IJERPH, Vol. 17, Pages 2433: Dust Events and Indoor Air Quality in Residential Homes in Kuwait International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17072433 Authors: Yufei Yuan Barrak Alahmad Choong-Min Kang Fhaid Al-Marri Venkateswarlu Kommula Walid Bouhamra Petros Koutrakis Kuwait is a developed Middle Eastern country that is impacted by frequent dust storms from regional and/or remote deserts. The effectiveness of keeping homes tightly...
IJERPH, Vol. 17, Pages 2432: The Code of the Street Fights Back! Significant Associations with Arrest, Delinquency, and Violence Withstand Psychological Confounds International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17072432 Authors: Kyle A. Burgason Matt DeLisi Mark H. Heirigs Abdi Kusow Jacob H. Erickson Michael G. Vaughn Since Anderson’s now classic, Code of the Street: Decency, Violence, and the Moral Life of the Inner City,...
IJERPH, Vol. 17, Pages 2430: A New Application of Social Impact in Social Media for Overcoming Fake News in Health International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17072430 Authors: Cristina M. Pulido Laura Ruiz-Eugenio Gisela Redondo-Sama Beatriz Villarejo-Carballido One of the challenges today is to face fake news (false information) in health due to its potential impact on people’s lives. This article contributes to a new application...
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IJMS, Vol. 21, Pages 2536: Nanoparticles Modified with Cell-Penetrating Peptides: Conjugation Mechanisms, Physicochemical Properties, and Application in Cancer Diagnosis and Therapy International Journal of Molecular Sciences doi: 10.3390/ijms21072536 Authors: Isabel Gessner Ines Neundorf Based on their tunable physicochemical properties and the possibility of producing cell-specific platforms through surface modification with functional biomolecules, nanoparticles (NPs) represent...
IJMS, Vol. 21, Pages 2535: Conditional Up-Regulation of SERCA2a Exacerbates RyR2-Dependent Ventricular and Atrial Arrhythmias International Journal of Molecular Sciences doi: 10.3390/ijms21072535 Authors: Liu Lou Smith Velez-Cortes Dillmann Knollmann Armoundas Györke Ryanodine receptor 2 (RyR2) and SERCA2a are two major players in myocyte calcium (Ca) cycling that are modulated physiologically, affected by disease and thus considered to be potential targets...
IJMS, Vol. 21, Pages 2534: In Silico Studies on Triterpenoid Saponins Permeation through the Blood–Brain Barrier Combined with Postmortem Research on the Brain Tissues of Mice Affected by Astragaloside IV Administration International Journal of Molecular Sciences doi: 10.3390/ijms21072534 Authors: Katarzyna Stępnik Wirginia Kukula-Koch As the number of central nervous system (CNS) drug candidates is constantly growing, there is a strong need for precise a priori prediction of whether...
IJMS, Vol. 21, Pages 2532: Immunotherapy in Renal Cell Carcinoma: The Future Is Now International Journal of Molecular Sciences doi: 10.3390/ijms21072532 Authors: Antoine Deleuze Judikaël Saout Frédéric Dugay Benoit Peyronnet Romain Mathieu Gregory Verhoest Karim Bensalah Laurence Crouzet Brigitte Laguerre Marc-Antoine Belaud-Rotureau Nathalie Rioux-Leclercq Solène-Florence Kammerer-Jacquet Renal cell carcinoma is the third type of urologic cancer and...
IJMS, Vol. 21, Pages 2533: Metabolomic Studies of Lipid Storage Disorders, with Special Reference to Niemann-Pick Type C Disease: A Critical Review with Future Perspectives International Journal of Molecular Sciences doi: 10.3390/ijms21072533 Authors: Benita Claire Percival Miles Gibson Philippe B. Wilson Frances M. Platt Martin Grootveld Lysosomal storage disorders (LSDs) are predominantly very rare recessive autosomal neurodegenerative diseases.Sphingolipidoses, a sub-group...
IJMS, Vol. 21, Pages 2531: Current Insights into Combination Therapies with MAPK Inhibitors and Immune Checkpoint Blockade International Journal of Molecular Sciences doi: 10.3390/ijms21072531 Authors: Min Hwa Shin Jiyoung Kim Siyoung A. Lim Jeongsoo Kim Kyung-Mi Lee The recent development of high-throughput genomics has revolutionized personalized medicine by identifying key pathways and molecular targets controlling tumor progression and survival. Mitogen-activated protein...
IJMS, Vol. 21, Pages 2530: Effect of Pharmacological Inhibition of the Catalytic Activity of Phosphatases of Regenerating Liver in Early T Cell Receptor Signaling Dynamics and IL-2 Production International Journal of Molecular Sciences doi: 10.3390/ijms21072530 Authors: Aguilar-Sopeña Hernández-Pérez Alegre-Gómez Castro-Sánchez Iglesias-Ceacero Lazo Roda-Navarro We have previously shown the delivery of phosphatase of regenerating liver-1 (PRL-1) to the immunological...
