IJMS, Vol. 21, Pages 1915: Electrohypersensitivity as a Newly Identified and Characterized Neurologic Pathological Disorder: How to Diagnose, Treat, and Prevent It International Journal of Molecular Sciences doi: 10.3390/ijms21061915 Authors: Belpomme Irigaray Since 2009, we built up a database which presently includes more than 2000 electrohypersensitivity (EHS) and/or multiple chemical sensitivity (MCS) self-reported cases. This database shows that EHS is associated in 30% of...
Wed Mar 11, 2020 02:00
IJMS, Vol. 21, Pages 1916: In Situ Profiling of the Three Dominant Phyla Within the Human Gut Using TaqMan PCR for Pre-Hospital Diagnosis of Gut Dysbiosis International Journal of Molecular Sciences doi: 10.3390/ijms21061916 Authors: Jo Tagele Pham Jung Ibal Choi Kang Park Kang Kim Koh Shin A microbial imbalance called dysbiosis leads to inflammatory bowel disease (IBD), which can include ulcerative colitis (UC). Fecal microbiota transplantation...
Wed Mar 11, 2020 02:00
IJMS, Vol. 21, Pages 1912: Antifungal Activity of Anionic Defense Peptides: Insight into the Action of Galleria mellonella Anionic Peptide 2 International Journal of Molecular Sciences doi: 10.3390/ijms21061912 Authors: Aneta Sowa-Jasiłek Agnieszka Zdybicka-Barabas Sylwia Stączek Bożena Pawlikowska-Pawlęga Katarzyna Grygorczuk-Płaneta Krzysztof Skrzypiec Wiesław I. Gruszecki Paweł Mak Małgorzata Cytryńska Anionic antimicrobial peptides constitute an integral component...
Wed Mar 11, 2020 02:00
IJMS, Vol. 21, Pages 1911: Correlative Light and Electron Microscopy (CLEM) Analysis of Nuclear Reorganization Induced by Clustered DNA Damage Upon Charged Particle Irradiation International Journal of Molecular Sciences doi: 10.3390/ijms21061911 Authors: Tonnemacher Eltsov Jakob Chromatin architecture plays major roles in gene regulation as well as in the repair of DNA damaged by endogenous or exogenous factors, such as after radiation. Opening up the chromatin might provide...
Wed Mar 11, 2020 02:00
IJMS, Vol. 21, Pages 1907: Antidiabetic Therapy in the Treatment of Nonalcoholic Steatohepatitis International Journal of Molecular Sciences doi: 10.3390/ijms21061907 Authors: Yoshio Sumida Masashi Yoneda Katsutoshi Tokushige Miwa Kawanaka Hideki Fujii Masato Yoneda Kento Imajo Hirokazu Takahashi Yuichiro Eguchi Masafumi Ono Yuichi Nozaki Hideyuki Hyogo Masahiro Koseki Yuichi Yoshida Takumi Kawaguchi Yoshihiro Kamada Takeshi Okanoue Atsushi...
Wed Mar 11, 2020 02:00
IJMS, Vol. 21, Pages 1909: Identification of the Core Pollen-Specific Regulation in the Rice OsSUT3 Promoter International Journal of Molecular Sciences doi: 10.3390/ijms21061909 Authors: Dandan Li Rucong Xu Dong Lv Chunlong Zhang Hong Yang Jianbo Zhang Jiancheng Wen Chengyun Li Xuelin Tan The regulatory mechanisms of pollen development have potential value for applications in agriculture, such as better understanding plant reproductive regularity. Pollen-specific...
Wed Mar 11, 2020 02:00
IJMS, Vol. 21, Pages 1910: NR2F2 Orphan Nuclear Receptor is Involved in Estrogen Receptor Alpha-Mediated Transcriptional Regulation in Luminal A Breast Cancer Cells International Journal of Molecular Sciences doi: 10.3390/ijms21061910 Authors: Edina Erdős Bálint László Bálint Nuclear Receptor Subfamily 2 Group F Member 2 (NR2F2) is a member of the steroid/thyroid hormone receptor superfamily with a crucial role in organogenesis, angiogenesis, cardiovascular development and tumorigenesis....
Wed Mar 11, 2020 02:00
IJMS, Vol. 21, Pages 1908: Peripheral Circulating Exosomal miRNAs Potentially Contribute to the Regulation of Molecular Signaling Networks in Aging International Journal of Molecular Sciences doi: 10.3390/ijms21061908 Authors: Hongxia Zhang Kunlin Jin People are living longer than ever. Consequently, they have a greater chance for developing a functional impairment or aging-related disease, such as a neurodegenerative disease, later in life. Thus, it is important to identify and understand...
