Antibiotics, Vol. 9, Pages 161: Clonal Structure, Virulence Factor-encoding Genes and Antibiotic Resistance of Escherichia coli, Causing Urinary Tract Infections and Other Extraintestinal Infections in Humans in Spain and France during 2016 Antibiotics doi: 10.3390/antibiotics9040161 Authors: Saskia-Camille Flament-Simon Marie-Hélène Nicolas-Chanoine Vanesa García Marion Duprilot Noémie Mayer María Pilar Alonso Isidro García-Meniño Jesús E. Blanco Miguel Blanco Jorge...
Sat Apr 04, 2020 03:00
Antibiotics, Vol. 9, Pages 160: Benzamide Derivatives Targeting the Cell Division Protein FtsZ: Modifications of the Linker and the Benzodioxane Scaffold and Their Effects on Antimicrobial Activity Antibiotics doi: 10.3390/antibiotics9040160 Authors: Valentina Straniero Lorenzo Suigo Andrea Casiraghi Victor Sebastián-Pérez Martina Hrast Carlo Zanotto Irena Zdovc Carlo De Giuli Morghen Antonia Radaelli Ermanno Valoti Filamentous temperature-sensitive Z (FtsZ)...
Sat Apr 04, 2020 03:00
Antibiotics, Vol. 9, Pages 159: Innate Antimicrobial Defense of Skin and Oral Mucosa Antibiotics doi: 10.3390/antibiotics9040159 Authors: Philip W. Wertz Sarah de Szalay This special issue intends to review and update our understanding of the antimicrobial defense mechanisms of the skin and oral cavity. These two environments are quite different in terms of water, pH, and nutrient availability, but have some common antimicrobial factors. The skin surface supports the growth of a limited...
Fri Apr 03, 2020 03:00
Antioxidants, Vol. 9, Pages 301: Plasma Non-Enzymatic Antioxidant Capacity (NEAC) in Relation to Dietary NEAC, Nutrient Antioxidants and Inflammation-Related Biomarkers Antioxidants doi: 10.3390/antiox9040301 Authors: Carrión-García Guerra-Hernández García-Villanova Serafini Sánchez Amiano Molina-Montes (1) Background: Little is known about the interlinkages between dietary and plasma non-enzymatic antioxidant capacity (D-NEAC and P-NEAC, respectively) and the...
Sun Apr 05, 2020 03:00
Antioxidants, Vol. 9, Pages 299: Study of Polyphenol Content and Antioxidant Properties of Various Mix of Chocolate MILK Masses with Different Protein Content Antioxidants doi: 10.3390/antiox9040299 Authors: Bogumiła Urbańska Tomasz Szafrański Hanna Kowalska Jolanta Kowalska The aim of the study was to analyze the antioxidant character of conched chocolate milk masses, taking into account different protein content in milk. For the study, cocoa liquor obtained from roasted and...
Fri Apr 03, 2020 03:00
Antioxidants, Vol. 9, Pages 300: Variation in Macronutrient Content, Phytochemical Constitution and In Vitro Antioxidant Capacity of Green and Red Butterhead Lettuce Dictated by Different Developmental Stages of Harvest Maturity Antioxidants doi: 10.3390/antiox9040300 Authors: Christophe El-Nakhel Antonio Pannico Giulia Graziani Marios C. Kyriacou Maria Giordano Alberto Ritieni Stefania De Pascale Youssef Rouphael Rising life expectancy and the demanding modern lifestyle...
Fri Apr 03, 2020 03:00
Antioxidants, Vol. 9, Pages 298: Citrus × Clementina Hort. Juice Enriched with Its By-Products (Peels and Leaves): Chemical Composition, In Vitro Bioactivity, and Impact of Processing Antioxidants doi: 10.3390/antiox9040298 Authors: Mariarosaria Leporini Monica Rosa Loizzo Vincenzo Sicari Teresa Maria Pellicanò Antonella Reitano Annabelle Dugay Brigitte Deguin Rosa Tundis This work investigated a model for the reuse of Citrus × clementina Hort. by-products...
Fri Apr 03, 2020 03:00
Atmosphere, Vol. 11, Pages 353: Late 21st Century Projected Changes in the Relationship between Precipitation, African Easterly Jet, and African Easterly Waves Atmosphere doi: 10.3390/atmos11040353 Authors: Ibourahima Kebe Ismaila Diallo Mouhamadou Bamba Sylla Fernando De Sales Arona Diedhiou The present study utilizes three high-resolution simulations from the Regional Climate Model version 4 (RegCM4) to examine the late 21st century changes (2080–2099) in the...
Sat Apr 04, 2020 03:00
Atmosphere, Vol. 11, Pages 352: Atmospheric Dispersion Modelling at the London VAAC: A Review of Developments since the 2010 Eyjafjallajökull Volcano Ash Cloud Atmosphere doi: 10.3390/atmos11040352 Authors: Frances M. Beckett Claire S. Witham Susan J. Leadbetter Ric Crocker Helen N. Webster Matthew C. Hort Andrew R. Jones Benjamin J. Devenish David J. Thomson It has been 10 years since the ash cloud from the eruption of Eyjafjallajökull caused unprecedented...
Sat Apr 04, 2020 03:00
Atmosphere, Vol. 11, Pages 351: Bioburden Assessment by Passive Methods on a Clinical Pathology Service in One Central Hospital from Lisbon: What Can it Tell Us Regarding Patients and Staff Exposure? Atmosphere doi: 10.3390/atmos11040351 Authors: Carla Viegas Magdalena Twarużek Raquel Lourenço Marta Dias Beatriz Almeida Liliana Aranha Caetano Elisabete Carolino Anita Quintal Gomes Robert Kosicki Ewelina Soszczyńska Susana Viegas The assessment and control...
Fri Apr 03, 2020 03:00
Behavioral Sciences, Vol. 10, Pages 73: IMPULSE Moment-by-Moment Test: An Implicit Measure of Affective Responses to Audiovisual Televised or Digital Advertisements Behavioral Sciences doi: 10.3390/bs10040073 Authors: Calvert Trufil Pathak Fulcher IMPULSE is a novel method for detecting affective responses to dynamic audiovisual content. It is an implicit reaction time test that is carried out while an audiovisual clip (e.g., a television commercial) plays in the background...
Sun Apr 05, 2020 03:00
Behavioral Sciences, Vol. 10, Pages 72: Brief Exposure to Infants Activates Social and Intergroup Vigilance Behavioral Sciences doi: 10.3390/bs10040072 Authors: Bobby Cheon Gianluca Esposito Among humans, simply looking at infants can activate affiliative and nurturant behaviors. However, it remains unknown whether mere exposure to infants also activates other aspects of the caregiving motivational system, such as generalized defensiveness in the absence of immediate threats. Here,...
Fri Apr 03, 2020 03:00
Beverages, Vol. 6, Pages 22: Potential Application of Tetrapleura tetraptera and Hibiscus sabdariffa (Malvaceae) in Designing Highly Flavoured and Bioactive Pito with Functional Properties Beverages doi: 10.3390/beverages6020022 Authors: Parise Adadi Osman N. Kanwugu Sorghum beer (pito) is an indigenous alcoholic beverage peculiar to northern Ghana and parts of other West African countries. It is overwhelmed with calories, essential amino acids (such as lysine, etc.), B-group vitamins,...
Fri Apr 03, 2020 03:00
Bioengineering, Vol. 7, Pages 34: Preparation and Characterization of Films Based on a Natural P(3HB)/mcl-PHA Blend Obtained through the Co-culture of Cupriavidus Necator and Pseudomonas Citronellolis in Apple Pulp Waste Bioengineering doi: 10.3390/bioengineering7020034 Authors: Rebocho Pereira Neves Alves Sevrin Grandfils Freitas Reis The co-culture of Cupriavidus necator DSM 428 and Pseudomonas citronellolis NRRL B-2504 was performed using apple pulp waste...
Sun Apr 05, 2020 03:00
Biology, Vol. 9, Pages 72: The Role of Prenatal Melatonin in the Regulation of Childhood Obesity Biology doi: 10.3390/biology9040072 Authors: Ivanov Evsyukova Mazzoccoli Anderson Polyakova Kvetnoy Carbone Nasyrov There is a growing awareness that pregnancy can set the foundations for an array of diverse medical conditions in the offspring, including obesity. A wide assortment of factors, including genetic, epigenetic, lifestyle, and diet can influence foetal...
