Studies about a formal analogy between the gravitational and the electromagnetic fields lead to the notion of Gravitoelectromagnetism (GEM) to describe gravitation. In fact, the GEM equations correspond to the weak-field approximation of the gravitation field. Here, a non-abelian extension of the GEM theory is considered. Using the Thermo Field Dynamics (TFD) formalism to introduce temperature effects, some interesting physical phenomena are investigated. The non-abelian GEM Stefan-Boltzmann law...
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In this paper, we investigate infinitely many solutions for the generalized periodic boundary value problem under the potential function without the evenness assumption and obtain two new existence results by the multiple critical point theorem. Meanwhile, we give two corollaries for the periodic solutions of second-order Hamiltonian systems and an example that illustrates our results.
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The purpose of this study was to investigate the expression levels of the immune checkpoint proteins, programmed cell death-ligand 1 (PD-L1), B7-H3, B7-H4, and V-domain Ig suppressor of T cell activation (VISTA), as well as the significance thereof, in clear cell carcinoma (CCC) of the cervix (a rare histological subtype of cervical cancer). We also compared the expression statuses of these biomarkers in cervical CCCs with those in cervical squamous cell carcinomas (SCCs). We evaluated the expression...
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Background. Progressive β-cell dysfunction, a major characteristic of type 2 diabetes (T2D), is closely related to the infiltration of inflammatory macrophages within islets. Mesenchymal stem cells (MSCs) have been identified to alleviate β-cell dysfunction by modulating macrophage phenotype in T2D, but the restoration of β-cells by a single MSC infusion is relatively transient. Decitabine (DAC) has been reported to polarize macrophages towards the anti-inflammatory phenotype at low doses. We therefore...
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Active peptides have good effectiveness in controlling or preventing many diseases. Compound active peptides (CAP) obtained from animal, plant, and sea food proteins were used in this study to explore their effects on antioxidation, anti-inflammation, and antihyperglycemia in vitro and in vivo. The results demonstrated that 10 μg/mL CAP could increase cell viability () and decrease reactive oxygen species (ROS) levels and cell apoptosis () when WRL68 cells were induced by H2O2 for 6 h. Moreover,...
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In order to explore the specimen failure characteristics during rock-burst under different gradient stress conditions, in this paper, a novel experimental technique was proposed; a common series of tests under two gradient stress paths were conducted on rock similar material specimens using the true-triaxial gradient and hydraulic-pneumatic combined test apparatus. And plaster was used as the rock similar material. In the experimental process, several rock-burst debris with area sizes of 100 mm2...
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Peripartum pancreatitis is a rare clinical condition that occurs usually in the third trimester of pregnancy. Pancreatitis is usually secondary to gallstones, and it can lead to life-threatening and rare complications. We report a case of necrotizing postpartum pancreatitis that developed abdominal compartment syndrome (ACS) in early course, posterior reversible encephalopathy syndrome (PRES), and splanchnic and extrasplanchnic thrombosis later on. Case. 31-year-old female, one week after delivery,...
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Liver cancer is thought as the most common human malignancy worldwide, and hepatocellular carcinoma (HCC) accounts for nearly 90% liver cancer. Due to its poor early diagnosis and limited treatment, HCC has therefore become the most lethal malignant cancers in the world. Recently, molecular targeted therapies showed great promise in the treatment of HCC, and novel molecular therapeutic targets is urgently needed. KIF15 is a microtubule-dependent motor protein involved in multiple cell processes,...
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Acute kidney injury (AKI), a clinical syndrome, is a sudden onset of kidney failure that severely affects the kidney tubules. One potential treatment is dexmedetomidine (DEX), a highly selective α2-adrenoreceptor agonist that is used as an anesthetic adjuvant. It also has anti-inflammatory, neuroprotective, and sympatholytic qualities. The aim of this study was to establish whether DEX also offers protection against ischemia and reperfusion- (I/R-) induced AKI in rats. An intraperitoneal injection...
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Systemic lupus erythematosus (SLE) is a polymorphic, multisystemic autoimmune disease that causes multiorgan damage in which cellular communication occurs through the involvement of autoantibodies directed against autoantigen production. Mesenchymal stem cells (MSCs), which have strong protective and immunomodulatory abilities, are obtained not only from bone marrow but also from medical waste such as adipose tissue and umbilical cord tissue and have been recognized as a promising tool for the treatment...
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Aging is a predominant risk factor for many chronic conditions. Stem cell dysfunction plays a pivotal role in the aging process. Prelamin A, an abnormal processed form of the nuclear lamina protein lamin A, has been reported to trigger premature senescence. However, the mechanism driving stem cell dysfunction is still unclear. In this study, we found that while passaging subchondral bone mesenchymal stem cells (SCB-MSCs) in vitro, prelamin A accumulation occurred concomitantly with an increase in...
