Brain Sciences, Vol. 10, Pages 215: Towards an Understanding of Control of Complex Rhythmical “Wavelike” Coordination in Humans Brain Sciences doi: 10.3390/brainsci10040215 Authors: Sanders Levitin How does the human neurophysiological system self-organize to achieve optimal phase relationships among joints and limbs, such as in the composite rhythms of butterfly and front crawl swimming, drumming, or dancing? We conducted a systematic review of literature relating to central nervous...
Sun Apr 05, 2020 03:00
Brain Sciences, Vol. 10, Pages 214: Do Adolescents Use Substances to Relieve Uncomfortable Sensations? A Preliminary Examination of Negative Reinforcement among Adolescent Cannabis and Alcohol Users Brain Sciences doi: 10.3390/brainsci10040214 Authors: April C. May Joanna Jacobus Jennifer L. Stewart Alan N. Simmons Martin P. Paulus Susan F. Tapert Alcohol and cannabis use are highly prevalent among adolescents and associated with negative consequences. Understanding motivations...
Sun Apr 05, 2020 03:00
Brain Sciences, Vol. 10, Pages 212: Language across the Lifespan in Fragile X Syndrome: Characteristics and Considerations for Assessment Brain Sciences doi: 10.3390/brainsci10040212 Authors: Anne Hoffmann Angel Wang Natalie Berger Lisa Cordeiro Rebecca Shaffer Nicole Tartaglia Craig Erickson Elizabeth Berry-Kravis While it is widely acknowledged that language development is delayed for the majority of individuals with fragile X syndrome (FXS), there has been limited...
Sat Apr 04, 2020 03:00
Brain Sciences, Vol. 10, Pages 213: Examination of Correlates to Health-Related Quality of Life in Individuals with Fragile X Syndrome Brain Sciences doi: 10.3390/brainsci10040213 Authors: Marika C. Coffman Rebecca C. Shaffer Lauren M. Schmitt Kelli C. Dominick Ernest Pedapati Angel Wang Elizabeth Berry-Kravis Nicole Tartaglia Craig A. Erickson Health-related quality of life (HRQoL) is a multidimensional concept involving physical, psychological, social, and cognitive...
Sat Apr 04, 2020 03:00
Brain Sciences, Vol. 10, Pages 211: Ex Vivo MRI Analytical Methods and Brain Pathology in Preterm Lambs Treated with Postnatal Dexamethasone † Brain Sciences doi: 10.3390/brainsci10040211 Authors: Nathanael J. Yates Kirk W. Feindel Andrew Mehnert Richard Beare Sophia Quick Dominique Blache J. Jane Pillow Rod W. Hunt Postnatal glucocorticoids such as dexamethasone are effective in promoting lung development in preterm infants, but are prescribed cautiously due to...
Fri Apr 03, 2020 03:00
Brain Sciences, Vol. 10, Pages 210: Which Effects on Neuroanatomy and Path-Integration Survive? Results of a Randomized Controlled Study on Intensive Balance Training Brain Sciences doi: 10.3390/brainsci10040210 Authors: Milos Dordevic Marco Taubert Patrick Müller Martin Riemer Jörn Kaufmann Anita Hökelmann Notger G. Müller Balancing is a complex task requiring the integration of visual, somatosensory and vestibular inputs. The vestibular system is linked to the hippocampus,...
Fri Apr 03, 2020 03:00
Cancers, Vol. 12, Pages 885: Stereotactic Radiotherapy for Ultra-Central Lung Oligometastases in Non-Small-Cell Lung Cancer Cancers doi: 10.3390/cancers12040885 Authors: Mauro Loi Davide Franceschini Luca Dominici Ciro Franzese Ilaria Chiola Tiziana Comito Marco Marzo Giacomo Reggiori Pietro Mancosu Stefano Tomatis Joost Nuyttens Marta Scorsetti Background: Stereotactic body radiotherapy (SBRT) in ultra-central (UC) lung tumors, defined in the presence...
Sun Apr 05, 2020 03:00
Cancers, Vol. 12, Pages 884: Clinical Interest of LMO2 Testing for the Diagnosis of Aggressive Large B-Cell Lymphomas Cancers doi: 10.3390/cancers12040884 Authors: Vazquez Papaleo Garcia Salido Salar Hernandez Calvo Colomo MYC rearrangements usually confer aggressive biological behavior to large B-cell lymphomas. In this study, we aimed to evaluate the relevance of LMO2 detection to the clinical approach to these tumors. First, the ability of LMO2 loss of...
Sun Apr 05, 2020 03:00
Cancers, Vol. 12, Pages 883: Biological and Clinical Significance of the CCR5/CCL5 Axis in Hepatocellular Carcinoma Cancers doi: 10.3390/cancers12040883 Authors: Singh Mishra Rivers Gordetsky Bae Singh Despite the improvement in survival for patients with liver cancer (LCa) in recent decades, only one in five patients survive for 5 years after diagnosis. Thus, there is an urgent need to find new treatment options to improve patient survival. For various cancers,...
Sun Apr 05, 2020 03:00
Cancers, Vol. 12, Pages 882: Systematic Analysis of Accuracy in Predicting Complete Oncological Resection in Pancreatic Cancer Patients—Proposal of a New Simplified Borderline Resectability Definition Cancers doi: 10.3390/cancers12040882 Authors: Louisa Bolm Katharina Mueller Katharina May Stefan Sondermann Ekaterina Petrova Hryhoriy Lapshyn Kim Christin Honselmann Dirk Bausch Sergii Zemskov Peter Bronsert Tobias Keck Steffen Deichmann Ulrich F. Wellner...
Sat Apr 04, 2020 03:00
Cancers, Vol. 12, Pages 880: Downstream Effectors of ILK in Cisplatin-Resistant Ovarian Cancer Cancers doi: 10.3390/cancers12040880 Authors: Jeyshka M. Reyes-González Blanca I. Quiñones-Díaz Yasmarie Santana Perla M. Báez-Vega Daniel Soto Fatima Valiyeva María J. Marcos-Martínez Ricardo J. Fernández-de Fernández-de Thomas Pablo E. Vivas-Mejía Despite good responses to first-line treatment with platinum-based combination chemotherapy, most ovarian cancer patients...
Sat Apr 04, 2020 03:00
Cancers, Vol. 12, Pages 881: Extracellular Vesicles Enriched with Moonlighting Metalloproteinase Are Highly Transmissive, Pro-Tumorigenic, and Trans-Activates Cellular Communication Network Factor (CCN2/CTGF): CRISPR against Cancer Cancers doi: 10.3390/cancers12040881 Authors: Yuka Okusha Takanori Eguchi Manh T. Tran Chiharu Sogawa Kaya Yoshida Mami Itagaki Eman A. Taha Kisho Ono Eriko Aoyama Hirohiko Okamura Ken-ichi Kozaki Stuart K. Calderwood Masaharu...
Sat Apr 04, 2020 03:00
Cancers, Vol. 12, Pages 879: Revisiting Cancer Stem Cells as the Origin of Cancer-Associated Cells in the Tumor Microenvironment: A Hypothetical View from the Potential of iPSCs Cancers doi: 10.3390/cancers12040879 Authors: Amira Osman Said M Afify Ghmkin Hassan Xiaoying Fu Akimasa Seno Masaharu Seno The tumor microenvironment (TME) has an essential role in tumor initiation and development. Tumor cells are considered to actively create their microenvironment during tumorigenesis...
Sat Apr 04, 2020 03:00
Cancers, Vol. 12, Pages 878: Exploring the Synergy between PARP and CHK1 Inhibition in Matched BRCA2 Mutant and Corrected Cells Cancers doi: 10.3390/cancers12040878 Authors: Hannah L Smith Lisa Prendergast Nicola J Curtin PARP inhibition results in the accumulation of DNA SSBs, causing replication stress (RS) and lesions that can only be resolved by homologous recombination repair (HRR). Defects in HRR, e.g., due to BRCA2 mutation, confer profound sensitivity to PARP inhibitor...