Wed Mar 11, 2020 02:00
IJMS, Vol. 21, Pages 1905: Natural Products Targeting ER Stress, and the Functional Link to Mitochondria International Journal of Molecular Sciences doi: 10.3390/ijms21061905 Authors: Stefania Martucciello Milena Masullo Antonietta Cerulli Sonia Piacente The endoplasmic reticulum (ER) is a dynamic organelle essential for intracellular homeostasis maintenance, controlling synthesis, the folding of secreted and membrane-bound proteins, and transport of Ca2+. During cellular stress,...
Wed Mar 11, 2020 02:00
IJMS, Vol. 21, Pages 1906: Novel Molecular Mechanisms of Gangliosides in the Nervous System Elucidated by Genetic Engineering International Journal of Molecular Sciences doi: 10.3390/ijms21061906 Authors: Koichi Furukawa Yuhsuke Ohmi Farhana Yesmin Orie Tajima Yuji Kondo Pu Zhang Noboru Hashimoto Yuki Ohkawa Robiul H. Bhuiyan Keiko Furukawa Acidic glycosphingolipids, i.e., gangliosides, are predominantly and consistently expressed in nervous tissues of vertebrates...
Wed Mar 11, 2020 02:00
JCM, Vol. 9, Pages 762: Physicians’ Disease Severity Ratings are Non-Inferior to the Emergency Severity Index Journal of Clinical Medicine doi: 10.3390/jcm9030762 Authors: Roland Bingisser Severin Manuel Baerlocher Tobias Kuster Ricardo Nieves Ortega Christian H. Nickel Our objective was to compare informal physicians’ disease severity ratings (PDSR) at presentation with the well-established Emergency Severity Index (ESI) in order to test for non-inferiority of...
Wed Mar 11, 2020 02:00
JCM, Vol. 9, Pages 760: Risk, Diagnostic and Predictor Factors for Classical Hodgkin Lymphoma in HIV-1-Infected Individuals: Role of Plasma Exosome-Derived miR-20a and miR-21 Journal of Clinical Medicine doi: 10.3390/jcm9030760 Authors: Francisco J. Hernández-Walias Esther Vázquez Yolanda Pacheco José M. Rodríguez-Fernández María J. Pérez-Elías Fernando Dronda José L. Casado Ana Moreno José M. Hermida Carmen Quereda Asunción Hernando Francisco Tejerina-Picado...
Wed Mar 11, 2020 02:00
JCM, Vol. 9, Pages 761: Primary Open Angle Glaucoma and Vascular Risk Factors: A Review of Population Based Studies from 1990 to 2019 Journal of Clinical Medicine doi: 10.3390/jcm9030761 Authors: Andrzej Grzybowski Mariusz Och Piotr Kanclerz Christopher Leffler Carlos Gustavo De Moraes Glaucoma is one of the leading causes of blindness worldwide, and as the proportion of those over age 40 increases, so will the prevalence of glaucoma. The pathogenesis of primary open angle...
Wed Mar 11, 2020 02:00
JCM, Vol. 9, Pages 759: Degenerative Cervical Myelopathy: How to Identify the Best Responders to Surgery? Journal of Clinical Medicine doi: 10.3390/jcm9030759 Authors: Rocco Severino Aria Nouri Enrico Tessitore Surgery is the only definitive treatment for degenerative cervical myelopathy (DCM), however, the degree of neurological recovery is often unpredictable. Here, we assess the utility of a multidimensional diagnostic approach, consisting of clinical, neurophysiological, and...
Wed Mar 11, 2020 02:00
JCM, Vol. 9, Pages 758: En-Bloc Resection of Metastases of the Proximal Femur and Reconstruction by Modular Arthroplasty is Not Only Justified in Patients with a Curative Treatment Option—An Observational Study of a Consecutive Series of 45 Patients Journal of Clinical Medicine doi: 10.3390/jcm9030758 Authors: Oliver E. Bischel Arnold J. Suda Paul M. Böhm Burkhard Lehner Rudi G. Bitsch Jörn B. Seeger Background: There is little conformity regarding the surgical treatment...