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This randomized controlled study is aimed at investigating the effects of long-term use of insoles with a toe-grip bar on the balance, walking, and running of preschool children. Fifty-two preschool children were randomly assigned to an intervention group or control group. Children included in the intervention group wore shoes with insoles that had a toe-grip bar, and those in the control group wore shoes with regular insoles without a toe-grip bar for 4 weeks while they were at school. The center...
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Protein phosphorylation is a posttranslational modification that is essential for normal cellular processes; however, abnormal phosphorylation is one of the prime causes for alteration of many structural, functional, and regulatory proteins in disease conditions. In cancer, changes in the states of protein phosphorylation in tyrosine residues have been more studied than phosphorylation in threonine or serine residues, which also undergo alterations with greater predominance. In general, serine phosphorylation...
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This retrospective study investigated whether podocalyxin expression in renal biopsies and urine of patients with diabetic nephropathy (DN) is associated with renal function. This retrospective study included 32 patients with nephropathy, secondary to type 2 diabetes treated at the First Hospital of Lanzhou University (January 2010 to January 2015). Compared with the control group, the DN group had a significantly lower renal expression of podocalyxin and higher urinary podocalyxin/creatinine ratio....
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Objective. A survival risk assessment model associated with a lung adenocarcinoma (LUAD) microenvironment was established and evaluated to identify effective independent prognostic factors for LUAD. Methods. The public data were downloaded from the TCGA database, and ESTIMATE prediction software was used to score immune cells and stromal cells for tumor purity prediction. The samples were divided into the high-score group and the low-score group by the median value of the immune score (or stromal...
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Gastric glomus tumors (GGTs) are rare mesenchymal tumors. Most glomus tumors occur in the distal parts of the extremities. Here, we retrospectively analyzed the features of GGTs from two institutions. The histologic and clinical findings of all GGT cases from 2009 to 2018 were reviewed. The most common location was the antrum, the mean age of patients was 49.3 years, and the mean tumor size was 2.1 cm. Microscopically, small, round cell nodules surrounded the expansion of blood vessels in a nest...
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Background. The Lateral Step-Up Test (LSUT) has been used to evaluate the closed kinetic chain functional muscle strength in people with orthopaedic or neurological conditions. No study has systematically investigated the intrarater, interrater, and test-retest reliabilities of this measure in stroke survivors. In addition, correlations of the LSUT count with other stroke-specific impairment and function measurements remain unidentified. Objectives. This study was aimed at investigating (1) the interrater,...
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Peroxiredoxin 2 (PRDX2), a member of the peroxiredoxin family of antioxidant enzymes, has been revealed to be an important player in cancer progression. However, the biological role of PRDX2 in the progression of non-small cell lung cancer (NSCLC) is poor reported. In the present study, the loss-of-function experiments were performed to investigate the specific role of PRDX2 in the growth and invasion of NSCLC. The results revealed that knockdown of PRDX2 by siRNA interference significantly suppressed...
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Background. Low back pain (LBP) is common in the elderly and an appropriate intervention for LBP management should be investigated. The aim of this study is to investigate the potential of mud-heat intervention combined with core exercise as an alternative intervention for relieving pain and improving motor function in individuals with nonspecific chronic LBP. Methods. Thirty-one individuals with chronic nonspecific LBP were randomly allocated to either the intervention group (n = 16) or the control...
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Electronic cigarette, or vaping product use-associated lung injury (EVALI), is a group of lung disorders associated with vaping and e-cigarette products that has previously been categorized as a diagnosis of exclusion and best described as an exogenous lipoid pneumonia or chemical pneumonitis. Here, we describe the onset of an exogenous cause of lipoid pneumonia in an otherwise healthy patient using cannabis-containing electronic cigarettes. We explore similarities in the clinical case, define a...
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Objective. Nowadays, body mass index (BMI) is used to evaluate the risk stratification of obesity-related pregnancy complications in clinics. However, BMI cannot reflect fat distribution or the proportion of adipose to nonadipose tissue. The objective of this study is to evaluate the association of maternal first or second trimester central obesity with the risk of GDM. Research Design and Methods. We searched in PubMed, Embase, and Web of Science for English-language medical literature published...
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Diabetic hearts are more susceptible to myocardial ischemia/reperfusion (I/R) injury and less sensitive to ischemic postconditioning (IPostC), but the underlying mechanisms remain unclear. PKCβ2 is preferentially overactivated in diabetic myocardium, in which autophagy status is abnormal. This study determined whether hyperglycemia-induced PKCβ2 activation resulted in autophagy abnormality and compromised IPostC cardioprotection in diabetes. We found that diabetic rats showed higher cardiac PKCβ2...
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In understanding the hydraulic characteristics of river system flow, the hydraulic simulation models are essential tools. This study submits the results of the proposition of a hydraulic model in order to determine the roughness coefficient (Manning’s coefficient n) of the Tigris River along 3.5 km within the Maysan Governorate, south of Iraq. HEC-RAS software was the simulation tool used in this study. The HEC-RAS model was adopted, calibrated, and validated in adopting two sets of observed water...
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Evodiamine (Evo) is an indole alkaloid extracted from the traditional Chinese medicinal herb Evodia rutaecarpa. Evo may regulate gastrointestinal motility, but the evidence is insufficient, and the mechanisms remain unknown. The aim of this study was to investigate the effect of Evo on colonic motility of rats and the underlying mechanisms in vitro. Rat colonic muscle was exposed to Evo (10 and 100 μM) followed by immunohistochemistry of cholecystokinin receptor 1 (CCK1R). Muscle contractions were...
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Purpose. The study is aimed at exploring the popularity, impact, and usefulness of using YouTube in learning anatomy as perceived by Jordanian medical students studying at Jordan University of Science and Technology. Methods. The present work is a cross-sectional questionnaire-based study. First-, second-, and third-year medical students were invited to complete an anonymous questionnaire. Students’ responses were numerically coded, and the results were analyzed to reveal any statistically significant...
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Electromagnetic source imaging (ESI) techniques have become one of the most common alternatives for understanding cognitive processes in the human brain and for guiding possible therapies for neurological diseases. However, ESI accuracy strongly depends on the forward model capabilities to accurately describe the subject’s head anatomy from the available structural data. Attempting to improve the ESI performance, we enhance the brain structure model within the individual-defined forward problem formulation,...
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The type III secretion system (T3SS) is a special protein delivery system in Gram-negative bacteria which delivers T3SS-secreted effectors (T3SEs) to host cells causing pathological changes. Numerous experiments have verified that T3SEs play important roles in many biological activities and in host-pathogen interactions. Accurate identification of T3SEs is therefore essential to help understand the pathogenic mechanism of bacteria; however, many existing biological experimental methods are time-consuming...
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The purpose of this study is the application of pressure sensors in diagnostics and evaluation of the accuracy diagnostics of lumbar disc herniation at levels L4/L5 and L5/S1 using the aforementioned platform. The motivation behind the idea to apply the pressure measurement platform is the fact that the motor weakness of plantar and dorsal flexia of the feet is one of the absolute indications for the operative treatment of patients with lumbar disc herniation at the indicated levels. In patients,...
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Publication date: Available online 5 April 2020Source: Journal of Infection and ChemotherapyAuthor(s): Koh Okamoto, Alafate Ayibieke, Ryoichi Saito, Kenichi Ogura, Yuki Magara, Reiko Ueda, Hina Ogawa, Shuji Hatakeyama
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Publication date: Available online 2 April 2020Source: Journal of Infection and ChemotherapyAuthor(s): Masato Kai, Kyohei Miyamoto, Keiichiro Akamatsu, Ai Tsujita, Machiko Nishio
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Publication date: Available online 2 April 2020Source: Journal of Infection and ChemotherapyAuthor(s): Hideyuki Ikematsu, Naoki Kawai, Naoki Tani, Yong Chong, Takuma Bando, Norio Iwaki, Seizaburo Kashiwagi
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Publication date: Available online 2 April 2020Source: Journal of Infection and ChemotherapyAuthor(s): Kozue Kishii, Masakaze Hamada, Kotaro Aoki, Kengo Ito, Joh Onodera, Yoshikazu Ishii, Kazuhiro Tateda
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Publication date: Available online 2 April 2020Source: Journal of Infection and ChemotherapyAuthor(s): Hironori Sadamatsu, Koichiro Takahashi, Hiroki Tashiro, Shinsuke Ogusu, Tetsuro Haraguchi, Chiho Nakashima, Tomomi Nakamura, Naoko Sueoka-Aragane
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JSAN, Vol. 9, Pages 19: Advancement of Routing Protocols and Applications of Underwater Wireless Sensor Network (UWSN)—A Survey Journal of Sensor and Actuator Networks doi: 10.3390/jsan9020019 Authors: Khandaker Foysal Haque K. Habibul Kabir Ahmed Abdelgawad Water covers a greater part of the Earth’s surface. However, little knowledge has been achieved regarding the underwater world as most parts of it remain unexplored. Oceans, including other water bodies, hold substantial...
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Publication date: Available online 4 April 2020Source: Journal of BiomechanicsAuthor(s): Anne D. Koelewijn, Antonie J. van den Bogert
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Publication date: Available online 4 April 2020Source: Journal of BiomechanicsAuthor(s): Nora Millor, Eduardo L. Cadore, Marisol Gómez, Alicia Martínez, Pablo Lecumberri, Jon Martirikorena, Fernando Idoate, Mikel Izquierdo
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Publication date: 16 April 2020Source: Journal of Biomechanics, Volume 103Author(s):
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Publication date: Available online 3 April 2020Source: Journal of BiomechanicsAuthor(s): Elaine C. Schmidt, Todd J. Hullfish, Kathryn M. O'Connor, Michael W. Hast, Josh R. Baxter
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