Sun Apr 05, 2020 03:00
Biology, Vol. 9, Pages 71: Knockdown of N-Acetylglucosaminyltransferase-II Reduces Matrix Metalloproteinase 2 Activity and Suppresses Tumorigenicity in Neuroblastoma Cell Line Biology doi: 10.3390/biology9040071 Authors: M. Kristen Hall Austin A. Whitman Douglas A. Weidner Ruth A. Schwalbe Neuroblastoma (NB) development and progression are accompanied by changes in N-glycans attached to proteins. Here, we investigated the role of N-acetylglucosaminyltransferase-II (GnTII, MGAT2)...
Sat Apr 04, 2020 03:00
Biomedicines, Vol. 8, Pages 78: Atropine Differentially Modulates ECM Production by Ocular Fibroblasts, and Its Ocular Surface Toxicity Is Blunted by Colostrum Biomedicines doi: 10.3390/biomedicines8040078 Authors: Cristaldi Olivieri Pezzino Spampinato Lupo Anfuso Rusciano Background: The etiology and the mechanism behind atropine treatment of progressive myopia are still poorly understood. Our study addressed the role of scleral and choroidal fibroblasts...
Sun Apr 05, 2020 03:00
Biomedicines, Vol. 8, Pages 77: Persistently Worsened Tear Break-up Time and Keratitis in Unilateral Pseudophakic Eyes after a Long Postoperative Period Biomedicines doi: 10.3390/biomedicines8040077 Authors: Hanyuda Negishi Tsubota Ayaki Dry eye disease may develop and persist after cataract surgery; however, unilateral cases have not been fully documented. This cross-sectional, observational study was conducted in five eye clinics in Japan. A total of 1023 outpatients were...
Sun Apr 05, 2020 03:00
Biomedicines, Vol. 8, Pages 76: Polymerized Selenium Nanoparticles for Folate-Receptor-Targeted Delivery of Anti-Luc-siRNA: Potential for Gene Silencing Biomedicines doi: 10.3390/biomedicines8040076 Authors: Fiona Maiyo Moganavelli Singh The development of a biocompatible and nontoxic gene delivery vehicle remains a challenging task. Selenium nanoparticles (SeNPs) have the potential to increase delivery efficiency, to reduce side effects, and to improve therapeutic outcomes. In this...
Sun Apr 05, 2020 03:00
Biomedicines, Vol. 8, Pages 75: Dietary Supplementation with Chestnut (Castanea sativa) Reduces Abdominal Adiposity in FVB/n Mice: A Preliminary Study Biomedicines doi: 10.3390/biomedicines8040075 Authors: Rodrigues Ferreira Nascimento-Gonçalves Seixas Gil da Costa Martins Neuparth Pires Lanzarin Félix Venâncio Ferreira Bastos Medeiros Gaivão Rosa Oliveira The production of chestnut (Castanea sativa Miller) is mostly concentrated...
Sat Apr 04, 2020 03:00
Biomedicines, Vol. 8, Pages 74: Effectiveness of Glecaprevir/Pibrentasvir for Hepatitis C: Real-World Experience and Clinical Features of Retreatment Cases Biomedicines doi: 10.3390/biomedicines8040074 Authors: Sugiura Joshita Yamashita Yamazaki Fujimori Kimura Matsumoto Wada Mori Shibata Yoshizawa Morita Furuta Kamijo Iijima Kako Maruyama Kobayashi Komatsu Matsumura Miyabayashi Ichijo Takeuchi Koike...
Fri Apr 03, 2020 03:00
Biomolecules, Vol. 10, Pages 557: Deciphering Master Gene Regulators and Associated Networks of Human Mesenchymal Stromal Cells Biomolecules doi: 10.3390/biom10040557 Authors: Sánchez-Luis Joaquín-García Campos-Laborie Sánchez-Guijo Rivas Mesenchymal Stromal Cells (MSC) are multipotent cells characterized by self-renewal, multilineage differentiation, and immunomodulatory properties. To obtain a gene regulatory profile of human MSCs, we generated a compendium of more...
Sun Apr 05, 2020 03:00
Biomolecules, Vol. 10, Pages 554: Pig Pregnancies after Transfer of Allogeneic Embryos Show a Dysregulated Endometrial/Placental Cytokine Balance: A Novel Clue for Embryo Death? Biomolecules doi: 10.3390/biom10040554 Authors: Martinez Rubér Rodriguez-Martinez Alvarez-Rodriguez Pig embryo transfer (ET) is burdened by high embryo mortality, with cytokines playing a significant role in recruitment of immune cells during embryo attachment and placentation. We hereby tested if...
