IJERPH, Vol. 17, Pages 3789: A One Health Perspective on the Human–Companion Animal Relationship with Emphasis on Zoonotic Aspects International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17113789 Authors: Overgaauw Vinke Hagen Lipman Over time the human–animal bond has been changed. For instance, the role of pets has changed from work animals (protecting houses, catching mice) to animals with a social function, giving companionship....
Wed May 27, 2020 03:00
IJERPH, Vol. 17, Pages 3791: Health of Youth in Transition in Hong Kong International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17113791 Authors: Leung Folake Bailey Lai Chan Lam This study aimed to examine the impact of individual (level of vigorous physical activity (VPA) and frequency of using sports and recreation facilities), interpersonal (perceived social cohesion (PSC)), and neighborhood environmental (availability of sports and...
Wed May 27, 2020 03:00
IJERPH, Vol. 17, Pages 3788: A Study on Characteristic Emission Factors of Exhaust Gas from Diesel Locomotives International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17113788 Authors: Kim Park Kim Heo Park Chong Use of diesel locomotives in transport is gradually decreasing due to electrification and the introduction of high-speed electric rail. However, in Korea, up to 30% of the transportation of passengers and cargo still uses diesel...
Wed May 27, 2020 03:00
IJERPH, Vol. 17, Pages 3786: Presence and Health Risks of Obsolete and Emerging Pesticides in Paddy Rice and Soil from Thailand and China International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17113786 Authors: Naranun Khammanee Yanling Qiu Nipapun Kungskulniti Anders Bignert Yuan Meng Zhiliang Zhu Zebene Lekew Teffera Organochlorine (OCPs) and organophosphorus pesticides (OPPs) have been intensively applied in rice paddy field farming...
Wed May 27, 2020 03:00
IJERPH, Vol. 17, Pages 3787: Cigarette, E-Cigarette and Waterpipe Use among Young Adults: Differential Cognitions about These Three Forms of Smoking International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17113787 Authors: Sullman Gras Kagialis Papageorgi Font-Mayolas Background: Polytobacco use is common among young adults. The purpose of the present study was to investigate a number of cognitions related to the use of three tobacco products...
Wed May 27, 2020 03:00
IJMS, Vol. 21, Pages 3822: Reference Ranges of 8-Isoprostane Concentrations in Exhaled Breath Condensate (EBC): A Systematic Review and Meta-Analysis International Journal of Molecular Sciences doi: 10.3390/ijms21113822 Authors: Shoman Wild Hemmendinger Graille Sauvain Hopf Guseva Canu Isoprostanes are physiopathologic mediators of oxidative stress, resulting in lipid peroxidation. 8-isoprostane seems particularly useful for measuring oxidative stress damage....
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IJMS, Vol. 21, Pages 3820: Mitochondrial OXPHOS Biogenesis: Co-Regulation of Protein Synthesis, Import, and Assembly Pathways International Journal of Molecular Sciences doi: 10.3390/ijms21113820 Authors: Tang Thompson Taylor Oláhová The assembly of mitochondrial oxidative phosphorylation (OXPHOS) complexes is an intricate process, which—given their dual-genetic control—requires tight co-regulation of two evolutionarily distinct gene expression machineries....
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IJMS, Vol. 21, Pages 3821: Molecular Aspects and Treatment of Iron Deficiency in the Elderly International Journal of Molecular Sciences doi: 10.3390/ijms21113821 Authors: Romano Paglia Bellanti Villani Sangineto Vendemiale Serviddio Iron deficiency (ID) is the most frequent nutritional deficiency in the whole population worldwide, and the second most common cause of anemia in the elderly. The prevalence of anemia is expecting to rise shortly, because of an ageing...
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IJMS, Vol. 21, Pages 3819: Steroids and TRP Channels: A Close Relationship International Journal of Molecular Sciences doi: 10.3390/ijms21113819 Authors: Méndez-Reséndiz Enciso-Pablo González-Ramírez Juárez-Contreras Rosenbaum Morales-Lázaro Transient receptor potential (TRP) channels are remarkable transmembrane protein complexes that are essential for the physiology of the tissues in which they are expressed. They function as non-selective cation channels allowing...