IJMS, Vol. 21, Pages 2528: CDK6 Inhibition: A Novel Approach in AML Management International Journal of Molecular Sciences doi: 10.3390/ijms21072528 Authors: Iris Z. Uras Veronika Sexl Karoline Kollmann Acute myeloid leukemia (AML) is a complex disease with an aggressive clinical course and high mortality rate. The standard of care for patients has only changed minimally over the past 40 years. However, potentially useful agents have moved from bench to bedside with the potential...
IJMS, Vol. 21, Pages 2529: Maize ZmFNSI Homologs Interact with an NLR Protein to Modulate Hypersensitive Response International Journal of Molecular Sciences doi: 10.3390/ijms21072529 Authors: Zhu Ge Ma Liu Liu Sun Wang Nucleotide binding, leucine-rich-repeat (NLR) proteins are the major class of resistance (R) proteins used by plants to defend against pathogen infection. The recognition between NLRs and their cognate pathogen effectors usually triggers a rapid...
IJMS, Vol. 21, Pages 2526: Sucrose Phosphorylase and Related Enzymes in Glycoside Hydrolase Family 13: Discovery, Application and Engineering International Journal of Molecular Sciences doi: 10.3390/ijms21072526 Authors: Jorick Franceus Tom Desmet Sucrose phosphorylases are carbohydrate-active enzymes with outstanding potential for the biocatalytic conversion of common table sugar into products with attractive properties. They belong to the glycoside hydrolase family GH13, where they...
IJMS, Vol. 21, Pages 2527: Insights into Structures and Dynamics of Flavivirus Proteases from NMR Studies International Journal of Molecular Sciences doi: 10.3390/ijms21072527 Authors: Li Kang Nuclear magnetic resonance (NMR) spectroscopy plays important roles in structural biology and drug discovery, as it is a powerful tool to understand protein structures, dynamics, and ligand binding under physiological conditions. The protease of flaviviruses is an attractive target for developing...
IJMS, Vol. 21, Pages 2525: Zeb2 Regulates Myogenic Differentiation in Pluripotent Stem Cells International Journal of Molecular Sciences doi: 10.3390/ijms21072525 Authors: Ester Sara Di Filippo Domiziana Costamagna Giorgia Giacomazzi Álvaro Cortés-Calabuig Agata Stryjewska Danny Huylebroeck Stefania Fulle Maurilio Sampaolesi Skeletal muscle differentiation is triggered by a unique family of myogenic basic helix-loop-helix transcription factors, including MyoD, MRF-4,...
IJMS, Vol. 21, Pages 2524: The Quantitative Proteome of the Cement and Adhesive Gland of the Pedunculate Barnacle, Pollicipes pollicipes International Journal of Molecular Sciences doi: 10.3390/ijms21072524 Authors: Dany Domínguez-Pérez Daniela Almeida Josef Wissing André M. Machado Lothar Jänsch Luís Filipe Castro Agostinho Antunes Vitor Vasconcelos Alexandre Campos Isabel Cunha Adhesive secretion has a fundamental role in barnacles’ survival, keeping...
IJMS, Vol. 21, Pages 2523: Pioglitazone-Mediated Peroxisome Proliferator-Activated Receptor γ Activation Aggravates Murine Immune-Mediated Hepatitis International Journal of Molecular Sciences doi: 10.3390/ijms21072523 Authors: Rike Schulte Dirk Wohlleber Ludmilla Unrau Bernd Geers Christina Metzger Annette Erhardt Gisa Tiegs Nico van Rooijen Lukas C. Heukamp Luisa Klotz Percy A. Knolle Linda Diehl The nuclear receptor peroxisome proliferator-activated...
IJMS, Vol. 21, Pages 2522: Imatinib Sets Pericyte Mosaic in the Retina International Journal of Molecular Sciences doi: 10.3390/ijms21072522 Authors: Tamás Kovács-Öller Elena Ivanova Gergely Szarka Ádám J. Tengölics Béla Völgyi Botir T. Sagdullaev The nervous system demands an adequate oxygen and metabolite exchange, making pericytes (PCs), the only vasoactive cells on the capillaries, essential to neural function. Loss of PCs is a hallmark of multiple diseases, including...
IJMS, Vol. 21, Pages 2521: Nanostructured Materials for Artificial Tissue Replacements International Journal of Molecular Sciences doi: 10.3390/ijms21072521 Authors: Pryjmaková Kaimlová Hubáček Švorčík Siegel This paper review current trends in applications of nanomaterials in tissue engineering. Nanomaterials applicable in this area can be divided into two groups: organic and inorganic. Organic nanomaterials are especially used for the preparation of highly porous scaffolds...
IJMS, Vol. 21, Pages 2520: The Cbs Locus Affects the Expression of Senescence Markers and mtDNA Copy Number, but not Telomere Dynamics in Mice International Journal of Molecular Sciences doi: 10.3390/ijms21072520 Authors: Utyro Perła-Kaján Jakubowski Cystathionine β-synthase (CBS) is a housekeeping enzyme that catalyzes the first step of the homocysteine to cysteine transsulfuration pathway. Homozygous deletion of the Cbs gene in mice causes severe hyperhomocysteinemia...
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