An analysis of the media consumption habits of people in the US shows that fake news makes up a tiny fraction of what they watch or read every day
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The latest coronavirus news updated every day including coronavirus cases, the latest news, features and interviews from New Scientist and essential information about the covid-19 pandemic
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Add some science to your lockdown living routine, as we make more than 50 incredible talks from our flagship science festival New Scientist Live available for free on YouTube over the coming weeks.
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Cases of covid-19 have been slow to appear in developing economies, but now they are ramping up. Slums and refugee camps could be particularly vulnerable
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Despite data pouring in from many countries, estimates of how many of those infected with covid-19 die still vary widely
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From Chernobyl to Watchmen, this is the best sci-fi on Netflix, Amazon Prime Video and BBC iPlayer at the moment
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Some black holes are way bigger than we can explain, and they may have come from supermassive stars that formed by devouring the other stars around them
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We can't lose sight of the climate emergency when dealing with the covid-19 pandemic, say Christiana Figueres and Tom Rivett-Carnac
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Abstract Purpose Hypertension is a common finding in patients with obstructive sleep apnea (OSA), but it has remained unclear whether or not the amount of disturbed breathing and characteristics of individual respiratory events differ between hypertensive and normotensive patients with severe OSA. Methods Full polysomnographic recordings of 323 men and 89...
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Related ArticlesAn extrathyroid CASTLE tumor in the left neck. Oral Oncol. 2020 Mar 31;:104656 Authors: Jiang L, Zheng WH, Xi Y, Chen C PMID: 32245700 [PubMed - as supplied by publisher]
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Related ArticlesElective neck dissection versus observation for early-stage oral squamous cell carcinoma: Systematic review and meta-analysis. Oral Oncol. 2020 Mar 31;105:104661 Authors: Oh LJ, Phan K, Kim SW, Low TH, Gupta R, Clark JR Abstract INTRODUCTION: Oral squamous cell carcinoma (OSCC) is the seventh most common cancer globally, and has been identified as a growing health concern. This study aims to evaluate the current literature comparing elective...
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Related ArticlesEpithelial stem cell marker LGR6 expression identifies a low-risk subgroup in human papillomavirus positive oropharyngeal squamous cell carcinoma. Oral Oncol. 2020 Mar 31;105:104657 Authors: Jank BJ, Kadletz L, Dunkler D, Haas M, Schnoell J, Kenner L, Heiduschka G Abstract OBJECTIVES: R-Spondins (RSPOs) and leucine-rich repeat-containing G-protein coupled receptors (LGRs) play a critical role in embryonic and cancer development through...
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Related ArticlesScapular tip-thoracodorsal artery perforator free flap for total/subtotal glossectomy defects: Case series and conformance study. Oral Oncol. 2020 Mar 30;105:104660 Authors: Ferrari M, Sahovaler A, Chan HHL, Nicolai P, Irish JC, Gilbert RW Abstract BACKGROUND: Reconstruction of the tongue and floor of mouth after total/subtotal glossectomy poses a major challenge for reconstructive surgeons. Speech and deglutition after total glossectomy...
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Abstract The temporal expression pattern of the circadian clock genes are known to be altered/attenuated with advance in age. Withania somnifera (WS) essentially consists of numerous active constituents including withanolides is known to have antioxidant, anti-inflammatory and adaptogenic properties. We have earlier demonstrated therapeutic effects of hydro-alcoholic leaf extract of WS on the age-induced alterations in the levels and daily rhythms of various clock genes such as...
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Abstract Accumulation of senescent cells in vascular endothelium is known to contribute to vascular aging and increases the risk of developing cardiovascular diseases. The involvement of classical pathways such as p53/p21 and p16/pRB in cellular senescence are well described but there are emerging evidence supporting the increasingly important role of mammalian target of rapamycin (MTOR) as driver of cellular senescence via these pathways or other effector molecules. MicroRNAs...
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Related ArticlesEstablishment of an induced pluripotent stem cell line from a patient with CHARGE syndrome carrying a CHD7 (p.L1151Gfs*17) mutation. Stem Cell Res. 2020 Mar 20;45:101774 Authors: He S, Hu J, Zheng Z, Wang J, Chen J, Zhang C, Li L, Wang J, Chen Z, Shi H, Wang J Abstract CHARGE syndrome is a rare disease caused by a genetic disorder. The clinical features of this syndrome include coloboma of the eye, heart anomaly, choanal atresia,...
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Related ArticlesParathyroid cancer: An update. Cancer Treat Rev. 2020 Mar 19;86:102012 Authors: Rodrigo JP, Hernandez-Prera JC, Randolph GW, Zafereo ME, Hartl DM, Silver CE, Suárez C, Owen RP, Bradford CR, Mäkitie AA, Shaha AR, Bishop JA, Rinaldo A, Ferlito A Abstract Parathyroid cancer (PC) is a rare malignant tumor which comprises 0.5-5% of patients with primary hyperparathyroidism (PHPT). Most of these cancers are sporadic, although it may also...