Wed May 27, 2020 03:00
IJMS, Vol. 21, Pages 3818: Phosphorylation Sites in Protein Kinases and Phosphatases Regulated by Formyl Peptide Receptor 2 Signaling International Journal of Molecular Sciences doi: 10.3390/ijms21113818 Authors: Annunziata Parisi Esposito Fabbrocini Ammendola Cattaneo FPR1, FPR2, and FPR3 are members of Formyl Peptides Receptors (FPRs) family belonging to the GPCR superfamily. FPR2 is a low affinity receptor for formyl peptides and it is considered the most promiscuous...
Wed May 27, 2020 03:00
IJMS, Vol. 21, Pages 3810: Association of A Novel Splice Site Mutation in P/Q-Type Calcium Channels with Childhood Epilepsy and Late-Onset Slowly Progressive Non-Episodic Cerebellar Ataxia International Journal of Molecular Sciences doi: 10.3390/ijms21113810 Authors: Claudia Stendel Maria Cristina D’Adamo Manuela Wiessner Marina Dusl Marta Cenciarini Silvia Belia Ehsan Nematian-Ardestani Peter Bauer Jan Senderek Thomas Klopstock Mauro Pessia Episodic ataxia...
Wed May 27, 2020 03:00
IJMS, Vol. 21, Pages 3817: Erythropoietin Mediated Bone Loss in Mice Is Dose-Dependent and Mostly Irreversible International Journal of Molecular Sciences doi: 10.3390/ijms21113817 Authors: Albert Kolomansky Sahar Hiram-Bab Nathalie Ben-Califa Tamar Liron Naamit Deshet-Unger Moshe Mittelman Howard Oster Martina Rauner Ben Wielockx Drorit Neumann Yankel Gabet Recent studies have demonstrated that erythropoietin (EPO) treatment in mice results in trabecular...
Wed May 27, 2020 03:00
IJMS, Vol. 21, Pages 3816: Exercise Oncology and Immuno-Oncology; A (Future) Dynamic Duo International Journal of Molecular Sciences doi: 10.3390/ijms21113816 Authors: Holmen Olofsson Jensen Idorn thor Straten Recent advances in clinical oncology is based on exploiting the capacity of the immune system to combat cancer: immuno-oncology. Thus, immunotherapy of cancer is now used to treat a variety of malignant diseases. A striking feature is that even patients with late-stage...
Wed May 27, 2020 03:00
IJMS, Vol. 21, Pages 3814: Urinary MicroRNAs as Potential Markers for Non-Invasive Diagnosis of Bladder Cancer International Journal of Molecular Sciences doi: 10.3390/ijms21113814 Authors: Erdmann Salomo Klimova Heberling Lohse-Fischer Fuehrer Thomas Roeder Froehner Wirth Fuessel Currently, voided urine cytology (VUC) serves as the gold standard for the detection of bladder cancer (BCa) in urine. Despite its high specificity, VUC has shortcomings...
Wed May 27, 2020 03:00
IJMS, Vol. 21, Pages 3813: Empowering Shotgun Mass Spectrometry with 2DE: A HepG2 Study International Journal of Molecular Sciences doi: 10.3390/ijms21113813 Authors: Kiseleva Ponomarenko Poverennaya One of the major goals of the Chromosome-Centric Human Proteome Project (C-HPP) is to catalog and annotate a myriad of heterogeneous proteoforms, produced by ca. 20 thousand genes. To achieve a detailed and personalized understanding into proteomes, we suggest using a customized...
Wed May 27, 2020 03:00
IJMS, Vol. 21, Pages 3815: Disruption of the Auxin Gradient in the Abscission Zone Area Evokes Asymmetrical Changes Leading to Flower Separation in Yellow Lupine International Journal of Molecular Sciences doi: 10.3390/ijms21113815 Authors: Kućko Wilmowicz Pokora Alché How auxin transport regulates organ abscission is a long-standing and intriguing question. Polar auxin transport across the abscission zone (AZ) plays a more important role in the regulation of abscission...
Wed May 27, 2020 03:00
IJMS, Vol. 21, Pages 3811: The FT-IR and Raman Spectroscopies as Tools for Biofilm Characterization Created by Cariogenic Streptococci International Journal of Molecular Sciences doi: 10.3390/ijms21113811 Authors: Gieroba Krysa Wojtowicz Wiater Pleszczyńska Tomczyk Sroka-Bartnicka Fourier transform infrared (FT-IR) and Raman spectroscopy and mapping were applied to the analysis of biofilms produced by bacteria of the genus Streptococcus. Bacterial biofilm, also...
Wed May 27, 2020 03:00
IJMS, Vol. 21, Pages 3809: Cannabinoid Receptor Type 2: A Possible Target in SARS-CoV-2 (CoV-19) Infection? International Journal of Molecular Sciences doi: 10.3390/ijms21113809 Authors: Rossi Tortora Argenziano Di Paola Punzo In late December 2019, a novel coronavirus (SARS-CoV-2 or CoV-19) appeared in Wuhan, China, causing a global pandemic. SARS-CoV-2 causes mild to severe respiratory tract inflammation, often developing into lung fibrosis with thrombosis in pulmonary...
Wed May 27, 2020 03:00
IJMS, Vol. 21, Pages 3808: Impact of a Histone Deacetylase Inhibitor—Trichostatin A on Neurogenesis after Hypoxia-Ischemia in Immature Rats International Journal of Molecular Sciences doi: 10.3390/ijms21113808 Authors: Zalewska Jaworska Sypecka Ziemka-Nalecz Hypoxia-ischemia (HI) in the neonatal brain frequently results in neurologic impairments, including cognitive disability. Unfortunately, there are currently no known treatment options to minimize ischemia-induced neural...
Wed May 27, 2020 03:00
IJMS, Vol. 21, Pages 3812: Pulmonary Delivery of Fenretinide: A Possible Adjuvant Treatment In COVID-19 International Journal of Molecular Sciences doi: 10.3390/ijms21113812 Authors: Orienti Gentilomi Farruggia At present, there is no vaccine or effective standard treatment for severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection (or coronavirus disease-19 (COVID-19)), which frequently leads to lethal pulmonary inflammatory responses. COVID-19 pathology is...
Wed May 27, 2020 03:00
IJMS, Vol. 21, Pages 3772: Association between P2X7 Polymorphisms and Post-Transplant Outcomes in Allogeneic Haematopoietic Stem Cell Transplantation International Journal of Molecular Sciences doi: 10.3390/ijms21113772 Authors: Koldej Perera Collins Ritchie Allogeneic stem cell transplantation (alloSCT) is a highly effective treatment method for haematologic malignancies. However, infection of acute organ dysfunction and graft versus host disease (GVHD) impact negatively...
Wed May 27, 2020 03:00
IJMS, Vol. 21, Pages 3806: Participation of Somatic Stem Cells, Labeled by a Unique Antibody (A3) Recognizing both N-glycan and Peptide, to Hair Follicle Cycle and Cutaneous Wound Healing in Rats International Journal of Molecular Sciences doi: 10.3390/ijms21113806 Authors: Katou-Ichikawa Nishina Tanaka Takenaka Izawa Kuwamura Yamate A monoclonal antibody (A3) was generated by using rat malignant fibrous histiocytoma (MFH) cells as the antigen. Generally, MFH...
Wed May 27, 2020 03:00
IJMS, Vol. 21, Pages 3790: The Proliferation and Differentiation of Adipose-Derived Stem Cells in Neovascularization and Angiogenesis International Journal of Molecular Sciences doi: 10.3390/ijms21113790 Authors: Hutchings Janowicz Moncrieff Dompe Strauss Kocherova Nawrocki Kruszyna Wąsiatycz Antosik Shibli Mozdziak Perek Krasiński Kempisty Nowicki Neovascularization and angiogenesis are vital processes in the repair of damaged...
Wed May 27, 2020 03:00
IJMS, Vol. 21, Pages 3807: Improvement of Impaired Motor Functions by Human Dental Exfoliated Deciduous Teeth Stem Cell-Derived Factors in a Rat Model of Parkinson’s Disease International Journal of Molecular Sciences doi: 10.3390/ijms21113807 Authors: Chen Lai Chien Lee Lai Ma Shiau Wang Parkinson's disease (PD) is a long-term degenerative disease of the central nervous system (CNS) that primarily affects the motor system. So far there is no effective treatment...
Wed May 27, 2020 03:00
IJMS, Vol. 21, Pages 3804: Molecular Research on Platelet Activity in Health and Disease International Journal of Molecular Sciences doi: 10.3390/ijms21113804 Authors: Catani Savini Gasperi This editorial summarizes and discusses the themes of eleven articles (five reviews and six original studies) published in the Special Issue “Molecular Research On Platelet Activity in Health and Disease”. They give an international picture of the up-to-date understanding...
Wed May 27, 2020 03:00
IJMS, Vol. 21, Pages 3803: Identification of Selective Novel Hits against Plasmodium falciparum Prolyl tRNA Synthetase Active Site and a Predicted Allosteric Site Using in silico Approaches International Journal of Molecular Sciences doi: 10.3390/ijms21113803 Authors: Nyamai Tastan Bishop Recently, there has been increased interest in aminoacyl tRNA synthetases (aaRSs) as potential malarial drug targets. These enzymes play a key role in protein translation by the addition of amino...
Wed May 27, 2020 03:00
IJMS, Vol. 21, Pages 3805: Bevacizumab or PARP-Inhibitors Maintenance Therapy for Platinum-Sensitive Recurrent Ovarian Cancer: A Network Meta-Analysis International Journal of Molecular Sciences doi: 10.3390/ijms21113805 Authors: Bartoletti Pelizzari Gerratana Bortot Lombardi Nicoloso Scalone Giorda Baldassarre Sorio Puglisi Introduction: Targeted agents such as bevacizumab (BEV) or poly (ADP-ribose) polymerase inhibitors (PARPi) which have been...
Wed May 27, 2020 03:00
IJMS, Vol. 21, Pages 3801: CRISPR/Cas9-Mediated Gene Correction to Understand ALS International Journal of Molecular Sciences doi: 10.3390/ijms21113801 Authors: Yun Ha Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease caused by the death of motor neurons in the spinal cord and brainstem. ALS has a diverse genetic origin; at least 20 genes have been shown to be related to ALS. Most familial and sporadic cases of ALS are caused by variants of the SOD1, C9orf72, FUS,...
Wed May 27, 2020 03:00
IJMS, Vol. 21, Pages 3802: Looking for a Treatment for the Early Stage of Alzheimer’s Disease: Preclinical Evidence with Co-Ultramicronized Palmitoylethanolamide and Luteolin International Journal of Molecular Sciences doi: 10.3390/ijms21113802 Authors: Facchinetti Valenza Bronzuoli Menegoni Ratano Steardo Campolongo Scuderi Background: At the earliest stage of Alzheimer’s disease (AD), although patients are still asymptomatic, cerebral alterations...
Wed May 27, 2020 03:00
IJMS, Vol. 21, Pages 3799: Isolation of Human Small Extracellular Vesicles and Tracking of their Uptake by Retinal Pigment Epithelial Cells In Vitro International Journal of Molecular Sciences doi: 10.3390/ijms21113799 Authors: Irene C. Marcu Naja Eberhard Anaïs Yerly Verena Balmer Andrew Hemphill Helga Mogel Véronique Gaschen Michael H. Stoffel Jasmin Bluteau Small extracellular vesicles (EVs) are among the most frequently investigated EVs and play major roles...
Wed May 27, 2020 03:00
IJMS, Vol. 21, Pages 3800: High Expression of Cannabinoid Receptor 2 on Cytokine-Induced Killer Cells and Multiple Myeloma Cells International Journal of Molecular Sciences doi: 10.3390/ijms21113800 Authors: Garofano Schmidt-Wolf Multiple myeloma (MM) is characterized by aberrant bone marrow plasma cell (PC) proliferation and is one of the most common hematological malignancies. The potential effect of cannabinoids on the immune system and hematological malignancies has been poorly...
Wed May 27, 2020 03:00
IJMS, Vol. 21, Pages 3793: Prediction of Novel Inhibitors of the Main Protease (M-pro) of SARS-CoV-2 through Consensus Docking and Drug Reposition International Journal of Molecular Sciences doi: 10.3390/ijms21113793 Authors: Gimeno Mestres-Truyol Ojeda-Montes Macip Saldivar-Espinoza Cereto-Massagué Pujadas Garcia-Vallvé Since the outbreak of the COVID-19 pandemic in December 2019 and its rapid spread worldwide, the scientific community has been under pressure...