Wed Mar 11, 2020 02:00
JCM, Vol. 9, Pages 756: Associations between Disease Activity/Severity and Damage and Health-Related Quality of Life in Adult Patients with Localized Scleroderma—A Comparison of LoSCAT and Visual Analogue Scales Journal of Clinical Medicine doi: 10.3390/jcm9030756 Authors: Anna Lis-Święty Alina Skrzypek-Salamon Irmina Ranosz-Janicka Ligia Brzezińska-Wcisło Localized scleroderma (LoS) is a chronic fibrosing disorder of the skin and, less commonly, subcutaneous tissues. As the...
Wed Mar 11, 2020 02:00
JCM, Vol. 9, Pages 757: Cerebellar Astrocytes: Much More Than Passive Bystanders In Ataxia Pathophysiology Journal of Clinical Medicine doi: 10.3390/jcm9030757 Authors: Valentina Cerrato Ataxia is a neurodegenerative syndrome, which can emerge as a major element of a disease or represent a symptom of more complex multisystemic disorders. It comprises several forms with a highly variegated etiology, mainly united by motor, balance, and speech impairments and, at the tissue level, by cerebellar...
Wed Mar 11, 2020 02:00
JCM, Vol. 9, Pages 754: An Overview on Primary Sclerosing Cholangitis Journal of Clinical Medicine doi: 10.3390/jcm9030754 Authors: Cătălina Vlăduţ Mihai Ciocîrlan Dana Bilous Vasile Șandru Mădălina Stan-Ilie Nikola Panic Gabriel Becheanu Mariana Jinga Raluca S. Costache Daniel O. Costache Mircea Diculescu Primary sclerosing cholangitis is a progressive liver disease characterized by chronic inflammation leading to liver fibrosis and cirrhosis. Even though...
Wed Mar 11, 2020 02:00
JCM, Vol. 9, Pages 755: Improvement in Subjective Symptoms and Tolerability in Response to Nintedanib Treatment in Elderly Patients with Idiopathic Pulmonary Fibrosis Journal of Clinical Medicine doi: 10.3390/jcm9030755 Authors: Takayuki Takeda Yusuke Kunimatsu Nozomi Tani Izumi Hashimoto Yuri Kurono Kazuki Hirose The efficacy of nintedanib treatment in patients with idiopathic pulmonary fibrosis (IPF) was demonstrated in phase III trials. However, there is limited data...
Wed Mar 11, 2020 02:00
JCM, Vol. 9, Pages 753: Antibodies against Malondialdehyde in Haemodialysis Patients and Its Association with Clinical Outcomes: Differences between Subclasses and Isotypes Journal of Clinical Medicine doi: 10.3390/jcm9030753 Authors: Samal Qureshi Rahman Stenvinkel Frostegård Patients on haemodialysis (HD-patients) have an increased risk of premature death. Low levels of IgM antibodies against malondialdehyde (anti-MDA) are associated with increased risk of cardiovascular...
Wed Mar 11, 2020 02:00
JoF, Vol. 6, Pages 35: Applying the Host-Microbe Damage Response Framework to Candida Pathogenesis: Current and Prospective Strategies to Reduce Damage Journal of Fungi doi: 10.3390/jof6010035 Authors: Paul L. Fidel Junko Yano Shannon K. Esher Mairi C. Noverr Disease is a complex outcome that can occur as a result of pathogen-mediated damage, host-mediated damage or both. This has led to the revolutionary concept of the damage response framework (DRF) that defines microbial...
Wed Mar 11, 2020 02:00
Medical Sciences, Vol. 8, Pages 14: Implementation and Validation of the Roche Light Cycler 480 96-Well Plate Platform as a Real-Time PCR Assay for the Quantitative Detection of Cytomegalovirus (CMV) in Clinical Specimens Using the Luminex MultiCode ASRs System Medical Sciences doi: 10.3390/medsci8010014 Authors: Li Sparks Sender Allogenic stem-cell therapies benefit patients in the treatment of multiple diseases; however, the side effects of stem-cell therapies (SCT) derived...
Wed Mar 11, 2020 02:00
Medicina, Vol. 56, Pages 121: Sarcopenia is Independently Associated with an Increased Risk of Peptic Ulcer Disease: A Nationwide Population-Based Study Medicina doi: 10.3390/medicina56030121 Authors: Choi Chung Park Ko Kim Kwon Kim Kim Background and objective: Although obesity is associated with an increased risk of peptic ulcer disease (PUD), no study has evaluated the association of PUD with sarcopenia. The aim of this study was to evaluate the association...