Sun Apr 05, 2020 03:00
Biomolecules, Vol. 10, Pages 555: Tick and Host Derived Compounds Detected in the Cement Complex Substance Biomolecules doi: 10.3390/biom10040555 Authors: Villar Pacheco Merino Contreras Mateos-Hernández Prado Barros-Picanço Lima-Barbero Artigas-Jerónimo Alberdi Mera Estrada-Peña Cabezas-Cruz Fuente Ticks are obligate hematophagous arthropods and vectors of pathogens affecting human and animal health worldwide. Cement is a complex...
Sun Apr 05, 2020 03:00
Biomolecules, Vol. 10, Pages 553: Chitosan Nanocomplexes for the Delivery of ENaC Antisense Oligonucleotides to Airway Epithelial Cells Biomolecules doi: 10.3390/biom10040553 Authors: Kolonko Bangel-Ruland Goycoolea Weber Nanoscale drug delivery systems exhibit a broad range of applications and promising treatment possibilities for various medical conditions. Nanomedicine is of great interest, particularly for rare diseases still lacking a curative treatment such as cystic...
Sun Apr 05, 2020 03:00
Biomolecules, Vol. 10, Pages 556: Protective Effect of Palm Oil-Derived Tocotrienol-Rich Fraction Against Retinal Neurodegenerative Changes in Rats with Streptozotocin-Induced Diabetic Retinopathy Biomolecules doi: 10.3390/biom10040556 Authors: Sadikan Nasir Agarwal Ismail : Oxidative stress plays an important role in retinal neurodegeneration and angiogenesis associated with diabetes. In this study, we investigated the effect of the tocotrienol-rich fraction (TRF), a potent...
Sun Apr 05, 2020 03:00
Biomolecules, Vol. 10, Pages 552: Strained Conformations of Nucleosides in Active Sites of Nucleoside Phosphorylases Biomolecules doi: 10.3390/biom10040552 Authors: Irina A. Il’icheva Konstantin M. Polyakov Sergey N. Mikhailov Nucleoside phosphorylases catalyze the reversible phosphorolysis of nucleosides to heterocyclic bases, giving α-d-ribose-1-phosphate or α-d-2-deoxyribose-1-phosphate. These enzymes are involved in salvage pathways of nucleoside biosynthesis....
Sun Apr 05, 2020 03:00
Biomolecules, Vol. 10, Pages 551: Bariatric Surgery Improves HDL Function Examined by ApoA1 Exchange Rate and Cholesterol Efflux Capacity in Patients with Obesity and Type 2 Diabetes Biomolecules doi: 10.3390/biom10040551 Authors: Lorkowski Brubaker Rotroff Kashyap Bhatt Nissen Schauer Aminian Smith Bariatric surgery improves glycemic control better than medical therapy; however, the effect of bariatric surgery on HDL function is not well characterized....
Sat Apr 04, 2020 03:00
Biomolecules, Vol. 10, Pages 550: Spirochete Flagella and Motility Biomolecules doi: 10.3390/biom10040550 Authors: Nakamura Spirochetes can be distinguished from other flagellated bacteria by their long, thin, spiral (or wavy) cell bodies and endoflagella that reside within the periplasmic space, designated as periplasmic flagella (PFs). Some members of the spirochetes are pathogenic, including the causative agents of syphilis, Lyme disease, swine dysentery, and leptospirosis. Furthermore,...
Sat Apr 04, 2020 03:00
Biomolecules, Vol. 10, Pages 548: The Status of p53 Oligomeric and Aggregation States in Cancer Biomolecules doi: 10.3390/biom10040548 Authors: de Oliveira Petronilho Pedrote Marques Vieira Cino Silva Despite being referred to as the guardian of the genome, when impacted by mutations, p53 can lose its protective functions and become a renegade. The malignant transformation of p53 occurs on multiple levels, such as altered DNA binding properties, acquisition of...
Sat Apr 04, 2020 03:00
Biomolecules, Vol. 10, Pages 549: Biochemical and Comparative Transcriptome Analyses Reveal Key Genes Involved in Major Metabolic Regulation Related to Colored Leaf Formation in Osmanthus fragrans ‘Yinbi Shuanghui’ during Development Biomolecules doi: 10.3390/biom10040549 Authors: Chen Yang Xie Ding Li Yue Wang Osmanthus fragrans ‘Yinbi Shuanghui’ not only has a beautiful shape and fresh floral fragrance, but also rich leaf colors that change,...