Wed May 27, 2020 03:00
IJMS, Vol. 21, Pages 3797: Alteration of Electron Acceptor Preferences in the Oxidative Half-Reaction of Flavin-Dependent Oxidases and Dehydrogenases International Journal of Molecular Sciences doi: 10.3390/ijms21113797 Authors: Hiraka Tsugawa Sode In this review, recent progress in the engineering of the oxidative half-reaction of flavin-dependent oxidases and dehydrogenases is discussed, considering their current and future applications in bioelectrochemical studies, such...
Wed May 27, 2020 03:00
IJMS, Vol. 21, Pages 3796: Liver Fibrosis and Inflammation under the Control of ERK2 International Journal of Molecular Sciences doi: 10.3390/ijms21113796 Authors: Kuo-Shyang Jeng Ssu-Jung Lu Chih-Hsuan Wang Chiung-Fang Chang Chronic liver injury could lead the formation of liver fibrosis, eventually some would develop to hepatocellular carcinoma (HCC), one of the leading malignancies worldwide. The aim of the study is to dissect the role of extracellular signal-regulated kinase...
Wed May 27, 2020 03:00
IJMS, Vol. 21, Pages 3795: Cognitive Deficits in Myopathies International Journal of Molecular Sciences doi: 10.3390/ijms21113795 Authors: Peristeri Aloizou Keramida Tsouris Siokas Mentis Dardiotis Myopathies represent a wide spectrum of heterogeneous diseases mainly characterized by the abnormal structure or functioning of skeletal muscle. The current paper provides a comprehensive overview of cognitive deficits observed in various myopathies by consulting the...
Wed May 27, 2020 03:00
IJMS, Vol. 21, Pages 3798: Pathogenic Pathways and Therapeutic Approaches Targeting Inflammation in Diabetic Nephropathy International Journal of Molecular Sciences doi: 10.3390/ijms21113798 Authors: Sandra Rayego-Mateos José Luis Morgado-Pascual Lucas Opazo-Ríos Melania Guerrero-Hue Cristina García-Caballero Cristina Vázquez-Carballo Sebastián Mas Ana Belén Sanz Carmen Herencia Sergio Mezzano Carmen Gómez-Guerrero Juan Antonio Moreno Jesús Egido Diabetic...
Wed May 27, 2020 03:00
IJMS, Vol. 21, Pages 3794: Leptin Signaling Affects Survival and Chemoresistance of Estrogen Receptor Negative Breast Cancer International Journal of Molecular Sciences doi: 10.3390/ijms21113794 Authors: Lipsey Harbuzariu Robey Huff Gottesman Gonzalez-Perez Estrogen-receptor-negative breast cancer (BCER−) is mainly treated with chemotherapeutics. Leptin signaling can influence BCER− progression, but its effects on patient survival and chemoresistance...
Wed May 27, 2020 03:00
IJMS, Vol. 21, Pages 3792: New data on spermatogenic cyst formation and cellular composition of the testis in a marine gastropod, Littorina saxatilis International Journal of Molecular Sciences doi: 10.3390/ijms21113792 Authors: Demin Bogolyubov Granovitch Mikhailova Knowledge of the testis structure is important for gastropod taxonomy and phylogeny, particularly for the comparative analysis of sympatric Littorina species. Observing fresh tissue and squashing fixed tissue...
Wed May 27, 2020 03:00
IJMS, Vol. 21, Pages 3789: Inhibition of Heparanase Expression Results in Suppression of Invasion, Migration and Adhesion Abilities of Bladder Cancer Cells International Journal of Molecular Sciences doi: 10.3390/ijms21113789 Authors: Tatsumi Miyake Shimada Fujii Hori Morizawa Nakai Anai Tanaka Konishi Fujimoto Heparan sulfate proteoglycan syndecan-1, CD138, is known to be associated with cell proliferation, adhesion, and migration in malignancies....
Wed May 27, 2020 03:00
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