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Related ArticlesSurgical resection of macrocystic lymphatic malformations of the head and neck: Short and long-term outcomes. Int J Pediatr Otorhinolaryngol. 2020 Mar 20;134:110013 Authors: Bonilla-Velez J, Moore BP, Cleves MA, Buckmiller L, Richter GT Abstract BACKGROUND: Controversy exists on management of lymphatic malformations, with schools of thought advocating for observation, surgery or sclerotherapy. This study sought to examine outcomes...
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Related ArticlesThe impact of Coronavirus (COVID-19) on head and neck cancer patients' care. Radiother Oncol. 2020 Mar 24;147:84-85 Authors: De Felice F, Polimeni A, Valentini V PMID: 32247204 [PubMed - as supplied by publisher]
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Related ArticlesEAT-10 Scores and Fiberoptic Endoscopic Evaluation of Swallowing in Head and Neck Cancer Patients. Laryngoscope. 2020 Apr 04;: Authors: Florie M, Pilz W, Kremer B, Verhees F, Waltman G, Winkens B, Winter N, Baijens L Abstract OBJECTIVE: The purpose of this study was to determine the relationship between patient-reported symptoms of oropharyngeal dysphagia (OD) using the Eating Assessment Tool (EAT)-10 and the swallowing function using...
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Related ArticlesEvaluating Common Cavity Cochlear Deformities Using CT Images and 3D Reconstruction. Laryngoscope. 2020 Apr 04;: Authors: Weiss NM, Langner S, Mlynski R, Roland P, Dhanasingh A Abstract OBJECTIVES: The aim of this study is to compare the common cavity (CC) with the normal anatomy inner ear in order to evaluate whether the cavity is representing both the cochlear and the vestibular parts of the inner ear and to revisit CC deformity...
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Related ArticlesValidation of cone beam computed tomography-based classification method for individual assessment of mid-palatal suture with respect to clinical application among Indian children. Indian J Dent Res. 2020 Jan-Feb;31(1):85-90 Authors: Chanchala HP, Nandlal B, Murthy N, Shanbhog R Abstract Aim: : The aim of this study is to validate the Fernanda Angelieri classification method for the individual assessment of mid-palatal suture among...
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Related ArticlesBiological tumor markers associated with local control after primary radiotherapy in laryngeal cancer: a systematic review. Clin Otolaryngol. 2020 Apr 04;: Authors: Noordhuis MG, Kop EA, van B, der Vegt, Langendijk JA, van BFAM, der Laan, Schuuring E, de Bock GH Abstract BACKGROUND: The choice of treatment in laryngeal cancer is mainly based on tumor stage, post-treatment morbidity and quality of life. Biological tumor markers might...
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Related ArticlesEndogenous α1-antitrypsin levels in the perilymphatic fluid correlates with severity of hearing loss. Clin Otolaryngol. 2020 Apr 04;: Authors: El-Saied S, Schmitt H, Durisin M, Joshua BZ, Abu Tailakh M, Prenzler N, Lenarz T, Kaplan DM, Lewis EC, Warnecke A Abstract OBJECTIVES: To determine the levels of endogenous α1-antitrypsin in the perilymph of patients undergoing cochlear implant (CI), and its reverse association with the severity...
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Related ArticlesSubmandibular gland excision: from external surgery to robotic intraoral and extraoral approaches. Oral Dis. 2020 Apr 04;: Authors: Cammaroto G, Vicini C, Montevecchi F, Bonsembiante A, Meccariello G, Bresciani L, Pelucchi S, Capaccio P Abstract Submandibular gland excision is generally performed through a trans-cervical approach, a safe procedure that, however, carries few neurological, functional and aesthethic drawbacks. Intraoral...
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Related ArticlesLin28 reprograms inner ear glia to a neuronal fate. Stem Cells. 2020 Apr 03;: Authors: Kempfle JS, Luu NC, Petrillo M, Al-Asad R, Zhang A, Edge ASB Abstract Sensorineural hearing loss is irreversible and can be caused by loss of auditory neurons. Regeneration of neural cells from endogenous cells may offer a future tool to restore the auditory circuit and to enhance the performance of implantable hearing devices. Neurons and glial...
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Related ArticlesASO Author Reflections: Pattern and Frequency of Lymph Node Metastasis in Scalp Angiosarcoma. Ann Surg Oncol. 2020 Apr 03;: Authors: Lim SY, Jeong HS PMID: 32246308 [PubMed - as supplied by publisher]
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Related ArticlesDay-case thyroid lobectomy parameters at a tertiary referral head and neck centre: a sensitivity and cost analysis. Eur Arch Otorhinolaryngol. 2020 Apr 03;: Authors: Sheikh Z, Irune E Abstract PURPOSE: Day-case thyroid surgery has been endorsed by the American Thyroid Association and the British Association of Day Surgery. Despite the many benefits of day surgery, day-case thyroid surgery is not widely practiced. We describe the use...