Sat Apr 04, 2020 03:00
Cancers, Vol. 12, Pages 877: Prognostic Impact of Tumor-Associated Macrophages on Survival Is Checkpoint Dependent in Classical Hodgkin Lymphoma Cancers doi: 10.3390/cancers12040877 Authors: Kristiina Karihtala Suvi-Katri Leivonen Oscar Brück Marja-Liisa Karjalainen-Lindsberg Satu Mustjoki Teijo Pellinen Sirpa Leppä Tumor microenvironment and immune escape affect pathogenesis and survival in classical Hodgkin lymphoma (cHL). While tumor-associated macrophage (TAM) content...
Sat Apr 04, 2020 03:00
Cancers, Vol. 12, Pages 876: MiRNAs Targeting Double Strand DNA Repair Pathways Lurk in Genomically Unstable Rare Fragile Sites and Determine Cancer Outcomes Cancers doi: 10.3390/cancers12040876 Authors: Stephan Marquardt Christin Richter Brigitte M. Pützer Stella Logotheti Double strand break (DSB) repair mechanisms guard genome integrity and their deterioration causes genomic instability. Common and rare fragile sites (CFS and RFS, respectively) are particularly vulnerable...
Fri Apr 03, 2020 03:00
Cancers, Vol. 12, Pages 875: Structure–Activity Relationships and Molecular Docking Analysis of Mcl-1 Targeting Renieramycin T Analogues in Patient-derived Lung Cancer Cells Cancers doi: 10.3390/cancers12040875 Authors: Korrakod Petsri Masashi Yokoya Sucharat Tungsukruthai Thanyada Rungrotmongkol Bodee Nutho Chanida Vinayanuwattikun Naoki Saito Matsubara Takehiro Ryo Sato Pithi Chanvorachote Myeloid cell leukemia 1 (Mcl-1) and B-cell lymphoma 2 (Bcl-2) proteins...
Fri Apr 03, 2020 03:00
Cancers, Vol. 12, Pages 872: Vinorelbine Augments Radiotherapy in Hepatocellular Carcinoma Cancers doi: 10.3390/cancers12040872 Authors: Kheng Wei Yeoh Aldo Prawira Muhammad Zafrie Bin Saad Kok Ming Lee Eric Ming Hon Lee Gee Keng Low Mohamed Hakim Bin Mohd Nasir Jun Hao Phua Wendy Wan Li Chow Iris Jiu Hia Lim Yusnita Binte Omar Rebecca Zhi Wen Ho Thi Bich Uyen Le Thanh Chung Vu Khee Chee Soo Hung Huynh There is a need to improve the effectiveness...
Fri Apr 03, 2020 03:00
Cancers, Vol. 12, Pages 873: Prognostic Impact of PD-L1 Expression in Malignant Salivary Gland Tumors as Assessed by Established Scoring Criteria: Tumor Proportion Score (TPS), Combined Positivity Score (CPS), and Immune Cell (IC) Infiltrate Cancers doi: 10.3390/cancers12040873 Authors: Hanno M. Witte Niklas Gebauer Daniela Lappöhn Vincent G. Umathum Armin Riecke Annette Arndt Konrad Steinestel Background: Malignant neoplasms of the salivary glands are rare, and therapeutic...
Fri Apr 03, 2020 03:00
Cancers, Vol. 12, Pages 874: Statin Use Decreases the Incidence of Hepatocellular Carcinoma: An Updated Meta-Analysis Cancers doi: 10.3390/cancers12040874 Authors: Antonio Facciorusso Mohamed A Abd El Aziz Siddharth Singh Sara Pusceddu Massimo Milione Luca Giacomelli Rodolfo Sacco Statins can decrease hepatocellular carcinoma (HCC) occurrence, but the magnitude and the predictors of these effects remain unclear. This meta-analysis provides a pooled estimate of the impact...
Fri Apr 03, 2020 03:00
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