Sat Apr 04, 2020 03:00
Biomolecules, Vol. 10, Pages 546: Ranunculus bulumei Methanol Extract Exerts Anti-Inflammatory Activity by Targeting Src/Syk in NF-κB Signaling Biomolecules doi: 10.3390/biom10040546 Authors: Yo Han Hong Ji Hye Kim Jae Youl Cho (1) Background: Ranunculus bulumei is a flowering plant that belongs to the Ranunculus species. Several Ranunculus species, such as R. aquatilis and R. muricatus, have traditionally been used to treat fever and rheumatism throughout Asia, suggesting that...
Fri Apr 03, 2020 03:00
Biomolecules, Vol. 10, Pages 547: Discovery of the First Neurotransmitter Receptor: The Acetylcholine Nicotinic Receptor Biomolecules doi: 10.3390/biom10040547 Authors: Jean-Pierre Changeux The concept of pharmacological receptor was proposed at the turn of the 20th century but it took almost 70 years before the first receptor for a neurotransmitter was isolated and identified as a protein. This review retraces the history of the difficulties and successes in the identification of the...
Fri Apr 03, 2020 03:00
Biomolecules, Vol. 10, Pages 544: The Road Not Taken with Pyrrole-Imidazole Polyamides: Off-Target Effects and Genomic Binding Biomolecules doi: 10.3390/biom10040544 Authors: Jason Lin Hiroki Nagase The high sequence specificity of minor groove-binding N-methylpyrrole-N-methylimidazole polyamides have made significant advances in cancer and disease biology, yet there have been few comprehensive reports on their off-target effects, most likely as a consequence of the lack of available...
Fri Apr 03, 2020 03:00
Biomolecules, Vol. 10, Pages 542: The Contribution of Cytosolic Group IVA and Calcium-Independent Group VIA Phospholipase A2s to Adrenic Acid Mobilization in Murine Macrophages Biomolecules doi: 10.3390/biom10040542 Authors: Patricia Monge Alvaro Garrido Julio M. Rubio Victoria Magrioti George Kokotos María A. Balboa Jesús Balsinde Adrenic acid (AA), the 2-carbon elongation product of arachidonic acid, is present at significant levels in membrane phospholipids of mouse...
Fri Apr 03, 2020 03:00
Biomolecules, Vol. 10, Pages 543: Leptin Signaling Contributes to Aromatase Inhibitor Resistant Breast Cancer Cell Growth and Activation of Macrophages Biomolecules doi: 10.3390/biom10040543 Authors: Gelsomino Giordano Camera Sisci Marsico Campana Tarallo Rinaldi Fuqua Leggio Grande Bonofiglio Andò Barone Catalano Obesity represents a risk factor for breast cancer development and therapy resistance, but the molecular players underling...
Fri Apr 03, 2020 03:00
Biomolecules, Vol. 10, Pages 545: Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor Erlotinib Induces Dry Skin via Decreased in Aquaporin-3 Expression Biomolecules doi: 10.3390/biom10040545 Authors: Nobutomo Ikarashi Miho Kaneko Tomofumi Watanabe Risako Kon Makana Yoshino Takatoshi Yokoyama Riho Tanaka Naoya Takayama Hiroyasu Sakai Junzo Kamei An adverse reaction of dry skin occurs frequently during treatment with anticancer epidermal growth factor...
Fri Apr 03, 2020 03:00
Biosensors, Vol. 10, Pages 34: Investigation of Photoplethysmography Behind the Ear for Pulse Oximetry in Hypoxic Conditions with a Novel Device (SPYDR) Biosensors doi: 10.3390/bios10040034 Authors: Brian Bradke Bradford Everman Photoplethysmography (PPG) is a valuable technique for noninvasively evaluating physiological parameters. However, traditional PPG devices have significant limitations in high-motion and low-perfusion environments. To overcome these limitations, we investigated...
Sat Apr 04, 2020 03:00
Brain Sciences, Vol. 10, Pages 216: Adolescent Awkwardness: Alterations in Temporal Control Characteristics of Posture with Maturation and the Relation to Movement Exploration Brain Sciences doi: 10.3390/brainsci10040216 Authors: Felix Wachholz Federico Tiribello Maurice Mohr Steven van Andel Peter Federolf A phenomenon called adolescent awkwardness is believed to alter motor control, but underlying mechanisms remain largely unclear. Since adolescents undergo neurological...
Sun Apr 05, 2020 03:00
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