Metabolites, Vol. 10, Pages 140: Delta-Integration of Single Gene Shapes the Whole Metabolomic Short-Term Response to Ethanol of Recombinant Saccharomyces cerevisiae Strains Metabolites doi: 10.3390/metabo10040140 Authors: Laura Corte Luca Roscini Debora Casagrande Pierantoni Roberto Maria Pellegrino Carla Emiliani Marina Basaglia Lorenzo Favaro Sergio Casella Gianluigi Cardinali In yeast engineering, metabolic burden is often linked to the reprogramming of resources...
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MPs, Vol. 3, Pages 28: Mapping Quantitative Trait Loci onto Chromosome-Scale Pseudomolecules in Flax
MPs, Vol. 3, Pages 28: Mapping Quantitative Trait Loci onto Chromosome-Scale Pseudomolecules in Flax Methods and Protocols doi: 10.3390/mps3020028 Authors: Frank M. You Sylvie Cloutier Quantitative trait loci (QTL) are genomic regions associated with phenotype variation of quantitative traits. To date, a total of 313 QTL for 31 quantitative traits have been reported in 14 studies on flax. Of these, 200 QTL from 12 studies were identified based on genetic maps, the scaffold sequences,...
MPs, Vol. 3, Pages 27: An Optimised Step-by-Step Protocol for Measuring Relative Telomere Length Methods and Protocols doi: 10.3390/mps3020027 Authors: Joglekar Satoor Wong Cheng Ma Hardikar Telomeres represent the nucleotide repeat sequences at the ends of chromosomes and are essential for chromosome stability. They can shorten at each round of DNA replication mainly because of incomplete DNA synthesis of the lagging strand. Reduced relative telomere length is associated...
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Microorganisms, Vol. 8, Pages 521: The Response to Oxidative Stress in Listeria monocytogenes Is Temperature Dependent Microorganisms doi: 10.3390/microorganisms8040521 Authors: Manso Melero Stessl Jaime Wagner Rovira Rodríguez-Lázaro The stress response of 11 strains of Listeria monocytogenes to oxidative stress was studied. The strains included ST1, ST5, ST7, ST6, ST9, ST87, ST199 and ST321 and were isolated from diverse food processing environments (a meat...
Microorganisms, Vol. 8, Pages 522: Draft Genome Sequence of the Urinary Catheter Isolate Enterobacter ludwigii CEB04 with High Biofilm Forming Capacity Microorganisms doi: 10.3390/microorganisms8040522 Authors: Shafeeq Wang Lünsdorf Brauner Römling : Enterobacter ludwigii is a fermentative Gram-negative environmental species and accidental human pathogen that belongs to the Enterobacter cloacae complex with the general characteristics of the genus Enterobacter. The clinical...
Microorganisms, Vol. 8, Pages 520: Germ-Free Swiss Webster Mice on a High-Fat Diet Develop Obesity, Hyperglycemia, and Dyslipidemia Microorganisms doi: 10.3390/microorganisms8040520 Authors: Logan Bobe Miranda Vasquez-Perez Choi Lowry Sharpton Morgun Maier Stevens Shulzhenko Gombart A calorie-dense diet is a well-established risk factor for obesity and metabolic syndrome (MetS), whereas the role of the intestinal microbiota (IMB) in the development...
Microorganisms, Vol. 8, Pages 519: Engineering Improves Enzymatic Synthesis of L-Tryptophan by Tryptophan Synthase from Escherichia coli Microorganisms doi: 10.3390/microorganisms8040519 Authors: Lisheng Xu Fangkai Han Zeng Dong Zhaojun Wei To improve the thermostability of tryptophan synthase, the molecular modification of tryptophan synthase was carried out by rational molecular engineering. First, B-FITTER software was used to analyze the temperature factor (B-factor) of...
Microorganisms, Vol. 8, Pages 518: iTRAQ-based Quantitative Proteomics Analysis Identifies Host Pathways Modulated during Toxoplasma gondii Infection in Swine Microorganisms doi: 10.3390/microorganisms8040518 Authors: He Ma Wang Zhang Li Zhai Elsheikha Zhu Toxoplasma gondii is a leading cause of foodborne illness and consumption of undercooked pig meat is a major risk factor for acquiring toxoplasmosis, which causes a substantial burden on society. Here,...
Microorganisms, Vol. 8, Pages 517: Phenotype, Virulence and Immunogenicity of Edwardsiella piscicida Cyclic AMP Receptor Protein (Crp) Mutants in Catfish Host Microorganisms doi: 10.3390/microorganisms8040517 Authors: Zhou Han Ye Zheng Yan Xie Zhang Curtiss III Zhou Edwardsiella piscicida, a facultative aerobic pathogen belonging to the Enterobacteriaceae family, is the etiological agent of edwardsiellosis that causes significant economic loses in the...
Microorganisms, Vol. 8, Pages 516: Inoculum Strategies and Performances of Malolactic Starter Lactobacillus plantarum M10: Impact on Chemical and Sensorial Characteristics of Fiano Wine Microorganisms doi: 10.3390/microorganisms8040516 Authors: Silvia Jane Lombardi Gianfranco Pannella Massimo Iorizzo Bruno Testa Mariantonietta Succi Patrizio Tremonte Elena Sorrentino Massimo Di Renzo Daniela Strollo Raffaele Coppola Malolactic fermentation (MLF) is a biological...
Microorganisms, Vol. 8, Pages 515: The Cytomegalovirus Protein Kinase pUL97:Host Interactions, Regulatory Mechanisms and Antiviral Drug Targeting Microorganisms doi: 10.3390/microorganisms8040515 Authors: Steingruber Marschall Human cytomegalovirus (HCMV) expresses a variety of viral regulatory proteins that undergo close interaction with host factors including viral-cellular multiprotein complexes. The HCMV protein kinase pUL97 represents a viral cyclin-dependent kinase ortholog...
Microorganisms, Vol. 8, Pages 514: The Porcine Nasal Microbiota with Particular Attention to Livestock-Associated Methicillin-Resistant Staphylococcus aureus in Germany—A Culturomic Approach Microorganisms doi: 10.3390/microorganisms8040514 Authors: Andreas Schlattmann Knut von Lützau Ursula Kaspar Karsten Becker Livestock-associated methicillin-resistant Staphylococcus aureus (LA-MRSA) remains a serious public health threat. Porcine nasal cavities are predominant habitats of...
Microorganisms, Vol. 8, Pages 513: Relationships Between Gut Microbiota, Metabolome, Body Weight, and Glucose Homeostasis of Obese Dogs Fed with Diets Differing in Prebiotic and Protein Content Microorganisms doi: 10.3390/microorganisms8040513 Authors: Apper Privet Taminiau Le Bourgot Svilar Martin Diez Obesity is a major issue in pets and nutritional strategies need to be developed, like promoting greater protein and fiber intake. This study aimed to evaluate...
Microorganisms, Vol. 8, Pages 512: Symbioflor2® Escherichia coli Genotypes Enhance Ileal and Colonic Gene Expression Associated with Mucosal Defense in Gnotobiotic Mice Microorganisms doi: 10.3390/microorganisms8040512 Authors: Unai Escribano-Vazquez Claudia Beimfohr Deborah Bellet Muriel Thomas Kurt Zimmermann Philippe Langella Claire Cherbuy Symbioflor2® is a probiotic product composed of six Escherichia coli genotypes, which has a beneficial effect on irritable...
Microorganisms, Vol. 8, Pages 511: Candida albicans Adaptation on Simulated Human Body Fluids under Different pH Microorganisms doi: 10.3390/microorganisms8040511 Authors: Ana Barbosa Daniela Araújo Eduarda Ribeiro Mariana Henriques Sónia Silva Candida albicans remains the most problematic of all Candida species, causing severe infections. Adaptation to different human body niches, such oral and urinary tracts, has been shown to be essential for survival and critical for...
Microorganisms, Vol. 8, Pages 510: Changes in the Trophic Pathways within the Microbial Food Web in the Global Warming Scenario: An Experimental Study in the Adriatic Sea Microorganisms doi: 10.3390/microorganisms8040510 Authors: Šolić Šantić Šestanović Bojanić Jozić Ordulj Tomaš Kušpilić A recent analysis of the Mediterranean Sea surface temperature showed significant annual warming. Since small picoplankton microorganisms play an important role in all major...