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Related ArticlesHigh dose ibuprofen as a monotherapy on an around-the-clock basis fails to control pain in children undergoing tonsil surgery: a prospective observational cohort study. Eur Arch Otorhinolaryngol. 2020 Apr 03;: Authors: Gude P, Gustedt F, Bellgardt M, Vogelsang H, Herzog-Niescery J, Dazert S, Weber TP, Volkenstein S Abstract PURPOSE: The optimal pain management concept in children after tonsil surgery is controversial. Ibuprofen on...
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Related ArticlesVascular Supply of the Human Spiral Ganglion: Novel Three-Dimensional Analysis Using Synchrotron Phase-Contrast Imaging and Histology. Sci Rep. 2020 Apr 03;10(1):5877 Authors: Mei X, Glueckert R, Schrott-Fischer A, Li H, Ladak HM, Agrawal SK, Rask-Andersen H Abstract Human spiral ganglion (HSG) cell bodies located in the bony cochlea depend on a rich vascular supply to maintain excitability. These neurons are targeted by cochlear...
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Related ArticlesSafety and feasibility of PARP1/2 imaging with 18F-PARPi in patients with head and neck cancer. Clin Cancer Res. 2020 Apr 03;: Authors: Schöder HM, Demétrio De Souza França P, Nakajima R, Burnazi EM, Roberts S, Brand C, Grkovski M, Mauguen A, Dunphy MP, Ghossein R, Lyashchenko SK, Lewis JS, O'Donoghue JA, Ganly I, Patel SG, Lee NY, Reiner T Abstract PURPOSE: We performed a first-in-human clinical trial. The aim of this study was to...
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Related Articles[Epidermolysis bullosa acquisita with Brunsting-Perry type pemphigoid: Diagnostic and therapeutic difficulties]. Ann Dermatol Venereol. 2020 Mar 31;: Authors: Henry J, Bursztejn AC, Bonhomme A, Cuny JF, Mitcov M, Blanchard-Laumonnier E, Schmutz JL Abstract BACKGROUND: Epidermolysis bullosa acquisita (EBA) is a rare auto-immune blistering disease. We report a case of Brunsting-Perry pemphigoid diagnosed by immunoelectron microscopy...
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Related ArticlesThe development of auditory performance and speech perception in CI children after long-period follow up. Am J Otolaryngol. 2020 Mar 19;:102466 Authors: Guo Q, Lyu J, Kong Y, Xu T, Dong R, Qi B, Wang S, Chen X Abstract PURPOSE: The main purpose of the current study was to assess the development of auditory and speech perception and the effects of the age at implantation in CI children after long-period follow up. MATERIALS...
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Related ArticlesQuality of life after total laryngectomy: impact of different vocal rehabilitation methods in a middle income country. Health Qual Life Outcomes. 2020 Apr 03;18(1):92 Authors: Souza FGR, Santos IC, Bergmann A, Thuler LCS, Freitas AS, Freitas EQ, Dias FL Abstract INTRODUCTION: The impact of advanced laryngeal cancer and its extensive surgical treatments cause significant morbidity for these patients. Total laryngectomy impacts essential...
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Related ArticlesEffect of Botulinum Toxin A on Scar Healing after Thyroidectomy: A Prospective Double-blind Randomized Controlled Trial. J Clin Med. 2020 Mar 21;9(3): Authors: Bae DS, Koo DH, Kim JE, Cho JM, Park JO Abstract The persistence of neck scarring is a common concern among patients undergoing thyroidectomy. Botulinum toxin A (BTA (Botox)) has been shown to suppress scar enlargement at the incision site. The objective of this study was to...
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Related ArticlesThe Effects of Short-Term and Long-term Hearing Changes on Music Exposure: A Systematic Review and Meta-Analysis. Int J Environ Res Public Health. 2020 Mar 21;17(6): Authors: You S, Kong TH, Han W Abstract The present study explores the scientific evidence on whether music exposure temporarily or permanently affects hearing sensitivity in young adults. Six electronic databases were searched using related keywords for the four categories...
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Related ArticlesThe Role of Nicotinamide in Cancer Chemoprevention and Therapy. Biomolecules. 2020 Mar 20;10(3): Authors: Nikas IP, Paschou SA, Ryu HS Abstract Nicotinamide (NAM) is a water-soluble form of Vitamin B3 (niacin) and a precursor of nicotinamide-adenine dinucleotide (NAD+) which regulates cellular energy metabolism. Except for its role in the production of adenosine triphosphate (ATP), NAD+ acts as a substrate for several enzymes including...
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Related ArticlesDetermining Malnutrition Assessment Criteria to Predict One-Year Mortality for Locally Advanced Head and Neck Cancer Patients Undergoing Concurrent Chemoradiotherapy. Nutrients. 2020 Mar 20;12(3): Authors: Ling HH, Yeh KY, Ng SH, Wang CH, Lai CH, Wu TH, Chang PH, Chou WC, Chen FP, Lin YC Abstract Study on the impact of pretreatment malnutrition on treatment outcomes in locally advanced head and neck cancer (LAHNC) patients is still...
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