Wed Mar 11, 2020 02:00
Membranes, Vol. 10, Pages 40: Effect of Surface Inhomogeneity of Ion-Exchange Membranes on the Mass Transfer Efficiency in Pulsed Electric Field Modes Membranes doi: 10.3390/membranes10030040 Authors: Butylskii Moroz Tsygurina Mareev Despite the growing interest in pulsed electric field modes in membrane separation processes, there are currently not many works devoted to studying the effect of the surface properties and composition of ion-exchange membranes on their efficiency...
Wed Mar 11, 2020 02:00
Metabolites, Vol. 10, Pages 101: Lipid Annotator: Towards Accurate Annotation in Non-Targeted Liquid Chromatography High-Resolution Tandem Mass Spectrometry (LC-HRMS/MS) Lipidomics Using A Rapid and User-Friendly Software Metabolites doi: 10.3390/metabo10030101 Authors: Jeremy P. Koelmel Xiangdong Li Sarah M. Stow Mark J. Sartain Adithya Murali Robin Kemperman Hiroshi Tsugawa Mikiko Takahashi Vasilis Vasiliou John A. Bowden Richard A. Yost Timothy J. Garrett...
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Metabolites, Vol. 10, Pages 100: An Untargeted Metabolomics Approach to Investigate the Metabolic Effect of Beetroot Juice Supplementation in Fencers—A Preliminary Study Metabolites doi: 10.3390/metabo10030100 Authors: Kozlowska Mizera Mroz This study aimed at assessment of the long-term (4 weeks) metabolic effect of a diet with and without beetroot juice supplementation in fencers using the untargeted metabolomics method with the UPLC Q-TOF/MS system to carry out an analysis...
Wed Mar 11, 2020 02:00
Microorganisms, Vol. 8, Pages 391: Effects of a Diet Supplemented with Exogenous Catalase from Penicillium notatum on Intestinal Development and Microbiota in Weaned Piglets Microorganisms doi: 10.3390/microorganisms8030391 Authors: Li Zhao Zhang Zhan Liu Zhuo Lin Fang Che Feng Xu Li Wu This study aims to investigate the effects of exogenous catalase (CAT), an antioxidative enzyme from microbial cultures, on intestinal development and...
Wed Mar 11, 2020 02:00
Microorganisms, Vol. 8, Pages 393: Screening of Bacteriocinogenic Lactic Acid Bacteria and Their Characterization as Potential Probiotics Microorganisms doi: 10.3390/microorganisms8030393 Authors: Pinto Barbosa Albano Isidro Teixeira Probiotics are living microorganisms used as nutritional additives that confer health benefits on the host. Their use in food products is very attractive, especially if they could also inhibit important foodborne pathogens. In this study,...
Wed Mar 11, 2020 02:00
Microorganisms, Vol. 8, Pages 392: Egyptian Mongoose (Herpestes ichneumon) Gut Microbiota: Taxonomical and Functional Differences across Sex and Age Classes Microorganisms doi: 10.3390/microorganisms8030392 Authors: Pereira Bandeira Fonseca Cunha The Egyptian mongoose (Herpestes ichneumon) is a medium-size carnivore that, in Europe, is restricted to Iberia. The bio-ecology of this species remains to be elucidated in several dimensions, including gut microbiota that is nowadays...
Wed Mar 11, 2020 02:00
Microorganisms, Vol. 8, Pages 394: Propionate Converting Anaerobic Microbial Communities Enriched from Distinct Biogeochemical Zones of Aarhus Bay, Denmark under Sulfidogenic and Methanogenic Conditions Microorganisms doi: 10.3390/microorganisms8030394 Authors: Ozuolmez Stams Plugge The relationship between predominant physiological types of prokaryotes in marine sediments and propionate degradation through sulfate reduction, fermentation, and methanogenesis was studied in marine...
Wed Mar 11, 2020 02:00
Microorganisms, Vol. 8, Pages 387: A Novel Lactic Acid Bacteria Mixture: Macrophage-Targeted Prophylactic Intervention in Colorectal Cancer Management Microorganisms doi: 10.3390/microorganisms8030387 Authors: Hradicka Beal Kassayova Foey Demeckova Colorectal cancer (CRC) is one of the most common forms of cancer. Its onset from chronic inflammation is widely accepted. Moreover, dysbiosis plays an undeniable role, thus the use of probiotics in CRC has been suggested....
