants and dataOur main regression model used a sample of 10 954 783 calls, each with detailed...
BMJ Open Current Issue
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Correction: Postoperative intravenous parecoxib sodium followed by oral celecoxib post total knee arthroplasty in osteoarthritis patients (PIPFORCE): a multicentre, double-blind, randomised, placebo-controlled trial
Zhuang Q, Tao L, Lin J, et al. Postoperative intravenous parecoxib sodium followed by oral celecoxib post total knee arthroplasty in osteoarthritis patients (PIPFORCE): a multicentre, double-blind, randomised, placebo-controlled trial. BMJ Open 2020;10:e030501. doi: 10.1136/bmjopen-2019-030501 This article was previously published with missing information in authorship. Please note the below: Qianyu Zhuang and Liyuan Tao contribute equally to the paper.
BMJ Open Current Issue
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Correction: The premature closure of ROMPA clinical trial: mortality reduction in septic shock by plasma adsorption
Giménez-Esparza C, Portillo-Requena C, Colomina-Climent F, et al. The premature closure of ROMPA clinical trial: mortality reduction in septic shock by plasma adsorption. BMJ Open 2019;9:e030139. doi: 10.1136/bmjopen-2019-030139. This article was previously published with an error. The following statement in the discussion section is incorrect: ‘In addition, as in our study, the COMPACT 2 group used a randomisation system based on prognostic scores,6 which means that the groups will not be similar...
BMJ Open Current Issue
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