Clinical and Pathogenic Characteristics of Lower Respiratory Tract Infection Treated at the Vietnam National Children’s Hospital:
Lower respiratory tract infections are commonly caused by viruses and cause significant morbidity and mortality among children. Early identification of the pathological agent causing these infections is essential to avoid unnecessary antibiotic use and improve patient management. Multiplex PCR techniques were recently developed to detect multiple viral pathogens using a single PCR reaction. In this study, we identify viral pathogens in children with respiratory infections. We collected 194 nasopharyngeal aspirates from infants (2–24 months old) with lower respiratory tract infections treated at the Vietnam National Children’s Hospital between November 2014 and June 2015 and assessed the presence of 16 virus types and subtypes by multiplex PCR using the xTAG Respiratory Viral Panel (RVP) assay. Overall, 73.7% of the samples were positive for at least one virus, and 24.2% corresponded to infections with multiple viruses. The most common viruses were respiratory syncytial virus and enterovirus/rhinovirus. These viruses were more frequent among younger patients (2–5 months old) and caused symptoms similar to those of bronchiolitis and pneumonia. The most common clinical manifestation caused by respiratory tract infection was bronchiolitis. Elevated neutrophils levels were associated with adenovirus infection. Our results showed that the xTAG Respiratory Viral Panel (RVP) can effectively detect multiple viruses causing respiratory infections in children and that the nasopharyngeal aspirates are a good sample choice to detect respiratory viruses in children. Applying this approach in the clinical setting would improve patient management and allow early diagnosis, thus avoiding the unnecessary use of antibiotics.
Medicine RSS-Feeds by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com
Πληροφορίες
Τετάρτη 11 Μαρτίου 2020
Clinical and Pathogenic Characteristics of Lower Respiratory Tract Infection
Αναρτήθηκε από
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,
στις
11:20 μ.μ.
Ετικέτες
00302841026182,
00306932607174,
alsfakia@gmail.com,
Anapafseos 5 Agios Nikolaos 72100 Crete Greece,
Medicine by Alexandros G. Sfakianakis,
Telephone consultation 11855 int 1193
Εγγραφή σε:
Σχόλια ανάρτησης (Atom)
Αρχειοθήκη ιστολογίου
-
►
2023
(366)
- ► Φεβρουαρίου (184)
- ► Ιανουαρίου (182)
-
►
2022
(2814)
- ► Δεκεμβρίου (182)
- ► Σεπτεμβρίου (213)
- ► Φεβρουαρίου (264)
- ► Ιανουαρίου (262)
-
►
2021
(3815)
- ► Δεκεμβρίου (229)
- ► Σεπτεμβρίου (276)
- ► Φεβρουαρίου (64)
-
▼
2020
(5754)
- ► Δεκεμβρίου (401)
- ► Σεπτεμβρίου (365)
-
▼
Μαρτίου
(804)
-
▼
Μαρ 11
(157)
- Medicine
- Brain Sciences
- pubmed: sleep
- pubmed: sleep
- AA pubmed: head and neck
- edoc: No conditions. Results ordered -Date De...
- ScienceDirect Publication: Cell Reports
- Intranasal pain in a patient with Behcet’s disease
- Comparison of the effect of Roux‐en‐Y gastric bypa...
- Bilateral Femoral Neuropathy: A Rare Complication ...
- Adjuvant Therapies in Diabetic Retinopathy as an E...
- Comparative study between topically applied irradi...
- Antimicrobial Effect of a Peptide Containing Novel...
- Endovascular Treatment of Venous Bypass Graft Pseu...
- Diabetes, Fetal Demise, and Shoulder Dystocia: The...
- Optimal Decisions and Pricing in Mail Service Syst...
- A Cardiac Pseudoaneurysm as a Thromboembolic Sourc...
- Effect of Intestinal Levodopa-Carbidopa Infusion o...
- Subcutaneously Anchored Sutureless Device for Secu...
- Detection of Moderate Traumatic Brain Injury from ...
- Arsenic Trioxide Treatment during Pregnancy for Ac...
- Application of Optimal Control to Influenza Pneumo...
- Adult Ectopic Cervical Thymic Tissue in relation t...
- Clinical and Pathogenic Characteristics of Lower R...
- Organoids as a Powerful Model for Respiratory Dise...
- One Lung Soldier: A Ventilation Conundrum in a Pos...
- Clinical Examination and Self-Reported Upper Extre...
- Time to Recovery from Severe Acute Malnutrition an...
- Umbilical cord blood donation in pregnant women
- Hair follicle regeneration by injections of epider...
- The Challenges of Managing Ovarian Cancer in the D...
- Increased Vulnerability to Pregnancy and Sexual Vi...
- Research on Multi-Time-Delay Gene Regulation Netwo...
- Long Noncoding RNA Lnc-TLN2-4:1 Suppresses Gastric...
- Radiation-Induced Left Main Coronary Artery Stenos...
- A prospective multicentre REFCOR study of 470 case...
- British Journal of Cancer -
- Latest Results for Aging Clinical and Experime...
- Indian Journal of Anaesthesia :
- Latest Results for European Archives of Oto-Rh...
- A stepwise titration protocol for oral appliance t...
- Effectiveness of sleep surgery versus a mandibular...
- Tissue Engineering Part A - Table of Contents,...
- Coccidioidomycosis in Children and Adolescents: an...
- Viruses
- Nutrien
- Mole
- International Journal of Molecular Sciences,
- Diversity
- Antibioti
- pubmed: frontiers in neurosc...
- Hypopharyngeal Dedifferentiated Liposarcoma in the...
- pubmed: "world neurosurg"[jo...
- Head and Neck
- PeerJ Computer Science
- Oncology
- Cervial vestibular-evoked myogenic potential induc...
- World Neurosurgery
- European Journal of Nuclear Medicine and Mole...
- Hair cortisol analyses in different mammal species...
- Future Oncology
- MiR-324-5p/PTPRD/CEBPD axis promotes papillary thy...
- Nasal Airway Resistance and Latent Lower Airway...
- 1. PLoS One. 2020 Mar 10;15(3):e0229355. doi:...
- HNO
- "Proc Natl Acad Sci U S A"[jour]; +37 new citations
- ANZ Journal of Surgery
- International Journal of Cancer
- Clinical & Experimental Allergy
- Parasite
- bioRxiv Subject Collection: Evolutionary Biol...
- World Journal of Emergency Surgery - Latest A...
- Medicine by Alexandros G. Sfakianakis,Anapafseos 5...
- Use of immunotherapy and surgery for stage IV mela...
- Pathogenic variants in TNRC6B cause a genetic diso...
- Diurnal variation in autonomic regulation among pa...
- Epigenetic Modification of CFTR in Head and Neck C...
- Endoscopic Submucosal Dissection of Gastric Neopla...
- Breast-Specific Gamma Imaging with [99mTc]Tc-Sesta...
- Cerebral and Splanchnic Vein Thrombosis: Advances,...
- Enhanced Inflammation and Nitrosative Stress in th...
- Impact of neutrophil-to-lymphocyte ratio in pat...
- Intra-tympanic administered thiosulfate to prevent...
- Safety and influence of a novel powder form of ...
-
▼
Μαρ 11
(157)
- ► Φεβρουαρίου (754)
- ► Ιανουαρίου (894)
-
►
2019
(146)
- ► Δεκεμβρίου (19)
- ► Σεπτεμβρίου (54)
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου