Social Sciences, Vol. 9, Pages 41: Michael Walzer’s Humanitarian Intervention Theory Applied to Multisided Conflicts: A Discussion of Intervention and Self-Determination in the Syrian Civil War Social Sciences doi: 10.3390/socsci9040041 Authors: Miguel Paradela-López Alexandra Jima-González Humanitarian interventions have often been employed to promote the intervener’s political and economic interests. Given the issues around intervention’s morality, this article...
Social Sciences, Vol. 9, Pages 40: The Shift from Consumers to Prosumers: Susceptibility of Young Adults to Radicalization Social Sciences doi: 10.3390/socsci9040040 Authors: Rahma Sugihartati Bagong Suyanto Mun’im Sirry This article examines the radicalization of young adults in relation to internet access and the social media content produced and managed by radical groups in Indonesia. Some of the research problems that become the major concern of this article were how young...
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Sports, Vol. 8, Pages 45: A Cluster Set Protocol in the Half Squat Exercise Reduces Mechanical Fatigue and Lactate Concentrations in Comparison with A Traditional Set Configuration Sports doi: 10.3390/sports8040045 Authors: Varela-Olalla Romero-Caballero Del Campo-Vecino Balsalobre-Fernández Splitting sets into clusters has been shown to maintain performance during resistance training. This study compared the acute fatigue produced by a traditional (TSC) versus a cluster...
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Stats, Vol. 3, Pages 84-93: The Prediction of Batting Averages in Major League Baseball Stats doi: 10.3390/stats3020008 Authors: Sarah R. Bailey Jason Loeppky Tim B. Swartz The prediction of yearly batting averages in Major League Baseball is a notoriously difficult problem where standard errors using the well-known PECOTA (Player Empirical Comparison and Optimization Test Algorithm) system are roughly 20 points. This paper considers the use of ball-by-ball data provided by the...
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Toxics, Vol. 8, Pages 26: Remediation of Cr(VI)-Contaminated Soil by Nano-Zero-Valent Iron in Combination with Biochar or Humic Acid and the Consequences for Plant Performance Toxics doi: 10.3390/toxics8020026 Authors: Yuhuan Sun Fangyuan Zheng Wenjie Wang Shuwu Zhang Fayuan Wang Nano-scale zero-valent iron (nZVI) is among the most common nanoparticles widely used for the treatment of various environmental contaminants. However, little is known about the combined effects...
Toxics, Vol. 8, Pages 25: Chemical Constituents Involved in E-Cigarette, or Vaping Product Use-Associated Lung Injury (EVALI) Toxics doi: 10.3390/toxics8020025 Authors: Thivanka Muthumalage Michelle R. Friedman Matthew D. McGraw Garry Ginsberg Alan E. Friedman Irfan Rahman The Centers for Disease Control declared e-cigarette, or vaping, product use-associated lung injury (EVALI) a national outbreak due to the high incidence of emergency department admissions and deaths....
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Toxins, Vol. 12, Pages 230: Centipede Venom Peptides Acting on Ion Channels Toxins doi: 10.3390/toxins12040230 Authors: YanYan Chu PeiJu Qiu RiLei Yu Centipedes are among the oldest venomous arthropods that use their venom to subdue the prey. The major components of centipede venom are a variety of low-molecular-weight peptide toxins that have evolved to target voltage-gated ion channels to interfere with the central system of prey and produce pain or paralysis for efficient hunting....
Toxins, Vol. 12, Pages 229: Indoxyl Sulfate, a Uremic Endotheliotoxin Toxins doi: 10.3390/toxins12040229 Authors: Guillaume Lano Stéphane Burtey Marion Sallée Chronic kidney disease (CKD) is associated with a high prevalence of cardiovascular diseases. During CKD, the uremic toxin indoxyl sulfate (IS)—derived from tryptophan metabolism—accumulates. IS is involved in the pathophysiology of cardiovascular complications. IS can be described as an endotheliotoxin:...
Toxins, Vol. 12, Pages 227: Inflammation and Premature Ageing in Chronic Kidney Disease Toxins doi: 10.3390/toxins12040227 Authors: Thomas Ebert Sven-Christian Pawelzik Anna Witasp Samsul Arefin Sam Hobson Karolina Kublickiene Paul G. Shiels Magnus Bäck Peter Stenvinkel Persistent low-grade inflammation and premature ageing are hallmarks of the uremic phenotype and contribute to impaired health status, reduced quality of life, and premature mortality in chronic...
Toxins, Vol. 12, Pages 228: Investigation of In Vitro Endocrine Activities of Microcystis and Planktothrix Cyanobacterial Strains Toxins doi: 10.3390/toxins12040228 Authors: Vittoria Mallia Lada Ivanova Gunnar S. Eriksen Emma Harper Lisa Connolly Silvio Uhlig Cyanobacteria are cosmopolitan photosynthetic prokaryotes that can form dense accumulations in aquatic environments. They are able to produce many bioactive metabolites, some of which are potentially endocrine disrupting...
Toxins, Vol. 12, Pages 225: Conversion of Deoxynivalenol-3-Glucoside to Deoxynivalenol during Chinese Steamed Bread Processing Toxins doi: 10.3390/toxins12040225 Authors: Huijie Zhang Li Wu Weixi Li Yan Zhang Jingmei Li Xuexu Hu Lijuan Sun Wenming Du Bujun Wang We reported the conversion of deoxynivalenol-3-glucoside (D3G) to deoxynivalenol (DON) during Chinese steamed bread (CSB) processing by artificial D3G contamination. Meanwhile, the effects of enzymes in...
Toxins, Vol. 12, Pages 226: Protein-Lipid Interaction of Cytolytic Toxin Cyt2Aa2 on Model Lipid Bilayers of Erythrocyte Cell Membrane Toxins doi: 10.3390/toxins12040226 Authors: Sudarat Tharad Boonhiang Promdonkoy José L. Toca-Herrera Cytolytic toxin (Cyt) is a toxin among Bacillus thuringiensis insecticidal proteins. Cyt toxin directly interacts with membrane lipids for cytolytic action. However, low hemolytic activity is desired to avoid non-specific effects in mammals. In this...
Toxins, Vol. 12, Pages 224: Uremia-Associated Ageing of the Thymus and Adaptive Immune Responses Toxins doi: 10.3390/toxins12040224 Authors: Michiel GH Betjes Progressive loss of renal function is associated with a series of changes of the adaptive immune system which collectively constitute premature immunological ageing. This phenomenon contributes significantly to the mortality and morbidity of end-stage renal disease (ESRD) patients. In this review, the effect of ESRD on the T cell...
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TropicalMed, Vol. 5, Pages 55: Innovative Distance Learning Tool for Morphological Identification of Chigger Mites (Actinotrichida) as Vectors of Scrub Typhus: A Pilot Study Tropical Medicine and Infectious Disease doi: 10.3390/tropicalmed5020055 Authors: Kumlert Pawestri Linsuwanon Morand Scrub typhus, a disease caused by Orientia tsutsugamushi, affects more than one billion people globally with an average fatality rate of 6%. Humans are accidentally infected through the...
TropicalMed, Vol. 5, Pages 54: Molecular Detection of Rickettsia Spp. and Coxiella Burnetii in Cattle, Water Buffalo, and Rhipicephalus (Boophilus) Microplus Ticks in Luzon Island of the Philippines Tropical Medicine and Infectious Disease doi: 10.3390/tropicalmed5020054 Authors: Remil L. Galay Melbourne R. Talactac Bea V. Ambita-Salem Dawn Maureen M. Chu Lali Marie O. dela Costa Cinnamon Mae A. Salangsang Darwin Kyle B. Caracas Florante H. Generoso Jonathan A. Babelonia...
TropicalMed, Vol. 5, Pages 53: An Active Follow-up Strategy for Serological Suspects of Human African Trypanosomiasis with Negative Parasitology Set up by a Health Zone Team in the Democratic Republic of Congo Tropical Medicine and Infectious Disease doi: 10.3390/tropicalmed5020053 Authors: Matthieu Nkieri Florent Mbo Papy Kavunga Pathou Nganzobo Titus Mafolo Chalet Selego Eric Mwamba Miaka Background: The World Health Organization aims for the elimination of Human...
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Urban Science, Vol. 4, Pages 15: Cooperation, Proximity, and Social Innovation: Three Ingredients for Industrial Medium-Sized Towns’ Renewal? Urban Science doi: 10.3390/urbansci4020015 Authors: Marjolaine Gros-Balthazard Magali Talandier Over several decades, medium-sized industrial towns have suffered from a combination of economic and political processes: Deindustrialization, metropolization, and withdrawal of public services. After two decades in which they have been somewhat neglected...
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Vaccines, Vol. 8, Pages 165: Utility of Healthcare System-Based Interventions in Improving the Uptake of Influenza Vaccination in Healthcare Workers at Long-Term Care Facilities: A Systematic Review Vaccines doi: 10.3390/vaccines8020165 Authors: Bechini Lorini Zanobini Mandò Tacconi Boccalini Grazzini Bonanni Bonaccorsi Healthcare workers (HCWs) in long-term care facilities (LTCFs) can represent a source of influenza infection for the elderly. While flu vaccination...
Vaccines, Vol. 8, Pages 164: New Insights on the Emerging Genomic Landscape of CXCR4 in Cancer: A Lesson from WHIM Vaccines doi: 10.3390/vaccines8020164 Authors: Stefania Scala Crescenzo D’Alterio Samantha Milanesi Alessandra Castagna Roberta Carriero Floriana Maria Farina Massimo Locati Elena Monica Borroni Deciphering the molecular alterations leading to disease initiation and progression is currently crucial to identify the most relevant targets for precision...
Vaccines, Vol. 8, Pages 163: Immune Responses and Protective Efficacy of a Formalin-Killed Francisella Noatunensis Subsp. Orientalis Vaccine Evaluated through Intraperitoneal and Immersion Challenge Methods in Oreochromis Niloticus Vaccines doi: 10.3390/vaccines8020163 Authors: Theeraporn Pulpipat Shun Maekawa Pei-Chi Wang Shih-Chu Chen Francisella noatunensis subsp. orientalis (Fno), an intracellular bacterium, causes systemic granulomatous diseases, resulting in high mortality...
Vaccines, Vol. 8, Pages 162: Vaccination with Schistosoma mansoni Cholinesterases Reduces the Parasite Burden and Egg Viability in a Mouse Model of Schistosomiasis Vaccines doi: 10.3390/vaccines8020162 Authors: Bemnet A. Tedla Darren Pickering Luke Becker Alex Loukas Mark S. Pearson Schistosomiasis is a neglected tropical disease caused by parasitic blood flukes of the genus Schistosoma, which kills 300,000 people every year in developing countries, and there is no vaccine....
Vaccines, Vol. 8, Pages 161: Using Next Generation Sequencing to Study the Genetic Diversity of Candidate Live Attenuated Zika Vaccines Vaccines doi: 10.3390/vaccines8020161 Authors: Natalie D. Collins Chao Shan Bruno T.D. Nunes Steven G. Widen Pei-Yong Shi Alan D.T. Barrett Vanessa V. Sarathy Zika virus (ZIKV) is a mosquito-transmitted positive-sense RNA virus in the family Flaviviridae. Candidate live-attenuated vaccine (LAV) viruses with engineered deletions in the...
Vaccines, Vol. 8, Pages 160: GMMA and Glycoconjugate Approaches Compared in Mice for the Development of a Vaccine against Shigella flexneri Serotype 6 Vaccines doi: 10.3390/vaccines8020160 Authors: Maria Michelina Raso Gianmarco Gasperini Renzo Alfini Fabiola Schiavo Maria Grazia Aruta Martina Carducci Maria Concetta Forgione Silvia Martini Paola Cescutti Francesca Necchi Francesca Micoli Shigella infections are one of the top causes of diarrhea throughout...
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Veterinary Sciences, Vol. 7, Pages 38: Impact of Nutritional Supplementation on Canine Dermatological Disorders Veterinary Sciences doi: 10.3390/vetsci7020038 Authors: Andrea Marchegiani Alessandro Fruganti Andrea Spaterna Elena Dalle Vedove Benedetta Bachetti Marcella Massimini Francesco Di Pierro Alessandra Gavazza Matteo Cerquetella Nutritional supplements, also known as complementary feeds, are products administered with the aim of furnishing health benefits,...
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Viruses, Vol. 12, Pages 402: Role of Porcine Aminopeptidase N and Sialic Acids in Porcine Coronavirus Infections in Primary Porcine Enterocytes Viruses doi: 10.3390/v12040402 Authors: Cui Theuns Xie Van den Broeck Nauwynck Porcine epidemic diarrhea virus (PEDV) and transmissible gastroenteritis virus (TGEV) have been reported to use aminopeptidase N (APN) as a cellular receptor. Recently, the role of APN as a receptor for PEDV has been questioned. In our study, the role...
Viruses, Vol. 12, Pages 401: Die Another Way: Interplay between Influenza A Virus, Inflammation and Cell Death Viruses doi: 10.3390/v12040401 Authors: Laghlali Lawlor Tate : Influenza A virus (IAV) is a major concern to human health due to the ongoing global threat of a pandemic. Inflammatory and cell death signalling pathways play important roles in host defence against IAV infection. However, severe IAV infections in humans are characterised by excessive inflammation and tissue...
Viruses, Vol. 12, Pages 400: Novel Toscana Virus Reverse Genetics System Establishes NSs as an Antagonist of Type I Interferon Responses Viruses doi: 10.3390/v12040400 Authors: Franziska Woelfl Psylvia Léger Nadia Oreshkova Felix Pahmeier Stefan Windhaber Jana Koch Megan Stanifer Gleyder Roman Sosa Zina M. Uckeley Felix A. Rey Steeve Boulant Jeroen Kortekaas Paul J. Wichgers Schreur Pierre-Yves Lozach The sand fly-borne Toscana virus (TOSV) is the...
Viruses, Vol. 12, Pages 399: Virus-Induced Cytoplasmic Aggregates and Inclusions are Critical Cellular Regulatory and Antiviral Factors Viruses doi: 10.3390/v12040399 Authors: Oluwatayo Israel Olasunkanmi Sijia Chen James Mageto Zhaohua Zhong RNA granules, aggresomes, and autophagy are key players in the immune response to viral infections. They provide countermeasures that regulate translation and proteostasis in order to rewire cell signaling, prevent viral interference, and...
Viruses, Vol. 12, Pages 398: A Novel Divergent Geminivirus Identified in Asymptomatic New World Cactaceae Plants Viruses doi: 10.3390/v12040398 Authors: Rafaela S. Fontenele Andrew M. Salywon Lucas C. Majure Ilaria N. Cobb Amulya Bhaskara Jesús A. Avalos-Calleros Gerardo R. Argüello-Astorga Kara Schmidlin Anthony Khalifeh Kendal Smith Joshua Schreck Michael C. Lund Matias Köhler Martin F. Wojciechowski Wendy C. Hodgson Raul Puente-Martinez Koenraad...
Viruses, Vol. 12, Pages 396: Middle East Respiratory Syndrome Coronavirus (MERS-CoV) Seropositive Camel Handlers in Kenya Viruses doi: 10.3390/v12040396 Authors: Alice N. Kiyong’a Elizabeth A. J. Cook Nisreen M. A. Okba Velma Kivali Chantal Reusken Bart L. Haagmans Eric M. Fèvre Middle East respiratory syndrome (MERS) is a respiratory disease caused by a zoonotic coronavirus (MERS-CoV). Camel handlers, including slaughterhouse workers and herders, are at risk of acquiring...
Viruses, Vol. 12, Pages 397: High Transmission Potential of West Nile Virus Lineage 1 for Cx. pipiens s.l. of Iran Viruses doi: 10.3390/v12040397 Authors: Bakhshi Mousson Vazeille Zakeri Raz de Lamballerie Dinparast-Djadid Failloux : Vector competence is an important parameter in evaluating whether a species plays a role in transmission of an arbovirus. Although the protocols are similar, interpretation of results is unique given the specific interactions...
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Water, Vol. 12, Pages 1036: Dynamics of Biocorrosion in Copper Pipes under Actual Drinking Water Conditions Water doi: 10.3390/w12041036 Authors: Galarce Fischer Díez Vargas Pizarro Deficient disinfection systems enable bacteria to form in drinking water; these can invade plumbing systems even if the pipes are composed of antibacterial materials such as copper. Severe copper corrosion by microorganisms and their subsequent release into the water system are evidenced...
Water, Vol. 12, Pages 1035: Long-Term Spatiotemporal Variation and Environmental Driving Forces Analyses of Algal Blooms in Taihu Lake Based on Multi-Source Satellite and Land Observations Water doi: 10.3390/w12041035 Authors: Zhang Hu Ma Zhang The algal blooms caused by the eutrophication of lakes is a major environmental problem. In this study, we took China’s Taihu Lake as the research area, using multi-source satellite imagery data to monitor the information...
Water, Vol. 12, Pages 1034: An MPC-Enabled SWMM Implementation of the Astlingen RTC Benchmarking Network Water doi: 10.3390/w12041034 Authors: Congcong Sun Jan Lorenz Svensen Morten Borup Vicenç Puig Gabriela Cembrano Luca Vezzaro The advanced control of urban drainage systems (UDS) has great potential in reducing pollution to the receiving waters by optimizing the operations of UDS infrastructural elements. Existing controls vary in complexity, including local and global...
Water, Vol. 12, Pages 1033: Investigating the Impacts of Water Conservation on Water Quality in Distribution Networks Using an Advection-Dispersion Transport Model Water doi: 10.3390/w12041033 Authors: Ahmed A. Abokifa Lu Xing Lina Sela With the increasing adoption of demand management strategies and water conservation practices, domestic water consumption is projected to decline in the future. The subsequent consumer-side demand reductions are expected to result in increased residence...
Water, Vol. 12, Pages 1030: Assessing Inhomogeneities in Extreme Annual Rainfall Data Series by Multifractal Approach Water doi: 10.3390/w12041030 Authors: Amanda P. García-Marín Javier Estévez Renato Morbidelli Carla Saltalippi José Luis Ayuso-Muñoz Alessia Flammini Testing the homogeneity in extreme rainfall data series is an important step to be performed before applying the frequency analysis method to obtain quantile values. In this work, six homogeneity tests were...
Water, Vol. 12, Pages 1032: A Two-Dimensional Depth-Averaged Sediment Transport Mobile-Bed Model with Polygonal Meshes Water doi: 10.3390/w12041032 Authors: Lai A polygonal-mesh based numerical method is developed to simulate sediment transport in mobile-bed streams with free surfaces. The flow and sediment transport governing equations are depth-averaged and solved in the two-dimensional (2D) horizontal space. The flow and sediment transport are further coupled to the stream bed changes...
Water, Vol. 12, Pages 1031: Concentrations and Loads of Dissolved and Particulate Organic Carbon in Urban Stormwater Runoff Water doi: 10.3390/w12041031 Authors: Stefan Kalev Gurpal S. Toor Urban landscapes are significant contributors of organic carbon (OC) in receiving waters, where elevated levels of OC limit the light availability, increase the transport of pollutants, and result in high costs of potable water treatment. Our objective in this study was to investigate the concentrations,...
Water, Vol. 12, Pages 1029: Climate Change Impact on Surface Water and Groundwater Recharge in Northern Thailand Water doi: 10.3390/w12041029 Authors: Chanchai Petpongpan Chaiwat Ekkawatpanit Duangrudee Kositgittiwong Climate change is progressing and is now one of the most important global challenges for humanities. Water resources management is one of the key challenges to reduce disaster risk. In Northern Thailand, flood and drought have always occurred because of the climate...
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