Wed Mar 11, 2020 02:00
Microorganisms, Vol. 8, Pages 389: Molecular Dissection of the Campylobacter jejuni CadF and FlpA Virulence Proteins in Binding to Host Cell Fibronectin Microorganisms doi: 10.3390/microorganisms8030389 Authors: Talukdar Negretti Turner Konkel Campylobacter jejuni, a zoonotic pathogen that frequently colonizes poultry, possesses two Microbial Surface Components Recognizing Adhesive Matrix Molecule(s) (MSCRAMMs) termed CadF and FlpA that bind to the glycoprotein fibronectin...
Wed Mar 11, 2020 02:00
Microorganisms, Vol. 8, Pages 390: Galleria mellonella for the Evaluation of Antifungal Efficacy against Medically Important Fungi, a Narrative Review Microorganisms doi: 10.3390/microorganisms8030390 Authors: Jemel Guillot Kallel Botterel Dannaoui The treatment of invasive fungal infections remains challenging and the emergence of new fungal pathogens as well as the development of resistance to the main antifungal drugs highlight the need for novel therapeutic strategies....
Wed Mar 11, 2020 02:00
Microorganisms, Vol. 8, Pages 388: Human Herpesvirus 8 and Host‐Cell Interaction: Long-Lasting Physiological Modifications, Inflammation and Related Chronic Diseases Microorganisms doi: 10.3390/microorganisms8030388 Authors: Angius Ingianni Pompei Oncogenic and latent-persistent viruses belonging to both DNA and RNA groups are known to cause serious metabolism alterations. Among these, the Human Herpesvirus 8 (HHV8) infection induces stable modifications in biochemistry and...
Wed Mar 11, 2020 02:00
Molbank, Vol. 2020, Article M1120: (E)-1,1,1-Trifluoro-6,6-bis(4-methoxyphenyl)hexa-3,5-dien-2-one Molbank doi: 10.3390/M1120 Authors: Victorio Cadierno The title compound was obtained in high yield (84%) via the deacetylation of 3-(3,3-bis(4-methoxyphenyl)allylidene)-1,1,1,5,5,5-hexafluoro-2,4-pentanedione with K2CO3 in refluxing methanol. This previously unreported compound has been fully characterized by 19F{1H}, 1H and 13C{1H} NMR, IR, UV-Vis, and HRMS.
Wed Mar 11, 2020 02:00
Molecules, Vol. 25, Pages 1278: Simultaneous Determination of α-Glucosidase Inhibitory Triterpenoids in Psidium guajava Using HPLC–DAD–ELSD and Pressurized Liquid Extraction Molecules doi: 10.3390/molecules25061278 Authors: In-Cheng Chao Ying Chen Mei-Hua Gao Li-Gen Lin Xiao-Qi Zhang Wen-Cai Ye Qing-Wen Zhang Psidium guajava, a popular food and medicine dual purposes plant cultivated in tropical and subtropical regions, has been widely used as food crop and folk medicine,...
Wed Mar 11, 2020 02:00
Molecules, Vol. 25, Pages 1276: Phenolic Compounds, Antioxidant Activities, and Inhibitory Effects on Digestive Enzymes of Different Cultivars of Okra (Abelmoschus esculentus) Molecules doi: 10.3390/molecules25061276 Authors: Wu Nie Shen Li Zhao Zhang Lin Qin In this study, the phenolic profiles and bioactivities of five representative cultivars of okra collected in China were investigated. Noticeable variations of phenolic compounds and their bioactivities...
Wed Mar 11, 2020 02:00
Molecules, Vol. 25, Pages 1274: 1H-NMR Metabolomics Analysis of the Effect of Rubusoside on Serum Metabolites of Golden Hamsters on a High-Fat Diet Molecules doi: 10.3390/molecules25061274 Authors: Li Li Manjing Jiang Yaohua Li Jian Su Li Li Xiaosheng Qu Lanlan Fan Rubusoside is a natural sweetener and the active component of Rubus suavissimus. The preventive and therapeutic effect of rubusoside on high-fat diet-induced (HFD) serum metabolite changes in golden hamsters...
Wed Mar 11, 2020 02:00
Molecules, Vol. 25, Pages 1275: Attraction and Electrophysiological Response to Identified Rectal Gland Volatiles in Bactrocera frauenfeldi (Schiner) Molecules doi: 10.3390/molecules25061275 Authors: Noushini Perez Park Holgate Mendez Alvarez Jamie Jamie Taylor Bactrocera frauenfeldi (Schiner) (Diptera: Tephritidae) is a polyphagous fruit fly pest species that is endemic to Papua New Guinea and has become established in several Pacific Islands and Australia....
Wed Mar 11, 2020 02:00
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