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Molecules, Vol. 25, Pages 1677: A Peptide Nucleic Acid (PNA) Masking the miR-145-5p Binding Site of the 3’UTR of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) mRNA Enhances CFTR Expression in Calu-3 Cells Molecules doi: 10.3390/molecules25071677 Authors: Sultan Rozzi Gasparello Manicardi Corradini Papi Finotti Lampronti Reali Cabrini Gambari Borgatti Peptide nucleic acids (PNAs) have been demonstrated to be very useful tools...
Molecules, Vol. 25, Pages 1676: Toxic, Radical Scavenging, and Antifungal Activity of Rhododendron tomentosum H. Essential Oils Molecules doi: 10.3390/molecules25071676 Authors: Asta Judzentiene Jurga Budiene Jurgita Svediene Rasa Garjonyte The chemical composition of eight (seven shoot and one inflorescence) essential oils (EOs) of Rh. tomentosum H. plants growing in Eastern Lithuania is reported. The plant material was collected during different phases of vegetation (from...
Molecules, Vol. 25, Pages 1674: Hepcidin and Erythroferrone Correlate with Hepatic Iron Transporters in Rats Supplemented with Multispecies Probiotics Molecules doi: 10.3390/molecules25071674 Authors: Katarzyna Skrypnik Paweł Bogdański Magdalena Sobieska Joanna Suliburska The influence of probiotic supplementation on iron metabolism remains poorly investigated. However, a range of studies, especially on Lactobacillus plantarum 299v (Lp229v), have indicated a possible positive...
Molecules, Vol. 25, Pages 1675: Recent Advances in Synthesis of Benzothiazole Compounds Related to Green Chemistry Molecules doi: 10.3390/molecules25071675 Authors: Xiang Gao Jiao Liu Xin Zuo Xinyue Feng Ying Gao Benzothiazoles have played an important role in the field of biochemistry and medicinal chemistry due to their highly pharmaceutical and biological activity. The development of synthetic processes is undoubtedly one of the most significant problems facing researchers....
Molecules, Vol. 25, Pages 1673: Novel Mutant Phospholipase D from Hemiscorpius lepturus Acts as A Highly Immunogen in BALB/c Mice Against the Lethality of Scorpion Venom Molecules doi: 10.3390/molecules25071673 Authors: Abouzar Soleimani Moez Reza H. Sajedi Kamran Pooshang Bagheri Jean-Marc Sabatier Delavar Shahbazzadeh Hemiscorpius lepturus (H. lepturus) which belongs to the Scorpionidae family, is the deadliest scorpion in Iran. It causes pathological manifestations like...
Molecules, Vol. 25, Pages 1672: Novel Anthraquinone Compounds Inhibit Colon Cancer Cell Proliferation via the Reactive Oxygen Species/JNK Pathway Molecules doi: 10.3390/molecules25071672 Authors: Yuying Li Fang Guo Yingying Guan Tinggui Chen Kaiqing Ma Liwei Zhang Zhuanhua Wang Qiang Su Liheng Feng Yaoming Liu Yuzhi Zhou A series of amide anthraquinone derivatives, an important component of some traditional Chinese medicines, were structurally modified and...
Molecules, Vol. 25, Pages 1671: New Phosphine Oxides as High Performance Near- UV Type I Photoinitiators of Radical Polymerization Molecules doi: 10.3390/molecules25071671 Authors: Céline Dietlin Thanh Tam Trinh Stéphane Schweizer Bernadette Graff Fabrice Morlet-Savary Pierre-Antoine Noirot Jacques Lalevée Carbazole structures are of high interest in photopolymerization due to their enhanced light absorption properties in the near-UV or even visible ranges. Therefore,...
Molecules, Vol. 25, Pages 1670: Addition of Orange Peel in Orange Jam: Evaluation of Sensory, Physicochemical, and Nutritional Characteristics Molecules doi: 10.3390/molecules25071670 Authors: Flavia Teixeira Bruna Aparecida dos Santos Graziela Nunes Jaqueline Machado Soares Luane Aparecida do Amaral Gabriel Henrique Oliveira de Souza Juliano Tadeu Vilela de Resende Bruna Menegassi Bruna Paola Murino Rafacho Kélin Schwarz Elisvânia Freitas dos Santos Daiana...
Molecules, Vol. 25, Pages 1668: Synthesis, Structure and In Vitro Anti-Trypanosomal Activity of Non-Toxic Arylpyrrole-Based Chalcone Derivatives Molecules doi: 10.3390/molecules25071668 Authors: Ayanda I. Zulu Ogunyemi O. Oderinlo Cuan Kruger Michelle Isaacs Heinrich C. Hoppe Vincent J. Smith Clinton G. L. Veale Setshaba D. Khanye With an intention of identifying chalcone derivatives exhibiting anti-protozoal activity, a cohort of relatively unexplored arylpyrrole-based...
Molecules, Vol. 25, Pages 1669: An Overview of Effects Induced by Pasteurization and High-Power Ultrasound Treatment on the Quality of Red Grape Juice Molecules doi: 10.3390/molecules25071669 Authors: Alina Margean Mirabela Ioana Lupu Ersilia Alexa Vasile Padureanu Cristina Maria Canja Ileana Cocan Monica Negrea Gavrila Calefariu Mariana-Atena Poiana In juice processing, ultrasound treatment has been tested as a potential alternative to conventional thermal methods...
Molecules, Vol. 25, Pages 1667: A Pilot Study on the Effect of Anti-Thrombopoietin Antibody on Platelet Count in Patients with Type 2 Diabetes Molecules doi: 10.3390/molecules25071667 Authors: Takuya Fukuda Masahide Hamaguchi Takafumi Osaka Yoshitaka Hashimoto Emi Ushigome Mai Asano Masahiro Yamazaki Eriko Fukuda Kei Yamaguchi Koji Ogawa Naoki Goshima Michiaki Fukui Thrombopoietin (THPO) is a circulatory cytokine that plays an important role in platelet...
Molecules, Vol. 25, Pages 1666: Determination of Albumin, Glucose, and Creatinine Employing a Single Sequential Injection Lab-at-Valve with Mono-Segmented Flow System Enabling In-Line Dilution, In-Line Single-Standard Calibration, and In-Line Standard Addition Molecules doi: 10.3390/molecules25071666 Authors: Kanokwan Kiwfo Wasin Wongwilai Tadao Sakai Norio Teshima Kate Grudpan A mono-segmented sequential injection lab-at-valve (SI-LAV) system for the determination of albumin,...
Molecules, Vol. 25, Pages 1664: Quasi-Periodic Dendritic Metasurface for Integral Operation in Visible Light Molecules doi: 10.3390/molecules25071664 Authors: Huan Chen Di An Xiaopeng Zhao A reflective metasurface model composed of silver dendritic units is designed in this study. The integral property of this metasurface, which consists of an upper layer of dendritic structures, a silica spacer, and a bottom silver substrate was demonstrated at visible wavelengths. The simulation...
Molecules, Vol. 25, Pages 1665: Fluorimetric Method for the Determination of Histidine in Random Human Urine Based on Zone Fluidics Molecules doi: 10.3390/molecules25071665 Authors: Antonios Alevridis Apostolia Tsiasioti Constantinos K. Zacharis Paraskevas D. Tzanavaras In the present study, the determination of histidine (HIS) by an on-line flow method based on the concept of zone fluidics is reported. HIS reacts fast with o-phthalaldehyde at a mildly basic medium (pH 7.5)...
Molecules, Vol. 25, Pages 1663: Directing 2D-Coordination Networks: Combined Effects of a Conformationally Flexible 3,2′:6′,3″-Terpyridine and Chain Length Variation in 4′-(4-n-Alkyloxyphenyl) Substituents Molecules doi: 10.3390/molecules25071663 Authors: Dalila Rocco Alessandro Prescimone Edwin C. Constable Catherine E. Housecroft The synthesis and characterization of 4′-(4-n-propoxyphenyl)-3,2′:6′,3″-terpyridine is described. Five 2D-coordination...
Molecules, Vol. 25, Pages 1662: Azides and Porphyrinoids: Synthetic Approaches and Applications. Part 1—Azides, Porphyrins and Corroles Molecules doi: 10.3390/molecules25071662 Authors: Ana R. L. Araújo Augusto C. Tomé Carla I. M. Santos Maria A. F. Faustino Maria G. P. M. S. Neves Mário M. Q. Simões Nuno M. M. Moura Sultan T. Abu-Orabi José A. S. Cavaleiro Azides and porphyrinoids (such as porphyrin and corrole macrocycles) can give rise to new derivatives with...
Molecules, Vol. 25, Pages 1660: Optimization of the Production Factors of Boards Obtained from Arundo donax L. Fibers Without Added Adhesives Molecules doi: 10.3390/molecules25071660 Authors: Ramos Ferrando Farriol Salvadó The main objective of this work was to further analyze the optimization of the production factors of Arundo donax L. fiberboards obtained without adhesives. The production of boards derived from Arundo donax L. without added adhesives and with high mechanical...
Molecules, Vol. 25, Pages 1661: Theoretical and Computational Insight into Solvent and Specific Ion Effects for Polyelectrolytes: The Importance of Local Molecular Interactions Molecules doi: 10.3390/molecules25071661 Authors: Jens Smiatek Polyelectrolytes in solution show a broad plethora of interesting effects. In this short review article, we focus on recent theoretical and computational findings regarding specific ion and solvent effects and their impact on the polyelectrolyte behavior....
Molecules, Vol. 25, Pages 1658: Exercise Affects Blood Glucose Levels and Tissue Chromium Distribution in High-Fat Diet-Fed C57BL6 Mice Molecules doi: 10.3390/molecules25071658 Authors: Geng-Ruei Chang Po-Hsun Hou Wen-Kai Chen Chien-Teng Lin Hsiao-Pei Tsai Frank Chiahung Mao Obesity is commonly associated with hyperglycemia and type 2 diabetes and negatively affects chromium accumulation in tissues. Exercise prevents and controls obesity and type 2 diabetes. However, little...
Molecules, Vol. 25, Pages 1656: Mono-, Di- and Tetra-iron Complexes with Selenium or Sulphur Functionalized Vinyliminium Ligands: Synthesis, Structural Characterization and Antiproliferative Activity Molecules doi: 10.3390/molecules25071656 Authors: Gabriele Agonigi Lucinda K. Batchelor Eleonora Ferretti Silvia Schoch Marco Bortoluzzi Simona Braccini Federica Chiellini Lorenzo Biancalana Stefano Zacchini Guido Pampaloni Biprajit Sarkar Paul J. Dyson Fabio...
Molecules, Vol. 25, Pages 1657: Nuphar lutea Extracts Exhibit Anti-Viral Activity against the Measles Virus Molecules doi: 10.3390/molecules25071657 Authors: Hila Winer Janet Ozer Yonat Shemer Irit Reichenstein Brit Eilam-Frenkel Daniel Benharroch Avi Golan-Goldhirsh Jacob Gopas Different parts of Nuphar lutea L. (yellow water lily) have been used to treat several inflammatory and pathogen-related diseases. It has shown that Nuphar lutea extracts (NUP) are active...
Molecules, Vol. 25, Pages 1655: A Tryptophan Metabolite, 8-Hydroxyquinaldic Acid, Exerts Antiproliferative and Anti-Migratory Effects on Colorectal Cancer Cells Molecules doi: 10.3390/molecules25071655 Authors: Katarzyna Walczak Ewa Langner Karolina Szalast Anna Makuch-Kocka Piotr Pożarowski Tomasz Plech 8-Hydroxyquinaldic acid, the end-metabolite of tryptophan, is well-known metal chelator; however, its role in humans, especially in cancer promotion and progression, has...
Molecules, Vol. 25, Pages 1653: Effects of Bilberry Supplementation on Metabolic and Cardiovascular Disease Risk Molecules doi: 10.3390/molecules25071653 Authors: Chan Tomlinson Metabolic syndrome is a cluster of interrelated conditions that is associated with an increased risk of cardiovascular disease (CVD) and type 2 diabetes mellitus (T2DM). Oxidative stress may impair normal physiological functions, leading to various illnesses. T2DM is considered to be associated with increased...
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